New Synthesis of (±)-Cherylline and Mono- and Dimethyl Ethers

<div><p></p><p>The synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines is achieved via the ether rearrangement methodology. Subsequent reactions yielded cherylline and ether derivatives of amaryllidaceac alkaloids.</p> </div

Total Synthesis of an Experimental Antitubercular Drug CDRI-830

<div><p></p><p>The triarylmethane antituberculosis drug CDRI-830 is synthesized. The triarylmethane derivative <b>4</b> is prepared from ether <b>6</b> by a rearrangement process. The total synthesis of the drug CDRI-830 is achieved in a good overall yield of 35% from a simple thiophene derivative <b>8</b>.</p> </div