75 research outputs found
Comprehensive assessment of metabolic syndrome among rural Bangladeshi women
Background: Metabolic syndrome (MS), defined as a constellation of cardiovascular disease (CVD) risk factors, is one of the fastest growing public health burdens in the Asia-Pacific region. This trend is despite the fact that people in this region are no more overweight than Europeans and Americans. Unfortunately, in South Asia, MS screening has only been performed in a few countries other than Bangladesh. Therefore the present study is designed to conduct a comprehensive screening of MS in Bangladeshi rural women, which includes estimation of prevalence and assessment of risk factor. Methods: A total of 1535 rural Bangladesh women aged ≥ 15 years were studied using a population based crosssectional survey. The prevalence of MS was estimated using NCEP ATP III, modified NCEP ATP III and IDF criteria. Results: The prevalence rates of MS were 25.60 % (NCEP ATP III), 36.68 % (modified NCEP ATP III), and 19.80 % (IDF), as revealed by the present study. Furthermore, based on the NCEP ATP III criteria, 11.60 % of the subjects were found to have excess waist circumference; 29.12 % had elevated blood pressure, 30.42 % had elevated fasting plasma glucose level, 85.47 % had low HDL values and 26.91 % had increased triglyceride values. Low plasma HDL level was found to be the most common abnormality in the target population and elevated waist circumference was the least frequent component. Conclusions: The present study reveals a high prevalence of MS and its associated risk factors in rural Bangladeshi women. These findings are important in that they provide insights that will be helpful in formulating effective public health policy, notably the development of future health prevention strategies in Bangladesh
WSES guidelines for management of Clostridium difficile infection in surgical patients
In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.Peer reviewe
Review Article - Edible vaccines: Current status and future
Edible vaccines hold great promise as a cost-effective,
easy-to-administer, easy-to-store, fail-safe and socioculturally
readily acceptable vaccine delivery system, especially for the poor
developing countries. It involves introduction of selected desired
genes into plants and then inducing these altered plants to manufacture
the encoded proteins. Introduced as a concept about a decade ago, it
has become a reality today. A variety of delivery systems have been
developed. Initially thought to be useful only for preventing
infectious diseases, it has also found application in prevention of
autoimmune diseases, birth control, cancer therapy, etc. Edible
vaccines are currently being developed for a number of human and animal
diseases. There is growing acceptance of transgenic crops in both
industrial and developing countries. Resistance to genetically modified
foods may affect the future of edible vaccines. They have passed the
major hurdles in the path of an emerging vaccine technology. Various
technical obstacles, regulatory and non-scientific challenges, though
all seem surmountable, need to be overcome. This review attempts to
discuss the current status and future of this new preventive modality
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