3,288 research outputs found

    Employee Age as a Moderator of the Relationship Between Ambition and Work Role Affect

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    Past research has demonstrated a negative relationship between ambition, or the desire to get ahead, and job satisfaction. In the present paper, age was hypothesized to moderate the relationship between ambition and job satisfaction such that the relationship between ambition and satisfaction is more negative for older employees than for younger employees. Three studies, with three criterion variables (promotion satisfaction, extrinsic job satisfaction, overall job satisfaction), were used to test the hypothesis. Results indicated support for the hypothesized interaction. The discussion focuses on the implications of the results for organizational and individual career management strategies

    Varieties of vacua in classical supersymmetric gauge theories

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    We give a simple description of the classical moduli space of vacua for supersymmetric gauge theories with or without a superpotential. The key ingredient in our analysis is the observation that the lagrangian is invariant under the action of the complexified gauge group \Gc. From this point of view the usual DD-flatness conditions are an artifact of Wess--Zumino gauge. By using a gauge that preserves \Gc invariance we show that every constant matter field configuration that extremizes the superpotential is \Gc gauge-equivalent (in a sense that we make precise) to a unique classical vacuum. This result is used to prove that in the absence of a superpotential the classical moduli space is the algebraic variety described by the set of all holomorphic gauge-invariant polynomials. When a superpotential is present, we show that the classical moduli space is a variety defined by imposing additional relations on the holomorphic polynomials. Many of these points are already contained in the existing literature. The main contribution of the present work is that we give a careful and self-contained treatment of limit points and singularities.Comment: 14 pages, LaTeX (uses revtex.sty

    Mapping 6D N = 1 supergravities to F-theory

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    We develop a systematic framework for realizing general anomaly-free chiral 6D supergravity theories in F-theory. We focus on 6D (1, 0) models with one tensor multiplet whose gauge group is a product of simple factors (modulo a finite abelian group) with matter in arbitrary representations. Such theories can be decomposed into blocks associated with the simple factors in the gauge group; each block depends only on the group factor and the matter charged under it. All 6D chiral supergravity models can be constructed by gluing such blocks together in accordance with constraints from anomalies. Associating a geometric structure to each block gives a dictionary for translating a supergravity model into a set of topological data for an F-theory construction. We construct the dictionary of F-theory divisors explicitly for some simple gauge group factors and associated matter representations. Using these building blocks we analyze a variety of models. We identify some 6D supergravity models which do not map to integral F-theory divisors, possibly indicating quantum inconsistency of these 6D theories.Comment: 37 pages, no figures; v2: references added, minor typos corrected; v3: minor corrections to DOF counting in section

    Nongeometric Flux Compactifications

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    We investigate a simple class of type II string compactifications which incorporate nongeometric "fluxes" in addition to "geometric flux" and the usual H-field and R-R fluxes. These compactifications are nongeometric analogues of the twisted torus. We develop T-duality rules for NS-NS geometric and nongeometric fluxes, which we use to construct a superpotential for the dimensionally reduced four-dimensional theory. The resulting structure is invariant under T-duality, so that the distribution of vacua in the IIA and IIB theories is identical when nongeometric fluxes are included. This gives a concrete framework in which to investigate the possibility that generic string compactifications may be nongeometric in any duality frame. The framework developed in this paper also provides some concrete hints for how mirror symmetry can be generalized to compactifications with arbitrary H-flux, whose mirrors are generically nongeometric.Comment: 26 pages, JHEP3. v3: references, minor corrections, and clarifications added. v4: sign correcte

    Comparison of Biomarker Expression between Proximal and Distal Colorectal Adenomas: The Tennessee-Indiana Adenoma Recurrence Study

