42,824 research outputs found
Wantagh Union Free School District and Wantagh Registered Professional Nurses Association
WANTAGH UNION FREE SCHOOL DISTRICT, Employer, and WANTAGH REGISTERED PROFESSIONAL NURSES ASSOCIATION, Union. Case No. M2008-191.m2008_191.pdf: 333 downloads, before Oct. 1, 2020
Patchogue-Medford Library and Library Unit, CSEA Local 1000, AFL-CIO, Local 852
In the matter of the fact-finding between the Patchogue-Medford Library, employer, and the Library Unit, CSEA Local 1000, AFL-CIO, Local 852, union. PERB case no. M2010-104. Before: Owen B. Walsh, fact finder
Encoding of temporal probabilities in the human brain
Anticipating the timing of future events is a necessary precursor to preparing actions and allocating resources to sensory processing. This requires elapsed time to be represented in the brain and used to predict the temporal probability of upcoming events. While neuropsychological, imaging, magnetic stimulation studies, and single-unit recordings implicate the role of higher parietal and motor-related areas in temporal estimation, the role of earlier, purely sensory structures remains more controversial. Here we demonstrate that the temporal probability of expected visual events is encoded not by a single area but by a wide network that importantly includes neuronal populations at the very earliest cortical stages of visual processing. Moreover, we show that activity in those areas changes dynamically in a manner that closely accords with temporal expectations
Combined riblet and lebu drag reduction system
The invention is a system of flow control devices which result in reduced skin friction on aerodynamic and hydrodynamic surfaces. The devices cause a breakup of large-scale disturbances in the boundary layer of the flow field. The riblet device acts to reduce disturbances near the boundary layer wall by the use of longitudinal striations forming V-shaped grooves. These grooves are dimensional on the order of the wall vortices and turbulent burst dimensions. The large eddy breakup device is a small strip or airfoil which is suspended in the upper region of the boundary layer. Various physical mechanisms cause a disruption of the large-scale vortices. The combination of the devices of this invention result in a substantial reduction in skin friction drag
Cultural dislocation & consequences. An exploratory study of illicit drug activity in a Traveller community in north Dublin.
The misuse of drugs among our community here in Dublin 15 is of great concern to Blanchardstown Traveller Development Group and it is a concern for Traveller families and for the community as a whole. Traveller’s are a marginalised group in Irish society and are one of the most excluded groups socially and culturally in the country and this is no different here in Dublin 15. What is different is the impact that the misuse of drugs is having on our community.
Travellers make up less than one percent of the national population, mostly live in extended families on Traveller sites so when drugs hit our community its more visible and public, so fear of looking for support is harder and this research has identified some of these issues. This research has also identified the type of drug misuse which means we can now start to look at the local responses and supports that are needed to address these serious issues which are having a very negative effect on individuals, parents, families and on the community. The research has identified the local issues and made clear recommendations that need to be acted upon
Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access. The development of an economic and effective product relies on a balanced consideration of the risks and benefits of these factors. This review provides a comprehensive and up-to-date analysis of oral dosage forms considering key aspects of formulation design including dosage considerations, ease of use, tolerability and safety, manufacturing complexity, stability, supply and cost. Patient acceptability has been examined utilising an evidence-based approach to evaluate regulatory guidance and literature. Safety considerations including excipients and potential risk of administration errors of the different dosage forms are also discussed, together with possible manufacturing and supply challenges. Age appropriate drug product design should consider and compare i) acceptability ii) safety and iii) access, although it is important to recognise that these factors must be balanced against each other, and in some situations a compromise may need to be reached when selecting an age-appropriate formulation.Peer reviewedFinal Accepted Versio
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