948 research outputs found
Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity
- Author
- Al-Minawi
- Albertella
- Ang
- Ang
- Arnould
- Arora
- Brabec
- Chaney
- Chijiwa
- Cullinane
- Dabholkar
- Damia
- Damsma
- Dunand-Sauthier
- Ferry
- Friedberg
- Furuta
- Geoerger
- Gillet
- Jamieson
- Jung
- Jung
- Kirschner
- Köberle
- Leibeling
- Marone
- McHugh
- Mello
- Mu
- Orelli
- Page
- Plumb
- Rabik
- Reardon
- Reedijk
- Ritter
- Sancar
- Sandy
- Schneider
- Shachar
- Todd
- Usanova
- Vaisman
- Ventura
- Wakasugi
- Walsh
- Wang
- Welsh
- Woynarowski
- Wu
- Zamble
- Zorbas
- Publication venue
- 'Wiley'
- Publication date
- 01/03/2011
- Field of study
Resistance of tumor cells to platinum anticancer agents poses a major problem in cancer chemotherapy. One of the mechanisms associated with platinum-based drug resistance is the enhanced capacity of the cell to carry out nucleotide excision repair (NER) on platinum-damaged DNA. Endonucleases XPF and XPG are critical components of NER, responsible for excising the damaged DNA strand to remove the DNA lesion. Here, we investigated possible consequences of down-regulation of XPF and XPG gene expression in osteosarcoma cancer cells (U2OS) and the impact on cellular transcription and DNA repair. We further evaluated the sensitivity of such cells toward the platinum anticancer drugs cisplatin and oxaliplatin.National Cancer Institute (U.S.) (Grant Number CA034992.)National University of Singapore.German Academic Exchange Service (DAAD
MicroRNA-19b downregulates insulin 1 through targeting transcription factor NeuroD1
- Author
- Publication venue
- Federation of European Biochemical Societies. Published by Elsevier B.V.
- Publication date
- 09/01/1918
- Field of study
AbstractMiR-17-92 cluster miRNAs are disclosed to contribute to the development of multiple organs and tumorigenesis, but their roles in pancreas development remains unclear. In this study, we found that miR-19b, a member of miR-17-92, was highly expressed in the pancreatic progenitor cells, and miR-19b could target the 3′ UTR of NeuroD1 mRNA to decrease its protein and mRNA levels. Functional analysis showed that miR-19b exerted little effect on the proliferation of pancreatic progenitors, whereas it inhibited the expression of insulin 1, but not insulin 2 in MIN6 cells. These results suggest that miR-19b can downregulate insulin 1 expression through targeting transcription factor NeuroD1, and thus regulate the differentiation and function of β-cells
Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
- Author
- Altamirano J
- Arab JP
- Aragon T
- Argemi J
- Atkinson SR
- Avila MA
- Bataller R
- Bell A
- Berasain C
- Blokhin IO
- Caballeria J
- Cabezas J
- Cao S
- Dubuquoy L
- Edmunds LR
- Fondevila C
- Furuya S
- Gomez JL
- Gue JP
- Jurczak MJ
- Lackner C
- Latasa MU
- Louvet A
- Lozano JJ
- Mann J
- Massey V
- Mathurin P
- Monga SP
- Morgan MY
- Odena G
- Rusyn I
- Sancho-Bru P
- Shah VH
- Stärkel P
- Taylor DL
- Thursz MR
- Van Booven D
- Ventura-Cots M
- Vernetti LA
- Wahlestedt C
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 10/02/2023
- Field of study
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
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- Barker A
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- Basegmez S
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- Battilana C
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- Bauer G
- Bauerdick LAT
- Baumgartel D
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- Bayshev I
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- Beaudette F
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- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
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- Belknap D
- Bell AJ
- Bell KW
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- Bellinger JN
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- Belyaev A
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- Bhatnagar V
- Bhattacharya S
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- Bilki B
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- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
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- Bloom K
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- Blumenfeld B
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- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
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- Branca A
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- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
- Brooke JJ
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- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
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- Burgmeier A
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- Calvert B
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- Capiluppi P
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- Cerizza G
- Cerminara G
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chamizo Llatas M
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
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- Chasserat J
- Chatrchyan S
- Chatterjee A
- Chauhan S
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- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cihangir S
- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
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- Clarida W
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- CMS Collaboration
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- Cutajar M
- Cutts D
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- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
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- Dahmes B
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- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
- Davids M
- Davies G
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
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- de Fatis TT
- De Filippis N
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- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
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- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demina R
- Demortier L
- Denegri D
- Deniz M
- Depasse P
- Dermenev A
- Dero V
- Dhingra N
- Di Giovanni GP
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- Prado Da Silva WL
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- Radi A
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- Ranieri R
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- Rappoccio S
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- Redondo I
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- Reyes-Santos MA
- Ribeiro PQ
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- Romeo F
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- Schoefbeck R
- Schoerner-Sadenius T
- Schott G
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- Schwick C
- Scodellaro L
- Scurlock B
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- Segala M
- Segoni I
- Seitz C
- Seixas J
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- Selvaggi G
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- Sen N
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- Sengupta S
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- Seo E
- Seo H
- Serban AT
- Serin M
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- Sexton-Kennedy E
- Sfiligoi I
- Sguazzoni G
- Shah MA
- Sharma A
- Sharma A
- Sharma S
- Sharma V
- Sharma V
- Sharp P
- Sheldon P
- Shepherd-Themistocleous CH
- Shi X
- Shipkowski SP
- Shipsey I
- Shiu JG
- Shivpuri RK
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- Shoaib M
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- Shukla P
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- Sillou D
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- Silverwood H
- Silvestre C
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- Sirois Y
- Siroli G
- Sirunyan AM
- Skhirtladze N
- Skuja A
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- Smirnov I
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- Smolin D
- Snigirev A
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- Soares MS
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- Sudano E
- Sudhakar K
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- Sultanov G
- Summers D
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- Tsang KV
- Tschudi Y
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- Ujvari B
- Ulmer KA
- Ungaro D
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- Uzun D
- Uzunian A
- Vaandering EW
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- Wissing C
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- Womersley WJ
- Won S
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- Wood JS
- Worm SD
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- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
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- Wissing C
- Wittich P
- Wittmer B
- Woehri HK
- Wolf M
- Wolf R
- Womersley WJ
- Won S
- Wood D
- Wood J
- Wood JS
- Worm SD
- Wright D
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- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
- Author
- Abadjiev K
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abelev B
- Acosta D
- Acosta JG
- Acosta MV
- Actis O
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adolphi R
- Adzic P
- Afaq MA
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahmed W
- Ahuja S
- Aisa D
- Aisa S
- Akchurin N
- Akgun B
- Akgun U
- Akimenko S
- Akin IV
- Alagoz E
- Alampi G
- Albajar C
- Albayrak EA
- Alberdi J
- Albergo S
- Albert E
- Albrow M
- Alexander J
- Alidra M
- Aliev T
- Allfrey P
- Almeida N
- Altenhofer G
- Altsybeev I
- Alver B
- Alverson G
- Alves GA
- Amaglobeli N
- Amapane N
- Ambroglini F
- Amsler C
- Anagnostou G
- Ananthan B
- Anastassov A
- Andelin D
- Anderson M
- Andrea J
- Andreev V
- Andreev Y
- Anghel IM
- Anguelov T
- Anh T. Vu
- Anisimov A
- Antillon E
- Antipov P
- Antonelli L
- Anttila E
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arnold B
- Arora S
- Artamonov A
- Asaadi J
- Asghar MI
- Ashby S
- Askew A
- Atac M
- Atramentov O
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- Vogel A.
- Vogel H
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- Volkov S
- Volobouev I
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- Volyanskyy D
- von der Schmitt H.
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- Vorobel V.
- Vorobiev I
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- Worm SD
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- Wraight K.
- Wright C.
- Wright D
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- Wrochna G
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- Wu S
- Wu S. L.
- Wu W
- Wu X.
- Wulf E.
- Wulz CE
- Wurthwein F
- Wynne B. M.
- Wyslouch B
- Xaplanteris L.
- Xella S.
- Xie S
- Xie S.
- Xie Z
- Xu D.
- Xu N.
- Xue Z
- Yagil A
- Yamada M.
- Yamamoto A
- Yan M
- Yang X
- Yang Y
- Yang ZC
- Yarba J
- Yaselli I
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoon AS
- York A
- Yumiceva F
- Yun JC
- Yuste C
- Zabi A
- Zabolotny W
- Zachariadou A
- Zalewski P
- Zampieri A
- Zanetti M
- Zang SL
- Zarubin A
- Zatzerklyany A
- Zeidler C
- Zeinali M
- Zeise M
- Zelepoukine S
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang L
- Zhang Y
- Zhang Z
- Zheng Y
- Zhiltsov V
- Zhokin A
- Zhu B
- Zhu K
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Zielinski M
- Zilizi G
- Zinonos Z
- Zito G
- Zoeller MH
- Zotto P
- Zub S
- Zumerle G
- Zuranski A
- Zuyeuski R
- Zych P
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
Search for direct stau production in events with two hadronic tau-leptons in root s=13 TeV pp collisions with the ATLAS detector
- Author
- A. Abed Abud
- A. Adiguzel
- A. Aggarwal
- A. Alfonsi
- A. Aloisio
- A. Alonso
- A. Ambler
- A. Andreazza
- A. Angerami
- A. Annovi
- A. Armstrong
- A. Artamonov
- A. Bandyopadhyay
- A. Baroncelli
- A. Basalaev
- A. Bassalat
- A. Beddall
- A. Behera
- A. Bellerive
- A. Bethani
- A. Betti
- A. Bingul
- A. Bitadze
- A. Blue
- A. Bocci
- A. Borisov
- A. Boveia
- A. Bruni
- A. Buzatu
- A. Calandri
- A. Camplani
- A. Campoverde
- A. Canesse
- A. Catinaccio
- A. Cattai
- A. Cerri
- A. Cervelli
- A. Cheplakov
- A. Chitan
- A. Ciocio
- A. Clark
- A. Coccaro
- A. Cortes-Gonzalez
- A. Cueto
- A. D’
- A. Dattagupta
- A. De Maria
- A. De Salvo
- A. De Santo
- A. Dell’
- A. Dewhurst
- A. Di Ciaccio
- A. Di Girolamo
- A. Dimitrievska
- A. Doria
- A. Dubreuil
- A. Ducourthial
- A. Dudarev
- A. Duperrin
- A. Durglishvili
- A. Emerman
- A. Ereditato
- A. Ezhilov
- A. Farbin
- A. Farilla
- A. Fell
- A. Ferrante
- A. Ferrari
- A. Ferrer
- A. Filipč
- A. Formica
- A. Gabrielli
- A. Gabrielli
- A. Gaudiello
- A. Gavrilyuk
- A. Ghosh
- A. Ghosh
- A. Giannini
- A. Glazov
- A. Gomes
- A. Gongadze
- A. Goriš
- A. Grummer
- A. Guerguichon
- A. Hö
- A. Haas
- A. Hadef
- A. Hasib
- A. Held
- A. Higashida
- A. Hoecker
- A. Hoummada
- A. Hrynevich
- A. Ivina
- A. Jelinskas
- A. Jinaru
- A. Juste Rozas
- A. Kaczmarska
- A. Kaluza
- A. Kamenshchikov
- A. Kastanas
- A. Khanov
- A. Khodinov
- A. Klimentov
- A. Knue
- A. Korn
- A. Kotwal
- A. Koulouris
- A. Kourkoumeli-Charalampidi
- A. Krasznahorkay
- A. Krishnan
- A. Kugel
- A. Kupco
- A. Kurova
- A. Lö
- A. La Rosa
- A. Lanza
- A. Lapertosa
- A. Laudrain
- A. Laurier
- A. Leisos
- A. Leopold
- A. Liblong
- A. Lipniacka
- A. Lister
- A. Lleres
- A. Lopez Solis
- A. Lounis
- A. Lucotte
- A. Macchiolo
- A. Maio
- A. Mann
- A. Manousos
- A. Marantis
- A. Marzin
- A. Mastroberardino
- A. Matic
- A. Mehta
- A. Melzer
- A. Messina
- A. Milic
- A. Milov
- A. Mirto
- A. Miucci
- A. Mizukami
- A. Montalbano
- A. Murrone
- A. Negri
- A. Nisati
- A. Ochi
- A. Ogrodnik
- A. Oh
- A. Olariu
- A. Olszewski
- A. Onofre
- A. Ouraou
- A. Pacheco Pages
- A. Paramonov
- A. Pathak
- A. Petridis
- A. Peyaud
- A. Picazio
- A. Poley
- A. Policicchio
- A. Polini
- A. Puri
- A. Quadt
- A. Qureshi
- A. Ramirez Morales
- A. Redelbach
- A. Reiss
- A. Rej
- A. Rimoldi
- A. Robson
- A. Rocchi
- A. Rodriguez Perez
- A. Romaniouk
- A. Roy
- A. Rozanov
- A. Ruiz-Martinez
- A. Rummler
- A. Ryzhov
- A. Sø
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- A. Sydorenko
- A. Taffard
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- A. Tavares Delgado
- A. Traeet
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- A. Trzupek
- A. Tsirigotis
- A. Tudorache
- A. Undrus
- A. Vaidya
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- A. Vaniachine
- A. Ventura
- A. Verbytskyi
- A. Vishwakarma
- A. Warburton
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- A.N. Nag
- B. Abbott
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- B. Burghgrave
- B. Chargeishvili
- B. Chen
- B. Cole
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- B. Liu
- B. Lund-Jensen
- B. Mač
- B. Malaescu
- B. Mansoulie
- B. Martin dit Latour
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- B. Mindur
- B. Moser
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- B. Parida
- B. Pearson
- B. Ravina
- B. Safarzadeh Samani
- B. Stanislaus
- B. Stapf
- B. Stelzer
- B. Stugu
- B. Tong
- B. Trocmé
- B. Vachon
- B. Yabsley
- B. Zabinski
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- C. Adam Bourdarios
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- C. Anastopoulos
- C. Antel
- C. Arcangeletti
- C. Bakalis
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- C. Blocker
- C. Bohm
- C. Camincher
- C. Chen
- C. Clement
- C. Dü
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- C. David
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- C. Wang
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- D. Á
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- D. Camarero Munoz
- D. Cameron
- D. Chakraborty
- D. Cieri
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- D. Costanzo
- D. De Pedis
- D. Delgove
- D. Della Volpe
- D. Denysiuk
- D. Derendarz
- D. Di Valentino
- D. Dodsworth
- D. Duda
- D. Duschinger
- D. Duvnjak
- D. Emeliyanov
- D. Fassouliotis
- D. Ferrere
- D. Fournier
- D. Francis
- D. Froidevaux
- D. Gillberg
- D. Giugni
- D. Godin
- D. Golubkov
- D. Goujdami
- D. Guest
- D. Hayden
- D. Hirschbuehl
- D. Hohn
- D. Hohov
- D. Iliadis
- D. Kar
- D. Kelsey
- D. Kirchmeier
- D. Kobayashi
- D. Krasnopevtsev
- D. Krauss
- D. Lacour
- D. Lellouch
- D. Levin
- D. Lynn
- D. Madaffari
- D. Malon
- D. Matakias
- D. Melini
- D. Moreno
- D. Mori
- D. Muenstermann
- D. Oliveira Damazio
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- F. Becherer
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- F. Ceradini
- F. Cerutti
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- P. Gkountoumis
- P. Grenier
- P. Gutierrez
- P. Hamal
- P. Horn
- P. Huo
- P. Iengo
- P. Jacka
- P. Jackson
- P. Jenni
- P. Johansson
- P. Klimek
- P. Kluit
- P. Kodys
- P. Krieger
- P. Liu
- P. Loch
- P. Mä
- P. Malecki
- P. Massarotti
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- S. Bethke
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- S. Cabrera Urbá
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- S. Camarda
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- S. Menke
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- S. Pagan Griso
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- S. Pataraia
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- S. Prince
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- S.-. Hsu
- T. Š
- T. Ž
- T. Adye
- T. Alexopoulos
- T. Andeen
- T. Barillari
- T. Barklow
- T. Beau
- T. Berry
- T. Bisanz
- T. Blazek
- T. Bold
- T. Buanes
- T. Cao
- T. Carli
- T. Cuhadar Donszelmann
- T. Dado
- T. Dai
- T. Daubney
- T. Davidek
- T. Dias Do Vale
- T. Djobava
- T. Dreyer
- T. Eifert
- T. Ekelof
- T. Farooque
- T. Flick
- T. Fusayasu
- T. Geralis
- T. Golling
- T. Guillemin
- T. Harenberg
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- T. Herrmann
- T. Hryn’
- T. Iizawa
- T. Jakoubek
- T. Javů
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- T. Kawamoto
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- T. Klapdor-Kleingrothaus
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- T. Lenz
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- T. Maeno
- T. Maier
- T. Mashimo
- T. Masubuchi
- T. Megy
- T. Meideck
- T. Mitani
- T. Mkrtchyan
- T. Moa
- T. Moskalets
- T. Nakamura
- T. Naumann
- T. Nguyen Manh
- T. Nitta
- T. Nobe
- T. Novak
- T. Okuyama
- T. Pauly
- T. Peiffer
- T. Pham
- T. Poulsen
- T. Rashid
- T. Saito
- T. Scanlon
- T. Seiss
- T. Sumida
- T. Swirski
- T. Sykora
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- T. Theveneaux-Pelzer
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- U. Blumenschein
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- U. Soldevila
- V. Andrei
- V. Araujo Ferraz
- V. Bü
- V. Boisvert
- V. Canale
- V. Castillo Gimenez
- V. Cavaliere
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- V. Chiarella
- V. Cindro
- V. Croft
- V. D’
- V. Dao
- V. Ellajosyula
- V. Fabiani
- V. Garonne
- V. Gratchev
- V. Hedberg
- V. Herget
- V. Ippolito
- V. Izzo
- V. Jain
- V. Kartvelishvili
- V. Kitali
- V. Konstantinides
- V. Kouskoura
- V. Kukhtin
- V. Lyubushkin
- V. Magerl
- V. Morisbak
- V. Nikolaenko
- V. O’
- V. Pleskot
- V. Polychronakos
- V. Sinetckii
- V. Smakhtin
- V. Solovyev
- V. Tsiskaridze
- V. Tsulaia
- V. Tudorache
- V. Vacek
- V. Vecchio
- V. Vercesi
- V. Vorobel
- V. Vrba
- V. Wallangen
- V. Zhulanov
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- W. Dabrowski
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- W. Fedorko
- W. Guan
- W. Guo
- W. Islam
- W. Kozanecki
- W. Lampl
- W. Song
- W. Taylor
- W. Trischuk
- W. Vandelli
- W. Verkerke
- W. Wagner
- W. Walkowiak
- W. Wang
- W. Wiedenmann
- W. Xu
- W. Yao
- W. 
- W. 
- W. 
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- W. 
- W. 
- W. 
- W. 
- W. 
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- W. 
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- W. 
- X. Ai
- X. Chen
- X. Chu
- X. Hoad
- X. Ju
- X. Li
- X. Lou
- X. Lou
- X. Ruan
- X. Sun
- X. Wu
- X. Xiao
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- X. 
- Y. Abulaiti
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- Y. Duan
- Y. Enari
- Y. Fang
- Y. Fang
- Y. Gao
- Y. Guo
- Y. Hasegawa
- Y. Heng
- Y. Herná
- Y. Horii
- Y. Huang
- Y. Huang
- Y. Ikegami
- Y. Jiang
- Y. Kano
- Y. Kulchitsky
- Y. Li
- Y. Liu
- Y. Ma
- Y. Makida
- Y. Minegishi
- Y. Nagasaka
- Y. Nakahama
- Y. Ninomiya
- Y. Noguchi
- Y. Okazaki
- Y. Okumura
- Y. Qin
- Y. Rozen
- Y. Sano
- Y. Shen
- Y. Shimogama
- Y. Smirnov
- Y. Takubo
- Y. Tayalati
- Y. Tian
- Y. Tu
- Y. Unno
- Y. Wang
- Y. Wu
- Y. Yamaguchi
- Y. Yamazaki
- Y. Yang
- Y. Yasu
- Y. Zhang
- Y. Zhao
- Y. Zhou
- Y. Zhu
- Y. 
- Y. 
- Y. 
- Y. 
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- Y. 
- Y. 
- Y. 
- Y. 
- Z. Barnovska-Blenessy
- Z. Chadi
- Z. Dolezal
- Z. Guo
- Z. Hubacek
- Z. Idrissi
- Z. Jiang
- Z. Li
- Z. Liang
- Z. Marshall
- Z. Rurikova
- Z. Uysal
- Z. Wang
- Z. Xi
- Z. Xu
- Z. Xu
- Z. Yan
- Z. Zhang
- Z. Zhang
- Z. Zhao
- Z. Zheng
- Z. Zinonos
- Z. 
- Z. 
- Z. 
- Z. 
- Z. 
- Z. 
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2020
- Field of study
A search for the direct production of the supersymmetric partners ofτ-leptons (staus) in final stateswith two hadronically decayingτ-leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of139fb−1, recorded with the ATLAS detector at the LargeHadron Collider at a center-of-mass energy of 13 TeV. No significant deviation from the expected StandardModel background is observed. Limits are derived in scenarios of direct production of stau pairs with eachstau decaying into the stable lightest neutralino and oneτ-lepton in simplified models where the two staumass eigenstates are degenerate. Stau masses from 120 GeV to 390 GeV are excluded at 95% confidencelevel for a massless lightest neutralino
Cytogenetic analysis of Astylus antis (Perty, 1830) (Coleoptera, Melyridae): Karyotype, heterochromatin and location of ribosomal genes
- Author
- Almeida MC
- Bione E
- Carlos Campaner
- Colomba M
- Colomba M
- Colomba MS
- Colomba MS
- Comings DE
- Comings DE
- Costa C
- Costa C
- Drets ME
- Ernani de Oliveira Mendes-Neto
- Gillot C
- Howell WM
- Johnston FP
- Juan C
- Juan C
- Juan C
- Lawrence JF
- Levan A
- Maffei EMD
- Maffei EMD
- Mara Cristina Almeida
- Marcelo Ricardo Vicari
- Moura RC
- Petitpierre E
- Pinkel D
- Plohl M
- Postiglioni A
- Postiglioni A
- Roberto Ferreira Artoni
- Rosseto CJ
- Rozek M
- Saitoh Y
- Schneider MC
- Schneider MC
- Schweizer D
- Smith SG
- Smith SG
- Smith SG
- Souza B
- Sumner AT
- Ventura MU
- Vicari MR
- Virkki N
- Virkki N
- Virkki N
- Virkki N
- Virkki N
- Vitturi R
- Viviane Nogaroto
- Weber F
- Yadav JS
- Yadav JS
- Zimmer CH
- Publication venue
- Sociedade Brasileira de Genética
- Publication date
- 01/01/2010
- Field of study
Cytogenetic analysis of Astylus antis using mitotic and meiotic cells was performed to characterize the haploid and diploid numbers, sex determination system, chromosome morphology, constitutive heterochromatin distribution pattern and chromosomes carrying nucleolus organizer regions (NORs). Analysis of spermatogonial metaphase cells revealed the diploid number 2n = 18, with mostly metacentric chromosomes. Metaphase I cells exhibited 2n = 8II+Xyp and a parachute configuration of the sex chromosomes. Spermatogonial metaphase cells submitted to C-banding showed the presence of small dots of constitutive heterochromatin in the centromeric regions of nearly all the autosomes and on the short arm of the X chromosome (Xp), as well as an additional band on one of the arms of pair 1. Mitotic cells submitted to double staining with base-specific fluorochromes (DAPI-CMA3 ) revealed no regions rich in A+T or G+C sequences. Analysis of spermatogonial mitotic cells after sequential Giemsa/AgNO 3 staining did not reveal any specific mark on the chromosomes. Meiotic metaphase I cells stained with silver nitrate revealed a strong impregnation associated to the sex chromosomes, and in situ hybridization with an 18S rDNA probe showed ribosomal cistrons in an autosomal bivalent
Mortality of Oryzophagus oryzae (Costa Lima, 1936) (Coleoptera: Curculionidae) and Spodoptera frugiperda (J E Smith, 1797) (Lepidoptera: Noctuidae) Larvae Exposed to Bacillus thuringiensis and Extracts of Melia azedarach
- Author
- Abbott WS
- Alessandra Sebben
- Aline Oliboni de Azambuja
- Barreto MR
- Ben-Dov E
- Bhalla R
- Bohnenstengel FI
- Bradford MM
- Breuer M
- Brunhetto R
- Carpinella MC
- Cesconetto AO
- Charleston DS
- Crickmore N
- De-Barjac H
- De-Maagd Ra
- De-Maagd RA
- Diouneia Lisiane Berlitz
- Fiuza LM
- Haddad ML
- Hansen BM
- Heckel D
- Huang RC
- Höfte H
- Jaime Vargas de Oliveira
- Laemmli U
- Lidia Mariana Fiuza
- Marquez BP
- Martins JFS
- Nathan SS
- Pinto LMN
- Poitout S
- Polanczyk RA
- Sabbour MM
- Santolamazza-Carbone S
- Schnepf E
- Silva SMB
- Uribe D
- Ventura MU
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Extracellular Sulfatases, Elements of the Wnt Signaling Pathway, Positively Regulate Growth and Tumorigenicity of Human Pancreatic Cancer Cells
- Author
- A Bafico
- A Bhattacharjee
- A Grigoriadis
- A Marcao
- A Ventura
- AI Su
- AM Lowy
- Annemieke van Zante
- B He
- BL Viviano
- CA Iacobuzio-Donahue
- CM Alexander
- D Laheru
- DH Lum
- DM Berman
- G Zeng
- GK Dhoot
- J Kreuger
- J Lai
- J Li
- J Mazieres
- JD Esko
- JP Lai
- JP Lai
- JP Lai
- JT Gallagher
- K Narita
- K Uchimura
- L You
- LM Galli
- M Morimoto-Tomita
- M Morimoto-Tomita
- M Pasca di Magliano
- M Wiznerowicz
- Matthias Hebrok
- MI Capurro
- Michael McManus
- Mikhail Blagosklonny
- MU Morimoto-Tomita
- PW Derksen
- R Nusse
- Roman Nawroth
- RS Heller
- S Chada
- Sara Cervantes
- SP Thayer
- SR Hingorani
- Steven D. Rosen
- T Ohto
- T Reya
- WC Lamanna
- X Ai
- X Ai
- X Lin
- Y Dai
- Y Kakinuma
- Y Kawano
- Publication venue
- Public Library of Science
- Publication date
- 01/04/2007
- Field of study
BACKGROUND: Heparan sulfate proteoglycans (HSPGs) are control elements in Wnt signaling, which bind extracellularly to Wnt ligands and regulate their ability to interact with signal transduction receptors on the cell surface. Sulf-1 and Sulf-2 are novel extracellular sulfatases that act on internal glucosamine-6-sulfate (6S) modifications within HSPGs and thereby modulate HSPG interactions with various signaling molecules, including Wnt ligands. Emerging evidence indicates the importance of reactivated Wnt signaling in a number of cancers, including pancreatic adenocarcinoma. PRINCIPLE FINDINGS: Both Sulf proteins were upregulated in human pancreatic adenocarcinoma tumors and were broadly expressed in human pancreatic adenocarcinoma cell lines. Expression of human extracellular sulfatases Sulf-1 and Sulf-2 enhanced Wnt signaling in a reconstituted system. Three of four pancreatic adenocarcinoma cell lines tested exhibited autocrine Wnt signaling, in that extracellular Wnt ligands were required to initiate downstream Wnt signaling. Exposure of these pancreatic adenocarcinoma cells to a catalytically inactive form of Sulf-2 or siRNA-mediated silencing of endogenous Sulf-2 inhibited both Wnt signaling and cell growth. Sulf-2 silencing in two of these lines resulted in markedly reduced tumorigenesis in immunocompromised mice. CONCLUSIONS/SIGNIFICANCE: We have identified the Sulfs as potentiators of autocrine Wnt signaling in pancreatic cancer cells and have demonstrated their contribution to the growth and tumorigenicity of these cells. Since the Sulfs are extracellular enzymes, they would be attractive targets for therapy of pancreatic cancer. Our results run counter to the prevailing view in the literature that the Sulfs are negative regulators of tumorigenesis
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