717 research outputs found
Even more benefit with endovascular treatment for patients with acute ischaemic stroke:MR CLEAN-LATE
Towards equality: gender representation at the Royal College of Radiologistsâ Annual Scientific Meeting 2014-2021
Background: Conferences facilitate career advancement, but gender imbalances in public fora may negatively impact both women and men, and society. We aimed to describe the gender distribution of presenters at the UKâs 2014-2021 Royal College of Radiologistsâ (RCR) Annual Scientific Meeting. Methods: We extracted data on presenter name, role and session type from meeting programmes. We classified gender as male or female using names, records or personal pronouns, accepting the limitations of these categories. We classified roles by prestige: lead, other (speakers and workshop faculty), proffered paper or poster presenters. We calculated odds ratios (OR) and 95% confidence intervals (CI) for associations between gender and binary outcomes using logistic regression. Results: Women held 1,059 (37.5%) of 2,826 conference roles and presented 9/27 keynotes. Compared to men, women were less likely to hold other roles such as speakers and workshop faculty (OR 0.72 95% CI 0.61-0.83), and more likely to present posters (OR 1.49 95% CI 1.27-1.76). There were 60 male-only and eight women-only multi-presenter sessions. Sessions led by women had higher proportions of women speakers. The odds of roles being held by women increased during online meetings during COVID in 2020 and 2021 (OR 1.61, 95% CI 1.36-1.91) compared to earlier years. Conclusion: The proportion of women presenters and keynote speakers reflects that of RCR membership, but not of wider society. Disadvantage starts from the earliest career stages, prejudicing career opportunities. Efforts to improve inclusion and diversity are needed; focusing on lead roles and hybrid online/in-person formats may accelerate change
User guide for Inferior Frontal Sulcal Hyperintensity (IFSH) Scale and related template
This report describes the data related to the article entitiled: âRelationship between inferior frontal sulcal hyperintensities on brain MRI, ageing and cerebral small vessel diseaseâ.
1. User guide for Inferior Frontal Sulcal Hyperintensity (IFSH) Scale
This user guide with detailed definition, description and clear examples aims to rate objectively and reproducibly the amount of hyperintensity demonstrated in the CSF in the inferior frontal sulci of the brain.
2. Inferior Frontal Sulcal Hyperintensity (IFSH) Scale templat
WMH and long-term outcomes in ischemic stroke
Objective To investigate the relationship between baseline white matter hyperintensities (WMH) in patients with ischemic stroke and long-term risk of dementia, functional impairment, recurrent stroke, and mortality.
Methods Following the Meta-analysis of Observational Studies in Epidemiology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO protocol: CRD42018092857), we systematically searched Medline and Scopus for cohort studies of ischemic stroke patients examining whether MRI- or CT-assessed WMH at baseline are associated with dementia, functional impairment, recurrent stroke, and mortality at 3 months or later poststroke. We extracted data and evaluated study quality with the NewcastleâOttawa scale. We pooled relative risks (RR) for the presence and severity of WMH using random-effects models.
Results We included 104 studies with 71,298 ischemic stroke patients. Moderate/severe WMH at baseline were associated with increased risk of dementia (RR 2.17, 95% confidence interval [CI] 1.72â2.73), cognitive impairment (RR 2.29, 95% CI 1.48â3.54), functional impairment (RR 2.21, 95% CI 1.83â2.67), any recurrent stroke (RR 1.65, 95% CI 1.36â2.01), recurrent ischemic stroke (RR 1.90, 95% CI 1.26â2.88), all-cause mortality (RR 1.72, 95% CI 1.47â2.01), and cardiovascular mortality (RR 2.02, 95% CI 1.44â2.83). The associations followed dose-response patterns for WMH severity and were consistent for both MRI- and CT-defined WMH. The results remained stable in sensitivity analyses adjusting for age, stroke severity, and cardiovascular risk factors, in analyses of studies scoring high in quality, and in analyses adjusted for publication bias.
Conclusions Presence and severity of WMH are associated with substantially increased risk of dementia, functional impairment, stroke recurrence, and mortality after ischemic stroke. WMH may aid clinical prognostication and the planning of future clinical trials
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