51 research outputs found
Jorge A. Swieca's contributions to quantum field theory in the 60s and 70s and their relevance in present research
After revisiting some high points of particle physics and QFT of the two
decades from 1960 to 1980, I comment on the work by Jorge Andre Swieca. I
explain how it fits into the quantum field theory during these two decades and
draw attention to its relevance to the ongoing particle physics research. A
particular aim of this article is to direct thr readers mindfulness to the
relevance of what at the time of Swieca was called "the Schwinger Higgs
screening mechanism". which, together with recent ideas which generalize the
concept of gauge theories, has all the ingredients to revolutionize the issue
of gauge theories and the standard model.Comment: 49 pages, expansion and actualization of text, improvement of
formulations and addition of many references to be published in EPJH -
Historical Perspectives on Contemporary Physic
Evaluation of central vestibular syndrome in dogs using brainstem auditory evoked responses recorded with surface electrodes
Persistência do plano experimental em ensaios de avaliação de germoplasma elite de feijão
A critical look at 50 years particle theory from the perspective of the crossing property
The crossing property is perhaps the most subtle aspect of the particle-field
relation. Although it is not difficult to state its content in terms of certain
analytic properties relating different matrixelements of the S-matrix or
formfactors, its relation to the localization- and positive energy spectral
principles requires a level of insight into the inner workings of QFT which
goes beyond anything which can be found in typical textbooks on QFT. This paper
presents a recent account based on new ideas derived from "modular
localization" including a mathematic appendix on this subject. Its main novel
achievement is the proof of the crossing property of formfactors from a
two-algebra generalization of the KMS condition. The main content of this
article is the presentation of the derailments of particle theory during more
than 4 decades: the S-matrix bootstrap, the dual model and its string theoretic
extension. Rather than being related to crossing, string theory is the (only
known) realization of a dynamic infinite component one-particle wave function
space and its associated infinite component field. Here "dynamic" means that,
unlike a mere collection of infinitely many irreducible unitary Poincar\'e
group representation or free fields, the formalism contains also operators
which communicate between the different irreducible Poincar\'e represenations
(the levels of the "infinite tower") and set the mass/spin spectrum. Wheras in
pre-string times there were unsuccessful attempts to achieve this in analogy to
the O(4,2) hydrogen spectrum by the use of higher noncompact groups, the
superstring in d=9+1, which uses instead (bosonic/fermionic) oscillators
obtained from multicomponent chiral currents is the only known unitary positive
energy solution of the dynamical infinite component pointlike localized field
project.Comment: 66 pages, addition of new results, addition of references, will
appear in this form in Foundations of Physic
Physics with the KLOE-2 experiment at the upgraded DANE
Investigation at a --factory can shed light on several debated issues
in particle physics. We discuss: i) recent theoretical development and
experimental progress in kaon physics relevant for the Standard Model tests in
the flavor sector, ii) the sensitivity we can reach in probing CPT and Quantum
Mechanics from time evolution of entangled kaon states, iii) the interest for
improving on the present measurements of non-leptonic and radiative decays of
kaons and eta/eta mesons, iv) the contribution to understand the
nature of light scalar mesons, and v) the opportunity to search for narrow
di-lepton resonances suggested by recent models proposing a hidden dark-matter
sector. We also report on the physics in the continuum with the
measurements of (multi)hadronic cross sections and the study of gamma gamma
processes.Comment: 60 pages, 41 figures; added affiliation for one of the authors; added
reference to section
The comorbidity and co-medication profile of patients with progressive supranuclear palsy
Background
Progressive supranuclear palsy (PSP) is usually diagnosed in elderly. Currently, little is known about comorbidities and the co-medication in these patients.
Objectives
To explore the pattern of comorbidities and co-medication in PSP patients according to the known different phenotypes and in comparison with patients without neurodegenerative disease.
Methods
Cross-sectional data of PSP and patients without neurodegenerative diseases (non-ND) were collected from three German multicenter observational studies (DescribePSP, ProPSP and DANCER). The prevalence of comorbidities according to WHO ICD-10 classification and the prevalence of drugs administered according to WHO ATC system were analyzed. Potential drug–drug interactions were evaluated using AiDKlinik®.
Results
In total, 335 PSP and 275 non-ND patients were included in this analysis. The prevalence of diseases of the circulatory and the nervous system was higher in PSP at first level of ICD-10. Dorsopathies, diabetes mellitus, other nutritional deficiencies and polyneuropathies were more frequent in PSP at second level of ICD-10. In particular, the summed prevalence of cardiovascular and cerebrovascular diseases was higher in PSP patients. More drugs were administered in the PSP group leading to a greater percentage of patients with polypharmacy. Accordingly, the prevalence of potential drug–drug interactions was higher in PSP patients, especially severe and moderate interactions.
Conclusions
PSP patients possess a characteristic profile of comorbidities, particularly diabetes and cardiovascular diseases. The eminent burden of comorbidities and resulting polypharmacy should be carefully considered when treating PSP patients
Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management
Growing evidence suggests an increasing significance for the extent of gastrointestinal tract (GIT) dysfunction in Parkinson’s disease (PD). Most patients suffer from GIT symptoms, including dysphagia, sialorrhea, bloating, nausea, vomiting, gastroparesis, and constipation during the disease course. The underlying pathomechanisms of this α-synucleinopathy play an important role in disease development and progression, i.e., early accumulation of Lewy pathology in the enteric and central nervous systems is implicated in pharyngeal discoordination, esophageal and gastric motility/peristalsis impairment, chronic pain, altered intestinal permeability and autonomic dysfunction of the colon, with subsequent constipation. Severe complications, including malnutrition, dehydration, insufficient drug effects, aspiration pneumonia, intestinal obstruction, and megacolon, frequently result in hospitalization. Sophisticated diagnostic tools are now available that permit more detailed examination of specific GIT impairment patterns. Furthermore, novel treatment approaches have been evaluated, although high-level evidence trials are often missing. Finally, the burgeoning literature devoted to the GIT microbiome reveals its importance for neurologists. We review current knowledge about GIT pathoanatomy, pathophysiology, diagnosis, and treatment in PD and provide recommendations for management in daily practice
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