Electric energy production with small scale wind turbines in Viladecans (Delta del Llobregat)

The objective of this project was to determine which of the two small scale wind turbines presented (IT-PE-100 and HP-600) was the most appropriate for the wind conditions of Viladecans (Delta del Llobregat). Firstly, a wind study was conducted in order to obtain the speed distribution, using Weibull probability density function, and showed a weighted average speed of 1.46 m/s. It was decided that the best way to choose one of the two turbines would be using Fast & Aerodyn simulation software, using the previously calculated wind speed distribution, to obtain the generator power curve for each case. For the IT-PE-100 model, we used already calculated Fast & Aerodyn files from other projects conducted at Universitat Politècnica de Catalunya (UPC), and only changed the wind files, to adequate the outputs to the Viladecans area. With that wind speed distribution, the software submitted a yearly income of 99.6kWh. For the HP-600, the Fast & Aerodyn files were had to be made from scratch. Since only one of the turbine blades was available for our study, it was decided to perform a 3D digitalization. That gave us a point cloud of the blade, which was converted into a CAD file using Rapidform, a reverse engineering software. With the CAD file we were able to perform a flow simulation along the blade, using SolidWorks, in order to obtain all the necessary aerodynamic parameters needed for the creation of the Fast & Aerodyn files. These files, along with the previously calculated wind speed distribution, were used as inputs in Fast & Aerodyn, which gave us a yearly income of 66kWh, which was to be expected, since this wind turbine model is thought to work at higher wind speeds. Therefore, it was concluded that the best option for the Viladecans area was the IT-PE-100 small scale wind turbine.L’objectiu d’aquest projecte és determinar quin dels dos aerogeneradors proposats ( IT - PE - 100 i HP - 600) és el més apropiat per les condicions de v ent a Viladecans (Delta del Llobregat). Primerament, es va dur a terme un estudi del vent, amb l’objectiu d’obtenir la distribució de velocitats fent servir la funció de densitat de probabilitat de Weibull. Aquesta distribució va resultar en una mitja pon derada de velocitats de 1.46 m/s. Es va decidir que la millor manera d’escollir una de les dues turbines seria fer servir el software de simulació Fast & Aerodyn, fent servir com a inputs la distribució de probabilitat del vent prèviament calculada, junta ment amb arxius de caracterització dels aerogeneradors, amb tal d’obtenir la corba de potència per cada cas. Pel model IT - PE - 100 es van fer servir arxius de Fast & Aerodyn ja generats, extrets d’altres projectes fets a la Universitat Politècnica de Catalu nya (UPC). Per tal d’adequar els resultats a l’àrea de Viladecans, només es van haver de modificar els arxius relatius al vent. Amb aquests inputs, el software va reportar una producció energètica anual de 99.6kWh. Amb el cas de l’aerogenerador HP - 600, el s arxius de Fast & Aerodyn van haver de ser creats de forma íntegra. Degut a que només teníem a la nostra disposició una de les pales de la turbina, es va decidir fer una digitalització en 3D d’aquesta. Aquest procés ens va donar el núvol de punts de la pa la, que va ser convertit a un arxiu de tipus CAD mitjançant el software d’enginyeria inversa Rapidform. Important l’arxiu de CAD a SolidWorks, va ser possible fer una simulació de flux al voltant de la pala, que ens va permetre obtenir tots els paràmetres aerodinàmics necessaris per la creació dels inputs demanats per Fast & Aerodyn. Aquests arxius, juntament amb la distribució de vents que va ser calculada prèviament, ens van reportar una producció energètica anual inferior de 66.3kWh. Per tant, es va con cloure que la millor opció per l’àrea de Viladecans era fer servir l’aerogenerador IT - PE - 100

In-situ approach for thermal energy storage and thermoelectricity generation on the Moon: Modelling and simulation

Human, tele-operated rovers, and surface infrastructures are now being actively considered for lunar polar exploration. Current approaches to energy provision consider, among others, hybrid direct energy/chemical technologies, such as solar photovoltaic arrays, batteries, and regenerative fuel cells. Due to the long period of darkness on the Moon and the challenges this poses to the aforementioned conventional energy generation and storage technologies, there is a need to assess the potential of In-Situ Resources Utilization (ISRU) methods to enable or supplement long duration missions. We present a computational model (MATLAB) of a Thermal Energy Storage (TES) system coupled to drive a heat engine (Thermoelectric Generator) to produce electricity. The TES medium designed is based off processed lunar regolith, an abundant material present on the surface of the Moon. The architecture has been optimized to provide a minimum electrical power of 36 W per unit after 66 h of polar night, but the modular nature of the model allows other ranges of parameter to be simulated. A trade-off between this ISRU-based concept and conventional approaches for energy production and storage was performed and ranked TES and thermoelectricity generation as the least appropriate option. This result is valuable in a period of enthusiasm towards ISRU. It shows that processes exploiting extraterrestrial materials instead of Earth supplies are not systematically attractive. Despite the non-favorable performances for the proposed concept, some perspectives for the TES system are given as well as potential model improvements such as the need to assess the use of a Stirling heat engine

