Fractal analysis of CE CT lung tumours images

AIM The fractal dimension (FD) of a structure provides a measure of its complexity. This pilot study aims to determine FD values for lung cancers visualised on Computed Tomography (CT) and to assess the potential for tumour FD measurements to provide an index of tumour aggression. METHOD Pre-and post-contrast CT images of the thorax acquired from 15 patients with lung cancers of greater than 10mm were transformed to fractal dimension images using a box-counting algorithm at various scales. A region of interest (ROI) was determined covering tumour locations, which were more apparent on FD images as compared to images before processing. The average tumour FD (FDavg) was computed and compared with the intensity average before FD processing. FD values were correlated with 2 markers of tumour aggression: tumour stage and tumour uptake of fluorodeoxyglucose (FDG) as determined by Positron Emission Tomography. RESULTS For pre-contrast images, the tumour FDavg correlated with tumour stage (r = 0.537, p = 0.0387) and FDG uptake (r= 0.64, p< 0.001). FDavg decreased following contrast enhancement for most tumours. CONCLUSION Fractal analysis of CT images of lung tumours could potentially provide additional information about likely tumour aggression and so impact on clinical management decisions and choice of treatment

Roche lobe effects on the atmospheric loss of "Hot Jupiters"

Observational evidence of a hydrodynamically evaporating upper atmosphere of HD209458b (Vidal-Madjar et al. 2003; 2004) and recent theoretical studies on evaporation scenarios of ``Hot Jupiters'' in orbits around solar-like stars with the age of the Sun indicate that the upper atmospheres of short-periodic exoplanets experience hydrodynamic blow-off conditions resulting in loss rates of the order of about 10^10 - 10^12 g s^-1 (Lammer et al. 2003; Yelle 2004; Baraffe et al. 2004; Lecavlier des Etangs et al. 2004; Jaritz et al. 2005, Tian et al. 2005; Penz et al. 2007). By studying the effect of the Roche lobe on the atmospheric loss from short-periodic gas giants we found, that the effect of the Roche lobe can enhance the hydrodynamic evaporation from HD209458b by about 2 and from OGLE-TR-56b by about 2.5 times. For similar exoplanets which are closer to their host star than OGLE-TR-56b, the enhancement of the mass loss can be even larger. Moreover, we show that the effect of the Roche lobe raises the possibility that ``Hot Jupiters'' can reach blow-off conditions at temperatures which are less than expected (< 10000 K) due to the stellar X-ray and EUV (XUV) heating.Comment: 4 pages, 2 figures, submitted to A&

Estimation of the XUV radiation onto close planets and their evaporation

Context: The current distribution of planet mass vs. incident stellar X-ray flux supports the idea that photoevaporation of the atmosphere may take place in close-in planets. Integrated effects have to be accounted for. A proper calculation of the mass loss rate due to photoevaporation requires to estimate the total irradiation from the whole XUV range. Aims: The purpose of this paper is to extend the analysis of the photoevaporation in planetary atmospheres from the accessible X-rays to the mostly unobserved EUV range by using the coronal models of stars to calculate the EUV contribution to the stellar spectra. The mass evolution of planets can be traced assuming that thermal losses dominate the mass loss of their atmospheres. Methods: We determine coronal models for 82 stars with exoplanets that have X-ray observations available. Then a synthetic spectrum is produced for the whole XUV range (~1-912 {\AA}). The determination of the EUV stellar flux, calibrated with real EUV data, allows us to calculate the accumulated effects of the XUV irradiation on the planet atmosphere with time, as well as the mass evolution for planets with known density. Results: We calibrate for the first time a relation of the EUV luminosity with stellar age valid for late-type stars. In a sample of 109 exoplanets, few planets with masses larger than ~1.5 Mj receive high XUV flux, suggesting that intense photoevaporation takes place in a short period of time, as previously found in X-rays. The scenario is also consistent with the observed distribution of planet masses with density. The accumulated effects of photoevaporation over time indicate that HD 209458b may have lost 0.2 Mj since an age of 20 Myr. Conclusions: Coronal radiation produces rapid photoevaporation of the atmospheres of planets close to young late-type stars. More complex models are needed to explain fully the observations.Comment: Accepted by A&A. 10 pages, 8 figures, 7 Tables (2 online). Additional online material includes 7 pages, 6 figures and 6 tables, all include

Hot-Jupiters and hot-Neptunes: a common origin?

