310 research outputs found
Basic taste processing recruits bilateral anteroventral and middle dorsal insulae: An activation likelihood estimation meta-analysis of fMRI studies
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The Changing Landscape of Neuroscience Research, 2006–2015: A Bibliometric Study
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At the Leading Front of Neuroscience: A Bibliometric Study of the 100 Most-Cited Articles
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Self-tuning neurofuzzy control for nonlinear systems with offset
A self-tuning neurofuzzy controller with an ability to remove offsets is derived in this paper based on the self-tuning integrating controller derived for the local linear model. The training target for the proposed controllers is derived, and they can be trained by the simplified recursive least squares (RLS) method with a computing time that is linear instead of geometric in the number of weights in the network. Further, the simplified RLS method not only has the same convergence property as the RLS method, it also has a better ability in tracking varying parameters. The performance of the self-tuning neurofuzzy controller is illustrated by examples involving both linear and nonlinear systems.published_or_final_versio
Fault detection of redundant systems based on B-spline neural network
The fault detection and isolation of redundant sensor systems based on B-spline neural networks is presented in this paper. The network is trained using an algorithm with an adaptive learning rate. To further save computation time, the residual vector is transformed from a multivariate B-spline function to an univariate B-spline function. The detection of abrupt and drifting faults using the proposed method is discusses. The performance of the proposed method is illustrated by an example involving a redundant system consisting of six sensors.published_or_final_versio
Diagnostic accuracy of mediastinal width measurement on posteroanterior and anteroposterior chest radiographs in the depiction of acute nontraumatic thoracic aortic dissection
We aimed to explore the diagnostic accuracy of various mediastinal measurements in determining acute nontraumatic thoracic aortic dissection with respect to posteroanterior (PA) and anteroposterior (AP) chest radiographs, which had received little attention so far. We retrospectively reviewed 100 patients (50 PA and 50 AP chest radiographs) with confirmed acute thoracic aortic dissection and 120 patients (60 PA and 60 AP chest radiographs) with confirmed normal aorta. Those who had prior history of trauma or aortic disease were excluded. The maximal mediastinal width (MW) and maximal left mediastinal width (LMW) were measured by two independent radiologists and the mediastinal width ratio (MWR) was calculated. Statistical analysis was then performed with independent sample t test. PA projection was significantly more accurate than AP projection, achieving higher sensitivity and specificity. LMW and MW were the most powerful parameters on PA and AP chest radiographs, respectively. The optimal cutoff levels were LMW = 4.95 cm (sensitivity, 90 %; specificity, 90 %) and MW = 7.45 cm (sensitivity, 90 %; specificity, 88.3 %) for PA projection and LMW = 5.45 cm (sensitivity, 76 %; specificity, 65 %) and MW = 8.65 cm (sensitivity, 72 %; specificity, 80 %) for AP projection. MWR was found less useful and less reliable. The use of LMW alone in PA film would allow more accurate prediction of aortic dissection. PA chest radiograph has a higher diagnostic accuracy when compared with AP chest radiograph, with negative PA chest radiograph showing less probability for aortic dissection. Lower threshold for proceeding to computed tomography aortogram is recommended however, especially in the elderly and patients with widened mediastinum on AP chest radiograph. © 2012 The Author(s).published_or_final_versio
Effects of Cyclosporine and Tacrolimus on the Pharmacokinetics of Mycophenolic Acid in Renal Transplant Recipients
Anti-beta2 glycoprotein I (beta2GPI) antibodies facilitates phagocytosis of apoptotic neutrophils in patients with systemic lupus erythematosus (SLE)
BACKGROUND : Increased apoptosis provides a continuous source autoantigens and has been suggested to have a pathogenic role in SLE. We have previously shown patients with SLE have impaired clearance of apoptotic bodies. In this study, we evaluated whether anti-beta2GPI antibodies, a subset of antiphospholipid antibodies, may have an effect on the phagocytosis of apoptotic bodies by macrophages in these patients …published_or_final_versio
Sex hormones and apoptosis and immunoglobulin production in systemic lupus erythematosus
BACKGROUND: SLE is an autoimmune disease that affects predominantly female of reproductive age. Previous studies have suggested an immunomodulatory role of sex hormones in the pathogenesis of SLE. Objectives: To examine the effects of various sex hormones on apoptosis and immunoglobulin production by peripheral blood mononuclear cells (PBMCs) in SLE patients …published_or_final_versio
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