Heavy quarkonium: progress, puzzles, and opportunities

A golden age for heavy quarkonium physics dawned a decade ago, initiated by the confluence of exciting advances in quantum chromodynamics (QCD) and an explosion of related experimental activity. The early years of this period were chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in 2004, which presented a comprehensive review of the status of the field at that time and provided specific recommendations for further progress. However, the broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles could only be partially anticipated. Since the release of the YR, the BESII program concluded only to give birth to BESIII; the $B$-factories and CLEO-c flourished; quarkonium production and polarization measurements at HERA and the Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the deconfinement regime. All these experiments leave legacies of quality, precision, and unsolved mysteries for quarkonium physics, and therefore beg for continuing investigations. The plethora of newly-found quarkonium-like states unleashed a flood of theoretical investigations into new forms of matter such as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b}, and b\bar{c} bound states have been shown to validate some theoretical approaches to QCD and highlight lack of quantitative success for others. The intriguing details of quarkonium suppression in heavy-ion collisions that have emerged from RHIC have elevated the importance of separating hot- and cold-nuclear-matter effects in quark-gluon plasma studies. This review systematically addresses all these matters and concludes by prioritizing directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K. Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D. Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A. Petrov, P. Robbe, A. Vair

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Development of a Lunar Regolith Thermal Energy Storage Model for a Lunar Outpost

The Moon has always been an important milestone in space exploration. After the Apollo landings, it is logical to think that the next step should be a permanent habitation module, which would serve as a testing ground for more ambitious projects to Mars and beyond. For a lunar base to come into realization, it is necessary to assess a number of technological challenges which are due to the harsh conditions that can be found on the Earth's satellite. One of these tasks revolves around energy storage: During the day it is possible to use photovoltaic cells and convert the solar irradiance into electrical energy to power an outpost, however during the lunar night this source is not available. Current investigations establish that the optimal landing site for a permanent mission would be on the rim of the Shackleton crater, near the South Pole. This would reduce the night duration from 14 days to 52 hours of the lunar cycle, which is 29.5 days. While this significantly decreases the exposure to the cold temperatures of the Moon when there is no sunlight, there is still a need for a system to provide energy to the lunar base over this period. Therefore, this study pretends to serve as a possible solution for the aforementioned problem, by developing a system storing energy as thermal energy and then harvesting it as electricity using thermoelectrics. First, a theoretical introduction is presented, where the problem statement is exposed, along with background information regarding the solar illumination and the lunar soil. At the same time, an insight on regolith sintering techniques is given. These techniques are important as a means to providing thermal energy storage during the night cycle. After this, the core of the study is developed: The ideal system for energy storage is broken down into segments, and each of them is explained attending to the possible requirements of a lunar base, while providing supporting simulations when deemed appropriate. These are the solar concentrator, thermal mass, thermoelectric array, cold sink and, if necessary, a pipe network. Following this chapter, a device is proposed. Based on the previously mentioned guidelines, an ideal thermal energy system is simulated and evaluated. Although it is not optimized for efficient energy harvesting, it serves as insight on the design and simulation constraints that appear when one wants to collect electrical energy from thermoelectrics with relatively low efficiency. It was estimated that the prototype would output a mean power of 3.6 Watts over the whole duration of the lunar night. Although in its current state this technology would not present significant benefits over existing energy storage methods such as nickel-hydrogen batteries, this study also proposed several optimization methods which could vastly increase the performance of the device. These include adding more efficient thermoelectric patterns, or modifying the properties of the semiconductors by doping or using nanostructures, and present follow-on opportunities for further research

Electric energy production with small scale wind turbines in Viladecans (Delta del Llobregat)

The objective of this project was to determine which of the two small scale wind turbines presented (IT-PE-100 and HP-600) was the most appropriate for the wind conditions of Viladecans (Delta del Llobregat). Firstly, a wind study was conducted in order to obtain the speed distribution, using Weibull probability density function, and showed a weighted average speed of 1.46 m/s. It was decided that the best way to choose one of the two turbines would be using Fast & Aerodyn simulation software, using the previously calculated wind speed distribution, to obtain the generator power curve for each case. For the IT-PE-100 model, we used already calculated Fast & Aerodyn files from other projects conducted at Universitat Politècnica de Catalunya (UPC), and only changed the wind files, to adequate the outputs to the Viladecans area. With that wind speed distribution, the software submitted a yearly income of 99.6kWh. For the HP-600, the Fast & Aerodyn files were had to be made from scratch. Since only one of the turbine blades was available for our study, it was decided to perform a 3D digitalization. That gave us a point cloud of the blade, which was converted into a CAD file using Rapidform, a reverse engineering software. With the CAD file we were able to perform a flow simulation along the blade, using SolidWorks, in order to obtain all the necessary aerodynamic parameters needed for the creation of the Fast & Aerodyn files. These files, along with the previously calculated wind speed distribution, were used as inputs in Fast & Aerodyn, which gave us a yearly income of 66kWh, which was to be expected, since this wind turbine model is thought to work at higher wind speeds. Therefore, it was concluded that the best option for the Viladecans area was the IT-PE-100 small scale wind turbine.L’objectiu d’aquest projecte és determinar quin dels dos aerogeneradors proposats ( IT - PE - 100 i HP - 600) és el més apropiat per les condicions de v ent a Viladecans (Delta del Llobregat). Primerament, es va dur a terme un estudi del vent, amb l’objectiu d’obtenir la distribució de velocitats fent servir la funció de densitat de probabilitat de Weibull. Aquesta distribució va resultar en una mitja pon derada de velocitats de 1.46 m/s. Es va decidir que la millor manera d’escollir una de les dues turbines seria fer servir el software de simulació Fast & Aerodyn, fent servir com a inputs la distribució de probabilitat del vent prèviament calculada, junta ment amb arxius de caracterització dels aerogeneradors, amb tal d’obtenir la corba de potència per cada cas. Pel model IT - PE - 100 es van fer servir arxius de Fast & Aerodyn ja generats, extrets d’altres projectes fets a la Universitat Politècnica de Catalu nya (UPC). Per tal d’adequar els resultats a l’àrea de Viladecans, només es van haver de modificar els arxius relatius al vent. Amb aquests inputs, el software va reportar una producció energètica anual de 99.6kWh. Amb el cas de l’aerogenerador HP - 600, el s arxius de Fast & Aerodyn van haver de ser creats de forma íntegra. Degut a que només teníem a la nostra disposició una de les pales de la turbina, es va decidir fer una digitalització en 3D d’aquesta. Aquest procés ens va donar el núvol de punts de la pa la, que va ser convertit a un arxiu de tipus CAD mitjançant el software d’enginyeria inversa Rapidform. Important l’arxiu de CAD a SolidWorks, va ser possible fer una simulació de flux al voltant de la pala, que ens va permetre obtenir tots els paràmetres aerodinàmics necessaris per la creació dels inputs demanats per Fast & Aerodyn. Aquests arxius, juntament amb la distribució de vents que va ser calculada prèviament, ens van reportar una producció energètica anual inferior de 66.3kWh. Per tant, es va con cloure que la millor opció per l’àrea de Viladecans era fer servir l’aerogenerador IT - PE - 100