We compare evolutionary models for close-in exoplanets coupling irradiation and evaporation due respectively to the thermal and high energy flux of the parent star with observations of recently discovered new transiting planets. The models provide an overall good agreement with observations, although at the very limit of the quoted error bars of OGLE-TR-10, depending on its age. Using the same general theory, we show that the three recently detected hot-Neptune planets (GJ436, $\rho$ Cancri, $\mu$ Ara) may originate from more massive gas giants which have undergone significant evaporation. We thus suggest that hot-Neptunes and hot-Jupiters may share the same origin and evolution history. Our scenario provides testable predictions in terms of the mass-radius relationships of these hot-Neptunes.Comment: 5 pages, 2 figures, accepted in A&A Lette

Planetary evaporation by UV & X-ray radiation: basic hydrodynamics

We consider the evaporation of close in planets by the star's intrinsic EUV and X-ray radiation. We calculate evaporation rates by solving the hydrodynamical problem for planetary evaporation including heating from both X-ray and EUV radiation. We show that most close-in planets (a<0.1 AU) are evaporating hydrodynamically, with the evaporation occurring in two distinct regimes: X-ray driven, in which the X-ray heated flow contains a sonic point, and EUV driven, in which the X-ray region is entirely sub-sonic. The mass-loss rates scale as L_X/a^2 for X-ray driven evaporation, and as Phi_*^{1/2}/a for EUV driven evaporation at early times, with mass-loss rates of order 10e10-10e14 g/s. No exact scaling exists for the mass-loss rate with planet mass and planet radius, however, in general evaporation proceeds more rapidly for planets with lower densities and higher masses. Furthermore, we find that in general the transition from X-ray driven to EUV driven evaporation occurs at lower X-ray luminosities for planets closer to their parent stars and for planets with lower densities. Coupling our evaporation models to the evolution of the high energy radiation - which falls with time - we are able to follow the evolution of evaporating planets. We find that most planets start off evaporating in the X-ray driven regime, but switch to EUV driven once the X-ray luminosity falls below a critical value. The evolution models suggest that while `hot Jupiters' are evaporating, they are not evaporating at a rate sufficient to remove the entire gaseous envelope on Gyr time-scales. However, we do find that close in Neptune mass planets are more susceptible to complete evaporation of their envelopes. Thus we conclude that planetary evaporation is more important for lower mass planets, particularly those in the `hot Neptune'/`super Earth' regime.Comment: 18 Pages, Accepted for publication in MNRA

Service evaluation of the GOALS family-based childhood obesity treatment intervention during the first 3 years of implementation.

Objectives: To evaluate the impact of the GOALS (Getting Our Active Lifestyles Started) family-based childhood obesity treatment intervention during the first 3 years of implementation. Design: Single-group repeated measures with qualitative questionnaires. Setting: Community venues in a socioeconomically deprived, urban location in the North-West of England. Participants: 70 overweight or obese children (mean age 10.5 years, 46% boys) and their parents/carers who completed GOALS between September 2006 and March 2009. Interventions: GOALS was a childhood obesity treatment intervention that drew on social cognitive theory to promote whole family lifestyle change. Sessions covered physical activity (PA), diet and behaviour change over 18 2 h weekly group sessions (lasting approximately 6 months). A Template for Intervention Description and Replication (TIDieR) checklist of intervention components is provided. Primary and secondary outcome measures: The primary outcome measure was child body mass index (BMI) z-score, collected at baseline, post-intervention and 12 months. Secondary outcome measures were child selfperceptions, parent/carer BMI and qualitative changes in family diet and PA (parent/carer questionnaire). Results: Child BMI z-score reduced by 0.07 from baseline to post-intervention (p<0.001) and was maintained at 12 months (p<0.05). There was no change in parent/carer BMI or child self-perceptions, other than an increase in perceived social acceptance from baseline to post-intervention (p<0.05). Parents/carers reported positive changes to family PA and dietary behaviours after completing GOALS. Conclusions: GOALS completion was associated with small improvements in child BMI z-score and improved family PA and dietary behaviours. Several intervention modifications were necessary during the implementation period and it is suggested childhood obesity treatment interventions need time to embed before a definitive evaluation is conducted. Researchers are urged to use the TIDieR checklist to ensure transparent reporting of interventions and facilitate the translation of evidence to practice

Risky Business: Motivations for Markets in Programmable Networks

Abstract. We believe that the problems of safety, security and resource usage combine to make it unlikely that programmable networks will ever be viable without mechanisms to transfer risk from the platform provider to the user and the programmer. However, we have well established mechanisms for managing risk -markets. In this paper we argue for the establishment of markets to manage the risk in running a piece of software and to ensure that the risk is reflected on all the stakeholders. We describe a strawman architecture for third party computation in the programmable network. Within this architecture, we identify two major novel features:-Dynamic price setting, and a reputation service. We investigate the feasibility of these features and provide evidence that a practical system can indeed be built. Our contributions are in the argument for markets providing a risk management mechanism for programmable networks, the development of an economic model showing incentives for developing better software, and in the first analysis of a real transaction graph for reputation systems from an Internet commerce site

