Olsen Appointed Associate Provost for Student Success and Strategic Initiatives

On April 30, 2021, Dr. Brian Olsen will join the Provost\u27s Office as the new Associate Provost for Student Success and Strategic Initiatives. Since 2018, Professor Olsen served as the chair of the Department of Wildlife, Fisheries, and Conservation Biology, and was interim director of the trans-college Ecology and Environmental Sciences Program

Jessica Miller appointed as Associate Provost for Academic Affairs and Faculty Development

Email announcement to all UMaine employees regarding the appointment of Dr. Jessica Miller to the position of Associate Provost for Academic Affairs and Faculty Development

Letter from UMaine Provost: Spring is Coming

Email communication from John Violin, Executive Vice President for Academic Affairs and Provost, to members of the University of Maine community praising performance during the COVID-19 pandemic and looking forward to turning back to work on the Strategic Visioning and Values, Student Success Initiatives, and Define Tomorrow campaigns

Drake University Fine Arts Trio

Centennial Lecture Hall April 26, 1969 8:00p.m

Virtual Town Hall on 2021 Commencement

President Joan Ferrini-Mundy was joined by Kimberly Whitehead, Geremy Chubbuck, Benjamin Evans, Kathleen Harding-Heber, and John Volin for a Virtual Town Hall on the topic of UMaine’s 2021 Commencement plans

Virtual Budget Town Hall, Fiscal Year 2022

President Joan Ferrini-Mundy leads a Virtual Budget Town Hall in a streaming YouTube discussion from 4–5:15 p.m., May 4, 2021. The forum includes an update on the University of Maine/University of Maine, Machias Fiscal Year 2021 budget and preliminary discussion of the planning process for the Fiscal Year 2022 budget. Click the blue download button for an unedited, machine-generated English language transcript for this recording

Heart Failure Therapeutics on the Basis of a Biased Ligand of the Angiotensin-2 Type 1 Receptor Rationale and Design of the BLAST-AHF Study (Biased Ligand of the Angiotensin Receptor Study in Acute Heart Failure)

The BLAST-AHF (Biased Ligand of the Angiotensin Receptor Study in Acute Heart Failure) study is designed to test the efficacy and safety of TRV027, a novel biased ligand of the angiotensin-2 type 1 receptor, in patients with acute heart failure (AHF). AHF remains a major public health problem, and no currently-available therapies have been shown to favorably affect outcomes. TRV027 is a novel biased ligand of the angiotensin-2 type 1 receptor that antagonizes angiotensin-stimulated G-protein activation while stimulating beta-arrestin. In animal models, these effects reduce afterload while increasing cardiac performance and maintaining stroke volume. In initial human studies, TRV027 appears to be hemodynamically active primarily in patients with activation of the renin-angiotensin-aldosterone system, a potentially attractive profile for an AHF therapeutic. BLAST-AHF is an international prospective, randomized, phase IIb, dose-ranging study that will randomize up to 500 AHF patients with systolic blood pressure &gt;= 120 mm Hg and</p

Shedding light on local kinase activation

Phosphorylation is the predominant language of cell signaling. And, as with any common language, an abundance of dialects has evolved to convey complex information. We discuss here how biosensors are being used to decode this language, affording an unprecedented glimpse into spatio-temporal patterns of protein phosphorylation events within the cell

Taxa de geração de resíduos da construção civil em edificações na cidade de João Pessoa

O objetivo deste trabalho foi determinar a quantidade de resíduos da construção civil (RCC) em função da área construída da edificação, para efetuar acompanhamento e fiscalização mais eficazes da geração e destinação final em dada obra. Foi escolhida uma amostra representativa das edificações em fase de construção na cidade de João Pessoa. Uma ficha para coleta das características e acompanhamento de volume de RCC descartado ao longo do cronograma de execução da construção foi fornecida aos gestores das edificações; a partir do volume descartado pelas construtoras, determinou-se a massa de RCC gerado em cada obra utilizando uma massa unitária de 1.025 kg m-3 Os resultados indicaram uma taxa média de geração de RCC classe A de 86,27 kg m-². Ainda para os RCC classe A, foram definidos os limites inferior e superior com 90% de confiança para a taxa de geração: 62,31 e 136,02 kg m-² respectivamente. A partir desses valores, o controle da geração e disposição de RCC pode ser realizado pelos órgãos competentes, dando o indicativo de quais obras podem estar infringindo a legislação vigente no tocante à destinação de tais resíduos