Electric energy production with small scale wind turbines in Viladecans (Delta del Llobregat)

The objective of this project was to determine which of the two small scale wind turbines presented (IT-PE-100 and HP-600) was the most appropriate for the wind conditions of Viladecans (Delta del Llobregat). Firstly, a wind study was conducted in order to obtain the speed distribution, using Weibull probability density function, and showed a weighted average speed of 1.46 m/s. It was decided that the best way to choose one of the two turbines would be using Fast & Aerodyn simulation software, using the previously calculated wind speed distribution, to obtain the generator power curve for each case. For the IT-PE-100 model, we used already calculated Fast & Aerodyn files from other projects conducted at Universitat Politècnica de Catalunya (UPC), and only changed the wind files, to adequate the outputs to the Viladecans area. With that wind speed distribution, the software submitted a yearly income of 99.6kWh. For the HP-600, the Fast & Aerodyn files were had to be made from scratch. Since only one of the turbine blades was available for our study, it was decided to perform a 3D digitalization. That gave us a point cloud of the blade, which was converted into a CAD file using Rapidform, a reverse engineering software. With the CAD file we were able to perform a flow simulation along the blade, using SolidWorks, in order to obtain all the necessary aerodynamic parameters needed for the creation of the Fast & Aerodyn files. These files, along with the previously calculated wind speed distribution, were used as inputs in Fast & Aerodyn, which gave us a yearly income of 66kWh, which was to be expected, since this wind turbine model is thought to work at higher wind speeds. Therefore, it was concluded that the best option for the Viladecans area was the IT-PE-100 small scale wind turbine.L’objectiu d’aquest projecte és determinar quin dels dos aerogeneradors proposats ( IT - PE - 100 i HP - 600) és el més apropiat per les condicions de v ent a Viladecans (Delta del Llobregat). Primerament, es va dur a terme un estudi del vent, amb l’objectiu d’obtenir la distribució de velocitats fent servir la funció de densitat de probabilitat de Weibull. Aquesta distribució va resultar en una mitja pon derada de velocitats de 1.46 m/s. Es va decidir que la millor manera d’escollir una de les dues turbines seria fer servir el software de simulació Fast & Aerodyn, fent servir com a inputs la distribució de probabilitat del vent prèviament calculada, junta ment amb arxius de caracterització dels aerogeneradors, amb tal d’obtenir la corba de potència per cada cas. Pel model IT - PE - 100 es van fer servir arxius de Fast & Aerodyn ja generats, extrets d’altres projectes fets a la Universitat Politècnica de Catalu nya (UPC). Per tal d’adequar els resultats a l’àrea de Viladecans, només es van haver de modificar els arxius relatius al vent. Amb aquests inputs, el software va reportar una producció energètica anual de 99.6kWh. Amb el cas de l’aerogenerador HP - 600, el s arxius de Fast & Aerodyn van haver de ser creats de forma íntegra. Degut a que només teníem a la nostra disposició una de les pales de la turbina, es va decidir fer una digitalització en 3D d’aquesta. Aquest procés ens va donar el núvol de punts de la pa la, que va ser convertit a un arxiu de tipus CAD mitjançant el software d’enginyeria inversa Rapidform. Important l’arxiu de CAD a SolidWorks, va ser possible fer una simulació de flux al voltant de la pala, que ens va permetre obtenir tots els paràmetres aerodinàmics necessaris per la creació dels inputs demanats per Fast & Aerodyn. Aquests arxius, juntament amb la distribució de vents que va ser calculada prèviament, ens van reportar una producció energètica anual inferior de 66.3kWh. Per tant, es va con cloure que la millor opció per l’àrea de Viladecans era fer servir l’aerogenerador IT - PE - 100

4Th Pediatric Allergy And Asthma Meeting (Paam)

