Review of Performance Pay at County Level Public Hospitals

Performance pay in county-level public hospitals is an important part of the reform of public hospitals, which largely determines the success or failure of the reform of public hospitals. This paper reviews the concept of performance pay, the recognition of hospitals and staff, the main performance pay model, current situation, design principles and ideas in County-level Public hospitals, and provides some reference for future research and reform direction of performance pay in County-level Public hospitals

Virasoro hair and entropy for axisymmetric Killing horizons

We show that the gravitational phase space for the near-horizon region of a bifurcate, axisymmetric Killing horizon in any dimension admits a 2D conformal symmetry algebra with central charges proportional to the area. This extends the construction of [Haco et. al., JHEP 12, 098 (2018)] to generic Killing horizons appearing in solutions of Einstein's equations, and motivates a holographic description in terms of a 2D conformal field theory. The Cardy entropy in such a field theory agrees with the Bekenstein-Hawking entropy of the horizon, suggesting a microscopic interpretation.Comment: 6+4 pages, 2 columns, 1 figure, v2: included a derivation of integrability of the horizon charges, added appendix on the near-horizon expansion for Kerr, references added; updated to match published versio

Digital supply chain: literature review of seven related technologies

This paper systematically reviews literature related with digital supply chains (DSC) and investigates the application status and development trend of different digital technologies in supply chain management. The review is conducted from the perspective of seven key digital supply chain technologies, i.e. Internet of Things (IoT) & Radio Frequency Identification (RFID), 5th Generation Mobile Communication Technology (5G), 3D Printing, Big data (BD), Blockchain, Digital Twins (DT), and Intelligent autonomous vehicles (IAVs). It highlights the main limitations and opportunities of the various DSC technologies, provides an overview of prior studies, and identifies knowledge gaps by outlining the advantages, weaknesses and restrictions of individual technology. The paper also aims at providing a development framework as a roadmap for the match of different digital technologies with different strategic goals

High-Power and Ultralong-Life Aqueous Zinc-Ion Hybrid Capacitors Based on Pseudocapacitive Charge Storage

© 2019, © 2019, The Author(s). Rechargeable aqueous zinc-ion hybrid capacitors and zinc-ion batteries are promising safe energy storage systems. In this study, amorphous RuO2·H2O for the first time was employed to achieve fast and ultralong-life Zn2+ storage based on a pseudocapacitive storage mechanism. In the RuO2·H2O||Zn zinc-ion hybrid capacitors with Zn(CF3SO3)2 aqueous electrolyte, the RuO2·H2O cathode can reversibly store Zn2+ in a voltage window of 0.4–1.6 V (vs. Zn/Zn2+), delivering a high discharge capacity of 122 mAh g−1. In particular, the zinc-ion hybrid capacitors can be rapidly charged/discharged within 36 s with a very high power density of 16.74 kW kg−1 and a high energy density of 82 Wh kg−1. Besides, the zinc-ion hybrid capacitors demonstrate an ultralong cycle life (over 10,000 charge/discharge cycles). The kinetic analysis elucidates that the ultrafast Zn2+ storage in the RuO2·H2O cathode originates from redox pseudocapacitive reactions. This work could greatly facilitate the development of high-power and safe electrochemical energy storage.[Figure not available: see fulltext.]

Characterizing HMW-GS alleles of decaploid Agropyron elongatum in relation to evolution and wheat breeding

Bread wheat quality is mainly correlated with high molecular weight glutenin subunits (HMW-GS) of endosperm. The number of HMW-GS alleles with good processing quality is limited in bread wheat cultivars, while there are plenty of HMW-GS alleles in wheat-related grasses to exploit. We report here on the cloning and characterization of HMW-GS alleles from the decaploid Agropyron elongatum. Eleven novel HMW-GS alleles were cloned from the grass. Of them, five are x-type and six y-type glutenin subunit genes. Three alleles Aex4, Aey7, and Aey9 showed high similarity with another three alleles from the diploid Lophopyrum elongatum, which provided direct evidence for the Ee genome origination of A. elongatum. It was noted that C-terminal regions of three alleles of the y-type genes Aey8, Aey9, and Aey10 showed more similarity with x-type genes than with other y-type genes. This demonstrates that there is a kind of intermediate state that appeared in the divergence between x- and y-type genes in the HMW-GS evolution. One x-type subunit, Aex4, with an additional cysteine residue, was speculated to be correlated with the good processing quality of wheat introgression lines. Aey4 was deduced to be a chimeric gene from the recombination between another two genes. How the HMW-GS genes of A. elongatum may contribute to the improvement of wheat processing quality are discussed

