4 research outputs found

    Enhancement strategies for transdermal drug delivery systems: current trends and applications

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    Step Wise Management of Asyndromic Tooth Agenesis with Ankyloglossia: A Case Report

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    Ankyloglossia or tongue tie refers to restricted tongue movements, diagnosed in early childhood and adolescence that may cause changes in bone growth and other orofacial tissues results in altered oral functions of the child. It also affects speech, mastication and oral hygiene as well as social environment. Patients with oligodontia and tongue tie may have psychological, aesthetic, phonetic and functional problems. A rare case of female child patient with congenital partial anodontia and associated ankyloglossia with its comprehensive step wise multidisciplinary management is presented. The patient was advised for frenectomy to relieve tongue tie and functional fixed aesthetic space maintainer at an early age and was followed-up to be treated with definitive implant prosthesis with respect to the missing teeth. Early treatment and follow-up is the key to successful rehabilitation of young patients with congenitally missing teeth and ankyloglossia. It is imperative that oral rehabilitation be started as early as possible to maintain and correct the oral functions. This clinical report describes a successful aesthetic, functional, and psychological rehabilitation of a young adolescent girl with partial anodontia in mandibular anterior region and associated extensive tongue tie with step by step surgical and prosthetic management in accordance with the physical growth pattern of patient. It also offers guidelines for comprehensive management which can be used by the treating pedodontist and oral surgeon for diagnosis and treatment of ankyloglossia and partial anodontia

    Surgical management of large radicular cyst associated with mandibular deciduous molar using platelet-rich fibrin augmentation: A rare case report

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    Radicular cysts arising from deciduous teeth are rare and usually cause a large bony defect. Autologous platelet-rich fibrin (PRF) is an easily available healing biomaterial in oral surgical defect with the new perspective of accelerated healing of a large bony defect. The present case is of unusually large radicular associated with neglected carious mandibular deciduous second molar in 10-year-old girl and its surgical management with PRF augmentation as a healing biomaterial in the bony defect. One-year follow-up showed uneventful healing and eruption of succedaneous tooth. Healing was relatively faster and facilitated by PRF placement. Furthermore, the importance of anticipatory guidance about the treatment of diseased primary teeth and their preservation gets highlighted

    Advanced Approaches of Bioactive Peptide Molecules and Protein Drug Delivery Systems

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