Strategic Management of Cerebral Arachnoid Cysts in Children in the Era of Globalisation

Introduction: Arachnoid cysts in children are incidental or symptomatic findings which can have associated neurological pathologies in children. Epileptic seizures and headache are by far the most common symptoms associated to arachnoid cysts but they can also associate cerebral palsy or facial dwarfism. Objectives: In the era of globalisation we want to highlight the importance of modern diagnostic procedures and long term strategic management of children with arachnoid cysts in order to rise their social competence and have a better quality of life. Material and methods: We searched the most important theories in the literature and the new methods in the management of the arachnoid cysts. Results: Even if surgical is necessary just in few cases, medication is needed for epileptic seizures. Many children receive neuroprotective agents while other receive antiepileptic drugs for the concomitant or associated epilepsy. For speech difficulties and movement disorders speech therapy, physical therapy and other further support is needed. Discussions and conclusions: The EEG patterns are not mandatory identic to the site of the cyst. Facial dwarfism and other genetic hallmarks need to be further investigated for rare syndromes associated to cerebral arachnoid cysts. The arachnoid cyst could be a hallmark that children brain can be more sensitive to seizures

Emerging Infection with Elizabethkingia meningoseptica in Neonate. A Case Report

Background: Elizabethkingia meningoseptica are Gram-negative rod bacteria which are commonly found in the environment. The bacteria have also been associated with nosocomial infections, having been isolated on contaminated medical equipment, especially in neonatal wards

Parkinsonian Syndrome and Toxoplasmic Encephalitis

Toxoplasmosis encephalitis in patients with human immunodeficiency virus may progress rapidly with a potentially fatal outcome. Less common neurological symptoms associated with this are Parkinsonism, focal dystonia, rubral tremor and hemichorea–hemiballismus syndrome

AIDS Related Kaposi’s Sarcoma: A 20-Year Experience in a Clinic from the South-East of Romania

Kaposi’s sarcoma (KS) was peculiarly described in the first notified cases of the acquired immunodeficiency syndrome as an opportunistic condition. However, the medical progress and the development of active antiretroviral therapy allowed the control of the HIV/AIDS epidemic, although the features of KS have changed throughout the past decades. The purpose of our study is to assess the epidemiological and clinical features of AIDS related KS in Romanian patients. A retrospective follow-up study was achieved in a single infectious diseases’ clinic from Galati—Romania, between 2001 and 2021. Referring to 290 new HIV diagnosed cases from our clinic retained in care, the prevalence of KS was 3.4%. The main characteristics of patients with KS are a median age of 33, a predominance of males, prevalent severe systemic forms of diseases, frequent association of past or concomitant tuberculosis, and context of immune reconstruction syndrome. The mortality rate was 70%. KS has occurred in patients with delayed HIV diagnoses and inadequate adherence to therapy. Early recognition of both infections, the close monitoring of latent or symptomatic tuberculosis, improving the antiretroviral adherence and raising the access to oncologic procedures in Romanian HIV patients could improve their prognosis related to KS