2,007 research outputs found
Following one's heart: cardiac rhythms gate central initiation of sympathetic reflexes
Central nervous processing of environmental stimuli requires integration of sensory information with ongoing autonomic control of cardiovascular function. Rhythmic feedback of cardiac and baroreceptor activity contributes dynamically to homeostatic autonomic control. We examined how the processing of brief somatosensory stimuli is altered across the cardiac cycle to evoke differential changes in bodily state. Using functional magnetic resonance imaging of brain and noninvasive beat-to-beat cardiovascular monitoring, we show that stimuli presented before and during early cardiac systole elicited differential changes in neural activity within amygdala, anterior insula and pons, and engendered different effects on blood pressure. Stimulation delivered during early systole inhibited blood pressure increases. Individual differences in heart rate variability predicted magnitude of differential cardiac timing responses within periaqueductal gray, amygdala and insula. Our findings highlight integration of somatosensory and phasic baroreceptor information at cortical, limbic and brainstem levels, with relevance to mechanisms underlying pain control, hypertension and anxiety
Response process and test-retest reliability of the Context Assessment for Community Health tool in Vietnam
Background: The recently developed Context Assessment for Community Health (COACH) tool aims to measure aspects of the local healthcare context perceived to influence knowledge translation in low- and middle-income countries. The tool measures eight dimensions (organizational resources , community engagement, monitoring services for action, sources of knowledge, commitment to work, work culture, leadership, and informal payment) through 49 items. Objective: The study aimed to explore the understanding and stability of the COACH tool among health providers in Vietnam. Designs: To investigate the response process, think-aloud interviews were undertaken with five community health workers, six nurses and midwives, and five physicians. Identified problems were classified according to Conrad and Blair's taxonomy and grouped according to an estimation of the magnitude of the problem's effect on the response data. Further, the stability of the tool was examined using a test–retest survey among 77 respondents. The reliability was analyzed for items (intraclass correlation coefficient (ICC) and percent agreement) and dimensions (ICC and Bland–Altman plots). Results: In general, the think-aloud interviews revealed that the COACH tool was perceived as clear, well organized, and easy to answer. Most items were understood as intended. However, seven prominent problems in the items were identified and the content of three dimensions was perceived to be of a sensitive nature. In the test–retest survey, two-thirds of the items and seven of eight dimensions were found to have an ICC agreement ranging from moderate to substantial (0.5–0.7), demonstrating that the instrument has an acceptable level of stability. Conclusions: This study provides evidence that the Vietnamese translation of the COACH tool is generally perceived to be clear and easy to understand and has acceptable stability. There is, however, a need to rephrase and add generic examples to clarify some items and to further review items with low ICC.Duong M. Duc, Anna Bergström, Leif Eriksson, Katarina Selling, Bui Thi Thu Ha and Lars Walli
Vortex glass transition in a random pinning model
We study the vortex glass transition in disordered high temperature
superconductors using Monte Carlo simulations. We use a random pinning model
with strong point-correlated quenched disorder, a net applied magnetic field,
longrange vortex interactions, and periodic boundary conditions. From a finite
size scaling study of the helicity modulus, the RMS current, and the
resistivity, we obtain critical exponents at the phase transition. The new
exponents differ substantially from those of the gauge glass model, but are
consistent with those of the pure three-dimensional XY model.Comment: 7 pages RevTeX, 4 eps figure
Current--Voltage Characteristics of Two--Dimensional Vortex Glass Models
We have performed Monte Carlo simulations to determine current--voltage
characteristics of two different vortex glass models in two dimensions. The
results confirm the conclusions of earlier studies that there is a transition
at . In addition we find that, as , the linear resistance vanishes
exponentially, and the current scale, , where non-linearities appear in
the -- characteristics varies roughly as , quite different from the
predictions of conventional flux creep theory, . The results for
the two models agree quite well with each other, and also agree fairly well
with recent experiments on very thin films of YBCO.Comment: 18 pages with 10 figures available upon request from R. A. Hyman at
[email protected]. The only change in the new version is the
deletion of an unimportant comment.IUCM94-01
Resistance scaling at the Kosterlitz-Thouless transition
We study the linear resistance at the Kosterlitz-Thouless transition by Monte
Carlo simulation of vortex dynamics. Finite size scaling analysis of our data
show excellent agreement with scaling properties of the Kosterlitz-Thouless
transition. We also compare our results for the linear resistance with
experiments. By adjusting the vortex chemical potential to an optimum value,
the resistance at temperatures above the transition temperature agrees well
with experiments over many decades.Comment: 7 pages, 4 postscript figures included, LATEX, KTH-CMT-94-00
Temporal and spatial carbon dioxide concentration patterns in a small boreal lake in relation to ice-cover dynamics
Global carbon dioxide (CO2) emission estimates from inland waters commonly neglect the ice-cover season. To account for CO2 accumulation below ice and consequent emissions into the atmosphere at ice-melt we combined automatically-monitored and manually- sampled spatially-distributed CO2 concentration measurements from a small boreal ice-covered lake in Sweden. In early winter, CO2 accumulated continuously below ice, whereas, in late winter, CO2 concentrations remained rather constant. At ice-melt, two CO2 concentration peaks were recorded, the first one reflecting lateral CO2 transport within the upper water column, and the second one reflecting vertical CO2 transport from bottom waters. We estimated that 66%–85% of the total CO2 accumulated in the water below ice left the lake at ice-melt, while the remainder was stored in bottom waters. Our results imply that CO2 accumulation under ice and emissions at ice-melt are more dynamic than previously reported, and thus need to be more accurately integrated into annual CO2 emission estimates from inland waters
Non-Universality in Random Matrix Ensembles with Soft Level Confinement
Two families of strongly non-Gaussian random matrix ensembles (RME) are
considered. They are statistically equivalent to a one-dimensional plasma of
particles interacting logarithmically and confined by the potential that has
the long-range behavior (),
or . The direct Monte Carlo simulations on
the effective plasma model shows that the spacing distribution function (SDF)
in such RME can deviate from that of the classical Gaussian ensembles. For
power-law potentials, this deviation is seen only near the origin , while for the double-logarithmic potential the SDF shows the cross-over
from the Wigner-Dyson to Poisson behavior in the bulk of the spectrum.Comment: 4 pages, REVTEX, 3 postscript figures appended, ICTP/9/94/ckw.
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