Field trial of the efficacy of praziquantel for the treatment of monieziosis in naturally infected sheep

The purpose of the study was to evaluate the efficacy of praziquantel at 3.75 mg/kg b.w. and 5 mg/kg b.w. in treating Moniezia expansa and to observe the appearance of the parasite in the faeces of sheep following the treatment. Thirty-six sheep (24 male + 12 female), naturally infected with Moniezia expansa, were allocated to three groups according to the following dosage regimes: Group 1-3.75 mg/kg b.w., n = 12; Group 2-5 mg/kg b.w., n = 12; Control group, n = 12. The sheep were around 6-7 months old and weighed between 17.7 - 35 kg. Sheep were randomly divided into equal groups based on mean weight and sex. Faeces were collected after 12, 36, 60, 84, 108, 132 and 156 hours and just before slaughter (final 24 hours faeces) into faecal collection bags in the treatment groups. The collected faeces were then examined macroscopically for any parasite segments and microscopically for parasite eggs. After treatment the sheep excreted parasite segments as either normal parasite forms or deformed forms (melted and capsule or rosary forms). Equal numbers of animals (3 from each group) were slaughtered 10, 11, 12 and 13 days following treatment and their intestinal contents examined for the presence of parasites. None of the treated animals either in group 1 or group 2 had strobilae or scolices of M. expansa in their intestine contents after the slaughter. In contrast, sheep in the control group had 0.5-61 ml strobilae and 1-8 scolices belonging to M. expansa, Thysaniezia giardi and Stilesia globipunctata. It was concluded that praziquantel at the dose rates used in the study was 100 % effective against Moniezia expansa

SPATIAL DISTRUBITON OF CHILDREN TREATED BY CANCER IN ZONGULDAK, TURKEY

This research is focused on the examination of child cancer cases in Zonguldak (Turkey) descriptively in epidemiological aspect thanks to GIS. Universe of the study is composed of 60 children between 0-19 years old, treated in Children Oncology Clinic of Health Application and Research Center in BEU. Whole universe was reached without selecting a sample in the study. Data were collected by using a form prepared by obtaining expert advice and they were applied to children and their parents at study dates. Results were expressed as percentages. Chi-Square test was used in intergroup comparisons, results were assessed within 95% confidence interval and p<0.05 was considered as statistically significant. Variables that were used in the study were assessed, recorded in prepared data collection form and distribution maps were produced. When disease diagnosis of the children participated in the study were evaluated, it was observed that 33.3% (n=20) were being treated for ALL, 13.3% (n=8) for Medullablastoma and 11.7% (n=7) for Hodgkin-nonHodgkin Lymphoma. It was detected that 31.7% (n=19) were in Ereğli, 31.7% (n=19) were in Central district and 18.3% (n=11) were in Çaycuma, when the places where children were living were evaluated. Statistically significant difference was found (p=0.016) comparing disease diagnosis with living place, and overall distribution map of the number of cancer cases was produced in this context. This is the first research subjecting the distribution of cancer cases for Zonguldak province