16 research outputs found
Factors Associated with Height Catch-Up and Catch-Down Growth Among Schoolchildren
In developed countries, children with intrauterine growth restriction (IUGR) or born preterm (PT) tend to achieve catch-up growth. There is little information about height catch-up in developing countries and about height catch-down in both developed and developing countries. We studied the effect of IUGR and PT birth on height catch-up and catch-down growth of children from two cohorts of liveborn singletons. Data from 1,463 children was collected at birth and at school age in Ribeirão Preto (RP), a more developed city, and in São LuÃs (SL), a less developed city. A change in z-score between schoolchild height z-score and birth length z-score≥0.67 was considered catch-up; a change in z-score≤−0.67 indicated catch-down growth. The explanatory variables were: appropriate weight for gestational age/PT birth in four categories: term children without IUGR (normal), IUGR only (term with IUGR), PT only (preterm without IUGR) and preterm with IUGR; infant's sex; maternal parity, age, schooling and marital status; occupation of family head; family income and neonatal ponderal index (PI). The risk ratio for catch-up and catch-down was estimated by multinomial logistic regression for each city. In RP, preterms without IUGR (RR = 4.13) and thin children (PI<10th percentile, RR = 14.39) had a higher risk of catch-down; catch-up was higher among terms with IUGR (RR = 5.53), preterms with IUGR (RR = 5.36) and children born to primiparous mothers (RR = 1.83). In SL, catch-down was higher among preterms without IUGR (RR = 5.19), girls (RR = 1.52) and children from low-income families (RR = 2.74); the lowest risk of catch-down (RR = 0.27) and the highest risk of catch-up (RR = 3.77) were observed among terms with IUGR. In both cities, terms with IUGR presented height catch-up growth whereas preterms with IUGR only had height catch-up growth in the more affluent setting. Preterms without IUGR presented height catch-down growth, suggesting that a better socioeconomic situation facilitates height catch-up and prevents height catch-down growth
Prevalence of non-communicable diseases in Brazilian children: follow-up at school age of two Brazilian birth cohorts of the 1990's
<p>Abstract</p> <p>Background</p> <p>Few cohort studies have been conducted in low and middle-income countries to investigate non-communicable diseases among school-aged children. This article aims to describe the methodology of two birth cohorts, started in 1994 in Ribeirão Preto (RP), a more developed city, and in 1997/98 in São LuÃs (SL), a less developed town.</p> <p>Methods</p> <p>Prevalences of some non-communicable diseases during the first follow-up of these cohorts were estimated and compared. Data on singleton live births were obtained at birth (2858 in RP and 2443 in SL). The follow-up at school age was conducted in RP in 2004/05, when the children were 9-11 years old and in SL in 2005/06, when the children were 7-9 years old. Follow-up rates were 68.7% in RP (790 included) and 72.7% in SL (673 participants). The groups of low (<2500 g) and high (≥ 4250 g) birthweight were oversampled and estimates were corrected by weighting.</p> <p>Results</p> <p>In the more developed city there was a higher percentage of non-nutritive sucking habits (69.1% vs 47.9%), lifetime bottle use (89.6% vs 68.3%), higher prevalence of primary headache in the last 15 days (27.9% vs 13.0%), higher positive skin tests for allergens (44.3% vs 25.3%) and higher prevalence of overweight (18.2% vs 3.6%), obesity (9.5% vs 1.8%) and hypertension (10.9% vs 4.6%). In the less developed city there was a larger percentage of children with below average cognitive function (28.9% vs 12.2%), mental health problems (47.4% vs 38.4%), depression (21.6% vs 6.0%) and underweight (5.8% vs 3.6%). There was no difference in the prevalence of bruxism, recurrent abdominal pain, asthma and bronchial hyperresponsiveness between cities.</p> <p>Conclusions</p> <p>Some non-communicable diseases were highly prevalent, especially in the more developed city. Some high rates suggest that the burden of non-communicable diseases will be high in the future, especially mental health problems.</p
Frequency (weighted percentage) and non-adjusted risk ratio for the change in height z-score (catch-up and catch-down growth) according to birth variables. Ribeirão Preto, 1994/2004–05.
*<p>RR- risk ratio;</p>**<p>CI – confidence interval;</p>***<p>normal: term children without IUGR – intrauterine growth restriction;</p>****<p>p value excluding missing data and calculated by the chi-square test.</p
Initial sample, eligible for follow-up, number and percentage followed-up in the 1994 Ribeirão Preto and 1997/98 São LuÃs birth cohorts.
*<p>P value calculated by the chi-square test.</p
Mean z-score for birth length and for height at school age and difference between these means by preterm birth/IUGR status. Ribeirão Preto, 1994/2004–05 and São LuÃs, 1997–98/2005–06.
*<p>difference between birth length z-score and height at school age;</p>**<p>CI – confidence interval;</p>***<p>normal: term children without IUGR – intrauterine growth restriction;</p>****<p>Calculated by ANOVA.</p
Adjusted risk ratio for the changes in z-score for height (catch-up and catch-down growth) according to birth variables. São LuÃs, 1997–98/2005–06.