WORKSHOP 4: Challenging clinical scenarios (CS01–CS06), CS01 Bullous lesions in two children: solitary mastocytoma, S. Tolga Yavuz, Ozan Koc, Ali Gungor, Faysal Gok, CS02 Multi-System Allergy (MSA) of cystic fibrosis: our institutional experience, Jessica Hawley, Christopher O’Brien, Matthew Thomas, Malcolm Brodlie, Louise Michaelis, CS03 Cold urticaria in pediatric age: an invisible cause for severe reactions, Inês Mota, Ângela Gaspar, Susana Piedade, Graça Sampaio, José Geraldo Dias, Miguel Paiva, Mário Morais-Almeida, CS04 Angioedema with C1 inhibitor deficiency in a girl: a challenge diagnosis, Cristina Madureira, Tânia Lopes, Susana Lopes, Filipa Almeida, Alexandra Sequeira, Fernanda Carvalho, José Oliveira, CS05 A child with unusual multiple organ allergy disease: what is the primer?, Fabienne Gay-Crosier, CS06 A case of uncontrolled asthma in a 6-year-old patient, Ioana-Valentina Nenciu, Andreia Florina Nita, Alexandru Ulmeanu, Dumitru Oraseanu, Carmen Zapucioiu, ORAL ABSTRACT SESSION 1: Food allergy (OP01–OP06), OP01 Food protein-induced enterocolitis syndrome: oral food challenge outcomes for tolerance evaluation in a Pediatric Hospital, Adrianna Machinena, Olga Domínguez Sánchez, Montserrat Alvaro Lozano, Rosa Jimenez Feijoo, Jaime Lozano Blasco, Mònica Piquer Gibert, Mª Teresa Giner Muñoz, Marcia Dias da Costa, Ana Maria Plaza Martín, OP02 Characteristics of infants with food protein-induced enterocolitis syndrome and allergic proctocolitis, Ebru Arik Yilmaz, Özlem Cavkaytar, Betul Buyuktiryaki, Ozge Soyer, Cansin Sackesen, OP03 The clinical and immunological outcomes after consumption of baked egg by 1–5 year old egg allergic children: results of a randomised controlled trial, MerrynNetting, Adaweyah El-Merhibi, Michael Gold, PatrickQuinn, IrmeliPenttila, Maria Makrides, OP04 Oral immunotherapy for treatment of egg allergy using low allergenic, hydrolysed egg, Stavroula Giavi, Antonella Muraro, Roger Lauener, Annick Mercenier, Eugen Bersuch, Isabella M. Montagner, Maria Passioti, Nicolò Celegato, Selina Summermatter, Sophie Nutten, Tristan Bourdeau, Yvonne M. Vissers, Nikolaos G. Papadopoulos, OP05 Chemical modification of a peanut extract results in an increased safety profile while maintaining efficacy, Hanneke van der Kleij, Hans Warmenhoven, Ronald van Ree, Raymond Pieters, Dirk Jan Opstelten, Hans van Schijndel, Joost Smit, OP06 Administration of the yellow fever vaccine in egg allergic children, Roisin Fitzsimons, Victoria Timms, George Du Toit, ORAL ABSTRACT SESSION 2: Asthma (OP07–OP12), OP07 Previous exacerbation is the most important risk factor for future exacerbations in school-age children with asthma, S. Tolga Yavuz, Guven Kaya, Mustafa Gulec, Mehmet Saldir, Osman Sener, Faysal Gok, OP08 Comparative study of degree of severity and laboratory changes between asthmatic children using different acupuncture modalities, Nagwa Hassan, Hala Shaaban, Hazem El-Hariri, Ahmed Kamel Inas E. Mahfouz, OP09 The concentration of exhaled carbon monoxide in asthmatic children with different controlled stadium, Papp Gabor, Biro Gabor, Kovacs Csaba, OP10 Effect of vitamin D3 supplementation during pregnancy on risk of persistent wheeze in the offspring: a randomised clinical trial, Bo Chawes, Klaus Bønnelykke, Jakob Stokholm, Lene Heickendorff, Susanne Brix, Morten Rasmussen, Hans Bisgaard, OP11 Lung function development in childhood, Henrik Wegener Hallas, Bo Chawes, Lambang Arianto, Hans Bisgaard, OP12 Is the effect of maternal and paternal asthma different in female and male children before puberty?, Maike Pincus, Thomas Keil, Andreas Reich, Ulrich Wahn, Susanne Lau, Linus Grabenhenrich, ORAL ABSTRACT SESSION 3: Epidemiology—genetics (OP13–OP18), OP13 Lifestyle is associated with incidence and category of allergen sensitisation: the ALADDIN birth cohort, Sara Fagerstedt, Helena Marell Hesla, Emelie Johansson, Helen Rosenlund, Axel Mie, Annika Scheynius, Johan Alm, OP15 Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance, Jorge Esparza-Gordillo, Anja Matanovic, Ingo Marenholz, Anja Bauerfeind, Klaus Rohde, Katja Nemat, Min-Ae Lee-Kirsch, Magnus Nordenskjöld, Marten C. G. Winge, Thomas Keil, Renate Krüger, Susanne Lau, Kirsten Beyer, Birgit Kalb, Bodo Niggemann, Norbert Hübner, Heather J. Cordell, Maria Bradley, Young-Ae Lee, OP16 Allergic multimorbidity of asthma, rhinitis and eczema in the first 2 decades of the German MAS birth cohort, Thomas Keil, Hannah Gough, Linus Grabenhenrich, Dirk