DIFFERENCES BETWEEN TRAINING GPS TO MANAGE DEPRESSION IN PRIMARY CARE AND ISSUING THEM WITH GUIDELINES, AND A SYSTEM OF COLLABORATIVE CARE IN THE TREATMENT OF DEPRESSION BETWEEN PRIMARY AND SECONDARY CARE

Here we describe the differences and similarities between training General Practitioners (GPs) to manage depression in primary care and issuing them with guidelines, and a system of Collaborative care in the treatment of depression between primary and secondary care. From these we deduce the reasons why collaborative care may offer better treatment outcomes than the issuing of guidelines to GPs

Responsible Investing: A Study on Non-Economic Goals and Investors’ Characteristics

The notion of rational investment is not attuned with the idea of socially responsible investment. Incongruence with conventional investments, the SRI/sustainable investment/ethical investment is pertained to ethical, environmental and social criteria (Eccles and Viviers,2011). All investors are not single-minded for an objective of wealth creation. The welfare of society and the environment are among the other drivers of investment. In certain cases, investors do prefer sustainable development to personal financial aspects (Beal et al., 2005). The present study has primarily focused on assessing the relationship between individual investors’ attributes and their noneconomic goal in order to comprehend their socially responsible investment behaviour specifically in Indian scenario. The findings of study are useful for fund managers, regulators and researchers as study has provided useful insights regarding behaviour of Indian investors for responsible investments

Crack Detection in Cantilever Beam by Frequency based Method

AbstractDuring the last few decades, intense research on the detection of crack using the vibration based techniques has been done and various approaches have been developed by researchers. In the present paper, detection of the crack presence on the surface of beam-type structural element using natural frequency is presented. First two natural frequencies of the cracked beam have been obtained experimentally and used for detection of crack location and size. Detected crack locations and size are compared with the actual results and found to be in good agreement. Also, the effect of the crack location and the crack depth on the natural frequency is presented

Strength behaviour of fly ash mortars

Power residences of fly ash mortars have been evaluated through laboratory investigations. OPC of fifty three grade changed with magnificence F fly ash with 5 - 24 % in the increments of 4 %. The effects shown that at early age at all fly ash replacements the energy reduced with admire to regular mortar. however, after 27 days and above the mortars made with fly ash substitute up to fifteen% resulted better strength than normal OPC mortar. Fly ash alternative of 21 and 26% constantly had decrease power than ordinary mortar. It turned into observed that 10% fly ash is the most beneficial content for max electricity

Genome-wide characterization, molecular evolution and mexpression profiling of the metacaspases in potato (Solanum tuberosum L.)

Metacaspases are distant relatives of animal caspases found in plants, protozoa and fungi. Some recent studies have demonstrated that metacaspases are involved in regulating the developmental and environmentally induced programmed cell death in plants. In this study, we identified metacaspase gene family in potato (Solanum tuberosum L.) and analyzed their expression pattern in various developmental tissues and stress responses of plants. There were eight metacaspase genes identified in the Peptidase (Cysteine protease) C14 family and based upon sequence alignment and phylogenetic analysis, a systematic nomenclature of potato metacaspases (SotubMCs) has been proposed. Three of the eight candidate genes showing homology with Arabidopsis thaliana type I metacaspase, AtMC1 were given name SotubMC1, SotubMC2 and SotubMC3 as per the degree of relatedness. Similarly, the next three being homologous to A. thaliana type I metacaspase, AtMC3 were named SotubMC4, SotubMC5, and SotubMC6. The remaining two were named SotubMC7 and SotubMC8, showing significant similarity with type II metacaspases of A. thaliana, AtMC4 and AtMC9, respectively. Evolutionary divergence analysis of SotubMCs from its orthologs in seven other members of Solanaceae family as well as with A. thaliana, Vitis vinifera and Oryza sativa was also carried out. The dN/dS ratios of the orthologous pairs suggested the SotubMCs were under purifying (negative) selection in course of plant evolution. Splicing patterns of potato metacaspases were also analyzed. Amongst all SotubMCs, SotubMC2, SotubMC4, SotubMC6 and SotubMC7 genes appeared to produce multiple alternative spliced variants of different lengths. Furthermore using protein modeling tools, we have predicted the protein structure of identified metacaspases. The cis-regulatory elements analysis was also performed exhibiting the presence of development, stress and hormones related cis-elements in the promoter regions of the SotubMCs. This indicates that potato metacaspases might be playing important roles in the development, stress and hormone responsive pathways. Moreover, relative expression analysis of identified genes was carried out using qRT-PCR in various developmental tissues that also include stolons and tubers. The eight metacaspases showed differential expression in different tissues. Some of the tissues such as leaf undergoing senescence among different leaf developmental stages (immature, mature and senescent) displayed higher relative expression of some of the metacaspases, implying their involvement in leaf senescence. The expression pattern of SotubMCs under various abiotic, biotic and hormonal stresses was also analysed. The results showed that many members of the potato metacaspase gene family displayed differential expression patterns under various stress conditions. Taken together, the study could provide crucial resources for further investigations to understand the functional roles of the identified metacaspases in potato