*<p>RR- risk ratio;</p>**<p>CI – confidence interval;</p>***<p>normal: term children without IUGR – intrauterine growth restriction;</p
Staff workload and adverse events during mechanical ventilation in neonatal intensive care units
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Previous issue date: 2011Universidade Federal do Maranhão. Departamento de Medicina III. São LuÃs, MA, Brasil.Universidade Federal do Maranhão. Departamento de Saúde Pública. São LuÃs, MA, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Neonatologia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Maranhão. Departamento de Saúde Pública. São LuÃs, MA, Brasil.Universidade Federal do Maranhão. Departamento de Medicina I. São LuÃs, MA, Brasil.Universidade Federal do Maranhão. Departamento de Saúde Pública. São LuÃs, MA, Brasil.Objetivo: Investigar uma possÃvel associação entre a carga de tra-balho de profissionais da saúde e eventos adversos intermediários, tais
como extubação acidental, obstrução do tubo endotraqueal e desconexão
acidental do circuito do ventilador, durante ventilação mecânica neonatal
em unidades neonatais de alto risco.
Método: Este estudo de coorte prospectiva analisou os dados refe-rentes a 543 recém-nascidos de unidades de terapia intensiva neonatal
(UTINs) de São LuÃs (MA) por 6 meses, durante os quais 136 recém-nascidos foram submetidos a ventilação mecânica em 1.108 turnos e
foram observados 4.554 vezes.
Resultados:Ocorreram eventos adversos 117 vezes durante esse
perÃodo. As associações entre carga de trabalho e eventos adversos foram
analisadas por meio de equações de estimação generalizada. As variáveis
de ajuste foram: peso de nascimento, gênero, maternidade estudada,
pontuação no Ãndice de risco clÃnico para bebês (clinical risk index for
babies) e demanda de cuidados, determinada pela escala desenvolvida
pela Northern Neonatal Network. Quanto maior o número de recém-nas-cidos classificados de acordo com a demanda de cuidados (RCDCs) por
enfermeiro e técnico em enfermagem, maior a probabilidade da ocorrência
de eventos adversos intermediários relacionados à ventilação mecânica.
Um número de RCDCs > 22 por enfermeiro [risco relativo (RR) = 2,86]
e > 4,8 por enfermeiro auxiliar (RR = 3,41) esteve associado a uma
maior prevalência de eventos adversos intermediários.
Conclusões: A carga de trabalho dos profissionais de UTINs parece
interferir nos resultados intermediários do cuidado neonatal e, portanto,
deve ser levada em conta na avaliação dos desfechos na UTIN.Objective:To investigate a possible association between the
intensity of staff workload and intermediate adverse events, such as
accidental extubation, obstruction of the endotracheal tube, and accidental
disconnection of the ventilator circuit, during neonatal mechanical
ventilation in high-risk neonatal units.
Method:This prospective cohort study analyzed data of 543 newborns
from public neonatal intensive care units (NICUs) in the city of São LuÃs,
state of Maranhão, Northeastern Brazil, for 6 months, during which 136
newborns were submitted to mechanical ventilation in 1,108 shifts and
were observed a total of 4,554 times.
Results: Adverse events occurred 117 times during this period. The
associations between workload and adverse events were analyzed by
means of generalized estimating equations. The adjustment variables
were: birth weight, gender, maternity unit, Clinical Risk Index for Babies
score, and care demand, the latter measured by the Northern Neonatal
Network Scale. The larger the number of newborns classified by care
demand (NCCD) per nurse and nursing technician, the more likely the
occurrence of intermediate adverse events linked to mechanical ventilation.
A number of NCCD > 22 per nurse (relative risk [RR] = 2.86) and > 4.8
per auxiliary nurse (RR = 3.41) was associated with a higher prevalence
of intermediate adverse events.
Conclusions: The workload of NICU professionals seems to interfere
with the intermediate results of neonatal care and thus should be taken
into consideration when evaluating NICU outcome
Perinatal and early life factors associated with symptoms of depression in Brazilian children
Abstract Background Few studies have been conducted on the association between perinatal and early life factors with childhood depression and results are conflicting. Our aim was to estimate the prevalence and perinatal and early life factors associated with symptoms of depression in children aged 7 to 11 years from two Brazilian birth cohorts. Methods The study was conducted on 1444 children whose data were collected at birth and at school age, in 1994 and 2004/2005 in Ribeirao Preto, where they were aged 10–11 years and in 1997/98 and 2005/06 in São LuÃs, where children were aged 7–9 years. Depressive symptoms were investigated with the Child Depression Inventory(CDI), categorized as yes (score ≥ 20) and no (score Results The prevalence of depressive symptoms was 3.9% (95%CI = 2.5-5.4) in Ribeirão Preto and 13.7% (95%CI = 11.0-16.4) in São LuÃs. In the adjusted analysis, in Ribeirão Preto, low birth weight (PR = 3.98; 95%CI = 1.72-9.23), skilled and semi-skilled manual occupation (PR = 5.30; 95%CI = 1.14-24.76) and unskilled manual occupation and unemployment (PR = 6.65; 95%CI = 1.16-38.03) of the household head were risk factors for depressive symptoms. In São LuÃs, maternal schooling of 0–4 years (PR = 2.39; 95%CI = 1.31-4.34) and of 5 to 8 years (PR = 1.80; 95%CI = 1.08-3.01), and paternal age Conclusions The prevalence of depressive symptoms was much higher in the less developed city, São LuÃs, than in the more developed city, Ribeirão Preto, and than those reported in several international studies. Low socioeconomic level was associated with depressive symptoms in both cohorts. Low paternal age was a risk factor for depressive symptoms in the less developed city, São LuÃs, whereas low birth weight was a risk factor for depressive symptoms in the more developed city, Ribeirão Preto.</p
New functional bio-based materials with promising photodynamic antifouling and bacteriostatic activity
No abstract available