86 research outputs found

    Closed Reduction of Bilateral Posterior Shoulder Dislocation with Medium Impression Defect of the Humeral Head: A Case Report and Review of Its Treatment

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    Bilateral dislocation of the shoulder is a rare injury. The main causes are electrical shock, extreme trauma, and epilepsy. A 25-year-old athletic-body man had sustained bilateral shoulder pain and restricted external rotation following electrical shock for five days. Although articular surface damage was about 50% in the right side and 30% in the left, it could be managed successfully by close reduction without pinning. During one-year follow-up, no recurrent dislocation or limitation of motion was seen. Closed management of medium size defect of the humeral head after posterior dislocation can be performed in cooperative and especially muscular patients

    Exploring the Relationship among EFL Teachers’ Critical Thinking, Autonomy and Experience in Public and Private Schools

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    The research delved into the connection between English Language instructors’ critical thinking, autonomy, and teaching experience among some public and private instructors. Two different sets of instructors including some private institute and high school instructors were selected from two major cities in Khorasan Razavi, Iran. The results from Path Analysis indicated that all subcomponents of instructors’ thinking critically except deduction could significantly predict instructors’ independence. Moreover, experience more effectively and remarkably predicted their independence. Accordingly, from among the five subcomponents of instructors’ CT, four sub-constituents were predicated by experience. Nevertheless, assessment and evaluation could not be properly predicted by experience. Findings also indicated that thinking critically could rightly and moderately be related to autonomy whereas there was a positively weak association between thinking critically and experience. Accordingly, findings pointed to a sizeable distinction between the two EFL settings regarding instructors’ autonomous behavior with non-public EFL instructors being more self-sufficient, selfdirected, and self-reliant than their counterparts in public high schools. In the same vein, there was no substantial distinction between the two settings concerning thinking critically

    Implementation of absolute quantification in small-animal SPECT imaging: Phantom and animal studies

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    Purpose: Presence of photon attenuation severely challenges quantitative accuracy in single-photon emission computed tomography (SPECT) imaging. Subsequently, various attenuation correction methods have been developed to compensate for this degradation. The present study aims to implement an attenuation correction method and then to evaluate quantification accuracy of attenuation correction in small-animal SPECT imaging. Methods: Images were reconstructed using an iterative reconstruction method based on the maximum-likelihood expectation maximization (MLEM) algorithm including resolution recovery. This was implemented in our designed dedicated small-animal SPECT (HiReSPECT) system. For accurate quantification, the voxel values were converted to activity concentration via a calculated calibration factor. An attenuation correction algorithm was developed based on the first-order Chang’s method. Both phantom study and experimental measurements with four rats were used in order to validate the proposed method. Results: The phantom experiments showed that the error of �15.5% in the estimation of activity concentration in a uniform region was reduced to +5.1% when attenuation correction was applied. For in vivo studies, the average quantitative error of �22.8 � 6.3% (ranging from �31.2% to �14.8%) in the uncorrected images was reduced to +3.5 � 6.7% (ranging from �6.7 to +9.8%) after applying attenuation correction. Conclusion: The results indicate that the proposed attenuation correction algorithm based on the first-order Chang’s method, as implemented in our dedicated small-animal SPECT system, significantly improves accuracy of the quantitative analysis as well as the absolute quantification

    Epidemiološki pokazatelji i sprečavanje trauma s posljedicom amputacije prsta: studija bolničkih podataka

