19 research outputs found
Justicia penal transicional y justicia penal europea. El protagonismo de las víctimas y la renuncia al Derecho penal liberal
Inside transicional justice, is actually observed, a tension between what here is defined like opposite models: victim-centrism and reo-centrism. From the analysis of differents experiences of transicional justice, and centring the actual discussion in thDentro de la justicia transicional se observa en la actualidad una tensión entre los que aquí se definen como dos modelos opuestos: el victimocentrismo y el reocentrismo. A partir del análisis de diferentes fenómenos de justicia transicional, y centrand
Justicia penal transicional y justicia penal europea. El protagonismo de las víctimas y la renuncia al Derecho penal liberal
Inside transicional justice, is actually observed, a tension between what here is defined like opposite models: victim-centrism and reo-centrism. From the analysis of differents experiences of transicional justice, and centring the actual discussion in the desicions of the European Court of Human Rigths (ECtHR), the text consider about the gestion of the past by the Criminal law, the differents ways of realize transicional justice, the dangers, the most importants needs, and the tension, when this topic is studied, with the postulates of liberal Criminal law.Dentro de la justicia transicional se observa en la actualidad una tensión entre los que aquí se definen como dos modelos opuestos: el victimocentrismo y el reocentrismo. A partir del análisis de diferentes fenómenos de justicia transicional, y centrando el debate actual en las decisiones de la Corte Europea de Derechos Humanos (CEDH), se reflexiona sobre la gestión del pasado por parte del Derecho penal, sus diferentes modos de llevarse a cabo, sus peligros y más sentidas necesidades, desde la tensión que se puede presentar, al abordar este tema, con los postulados del Derecho penal liberal
Leaf photosynthesis and respiration of three bioenergy crops in relation to temperature and leaf nitrogen: how conserved are biochemical model parameters among crop species?
Given the need for parallel increases in food and energy production from crops in the context of global change, crop simulation models and data sets to feed these models with photosynthesis and respiration parameters are increasingly important. This study provides information on photosynthesis and respiration for three energy crops (sunflower, kenaf, and cynara), reviews relevant information for five other crops (wheat, barley, cotton, tobacco, and grape), and assesses how conserved photosynthesis parameters are among crops. Using large data sets and optimization techniques, the C3 leaf photosynthesis model of Farquhar, von Caemmerer, and Berry (FvCB) and an empirical night respiration model for tested energy crops accounting for effects of temperature and leaf nitrogen were parameterized. Instead of the common approach of using information on net photosynthesis response to CO2 at the stomatal cavity (An–Ci), the model was parameterized by analysing the photosynthesis response to incident light intensity (An–Iinc). Convincing evidence is provided that the maximum Rubisco carboxylation rate or the maximum electron transport rate was very similar whether derived from An–Ci or from An–Iinc data sets. Parameters characterizing Rubisco limitation, electron transport limitation, the degree to which light inhibits leaf respiration, night respiration, and the minimum leaf nitrogen required for photosynthesis were then determined. Model predictions were validated against independent sets. Only a few FvCB parameters were conserved among crop species, thus species-specific FvCB model parameters are needed for crop modelling. Therefore, information from readily available but underexplored An–Iinc data should be re-analysed, thereby expanding the potential of combining classical photosynthetic data and the biochemical model
Justicia penal transicional y justicia penal europea: el protagonismo de las víctimas y la renuncia al Derecho penal liberal
Inside transicional justice, is actually observed, a tension between what here is defined like opposite models: victim-centrism and reo-centrism. From the analysis of differents experiences of transicional justice, and centring the actual discussion in the desicions of the European Court of Human Rigths (ECtHR), the text consider about the gestion of the past by the Criminal law, the differents ways of realize transicional justice, the dangers, the most importants needs, and the tension, when this topic is studied, with the postulates of liberal Criminal law.Dentro de la justicia transicional se observa en la actualidad una tensión entre los que aquí se definen como dos modelos opuestos: el victimocentrismo y el reocentrismo. A partir del análisis de diferentes fenómenos de justicia transicional, y centrando el debate actual en las decisiones de la Corte Europea de Derechos Humanos (CEDH), se reflexiona sobre la gestión del pasado por parte del Derecho penal, sus diferentes modos de llevarse a cabo, sus peligros y más sentidas necesidades, desde la tensión que se puede presentar, al abordar este tema, con los postulados del Derecho penal liberal
Sicurezza sul lavoro: profili penali
Parte Prima
Capitolo I
LE FONTI DELLA DISCIPLINA PENALE DELLA SICUREZZA DEL LAVORO: UN SISTEMA A PIÙ LIVELLI
Capitolo II
LA VALUTAZIONE DEL RISCHIO E IL RUOLO DELLE FONTI PRIVATE
Parte Seconda
I SOGGETTI
Capitolo III
I SOGGETTI RESPONSABILI
Capitolo IV
LA DELEGA DI FUNZIONI
Capitolo V
L’IMPRENDITORE PERSONA GIURIDICA: IL ‘SISTEMA 231’ NEL
COMBINATO DISPOSTO CON IL TESTO UNICO SALUTE E
SICUREZZA SUL LAVORO
Parte Terza
LE FATTISPECIE INCRIMINATRICI A CARATTERE GENERALE
Capitolo VI
LE CONTRAVVENZIONI DEL T.U.S.L.
