1,273 research outputs found
The Use of Real Estate for the Settlement of Claims in Roman Palestine
The Mishna in Tractate Gittin discusses land qualities, in a context where land is used to settle monetary obligations. The law is that land of different qualities must be used to pay claimants in different situations; in particular, claimants pursuant to a tort case have the right to have their claim paid with land of the best quality. Creditors have the right to be paid with land of medium quality, while women who are owed money as part of a ketuba (marriage contract) claim may have to be satisfied with land of the lowest quality. However, the total value of the land received by each claimant is just the amount they are owed it is independent of the quality of the land that is used to pay them. This being the case, the purpose of the legislation is unclear. In this paper, I explore the possibility that the law is designed to minimize the total amount of transactions costs.Land markets, Law, religion and economics, Market microstructure, mishna, sasanian babylonia, Talmud
An experimental documentation of a separated trailing-edge flow at a transonic Mach number
A detailed experiment on the separated flow field at a sharp trailing edge is described and documented. The separated flow is a result of sustained adverse pressure gradients. The experiment was conducted using an elongated airfoil-like model at a transonic Mach number and at a high Reynolds number of practical interest. Measurements made include surface pressures and detailed mean and turbulence flow quantities in the region just upstream of separation to downstream into the near-wake, following wake closure. The data obtained are presented mostly in tabular form. These data are of sufficient quality and detail to be useful as a test case for evaluating turbulence models and calculation methods
Specific Antibodies to Recombinant Allergens of \u3cem\u3eAspergillus fumigatus\u3c/em\u3e in Cystic Fibrosis Patients with ABPA
Background
Aspergillus fumigatus, a widely distributed fungus, has been implicated in causing life threatening infections as well as severe asthma and allergic diseases in man. Allergic affliction like allergic bronchopulmonary aspergillosis (ABPA) is a disabling lung disease frequently seen in patients with asthma and cystic fibrosis. Immunodiagnosis of the former is comparatively easier due to the availability of purified antigens and sensitive methods. However, this is not true with cystic fibrosis patients where the prevalence of ABPA is fairly high and the morbidity and mortality are significant. Methods
In the present study, we have evaluated purified recombinant allergens from A. fumigatus, namely Asp f 1, f 2, f 3, f 4, and f 6 using ELISA and a semi-automated method (ImmunoCAP). We studied 17 patients each from cystic fibrosis with ABPA, and cystic fibrosis with asthma, 22 cystic fibrosis with no ABPA or asthma, and 11 age matched controls. Results
The results indicate that no antigen, antibody or method is capable of differentiating cystic fibrosis (CF) with ABPA from other CF patients, although some allergens showed strong reaction or showed more prevalence among the patients studied. Conclusion
When results of several allergens such as Asp f 1, f 2, f 3, f 4, and f 6 in their binding to IgA, IgG, and IgE antibodies were analyzed, a more strong discrimination of CF patients with ABPA was possible from the other groups studied
An experimental documentation of trailing-edge flows at high Reynolds number
Experiments documenting attached trailing-edge and near-wake flows at high Reynolds numbers are described. A long, airfoil-like model was tested at subsonic and low transonic Mach numbers, and both symmetrical and asymmetrical flows with pressure gradients upstream of the trailing edge were investigated. Model surface pressures and detailed mean and turbulence flow qualities were measured in the vicinity of the trailing edge and in the near-wake. The data obtained are of sufficient quality and detail to be useful as test cases in assessing turbulence models and calculation methods
Formulation, optimization and characterization of Betaxolol hydrochloride proniosomes using 3-2 factorial design
The revolution in nanotechnology has lead to the development of various dosage forms such as vesicular drug delivery and in particular liposomes, niosomes, proniosomes, aquasomes, bilosomes etc. The disad-vantages exhibited by the liposomes, niosomes can be overcome through introduction of proniosomes which are compact liquid crystalline structures and convert to niosomes upon hydration. The investigation is focused on development and optimization of Betaxolol proniosomes using three square factorial design technique with the aid of design expert 11.0 ® trial version. The optimization technique prefers choles-terol and span 60 as independent variables and drug content, vesicular size, and entrapment efficacy as dependent variables. The design generated total 13 formulations among which F10 exhibited 98.1% drug content and 97.3% of entrapment efficacy. In view of other parameters, F10 exhibits 6.5 pH, 3.8 ve-sicular size and follows diffusion mechanism with anomalous drug transport. Hence, the obtained results specify that F10 is optimized and can be opted for commercialization
Optimisation of Diesel Engine for Hybrid Military Tracked Vehicles using Matlab-Simulink
The demand in the technology requirements for diesel engines is growing keeping hybrid vehicles in mind. In future the diesel engine no longer drives the wheels directly; as a result the engine can be engaged at a limited number of operating points, thus, offering an opportunity to optimise the fuel efficiency and performance at those operating points. The extent to which this optimisation is possible is limited by practical considerations. Also if the positive and negative power peaks in vehicle during mobility (e.g. acceleration and regenerative braking respectively) can be accommodated by high-power batteries, then the size of the engine can be considerably reduced. The engine’s operating points depend on the power-control strategy. The consequences of modifications to these operating points will have an effect on performance and efficiency. As in series hybrid only a limited number of operating points are involved and dynamic performance requirements are not imposed on the diesel engine, significant improvements can be achieved by the optimisation of the diesel engine at these operating points. The feasibility of optimisation of the engine at these operating points can be done by modification on the injection systems, the valve timings and other such parameters. This kind of approach requires the use of complex and repeated experimental analysis of the engine which is costly, cumbersome and time consuming. An alternative to this kind of experimental approach is to develop a simulation model of the engine with the generator in Matlab- Simulink
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