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    It is unclear if proximal and distal traditional adenomas present with differences in molecular events which contribute to cancer heterogeneity by tumor anatomical subsite. Participants from a colonoscopy-based study (n=380) were divided into subgroups based on the location of their most advanced adenoma: proximal, distal, or “equivalent both sides”. Eight biomarkers in the most advanced adenomas were evaluated by immunohistochemistry (Ki-67, COX-2, TGFβRII, EGFR, β-catenin, cyclin D1, c-Myc) or TUNEL (apoptosis). After an adjustment for pathological features, there were no significant differences between proximal and distal adenomas for any biomarker. Conversely, expression levels did vary by other features, such as their size, villous component, and synchronousness. Large adenomas had higher expression levels of Ki-67(P<0.001), TGFβRII (P<0.0001), c-Myc (P<0.001), and cyclin D1 (P<0.001) in comparison to small adenomas, and tubulovillous/villous adenomas also were more likely to have similar higher expression levels in comparison to tubular adenomas. Adenoma location is not a major determinant of the expression of these biomarkers outside of other pathological features. This study suggests similarly important roles of Wnt/β-catenin and TGF-β pathways in carcinogenesis in both the proximal and distal colorectum

    Differences in Quadriceps Activation During Return-to-play in Lower Body Resistance-Trained Females

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    Muscular activation in the quadriceps is indicative of proper muscular function, which is the sole determinant of a return-to-play assessment. Specifically, the activation within the knee extensors is essential to the evaluation of ACL tears. PURPOSE: The purpose of the study was to bilaterally compare muscular activation of the vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF) during isokinetic knee extensions across velocities. METHODS: 8 lower-body resistance-trained females (n=8; age= 19 ±1, height= 169.06 ±3.85 cm, weight= 64.46 ±4.76 kg) completed this study. Using an isokinetic dynamometer, subjects performed continuous isokinetic knee extensions at velocities of 60°/sec, 180°/sec, and 240°/sec. Three separate 4-pin surface electromyography (EMG) sensors were used to record activation within the VL, VM, and RF during the protocol. Average root mean squared (RMS) values were calculated via manual editing techniques across the contractions at all three velocities. A three-way mixed factorial analysis of variance (ANOVA) (velocity [60°/sec v 180°/sec v 240°/sec] x muscle [VL v VM v RF] x leg [dominant v non-dominant]) was used to compare average RMS values during the differing velocities. RESULTS: There were no significant velocity x muscle x leg interactions (p\u3e0.05) in the RMS values. However, when collapsed by muscle and leg, there was a significant main effect (p\u3c0.05) for muscle activation at each separate velocity. CONCLUSION: These could be due to evaluation and EPOC windows during manual editing techniques, which account for potential electromechanical delays and onset of torque production

    Strings between branes

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    D-brane configurations containing fundamental strings are constructed as classical solutions of Yang-Mills theory. The fundamental strings in these systems stretch between D-branes. In the case of D1-branes, this construction gives smooth (classical) resolutions of string junctions and string networks. Using a non-abelian Yang-Mills analysis of the string current, the string charge density is computed and is shown to have support in the region between the D-brane world-volumes. The 't Hooft-Polyakov monopole is analyzed using similar methods, and is shown to contain D-strings whose flux has support off the D-brane world-volume defined by the Higgs scalar field, when this field is interpreted in terms of a transverse dimension. The constructions presented here are used to give a qualitative picture of tachyon condensation in the Yang-Mills limit, where fundamental strings and lower-dimensional D-branes arise in a volume of space-time where brane-antibrane annihilation has occurred.Comment: 35 pages, 16 eps figures, JHEP style; v2: a comment adde

    Decreased mental time travel to the past correlates with default-mode network disintegration under lysergic acid diethylamide

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    This paper reports on the effects of LSD on mental time travel during spontaneous mentation. Twenty healthy volunteers participated in a placebo-controlled crossover study, incorporating intravenous administration of LSD (75 μg) and placebo (saline) prior to functional magnetic resonance imaging (fMRI). Six independent, blind judges analysed mentation reports acquired during structured interviews performed shortly after the functional magnetic resonance imaging (fMRI) scans (approximately 2.5 h post-administration). Within each report, specific linguistic references to mental spaces for the past, present and future were identified. Results revealed significantly fewer mental spaces for the past under LSD and this effect correlated with the general intensity of the drug’s subjective effects. No differences in the number of mental spaces for the present or future were observed. Consistent with the previously proposed role of the default-mode network (DMN) in autobiographical memory recollection and ruminative thought, decreased resting-state functional connectivity (RSFC) within the DMN correlated with decreased mental time travel to the past. These results are discussed in relation to potential therapeutic applications of LSD and related psychedelics, e.g. in the treatment of depression, for which excessive reflection on one’s past, likely mediated by DMN functioning, is symptomatic
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