Capitolo VII
CONTRAVVENZIONI EXTRA-CODICEM E MECCANISMI PREMIALI
Capitolo VIII
I DELITTI DI COMUNE PERICOLO
Capitolo IX I DELITTI DI OMICIDIO E LESIONI
Parte Quarta
LE FATTISPECIE INCRIMINATRICI SPECIALI O RELATIVE
A PARTICOLARI ESIGENZE DI TUTELA
Capitolo X LE CONTRAVVENZIONI SPECIALI
Capitolo XI LAVORI IN APPALTO
Capitolo XII LA TUTELA PENALE DEL LAVORATORE DAI RISCHI PSICOSOCIALI: STRESS DA LAVORO-CORRELATO E MOBBIN
Web-ARM: a Web-Based Interface for the Automatic Construction of QM/MM Models of Rhodopsins
This article introduces Web-ARM, a specialized, on-line available, tool designed to build quantum mechanical/molecular mechanical models of rhodopsins, a widely spread family of light-responsive proteins. Web-ARM allows to rapidly build models of rhodopsins with a documented quality and to predict trends in UV-Vis absorption maximum wavelengths, based on their excitation energies computed at the CASPT2//CASSCF/Amber level of theory. Web-ARM builds upon the recently reported, python-based a-ARM protocol [J. Chem. Theory Comput., 2019, 15, 3134-3152], and as such necessitates only a crystallographic structure or a comparative model in PDB format and a very basic knowledge of the studied rhodopsin system. The user-friendly web interface uses such input to generate congruous, gas-phase models of rhodopsins and, if requested, their mutants. We present two possible applications of Web-ARM, which showcase how the interface can be employed to assist both research and educational activities in fields at the interface between chemistry and biology. The first application shows how, through Web-ARM, research projects (e.g., rhodopsin and rhodopsin mutant screening) can be carried out in significantly less time with respect to using the required computational photochemistry tools via a command line. The second application documents the use of Web-ARM in a real-life educational/training activity, through a hands-on experience illustrating the concepts of rhodopsin color tuning
La Convenzione europea dei diritti dell'uomo e l'ordinamento italiano: problematiche attuali e prospettive per il futuro
Il volume, di interesse interdisciplinare, raccoglie contributi che riguardano problematiche cruciali del sistema di tutela previsto dalla Convenzione europea dei diritti dell'uomo, quali: la tutela multilivello dei diritti in Europa, le riforme recenti della disciplina del ricorso alla Corte di Strasburgo, e con particolare riferimento all'ordinamento italiano, l'esecuzione delle sentenze della Corte europea, l'interazione tra tale Corte e i giudici nazionali
Safety Results for Geographic Atrophy Associated with Age-Related Macular Degeneration Using Subretinal Cord Blood Platelet-Rich Plasma
Purpose: To evaluate the safety of subretinal injection of cord blood platelet-rich plasma (CB-PRP) and its possible effect in eyes affected by geographic atrophy (GA) associated with dry age-related macular degeneration (d-AMD). Design: Interventional, open-label study started in January 2021 with follow-up at 12 months (the Si.Cord Study). This study was a single-center, nonrandomized, sequential-assigned clinical trial conducted in Rome, Italy, at Fondazione Policlinico Universitario Agostino Gemelli IRCCS (ClinicalTrials.gov NCT04636853). Participants: Thirteen patients (26 eyes) with bilateral d-AMD-related GA were enrolled. One eye from each patient (with more advanced GA) underwent CB-PRP treatment, and the fellow eye was considered the control. All patients participated in follow-up at 12 months. Intervention: All 13 eyes received 23-gauge (G) vitrectomy and subretinal injection of CB-PRP using a 41-gauge needle. Main Outcomes and Measures: Best-corrected visual acuity (BCVA) with ETDRS letters, central macular thickness using OCT, and atrophic area measured on en face OCT images were assessed at baseline, 1, 3, 6, and 12 months. Results: The BCVA in the treated group was 34.46 ± 20.8 ETDRS at baseline, 40.84 ± 20.52 at 1 month, 40.07 ± 20.34 at 3 months, 39.38 ± 19.84 at 6 months, and 35.84 ± 18.38 at 12 months. In the untreated group, the BCVA was 53 ± 21.1 ETDRS letters at baseline, 51.54 ± 20.99 at 1 month, 46.62 ± 19.47 at 3 months, 46.85 ± 18.58 at 6 months, and 43.92 ± 17.97 at 12 months (2-way analysis of variance: interaction of treatment by eye or time, P = 0.084). Central macular thickness did not show a significant intereye difference at 12 months (P = 0.97). The atrophic geographic areas tended to increase in both treated and fellow eyes at 12 months (P < 0.0001). No inflammatory reaction, endophthalmitis, retinal detachment, uveitis, or other complications due to the subretinal injection of CB-PRP were observed during the follow-up. Conclusions: Subretinal injection of CB-PRP could be safely used for d-AMD in its GA form. Despite its safety, a larger cohort of patients, and probably a new way of administration, will be needed to understand whether the CB-PRP could have a role in the GA treatment. Financial Disclosure(s): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article
Modern quantum chemistry with [open]molcas
10.1063/5.0004835Journal of Chemical Physics15221214117