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Background The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function. Results Here, we report on the results of the third CAFA challenge, CAFA3, that featured an expanded analysis over the previous CAFA rounds, both in terms of volume of data analyzed and the types of analysis performed. In a novel and major new development, computational predictions and assessment goals drove some of the experimental assays, resulting in new functional annotations for more than 1000 genes. Specifically, we performed experimental whole-genome mutation screening in Candida albicans and Pseudomonas aureginosa genomes, which provided us with genome-wide experimental data for genes associated with biofilm formation and motility. We further performed targeted assays on selected genes in Drosophila melanogaster, which we suspected of being involved in long-term memory. Conclusion We conclude that while predictions of the molecular function and biological process annotations have slightly improved over time, those of the cellular component have not. Term-centric prediction of experimental annotations remains equally challenging; although the performance of the top methods is significantly better than the expectations set by baseline methods in C. albicans and D. melanogaster, it leaves considerable room and need for improvement. Finally, we report that the CAFA community now involves a broad range of participants with expertise in bioinformatics, biological experimentation, biocuration, and bio-ontologies, working together to improve functional annotation, computational function prediction, and our ability to manage big data in the era of large experimental screens.Peer reviewe

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

BackgroundThe Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function.ResultsHere, we report on the results of the third CAFA challenge, CAFA3, that featured an expanded analysis over the previous CAFA rounds, both in terms of volume of data analyzed and the types of analysis performed. In a novel and major new development, computational predictions and assessment goals drove some of the experimental assays, resulting in new functional annotations for more than 1000 genes. Specifically, we performed experimental whole-genome mutation screening in Candida albicans and Pseudomonas aureginosa genomes, which provided us with genome-wide experimental data for genes associated with biofilm formation and motility. We further performed targeted assays on selected genes in Drosophila melanogaster, which we suspected of being involved in long-term memory.ConclusionWe conclude that while predictions of the molecular function and biological process annotations have slightly improved over time, those of the cellular component have not. Term-centric prediction of experimental annotations remains equally challenging; although the performance of the top methods is significantly better than the expectations set by baseline methods in C. albicans and D. melanogaster, it leaves considerable room and need for improvement. Finally, we report that the CAFA community now involves a broad range of participants with expertise in bioinformatics, biological experimentation, biocuration, and bio-ontologies, working together to improve functional annotation, computational function prediction, and our ability to manage big data in the era of large experimental screens.</p

Review of Performance Pay at County Level Public Hospitals

Performance pay in county-level public hospitals is an important part of the reform of public hospitals, which largely determines the success or failure of the reform of public hospitals. This paper reviews the concept of performance pay, the recognition of hospitals and staff, the main performance pay model, current situation, design principles and ideas in County-level Public hospitals, and provides some reference for future research and reform direction of performance pay in County-level Public hospitals

Comparison of a foreign hypermarket and local heartland stores in Singapore : why do customers prefer one to the other?

This study aims to explore whether there is any difference in customers' perceptions of these foreign retailers and that of Singapore retailers, and if there is, what are the factors leading to such difference

Optimization of production system of shale oil development in Ordos basin, China

Abstract In this paper, production system (PS) of shale oil is optimized according to production data and indoor experiments, including core and fluid tests. Results showed that: ① Pressure drop rate at wellhead is a reasonable reference for the determination of post-fracture shut-in duration (PFSID). When pressure at a wellhead of horizontal well is relatively stable and the pressure drop less than 0.1 MPa per day for three consecutive days, PFSID ends; ② Flowback intensity of fracturing fluid affects the effectiveness of proppant underground, thus flowback intensity can be determined by the critical flow rate and safety factor of each proppant; ③ Flowback intensity should be varied during different development stages, which could be divided into four according to production gas and oil ratio(GOR) of a shale oil horizontal well: low, medium–high, high and high-low production GOR. During the stage of low production GOR, ratio of flow pressure and saturation pressure should be maintained greater than 1.0, and the initial daily liquid productivity for a hundred-meter oil-bearing lateral length in a horizontal well is 2.4 ~ 2.9 m3/d; and during the medium–high production GOR, high production GOR and high-low production GOR stages, the responding initial daily liquid productivity should be maintained between 0.8 ~ 1.0 or less than 0.8 respectively