369 research outputs found
Measuring performances of linux hypervisors
Virtualization is a now proven software technology that is rapidly transforming the IT landscape and fundamentally changing the way people make computations and implement services. Recently, all major software producers (e.g.,
Microsoft and RedHat) developed or acquired virtualization technologies. Our institute (http://www.cnaf.infn.it) is a Tier1 for experiments carried on at the Large Hadron Collider at CERN (http://lhc.web.cern.ch/lhc/) and is experiencing several benefits from virtualization technologies, like improving fault tolerance, providing efficient hardware resource usage and increasing security. Currently, the virtualization solution we adopted is xen, which is well supported by the Scientific Linux distribution, widely used by the High-Energy Physics (HEP) community. Since Scientific Linux is based on RedHat ES, we felt the need to investigate performances and usability differences with the new kvm technology, recently acquired
by RedHat. The case study of this work is the Tier2 site for the LHCb experiment hosted at our institute; all major grid elements for this Tier2 run on xen virtual machines smoothly. We will investigate the impact on performance and stability that a migration to kvm would entail on the Tier2 site, as well as the effort required by a system administrator to deploy the migration
Prevenzione delle recidive nel paziente precedentemente trattato con isotretinoina orale
Gli autori presentano la loro esperienza relativa alla prevenzione delle recidive nel paziente acneico precedentemente
trattato con isotretinoina orale. In particolare,
gli autori dimostrano che, alla fine della terapia con isotretinoina orale, l'utilizzodi un retinoide topico (adapalene allo 0,1% o isotretinoina allo 0,05% o tretinoina allo 0,05%), per un periodo continuativo di 6-8 mesi, limita, in modo statisticamente significativo, la comparsa delle recidive
Hybrid rescue technique after failure of a standard multibranched stent graft
A 78-year-old woman presented with type IIIC and IIID endoleaks after endovascular treatment for a thoracoabdominal aortic aneurysm. Mating between the ruptured segments of superior mesenteric artery stent graft was performed. After failed attempts at relining the right renal artery stent graft, a hybrid approach was used to connect the side branch to the target vessel: a stent graft was deployed into the side branch of the main graft and it was temporarily occluded with a balloon. After opening the sac, a stent graft was deployed into the right renal artery and the two stent grafts were connected with a running suture. Follow-up examination performed 1 month postoperatively by computed tomography imaging confirmed the effectiveness of this treatment
Salicylic Acid Peel Incorporating Triethyl Citrate and Ethyl Linoleate in the Treatment of Moderate Acne: A New Therapeutic Approach.
BACKGROUND:
Acne affects many adolescents. Conventional therapy often results in side effects and poor adherence, and the treatment does not consider the psychological effect of acne on patients, which is comparable with that of disabling diseases.
OBJECTIVES:
To evaluate the efficacy and tolerability of a peel (30% salicylic acid, triethyl citrate and ethyl linoleate) combined with a home therapy with three topical agents (triethyl citrate, ethyl linoleate and salicylic acid 0.5% cream, lotion) in moderate acne of the face.
DESIGN:
Prospective, observational, multicenter, open-label, postmarketing, phase IV study.
METHODS:
Patients were assessed by comparing Global Acne Grading System (GAGS) score and total lesion count from 15 days before the first peel (T-15 ), after four salicylic peels (every 10 ± 2 days (T0 , T10 , T20 , T30 ), and 20 days after of the end of the study (T50 ). This treatment was associated to a home therapy.
RESULTS:
Fifty-three patients completed the study. The average GAGS score fell 49% between T-15 and T50 (p < .001). No patient withdrew for adverse events.
CONCLUSIONS:
This therapy was effective and well-tolerated in all cases. Chemo-exfoliation sessions ensured the continuous monitoring of clinical results and improved patient quality of life
Cutaneous manifestations of COVID-19: Report of three cases and a review of literature
Background: Various cutaneous manifestations have been observed in patients with COVID-19 infection. However, overall similarities in the clinical presentation of these dermatological manifestations have not yet been summarized. Objective: This review aims to provide an overview of various cutaneous manifestations in patients with COVID-19 through three case reports and a literature review. Methods: A literature search was conducted using PubMed, OVID, and Google search engines for original and review articles. Studies written in the English language that mentioned cutaneous symptoms and COVID-19 were included. Results: Eighteen articles and three additional cases reported in this paper were included in this review. Of these studies, 6 are case series and 12 are case report studies. The most common cutaneous manifestation of COVID-19 was found to be maculopapular exanthem (morbilliform), presenting in 36.1% (26/72) patients. The other cutaneous manifestations included: a papulovesicular rash (34.7%, 25/72), urticaria (9.7%, 7/72), painful acral red purple papules (15.3%, 11/72) of patients, livedo reticularis lesions (2.8%, 2/72) and petechiae (1.4%, 1/72). Majority of lesions were localized on the trunk (66.7%, 50/72), however, 19.4% (14/72) of patients experienced cutaneous manifestations in the hands and feet. Skin lesion development occurred before the onset of respiratory symptoms or COVID-19 diagnosis in 12.5% (9/72) of the patients, and lesions spontaneously healed in all patients within 10 days. Majority of the studies reported no correlation between COVID-19 severity and skin lesions. Conclusion: Infection with COVID-19 may result in dermatological manifestations with various clinical presentations, which may aid in the timely diagnosis of this infection
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