A scenario of planet erosion by coronal radiation

Context: According to theory, high-energy emission from the coronae of cool stars can severely erode the atmospheres of orbiting planets. No observational tests of the long term effects of erosion have yet been made. Aims: To analyze the current distribution of planetary mass with X-ray irradiation of the atmospheres in order to make an observational assessment of the effects of erosion by coronal radiation. Methods: We study a large sample of planet-hosting stars with XMM-Newton, Chandra and ROSAT; make a careful identification of X-ray counterparts; and fit their spectra to make accurately measurements of the stellar X-ray flux. Results: The distribution of the planetary masses with X-ray flux suggests that erosion has taken place: most surviving massive planets, (M_p sin i >1.5 M_J), have been exposed to lower accumulated irradiation. Heavy erosion during the initial stages of stellar evolution is followed by a phase of much weaker erosion. A line dividing these two phases could be present, showing a strong dependence on planet mass. Although a larger sample will be required to establish a well-defined erosion line, the distribution found is very suggestive. Conclusions: The distribution of planetary mass with X-ray flux is consistent with a scenario in which planet atmospheres have suffered the effects of erosion by coronal X-ray and EUV emission. The erosion line is an observational constraint to models of atmospheric erosion.Comment: A&A 511, L8 (2010). 4 pages, 3 figures, 1 online table (included). Language edited; corrected a wrong unit conversion (g/s -> M_J/Gyr); corrected values in column 12 of Table 1 (slightly underestimated in first version), and Figure 2 updated accordingl

Solar Particle Acceleration at Reconnecting 3D Null Points

Context: The strong electric fields associated with magnetic reconnection in solar flares are a plausible mechanism to accelerate populations of high energy, non-thermal particles. One such reconnection scenario occurs at a 3D magnetic null point, where global plasma flows give rise to strong currents in the spine axis or fan plane. Aims: To understand the mechanism of charged particle energy gain in both the external drift region and the diffusion region associated with 3D magnetic reconnection. In doing so we evaluate the efficiency of resistive spine and fan models for particle acceleration, and find possible observables for each. Method: We use a full orbit test particle approach to study proton trajectories within electromagnetic fields that are exact solutions to the steady and incompressible magnetohydrodynamic equations. We study single particle trajectories and find energy spectra from many particle simulations. The scaling properties of the accelerated particles with respect to field and plasma parameters is investigated. Results: For fan reconnection, strong non-uniform electric drift streamlines can accelerate the bulk of the test particles. The highest energy gain is for particles that enter the current sheet, where an increasing "guide field" stabilises particles against ejection. The energy is only limited by the total electric potential energy difference across the fan current sheet. The spine model has both slow external electric drift speed and weak energy gain for particles reaching the current sheet. Conclusions: The electromagnetic fields of fan reconnection can accelerate protons to the high energies observed in solar flares, gaining up to 0.1 GeV for anomalous values of resistivity. However, the spine model, which gave a harder energy spectrum in the ideal case, is not an efficient accelerator after pressure constraints in the resistive model are included.Comment: 15 pages, 14 figures. Submitted to Astronomy and Astrophysic

Mass-loss rates for transiting exoplanets

Exoplanets at small orbital distances from their host stars are submitted to intense levels of energetic radiations, X-rays and extreme ultraviolet (EUV). Depending on the masses and densities of the planets and on the atmospheric heating efficiencies, the stellar energetic inputs can lead to atmospheric mass loss. These evaporation processes are observable in the ultraviolet during planetary transits. The aim of the present work is to quantify the mass-loss rates (dm/dt), heating efficiencies (eta), and lifetimes for the whole sample of transiting exoplanets, now including hot jupiters, hot neptunes, and hot super-earths. The mass-loss rates and lifetimes are estimated from an "energy diagram" for exoplanets, which compares the planet gravitational potential energy to the stellar X/EUV energy deposited in the atmosphere. We estimate the mass-loss rates of all detected transiting planets to be within 10^6 to 10^13 g/s for various conservative assumptions. High heating efficiencies would imply that hot exoplanets such the gas giants WASP-12b and WASP-17b could be completely evaporated within 1 Gyr. We further show that the heating efficiency can be constrained when dm/dt is inferred from observations and the stellar X/EUV luminosity is known. This leads us to suggest that eta ~ 100% in the atmosphere of the hot jupiter HD209458b, while it could be lower for HD189733b. Simultaneous observations of transits in the ultraviolet and X-rays are necessary to further constrain the exospheric properties of exoplanets.Comment: 10 pages, 5 figures, 2 tables. Accepted for publication in Astronomy & Astrophysic