Schramm, Andreas Reich, John Beschorner, Antje Schuster, Carl-Peter Bauer, Johannes Forster, Fred Zepp, Young-Ae Lee, Renate Bergmann, Karl Bergmann, Ulrich Wahn, Susanne Lau, OP17 Childhood anaphylaxis: a growing concern, Filipe Benito Garcia, Inês Mota, Susana Piedade, Ângela Gaspar, Natacha Santos, Helena Pité, Mário Morais-Almeida, OP18 Indoor exposure to molds and dampness in infancy and its association to persistent atopic dermatitis in school age. Results from the Greek ISAAC II study, Athina Papadopoulou, Despina Mermiri, Elpida Xatziagorou, Ioannis Tsanakas, Stavroula Lampidi, Kostas Priftis, ORAL ABSTRACT SESSION 4: Pediatric rhinitis—immunotherapy (OP19–OP24), OP19 Associations between residential greenness and childhood allergic rhinitis and aeroallergen sensitisation in seven birth cohorts, Elaine Fuertes, Iana Markevych, Gayan Bowatte, Olena Gruzieva, Ulrike Gehring, Allan Becker, Dietrich Berdel, Michael Brauer, Chris Carlsten, Barbara Hoffmann, Anita Kozyrskyj, Caroline Lodge, Göran Pershagen, Alet Wijga, Heinrich Joachim, OP20 Full symptom control in pediatric patients with allergic rhinitis and asthma: results of a 2-year sublingual allergen immunotherapy study, Zorica Zivkovic, Ivana Djuric-Filipovic, Jasmina Jocić-Stevanovic, Snežana Zivanovic, OP21 Nasal epithelium of different ages of atopic subjects present increased levels of oxidative stress and increased cell cytotoxicity upon rhinovirus infection, Styliani Taka, Dimitra Kokkinou, Aliki Papakonstantinou, Panagiota Stefanopoulou, Anastasia Georgountzou, Paraskevi Maggina, Sofia Stamataki, Vassiliki Papaevanggelou, Evangelos Andreakos, Nikolaos G. Papadopoulos, OP22 Cluster subcutaneous immunotherapy schedule: tolerability profile in children, Monica Piquer Gibert, Montserrat Alvaro Lozano, Jaime Lozano Blasco, Olga Domínguez Sánchez, Rosa Jiménez Feijoo, Marcia Dias da Costa, Mª Teresa Giner Muñoz, Adriana Machinena Spera, Ana Maria Plaza Martín, OP23 Rhinitis as a risk factor for asthma severity in 11-year old children: population-based cohort study, Matea Deliu, Danielle Belgrave, Angela Simpson, Adnan Custovic, OP24 The Global Lung Function Initiative equations in airway obstruction evaluation of asthmatic children, João Gaspar Marques, Pedro Carreiro-Martins, Joana Belo, Sara Serranho, Isabel Peralta, Nuno Neuparth, Paula Leiria-Pinto, POSTER DISCUSSION SESSION 1: Food allergy (PD01–PD05), PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactions, Marta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel Juan, PD02 FoxP3 epigenetic features in children with cow milk allergy, Lorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni Canani, PD04 Combined milk and egg allergy in early childhood: let them eat cake?, Santanu Maity, Giuseppina Rotiroti, Minal Gandhi, PD05 Introduction of complementary foods in relation to allergy and gut microbiota in farm and non-farm children, Karin Jonsson, Annika Ljung, Bill Hesselmar, Ingegerd Adlerbert, Hilde Brekke, Susanne Johansen, Agnes Wold, Ann-Sofie Sandberg, POSTER DISCUSSION SESSION 2: Asthma and wheeze (PD06–PD16), PD06 The association between asthma and exhaled nitric oxide is influenced by genetics and sensitisation, Björn Nordlund, Cecilia Lundholm, Villhelmina Ullemar, Marianne van Hage, Anne Örtqvist, Catarina Almqvist, PD09 Prevalence patterns of infant wheeze across Europe, Anna Selby, Kate Grimshaw, Thomas Keil, Linus Grabenhenrich, Michael Clausen, Ruta Dubakiene, Alessandro Fiocchi, Marek Kowalski, Nikos Papadopoulos, Marta Reche, Sigurveig Sigurdardottir, Aline Sprikkleman, Paraskevi Xepapadaki, Clare Mills, Kirsten Beyer, Graham Roberts, PD10 Epidemiologic changes in recurrent wheezing infants, Herberto Jose Chong Neto, Gustavo Falbo Wandalsen, Ana Carolina Dela Bianca, Carolina Aranda, Nelson Augusto Rosário, Dirceu Solé, Javier Mallol, Luis García Marcos, PD13 A single nucleotide polymorphism in the GLCCI1 gene is associated with response to asthma treatment in children, IvanaBanic, Matija Rijavec, Davor Plavec, Peter Korosec, Mirjana Turkalj, PD14 Pollen induced asthma: Could small molecules in pollen exacerbate the protein-mediated allergic response?, Alen Bozicevic, Maria De Mieri, Matthias Hamburger, PD15 A qualitative study to understand how we can empower teenagers to better self-manage their asthma, Simone Holley, Ruth Morris, Frances Mitchell, Rebecca Knibb, Susan Latter, Christina Liossi, Graham Roberts, PD16 Polymorphism of endothelial nitric oxide synthase (eNOS) gene among Egyptian children with bronchial asthma, Mostafa M. M. Hassan, POSTER DISCUSSION SESSION 3: Mechanisms—Epidemiology (PD17–PD21), PD17 Pregnancy outcomes in relation to development of allergy in a Swedish birth cohort, Malin Barman, Anna Sandin, Agnes Wold, Ann-Sofie Sandberg, PD18 Evolution of the IgE response to house dust mite molecules in childhood, Daniela Posa, Serena Perna, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Ulrich Wahn, Thomas Keil, Susanne Lau, Kuan-Wei Chen, Yvonne Resch, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi, PD19 Antibody recognition of nsLTP-molecules as antigens but not as allergens in the German-MAS birth cohort, Olympia Tsilochristou, Alexander Rohrbach, Antonio Cappella, Stephanie Hofmaier, Laura Hatzler, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, RaffaeleD’Amelio, Ulrich Wahn, Thomas Keil, Susanne Lau, Paolo Maria Matricardi, PD20 Early life colonization with Lactobacilli and Staphylococcus aureus oppositely associates with the maturation and activation of FOXP3+ CD4 T-cells, Sophia Björkander, Maria A. Johansson, Gintare Lasaviciute, Eva Sverremark-Ekström, PD21 Genome-wide meta-analysis identifies 7 susceptibility loci involved in the atopic march, Ingo Marenholz, Jorge Esparza-Gordillo, Franz Rüschendorf, Anja Bauerfeind, David P. Strachan, Ben D. Spycher, Hansjörg Baurecht, Patricia Margaritte-Jeannin, Annika Sääf, Marjan Kerkhof, Markus Ege, Svetlana Baltic, Melanie C Matheson, Jin Li, Sven Michel, Wei Q. Ang, Wendy McArdle, Andreas Arnold, Georg Homuth, Florence Demenais, Emmanuelle Bouzigon, Cilla Söderhäll, Göran Pershagen, Johan C. de Jongste, Dirkje S Postma, Charlotte Braun-Fahrländer, Elisabeth Horak, Ludmila M. Ogorodova, Valery P. Puzyrev, Elena Yu Bragina, Thomas J Hudson, Charles Morin, David L Duffy, Guy B Marks, Colin F Robertson, Grant W Montgomery, Bill Musk, Philip J Thompson, Nicholas G. Martin, Alan James, Patrick Sleiman, Elina Toskala, Elke Rodriguez, Regina Fölster-Holst, Andre Franke, Wolfgang Lieb, Christian Gieger, Andrea Heinzmann, Ernst Rietschel, Thomas Keil, Sven Cichon, Markus M Nöthen, Craig E Pennell, Peter D Sly, Carsten O Schmidt, Anja Matanovic, Valentin Schneider, Matthias Heinig, Norbert Hübner, Patrick G. Holt, Susanne Lau, Michael Kabesch, Stefan Weidinger, Hakon Hakonarson, Manuel AR Ferreira, Catherine Laprise, Maxim B. Freidin, Jon Genuneit, Gerard H Koppelman, Erik Melén, Marie-Hélène Dizier, A. John Henderson, Young Ae Lee, POSTER DISCUSSION SESSION 4: Food allergy—Anaphylaxis (PD22–PD26), PD22 Atopy patch test in food protein induced enterocolitis caused by solid food, Purificacion González-Delgado, Esther Caparrós, Fernando Clemente, Begoña Cueva, Victoria M. Moreno, Jose Luis Carretero, Javier Fernández, PD23 Watermelon allergy: a novel presentation, Kate Swan, George Du Toit, PD24 A pilot study evaluating the usefulness of a guideline template for managing milk allergy in primary care, Mudiyur Gopi, Tim Smith, Edara Ramesh, Arun Sadasivam, PD26 Efficacy and safety of cow’s milk oral immunotherapy protocol, Inês Mota, Filipe Benito Garcia, Susana Piedade, Angela Gaspar, Graça Sampaio, Cristina Arêde, Luís Miguel Borrego, Graça Pires, Cristina Santa-Marta, Mário Morais-Almeida, POSTER DISCUSSION SESSION 5: Prevention and treatment—Allergy (PD27–PD36), PD27 Allergy-protection by the lactic acid bacterium Lactococcus lactis G121: mode-of-action as revealed in a murine model of experimental allergy, Stephanie Brand, Karina Stein, Holger Heine, Marion Kauth, PD29 The relationship between quality of life and morning salivary cortisol after acute bronchiolitis in infancy, Leif Bjarte Rolfsjord, Egil Bakkeheim, Johan Alm, Håvard Ove Skjerven, Kai-Håkon Carlsen, Jon Olav Hunderi, Teresa Løvold Berents, Petter Mowinckel, Karin C. Lødrup Carlsen, PD30 Randomised trial of the efficacy of MP29-02* compared with fluticasone propionate nasal spray in children aged ≥6 years to <12 years with allergic rhinitis, Ulrich Wahn, Ullrich Munzel, William Berger, PD31 10 mg of oral bilastine in 2 to 11 years old children has similar exposure to the adult therapeutic dose (20 mg), Ulrich Wahn, Román Valiente, Valvanera Vozmediano, John C. Lukas, Mónica Rodríguez, PD33 Daily symptoms, nocturnal symptoms, activity limitations and reliever therapies during the three steps of IOEASMA programme: a comparison, Sebastiano Guarnaccia, Luigi Vitale, Ada Pluda, Emanuele D’Agata, Denise Colombo, Stefano Felici, Valeria Gretter, Susanna Facchetti, Gaia Pecorelli, Cristina Quecchia, PD34 Sensitisation to an inert aeroallergen in weaning rats and longstanding disease, in a sensitisation-tolerant and easily tolerisable rodent strain, George Guibas, Evangelia Spandou, Spyridon Megremis, Peter West, Nikolaos Papadopoulos, PD35 Bacterial and fungi exposure in school and allergic sensitisation in children, João Cavaleiro Rufo, Joana Madureira, Inês Paciência, Lívia Aguiar, Patrícia Padrão, Mariana Pinto, Luís Delgado, Pedro Moreira, João Paulo Teixeira, Eduardo Oliveira Fernandes, André Moreira, PD36 Comparative study of allergy rhinitis between two populations: children vs. adults, Adriana Izquierdo Dominguez, Antonio Valero, Joaquim Mullol, Alfonso Del Cuvillo, Javier Montoro, Ignacio Jauregui, Joan Bartra, Ignacio Davila, Marta Ferrer, Joaquin Sastre, POSTER VIEWING SESSION 1: Inflammation—Genetics—Immunology—Dermatology (PP01–PP09), PP01 Immune profile in late pregnancy: immunological markers in atopic asthmaticwomen as risk factors for atopy in the progeny, Catarina Martins, Jorge Lima, Maria José Leandro, Glória Nunes, Jorge Cunha Branco, Hélder Trindade, Luis Miguel Borrego, PP02 The impact of neonatal sepsis on development of allergic diseases, Secil Conkar, Mehtap Kilic, Canan Aygun, Recep Sancak, PP03 Clinical overview of selective IgE deficiency in childhood, Athina Papadopoulou, Eleni Tagalaki, Lambros Banos, Anna Vlachou, Fotini Giannoula, Despina Mermiri, PP04 Inverse relationship between serum 25(ΟΗ) vitamin D3 and total IgE in children and adolescence, Athina Papadopoulou, Stavroula Lampidi, Marina Pavlakou, Maria Kryoni, Kostas Makris, PP05, PP06, PP07 Asthma control questionnaire and specific IgE in children, Snezhina Lazova, Guergana Petrova, Dimitrinka Miteva, Penka Perenovska, PP08 Features of chronic urticaria of adolescents, Aliya Klyucharova, Olesya Skorohodkina, PP09 Cutaneous mastocytosis in children: a clinical analysis of 8 cases in Greece, Dimitra Koumaki, Alkisti Manousaki, Maria Agrapidi, Lida Iatridou, Omima Eruk, Konstantinos Myridakis, Emmanouil Manousakis, Vasiliki Koumaki, POSTER VIEWING SESSION 2: Food allergy—Anaphylaxis (PP10–PP47), PP10 Prognostic factors in egg allergy, Maria Dimou, Maria Ingemansson, Gunilla Hedlin, PP11 Evaluation of the efficacy of an amino acid-based formula in infants who are intolerant to extensively hydrolysed protein formula, Nitida Pastor, Delphine de Boissieu, Jon Vanderhoof, Nancy Moore, Kaitlin Maditz, PP12 Anaphylaxis and epinephrine auto-injector use: a survey of pediatric trainees, Adeli Mehdi, Shaza Elhassan, Carolin Beck, Ahmed Al-Hammadi, PP13 Anaphylaxis in children: acute management in the Emergency Department, Ioana Maris, Ronan O’Sullivan, Jonathan Hourihane,, PP14 Understanding Cumbrian schools preparedness in managing children at risk of anaphylaxis in order to provide training and support which will create healthy and safe environments for children with allergies, George Raptis, Louise Michaelis, PP15 A new valid and reliable parent and child questionnaire to measure the impact of food protein enterocolitis syndrome on children: the FPIES Quality of Life Questionnaire (FPIESQL), Parent and Child Short Form, Audrey DunnGalvin, Matthew Greenhawt, Carina Venter, Jonathan Hourihane, PP16 An in-depth case study investigation of the experiences of teenagers and young adults in growing up and living with food allergy with emphasis on coping, management and risk, support, and social and self-identity, Evelyn O’Regan, Duncan Cronin, Jonathan Hourihane, Anna O’Reilly, Audrey DunnGalvin, PP17 Cow’s milk protein allergy in Constantine. A retrospective study of 62 cases between 1996 and 2013, Foued Abdelaziz, Dounia Khelifi-Touhami, Nihad Selim, Tahar Khelifi-Touhami, PP18, PP19 Cow’s milk and egg oral immunotherapy in children older than 5 years, Pablo Merida, Ana Mª Plaza, Juan Heber Castellanos, Adrianna Machinena, Montserrat Alvaro Lozano, Jaime Lozano, Olga Dominguez, Monica Piquer, Rosa Jimenez, Mª Teresa Giner, PP20 Professionals’ awareness of management of Cow’s Milk Protein Allergy (CMPA) in North Wales Hospitals, Konstantinos Kakleas, Manohar Joishy, Wendmu Maskele, Huw R. Jenkins, PP21, PP22 Anaphylaxis: the great unknown for teachers. Presentation of a protocol for schools, Mercedes Escarrer, Agustín Madroñero, Maria Teresa Guerra, Juan Carlos Julia, Juan Carlos Cerda, Javier Contreras, Eulalia Tauler, Maria Jesus