Plans for State Diagnostic Laboratory

Everyone here at the Iowa State College, Division of Veterinary Medicine is anxiously watching the construction progress of the new Iowa State Veterinary Medical Diagnostic Laboratory. After much effort on the part of the administrative staff, faculty, architects and many others, they are finally seeing their dream come true as workmen pour the concrete for the ground floor here this spring. This step forward was made possible when the 55th General Assembly met in 1953 and appropriated $600,000 for the construction of a new laboratory. This allocation is to also facilitate the remodeling of the present buildings housing the Departments of Anatomy, Pathology and Hygiene

Emerging Definitions of Leadership in Higher Education

The higher education literature suggests that alternative leadership styles are replacing the traditionally held definitions of leadership and provide new and different (and possibly superior) ways to understand leadership. This article looks for parallels within the current leadership literature to see if community college administrators use the alternative language or emerging definitions of leadership to self-describe their own leadership or if their self-descriptions fit the more traditional hierarchical ideal of the positional or hero leader

Probabilistic computer model of optimal runway turnoffs

Landing delays are currently a problem at major air carrier airports and many forecasters agree that airport congestion will get worse by the end of the century. It is anticipated that some types of delays can be reduced by an efficient optimal runway exist system allowing increased approach volumes necessary at congested airports. A computerized Probabilistic Runway Turnoff Model which locates exits and defines path geometry for a selected maximum occupancy time appropriate for each TERPS aircraft category is defined. The model includes an algorithm for lateral ride comfort limits

Tests at 2K of the beta 0.35 spoke cryomodule prototype with the MTCA.4-based Low Level RF system prototype for the MYRRHA R&D

Within the framework of the first phase of MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) project, called MINERVA, IJCLab was in charge of a fully equipped Spoke cryomodule prototype development, tested at 2K. It integrates two superconducting single spoke cavities, the RF power couplers and the Cold Tuning Systems associated. On the control side, a MTCA.4-based Low Level Radio Frequency (LLRF) system prototype and the Software/EPICS developments has been realized by IJCLab and the SCK CEN in collaboration with the company IOxOS Technologies. The final version of the global system and the results of the tests at 2K will show with some perspectives.Comment: Poster pr\'esent\'e au LLRF Workshop 2023 (LLRF2023, arXiv : 2310.03199

Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease

Early Alzheimer’s disease (AD) is associated with hippocampal hyperactivity and decreased sleep quality. Here we show that homeostatic mechanisms transiently counteract the increased excitatory drive to CA1 neurons in App NL-G-F mice, but that this mechanism fails in older mice. Spatial transcriptomics analysis identifies Pmch as part of the adaptive response in App NL-G-F mice. Pmch encodes melanin-concentrating hormone (MCH), which is produced in sleep–active lateral hypothalamic neurons that project to CA1 and modulate memory. We show that MCH downregulates synaptic transmission, modulates firing rate homeostasis in hippocampal neurons and reverses the increased excitatory drive to CA1 neurons in App NL-G-F mice. App NL-G-F mice spend less time in rapid eye movement (REM) sleep. App NL-G-F mice and individuals with AD show progressive changes in morphology of CA1-projecting MCH axons. Our findings identify the MCH system as vulnerable in early AD and suggest that impaired MCH-system function contributes to aberrant excitatory drive and sleep defects, which can compromise hippocampus-dependent functions

Farmers review of Best Management Practices: drivers and barriers as seen by adopters and non-adopters

Assessing farmers’ intention to adopt best management practices across eight European countrie