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    Traumatic finger amputation is a widespread preventable public health problem. This study aimed to define the epidemiology of finger amputations to identify important related factors in order to suggest pertinent prevention strategies. A cross-sectional study was conducted in 2015 at the main orthopedic referral university hospital of Shiraz. All patients with any type of traumatic finger amputation were included. For each patient a questionnaire including demographic and injury characteristics was filled and analyzed. One hundred patients (92 men and 8 women, mean age: 32.5 ± 18 years) were enrolled. The vast majority of subjects were young men, more than half (53 cases) sustained occupation-related injuries during working time. Finger amputation following severe jammed finger in door was the second most frequent damage (18 %). Approximately 59% of victims labeled inattention during work as the reason of injury. Finger amputations in right hand were equal in frequency to the left one. Amputation of the index and middle fingers were seen as the most common amputated fingers in hands, 27% and 26% respectively. It was found that young beginner worker man with low educational level is at the highest risk of traumatic finger amputation especially with positive history of drug abusing. So, effective interventions such as closer supervision, more training programs, detection of drug addiction, and using safe engineering machines are urgently needed.Amputacija prsta čest je javnozdravstveni problem koji je moguće spriječiti. Studija definira epidemiologiju amputacije prsta kako bi se utvrdili najvažniji čimbenici i predložila strategija prevencije. Studija je provedena 2015. u glavnoj sveučilišnoj ortopedskoj bolnici u Shirazu. U studiju su bili uključeni svi bolesnici s bilo kojom vrstom amputacije prsta. Za svakog bolesnika je popunjen i analiziran upitnik s demografskim podacima i tipom ozljede. Sudjelovalo je 100 bolesnika (92 muškarca i 9 žena, prosječne dobi 32.5 ± 18 godina). Najveći broj bolesnika bili su mlađi muškarci. Više od polovice (53 slučaja) pretrpjeli su ozljede na radu u vezi s radom. Amputacija prsta zbog nagnječenja u vratima bila je drugi najčešći uzrok amputacije (18 %). Približno 59 % ozlijeđenih navelo je nepažnju pri radu kao uzrok nezgode. Amputacije prsta desne ruke bile su brojčano jednake amputacijama na lijevoj ruci. Najviše je bilo amputacija kažiprsta (27 %) i srednjeg prsta (2 %). Utvrđeno je da su mlađi, slabije obrazovani muškarci te početnici na poslu podložni najvećem riziku od amputacije prstiju, naročito ako imaju povijest zlouporabe droga. Hitno je potrebno provesti sljedeće učinkovite mjere: veći nadzor, više programa osposobljavanja, otkrivanje ovisnosti o drogama i korištenje sigurnijih strojeva

    Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis

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    Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO have not been systemically reviewed. In this study we systematically reviewed and assessed the quality of studies reporting the incidence and/or prevalence of NMO across the world. Methods. A comprehensive literature search using MEDLINE, EMBASE, and Web of Science for the terms “Neuromyelitis optica,” “devic disease,” “incidence,” “prevalence,” and “epidemiology” was conducted on January 31, 2015. Study quality was assessed using an assessment tool based on recognized guidelines and designed specifically for this study. Results. A total of 216 studies were initially identified, with only 9 meeting the inclusion criteria. High level of heterogeneity amongst studies precluded a firm conclusion. Incidence data were found in four studies and ranged from 0.053 per 100,000 per year in Cuba to 0.4 in Southern Denmark. Prevalence was reported in all studies and ranged from 0.51 per 100,000 in Cuba to 4.4 in Southern Denmark. Conclusion. This review reveals the gaps that still exist in the epidemiological knowledge of NMO in the world. Published studies have different qualities and methodology precluding a robust conclusion. Future researches focusing on epidemiological features of NMO in different nations and different ethnic groups are needed

    Implementation of absolute quantification in small-animal SPECT imaging: Phantom and animal studies

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    Purpose: Presence of photon attenuation severely challenges quantitative accuracy in single-photon emission computed tomography (SPECT) imaging. Subsequently, various attenuation correction methods have been developed to compensate for this degradation. The present study aims to implement an attenuation correction method and then to evaluate quantification accuracy of attenuation correction in small-animal SPECT imaging. Methods: Images were reconstructed using an iterative reconstruction method based on the maximum-likelihood expectation maximization (MLEM) algorithm including resolution recovery. This was implemented in our designed dedicated small-animal SPECT (HiReSPECT) system. For accurate quantification, the voxel values were converted to activity concentration via a calculated calibration factor. An attenuation correction algorithm was developed based on the first-order Chang’s method. Both phantom study and experimental measurements with four rats were used in order to validate the proposed method. Results: The phantom experiments showed that the error of �15.5% in the estimation of activity concentration in a uniform region was reduced to +5.1% when attenuation correction was applied. For in vivo studies, the average quantitative error of �22.8 � 6.3% (ranging from �31.2% to �14.8%) in the uncorrected images was reduced to +3.5 � 6.7% (ranging from �6.7 to +9.8%) after applying attenuation correction. Conclusion: The results indicate that the proposed attenuation correction algorithm based on the first-order Chang’s method, as implemented in our dedicated small-animal SPECT system, significantly improves accuracy of the quantitative analysis as well as the absolute quantification

    Sludge quality in wastewater treatment plant in Shokohieh industrial Park of Qom province in Iran

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    The general attitude of the wastewater treatment process in our country is focus on the effluent quality and unfortunately waste sludge quality is rarely considered. Since multiple natural hazards and routes the contact with sludge requires a comprehensive approach to protect public health and the environment. The aim of this study is an assessment of sludge management and finding out the potential use of sludge for land application. The study was conducted in January to December 2014. samples were gathered in four seasons, winter, spring, summer and autumn from wastewater treatment plant in industrial park of Shokohieh of Qom province according to the instructions in standard method. Sampling was moments and composite. Numbers of Samples were 24 that 2 samples were captured in every month. Samples measured base on standard method for water wastewater examination references and then data was analyzed by SPSS and t-test. The results show that the Physical Parameters qualities and nutrients qualities in sludge are good. The Phosphate quality is not suitable. Based on t-test, the results show that levels of fecal coliform and total coliform in cold and warm seasons are different (