Vidorreta, Ana Rojo, Silvia Del Valle, PP23 Challenges facing children with food allergies and their parents in out of school activity sectors, Niamh Flynn, PP24 A review of food challenges at a Regional Irish Centre, Gary Foley, Carol Harmon, John Fitzsimons, PP25 The use of epinephrine in infants with anaphylaxis, Krasimira Baynova, Ávila Maria Del Robledo, Labella Marina, PP26, PP27, PP28 Mother’s psychological state predicts the expression of symptoms in food allergic children, Aaron Cortes, Alicia Sciaraffia, Angela Castillo, PP29 The correlation between sIgE towards tree nuts and birch pollen in a Danish Pediatric Allergy Clinic, Nanna Juel-Berg, Kirsten Skamstrup Hansen, Lars Kærgaard Poulsen, PP30 Food allergy in children: evaluation of parents’ use of online social media, Andreia Florina Nita, Ioana Valentina Nenciu, Adina Lazar, Dumitru Oraseanu, PP31 The impact of food allergy on quality of life: FAQLQ questionnaire, Rita Aguiar, Anabela Lopes, Maria J. Paes, Amélia S. Santos, M. A. Pereira-Barbosa, PP32 An unexpected cause of anaphylaxis: potato, Hatice Eke Gungor, Salih Uytun, Umit Murat Sahiner, Yasemin Altuner Torun, PP33 Is it clinical phenotype of allergic diseases determined by sensitisation to food?, Mirjana Zivanovic, Marina Atanasković-Marković, PP34, PP35 Prescribing adrenaline auto-injectors in children in 2014: the data from regional pediatricians, Tina Vesel, Mihaela Nahtigal, Andreja Obermayer-Temlin, Eva Šoster Križnik, Mirjana Maslar, Ruben Bizjak, Marjeta Tomšič-Matic, Sonja Posega-Devetak, Maja Skerbinjek-Kavalar, Mateja Predalič, Tadej Avčin, PP36 Who should have an adrenaline autoinjector? Adherence to the European and French guidelines among 121 allergists from the Allergy Vigilance Network, Guillaume Pouessel, Etienne Beaudouin, Anne M. Moneret-Vautrin, Antoine Deschildre, Allergy Vigilance Network, PP37 Anaphylaxis by Anacardium Occidentale, Marta Viñas, Bartolomé Borja, Nora Hernández, Mª José Castillo, Adriana Izquierdo, Marcel Ibero, PP38 Anaphylaxis with honey in a child, S. Tolga Yavuz, Ali Gungor, Betul Buyuktiryaki, Ozan Koc, Can Naci Kocabas, Faysal Gok, PP39 Evaluation of courses adopted to children on prevention, recognition and management of anaphylaxis, Tina Vesel, Mihaela Nahtigal, PP40 Symptomatic dust mites and shrimp allergy: three pediatric case reports, Filipa Almeida, Susana Lopes, Cristina Madureira, Tânia Lopes, Fernanda Carvalho, PP41 Poor identification rates of nuts by high risk individuals: a call for improved education and support for families, Camille Heming, Emily Garrett, Adam Blackstock, Santanu Maity, Rahul Chodhari, PP42 DAFALL: database of food allergies in the Czech Republic, Simona Belohlavkova, Eliska Kopelentova, Petr Visek, Ivana Setinova, Ivana Svarcova, PP43 Serological cross-reactivity between grass and wheat is not only caused by profilins and CCDs, Sigrid Sjölander, Nora Nilsson, Malin Berthold, Helena Ekoff, Gunilla Hedlin, Magnus Borres, Caroline Nilsson, PP44 Oil body associated proteins in children with nuts allergy. Allergens to consider in IgE-mediated nuts allergy, Loreto González Domínguez, Cristina Muñoz Archidona, Ana Moreira Jorge, Sergio Quevedo Teruel, Teresa Bracamonte Bermejo, Miriam Castillo Fernández, Fernando Pineda de la Losa, Luis Ángel Echeverría Zudaire, PP45, PP46 Protective effect of helicobacter pylori infection against food allergy in children, Olga Vrani, Antigone Mavroudi, Maria Fotoulaki, Maria Emporiadou, Kleomenis Spiroglou, Ioannis Xinias, PP47 Anaphylaxis pathway: A road tryp-tase to success?, Helyeh A. Sadreddini, Mia Warnes, Donna Traves, POSTER VIEWING SESSION 3: Miscell

First Measurement of the Total Inelastic Cross-Section of Positively-Charged Kaons on Argon at Energies Between 5.0 and 7.5 GeV

International audienceProtoDUNE Single-Phase (ProtoDUNE-SP) is a 770-ton liquid argon time projection chamber that operated in a hadron test beam at the CERN Neutrino Platform in 2018. We present a measurement of the total inelastic cross section of charged kaons on argon as a function of kaon energy using 6 and 7 GeV/$c$ beam momentum settings. The flux-weighted average of the extracted inelastic cross section at each beam momentum setting was measured to be 380$\pm$26 mbarns for the 6 GeV/$c$ setting and 379$\pm$35 mbarns for the 7 GeV/$c$ setting

The DUNE Far Detector Vertical Drift Technology, Technical Design Report

International audienceDUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals