Ionized gas outflows and global kinematics of low-z luminous star forming galaxies

We study the kinematic properties of the ambient ionized ISM and ionized gas outflows in a large and representative sample of local luminous and ultraluminous infrared galaxies (U/LIRGs) (58 systems, 75 galaxies), on the basis of integral field spectroscopy (IFS)-based high S/N integrated spectra at galactic and sub-galactic, i.e. star forming (SF) clumps, scales. Ambient ionized gas. The velocity dispersion of the ionized ISM in U/LIRGs ( ~ 70 kms-1) is larger than in lower luminosity local star forming galaxies ( ~ 25 kms-1). While for isolated disc LIRGs star formation appears to sustain turbulence, gravitational energy release associated to interactions and mergers plays an important role driving sigma in the U/LIRG range. We also find that the impact of an AGN in ULIRGs is strong, increasing sigma by a factor 1.5 on average. The observed weak dependency of sigma with SFR surface density for local U/LIRGs is in very good agreement with that measured in some high-z samples. Ionized outflows. The presence of ionized gas outflows in U/LIRGs seems universal based on the detection of a broad, usually blueshifted, Halpha line. AGNs in U/LIRGs are able to generate faster (x2) and more massive (x1.4) ionized gas outflows than pure starbursts. The derived ionized mass loading factors are in general below one, with only a few AGNs above this limit. Only a small fraction of the ionized material from low mass LIRGs (log(Mdyn/Msun) < 10.4) could reach the intergalactic medium, with more massive galaxies retaining the gas. The observed average outflow properties in U/LIRGs are similar to high-z galaxies of comparable SFR. In the bright SF clumps found in LIRGs, ionized gas outflows appear to be very common. For a given SFR surface density, outflows in LIRG clumps would be about one to two orders of magnitude less energetic than those launched by clumps in high-z SF galaxies.Comment: 36 pages, 20 figures, 6 tables. Accepted for publication in A&

Outflow of hot and cold molecular gas from the obscured secondary nucleus of NGC3256: closing in on feedback physics

The nuclei of merging galaxies are often deeply buried in dense layers of gas and dust. In these regions, gas outflows driven by starburst and AGN activity are believed to play a crucial role in the evolution of these galaxies. However, to fully understand this process it is essential to resolve the morphology and kinematics of such outflows. Using near-IR integral-field spectroscopy obtained with VLT/SINFONI, we detect a kpc-scale structure of high-velocity molecular hydrogen (H2) gas associated with the deeply buried secondary nucleus of the IR-luminous merger NGC3256. We show that this structure is likely the hot component of a molecular outflow, which is detected also in the cold molecular gas by Sakamoto et al. This outflow, with a molecular gas mass of M(H2)~2x10^7 Msun, is among the first to be spatially resolved in both the hot H2 gas with VLT/SINFONI and the cold CO-emitting gas with ALMA. The hot and cold components share a similar morphology and kinematics, with a hot-to-cold molecular gas mass ratio of ~6x10^-5. The high (~100 pc) resolution at which we map the geometry and velocity structure of the hot outflow reveals a biconical morphology with opening angle ~40 deg and gas spread across a FWZI~1200 km/s. Because this collimated outflow is oriented close to the plane of the sky, the molecular gas may reach maximum intrinsic outflow velocities of ~1800 km/s, with an average mass outflow rate of at least ~20 Msun/yr. By modeling the line-ratios of various near-IR H2 transitions, we show that the H2 gas in the outflow is heated through shocks or X-rays to a temperature of ~1900K. The energy needed to drive the outflow is likely provided by a hidden Compton-thick AGN or by the nuclear starburst. We show that the global kinematics of the molecular outflow in NGC3256 mimic those of CO-outflows that have been observed at low spatial resolution in starburst- and active galaxies.Comment: Accepted in Astronomy and Astrophysics (accepted 29 Aug 2014 v.3, initial submission v.1 14 March 2014), 13 pages, 8 figure

CO survey of high-z radio galaxies, revisited with ALMA: Jet-cloud Alignments and Synchrotron Brightening by Molecular Gas in the Circumgalactic Environment

Powerful radio sources associated with super-massive black holes are among the most luminous objects in the Universe, and are frequently recognized both as cosmological probes and active constituents in the evolution of galaxies. We present alignments between radio jets and cold molecular gas in the environment of distant radio galaxies, and show that the brightness of the radio synchrotron source can be enhanced by its interplay with the molecular gas. Our work is based on CO J>1 observations with the Atacama Large Millimeter/submillimeter Array (ALMA) of three radio galaxies with redshifts in the range 1.4 < z < 2.1, namely MRC 0114-211 (z = 1.41), MRC 0156-252 (z = 2.02), and MRC 2048-272 (z = 2.05). These ALMA observations support previous work that found molecular gas out to 50 kpc in the circumgalactic environment, based on a CO(1-0) survey performed with the Australia Telescope Compact Array (ATCA). The CO emission is found along the radio axes but beyond the main radio lobes. When compared to a large sample of high-z radio galaxies from the literature, we find that the presence of this cold molecular medium correlates with an increased flux-density ratio of the main vs. counter lobe. This suggest that the radio lobe brightens when encountering cold molecular gas in the environment. While part of the molecular gas is likely related to the interstellar medium (ISM) from either the host or a companion galaxy, a significant fraction of the molecular gas in these systems shows very low excitation, with r$_{2-1/1-0}$ and r$_{3-2/1-0}$ values $\lesssim$0.2. This could be part of the circumgalactic medium (CGM).Comment: Accepted for publication in ApJ (19 pages, 6 figures

The Dragonfly Galaxy. III. Jet-brightening of a High-redshift Radio Source Caught in a Violent Merger of Disk Galaxies

The Dragonfly Galaxy (MRC 0152-209), the most infrared-luminous radio galaxy at redshift z~2, is a merger system containing a powerful radio source and large displacements of gas. We present kpc-resolution data from ALMA and the VLA of carbon monoxide (6-5), dust, and synchrotron continuum, combined with Keck integral-field spectroscopy. We find that the Dragonfly consists of two galaxies with rotating disks that are in the early phase of merging. The radio jet originates from the northern galaxy and brightens when it hits the disk of the southern galaxy. The Dragonfly Galaxy therefore likely appears as a powerful radio galaxy because its flux is boosted into the regime of high-z radio galaxies by the jet-disk interaction. We also find a molecular outflow of (1100 $\pm$ 550) M$_{\odot}$/yr associated with the radio host galaxy, but not with the radio hot-spot or southern galaxy, which is the galaxy that hosts the bulk of the star formation. Gravitational effects of the merger drive a slower and longer lived mass displacement at a rate of (170 $\pm$ 40) M$_{\odot}$/yr, but this tidal debris contain at least as much molecular gas mass as the much faster outflow, namely M(H2) = (3 $\pm$ 1) x 10$^9$ (alpha(CO)/0.8) M$_{\odot}$. This suggests that both the AGN-driven outflow and mass transfer due to tidal effects are important in the evolution of the Dragonfly system. The Keck data show Ly$\alpha$ emission spread across 100 kpc, and CIV and HeII emission across 35 kpc, confirming the presence of a metal-rich and extended circumgalactic medium previously detected in CO(1-0).Comment: Accepted for publication in ApJ (15 pages, 9 figures

The E-ELT first light spectrograph HARMONI: capabilities and modes

Trabajo presentado en SPIE Astronomical Telescopes, celebrado en San Diego (California), del 26 de junio al 1 de julio de 2016HARMONI is the E-ELT's first light visible and near-infrared integral field spectrograph. It will provide four different spatial scales, ranging from coarse spaxels of 60 × 30 mas best suited for seeing limited observations, to 4 mas spaxels that Nyquist sample the diffraction limited point spread function of the E-ELT at near-infrared wavelengths. Each spaxel scale may be combined with eleven spectral settings, that provide a range of spectral resolving powers (R 3500, 7500 and 20000) and instantaneous wavelength coverage spanning the 0.5 - 2.4 ¿m wavelength range of the instrument. In autumn 2015, the HARMONI project started the Preliminary Design Phase, following signature of the contract to design, build, test and commission the instrument, signed between the European Southern Observatory and the UK Science and Technology Facilities Council. Crucially, the contract also includes the preliminary design of the HARMONI Laser Tomographic Adaptive Optics system. The instrument's technical specifications were finalized in the period leading up to contract signature. In this paper, we report on the first activity carried out during preliminary design, defining the baseline architecture for the system, and the trade-off studies leading up to the choice of baseline

Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort

Background Acute respiratory distress syndrome (ARDS) can be classified into sub-phenotypes according to different inflammatory/clinical status. Prognostic enrichment was achieved by grouping patients into hypoinflammatory or hyperinflammatory sub-phenotypes, even though the time of analysis may change the classification according to treatment response or disease evolution. We aimed to evaluate when patients can be clustered in more than 1 group, and how they may change the clustering of patients using data of baseline or day 3, and the prognosis of patients according to their evolution by changing or not the cluster.Methods Multicenter, observational prospective, and retrospective study of patients admitted due to ARDS related to COVID-19 infection in Spain. Patients were grouped according to a clustering mixed-type data algorithm (k-prototypes) using continuous and categorical readily available variables at baseline and day 3.Results Of 6205 patients, 3743 (60%) were included in the study. According to silhouette analysis, patients were grouped in two clusters. At baseline, 1402 (37%) patients were included in cluster 1 and 2341(63%) in cluster 2. On day 3, 1557(42%) patients were included in cluster 1 and 2086 (57%) in cluster 2. The patients included in cluster 2 were older and more frequently hypertensive and had a higher prevalence of shock, organ dysfunction, inflammatory biomarkers, and worst respiratory indexes at both time points. The 90-day mortality was higher in cluster 2 at both clustering processes (43.8% [n = 1025] versus 27.3% [n = 383] at baseline, and 49% [n = 1023] versus 20.6% [n = 321] on day 3). Four hundred and fifty-eight (33%) patients clustered in the first group were clustered in the second group on day 3. In contrast, 638 (27%) patients clustered in the second group were clustered in the first group on day 3.Conclusions During the first days, patients can be clustered into two groups and the process of clustering patients may change as they continue to evolve. This means that despite a vast majority of patients remaining in the same cluster, a minority reaching 33% of patients analyzed may be re-categorized into different clusters based on their progress. Such changes can significantly impact their prognosis

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality