Perfil de saúde de óbitos por sepse em Goiás

Introdução: A Síndrome da Resposta Inflamatória Sistêmica (SIRS), também é conhecida como sepse. Desde 2016, é definida como disfunção orgânica com risco de vida causada por uma resposta desregulada do hospedeiro à infecção. No Brasil, representa de 30 a 60% dos óbitos em Unidade de Terapia Intensiva (UTI), o que é um problema grave de saúde pública. Objetivo: Avaliar atualizações na literatura e realizar busca no Departamento de Informática do Sistema Único de Saúde (DATASUS) sobre sepse em Goiás. Método: Trata-se de um estudo longitudinal para o ano de 2019 no DATASUS. As variáveis selecionadas no banco de dados foram: “Mortalidade – dede 1996 pela CID-10”, “Mortalidade geral”, “Goiás”, “Mortalidade – Goiás; Linha: Região de Saúde (CIR); Coluna: Capítulo CID-10; Conteúdo: Óbitos por Residência”, “Períodos Disponíveis: 2019”, “Seleções Disponíveis: Categoria CID-10: 041 Outras septicemias”. O estudo associa revisão da literatura com coleta em bancos de dados reconhecidos pela comunidade científica, tais como: PubMed, CAPES e The Lancet, no período de 2017-2021, versando seu conteúdo em língua vernácula, inglesa e espanhola. Resultado: Foram identificados 242 casos de Sepse em Goiás no ano de 2019, sendo este um problema de saúde pública. Observou-se que o DATASUS ainda utiliza a nomenclatura septicemia, atualmente obsoleta. Conclusão: O resultado obtido é indicativo de uma grave situação de saúde coletiva, quando se considera as inúmeras UTIs em Goiás, o que sugere um melhor planejamento das equipes de saúde, a fim de mitigar os impactos da sepse, o que é preditivo de redução de óbitos relacionados à Sepse

Arquitetura residencial verticalizada em São Paulo nas décadas de 1930 e 1940

O presente trabalho aborda o tema, ainda pouco estudado, da arquitetura residencial verticalizada em São Paulo, nas décadas de 1930 e 1940. A partir de alguns estudos de caso representativos, são apresentadas observações relativas a aspectos como: as estratégias de disseminação da nova forma de morar; as opções estéticas disponíveis; a definição dos programas das unidades e as soluções de planta desenvolvidas. Espera-se evidenciar a riqueza e complexidade do assunto, que se configura não apenas como importante tema da história da arquitetura paulistana, mas, principalmente, como significativo patrimônio cultural da cidade, a ser conhecido e protegido.The present work addresses the topic, as yet scarcely studied, of high-rise residential architecture in Sao Paulo during the 1940s and 50s. Supported by some representative case studies, observations were drawn on the following aspects: the strategies used to propagate this new dwelling form, the available aesthetical options for these buildings, the definition of these units' purposes and uses and the development of ground plan architectural solutions. This article aims to render evident the great value and complexity of its subject matter, which is not only extremely important as a theme of Sao Paulo's architectural history, but also, and foremostly, as a significant cultural heritage of this city, which should be acknowledged and safeguarded

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Susceptibility of Triatoma sordida Stal, 1859 (Hemiptera: Reduviidae) to alpha-cypermethrin under natural climatic conditions

Abstract:INTRODUCTION:Despite the recommendations by interpretation of resistance ratios obtained in laboratory bioassays, little is known about the actual impact of these results in the effectiveness of vector control activities in the field. In this context, our objective was to determine the mean value of different resistance ratios obtained by laboratory bioassays performed as part of the chemical control strategies of Triatoma sordida in the field.METHODS:Field bioassays were developed in Monte Azul and Coração de Jesus (Southeast, Brazil). In each location, samples were formed with three domestic units treated with alpha-cypermethrin 20.0% (Alfatek (r) 200 SC). One day after spraying, 10 fifth-instar nymphs remained in contact with the surfaces treated (adobe with plaster, adobe without plaster, or wood) with insecticide in plastic cones for 72h. Three cones were exposed inside the intradomicile and the peridomicile. The insects in the control group were exposed to an insecticide-free piece of cardboard. Mortality was measured 72h after removal of the insects from the treated surfaces. The tests were realized in triplicate.RESULTS:Mortality was 100.0% in all locations, except for Monte Azul; Landinho (96.6%) and Coração de Jesus; Barriguda (96.6%).CONCLUSIONS:Although the resistant populations in laboratory tests proved to be susceptible in the field, this observation is not sufficient to suggest that the cut-off points used to justify the resistance ratio should be changed. In this sense, we recommend that laboratory and field bioassays are carried out with a greater number of Triatominae populations to allow more in-depth consideration of the subject

Deformation of nickel-titanium closed coil springs: an in vitro study

ABSTRACT Objective: The aim of this paper was to determine the amount of deformation in four commercial brands of nickel-titanium closed springs. Methods: A total of 130 springs were divided into 13 subgroups, according to their features and manufacturers (Morelli, Orthometric, Ormco and GAC) and activated from 100% to 1000% of the effective length of the nickel-titanium portion present at the spring, at 37 °C. Deactivation data were plotted and deformation was found graphically. The values were compared by analysis of variance and Tukey's post-hoc test. Results: Springs manufactured by Morelli had the same amount of deformation when they were activated up to 700% of Y activation; springs by Orthometric had the same amount of deformation up to 600-700% of Y; springs by Ormco had the same amount of deformation up to 700-800% of Y; and finally, the majority of springs by GAC had similar deformation up to 800%-1000% of activation. All springs tested could be activated up to 700% without rupture. Conclusions: Most subgroups were similarly deformed up to 700% of activation, without rupture of springs. Subgroups 4B, 4C, 4D and 4E showed the same amount of deformation up to 1000% of activation without any rupture at all

Effect of 2% chlorhexidine on microtensile bond strength of composite to dentin

Purpose: To evaluate the effect of 2% chlorhexidine on the microtensile bond strength of composite resin to dentin treated with three dentin bonding systems. Materials and Methods: Flat dentinal surfaces were prepared in 24 extracted human third molars. Teeth were randomly divided into 8 distinct experimental groups according to the adhesive applied (Prime & Bond NT, Single Bond and Clearfil SE Bond), the application (yes/no) of chlorhexidine, and the time point at which it was applied (before or after acid etching the dentin). Composite resin blocks were built up over treated surfaces, and teeth were then stored in water at 37°C for 24 h. Samples were thermocycled, stored under the same conditions, and then vertically sectioned, thus obtaining specimens with 1.0 ± 0.1 mm2 cross-sectional area. Specimens were stressed in tension at 0.5 mm/min crosshead speed. Bond strength results were evaluated using a one-way ANOVA (p < 0.05). The modes of failures were verified using optical microscopy. Dentin disks were obtained from 3 additional teeth treated in the same manner for observation under SEM. The most representative samples of fractured specimens were also observed under SEM. Results: No statistically significant differences of bond strength values were found between any groups. Failures occurred mainly within the bond; exclusively adhesive fractures (adhesive-dentin) were not observed. Conclusion: The 2% chlorhexidine solution, applied before or after acid etching of the dentin, did not interfere with the microtensile bond strength of composite resin to the dentin treated with Prime & Bond NT, Single Bond, or Clearfil SE Bond bonding systems