    An evaluation of hospital admission respiratory disease attributed to sulfur dioxide ambient concentration in Ahvaz from 2011 through 2013

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    There is no doubt that air pollutants have adverse impacts on human health. The main objective of this study was to evaluate hospital admission respiratory disease (HARD) attributed to sulfur dioxide levels in Ahvaz during three successive years. Data was taken from Iranian Environmental Protection Agency (EPA). The AirQ2,2,3 model is used to quantify the impact of SO2 on inhabitants of Ahvaz and in terms of hospital admission respiratory diseases. This is a kind of statistical model which is based on some epidemiological indices such as relative risk, baseline incidence, and attributable proportion. Sampling was already performed for 24 h in four stations during 2011–2013. Four stations are good representative for residential, high traffic, industry, and background sites which cover the whole area of the Ahvaz city. Regarding to gravimetric scale, raw data of sulfur dioxide was processed using Excel software. Encoding, filtering, and processing were conducted to prepare input file for the Air Q2,2,3 model. After running model,1 Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2 Environmental Technologies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 3 Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran 4 Razi Teaching Hospital, Clinical Research Development Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 5 Department of Internal Medicine, Division of Pulmonology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 6 Nutrition&Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 7 Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran 8 Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran 9 Department of Environmental Health Engineering, Faculty of Health, Bushehr University of Medical Sciences, Bushehr, Iran 10 The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Research Center, Bushehr University of Medical Sciences, Bushehr, Iran 11 Hyperlipidemia Research Center, Department of Laboratory Sciences School of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran 12 Environmental Research Institute, Academic Center for Education, Culture and Research (ACECR), Rasht, Iran 13 Department of Anaesthesiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 14 Occupational Hazards Control Research Center and Department of Environmental Health Engineering, School of Public Health Environmental, Shahid Beheshti University of Medical Sciences, Tehran, Iran 15 Faculty of Food Science & Technology, Tehran University, Tehran, Iran 16 Student Research Committee, Department of Environmental Health Engineering, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Environ Sci Pollut Res DOI 10.1007/s11356-016-7447-xoutputs presented in term of hospital admissions respiratory cases. Based on our result, the highest mean and maximum of seasonal and annual levels for sulfur dioxide were observed in 2013. We concluded that obnoxious quality of fuel and some deficiencies in maintenance and operation of industries lead to worse quality of ambient air especially in 2013. Cumulative cases of HARD attributed to sulfur dioxide level at central of relative risk (RR) were estimated 24, 25, and 30 persons for 2011, 2012, and 2013, respectively. The finding of this study showed that total mean of sulfur dioxide was higher than standard concentration. We also noticed that wintertime concentrations of sulfur dioxide during three successive years were higher than of those levels in summer

    Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition.

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    Statins are some of the most widely used drugs worldwide, but one of their major side effects is myotoxicity. Using mouse myoblast (C2C12) and human alveolar rhabdomyosarcoma cell lines (RH30) in both 2-dimensional (2D) and 3-dimensional (3D) cell culture, we investigated the mechanisms of simvastatin\u27s myotoxicity. We found that simvastatin significantly reduced cell viability in C2C12 cells compared to RH30 cells. However, simvastatin induced greater apoptosis in RH30 compared to C2C12 cells. Simvastatin-induced cell death is dependent on geranylgeranyl pyrophosphate (GGPP) in C2C12 cells, while in RH30 cells it is dependent on both farnesyl pyrophosphate (FPP) and GGPP. Simvastatin inhibited autophagy flux in both C2C12 and RH30 cells and inhibited lysosomal acidification in C2C12 cells, while autophagy inhibition with Bafilomycin-A1 increased simvastatin myotoxicity in both cell lines. Simvastatin induced greater cell death in RH30 cells compared to C2C12 in a 3D culture model with similar effects on autophagy flux as in 2D culture. Overall, our results suggest that simvastatin-induced myotoxicity involves both apoptosis and autophagy, where autophagy serves a pro-survival role in both cell lines. The sensitivity to simvastatin-induced myotoxicity differs between 2D and 3D culture, demonstrating that the cellular microenvironment is a critical factor in regulating simvastatin-induced cell death in myoblasts
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