Application of avalanche photodiodes as a readout for scintillator tile-fiber systems

The application of reach-through avalanche photodiodes (R'APD) as a photodetector for scintillator tiles has been investigated. The light collected by WLS fibers (0.84mm and 1mm diameter) embedded in the scintillator has been transmited to the 0.5mm2 active surface of APD by clear optical fibers and optical connectors. A low noise charge sensitive preamplifier (approximately 400 electrons equivalent noise charge) has been used to gain the photodiode signal. Various configurations of tile-fibre systems, suitable for CMS and LHCb experiments at LHC have been studied using cosmic muons and muon beam at SPS at CERN. In order to optimize the performance of APD, measurments in the temperature range from -10C to +25C have been done. The MIP detection efficiency and electron/MIP separation have been estimated in order to determine applicability of the readout for LHCb preshower.Comment: 20 pages,13 figure

Computer Simulation of Excitation-Contraction Coupling in Cardiac Muscle. A Study of the Regulatory Role of Calcium Binding to Troponin C

Abstract. The influence of a change of troponin concentration as well of a change of binding and dissociation of Ca 2+ ions to the íegulatoiy piotem tioponin C on the time couise of isometiic tension has been studied using a mathematical model developed to investigate excitation-conti action coupling m caidiac muscle cells The numencal simulations show that peak amplitude, íate of foice development, time to peak tension and relaxation time depend significantly on the above paiameteis even m the case when the equilibrium dissociation constant lemams unchanged The obtained íesults might be useful foi the planing of new expenments in the view of the fact that no similai data have been íepoited foi caidiac muscle cells as ye

Fundamentals of Diabetic Cataractogenesis and Promising Ways of its Pharmacological Correction

Cataracts in diabetes mellitus lead to decreased visual function and blindness. Cataract surgery for diabetes mellitus has limitations and complications. The search for effective means of conservative cataract therapy continues. The review presents the analysis of data from scientific sources, mainly for 2015–2020 using Internet resources (PubMed, Web of Science, Medline, eLibrary.Ru, Cyberleninka). In the work, diabetic cataractogenesis is presented as a sum of interrelated pathobiochemical processes. The main ones are the polyol pathway of glucose conversion, non-enzymatic glycation and oxidative modification of lens proteins, which are enhanced in diabetes mellitus. The lens has a high protein content. The formation of high molecular weight protein aggregates is of particular importance for the appearance of light scattering zones and a decrease in lens transparency. This review presents data on anti-cataract compounds that affect post-translational crystallin modification, prevent osmotic and oxidative stress in the lens, and exhibit antiglycation properties. This information shows that the search for means of pharmacological correction of cataractogenesis should be carried out among compounds with antioxidant and antiglycation activity

Observation of enhanced transmission for s-polarized light through a subwavelength slit

Enhanced optical transmission (EOT) through subwavelength apertures is usually obtained for p-polarized light. The present study experimentally investigates EOT for s-polarized light. A subwavelength slit surrounded on each side by periodic grooves has been fabricated in a gold film and covered by a thin dielectric layer. The excitation of s-polarized dielectric waveguide modes inside the dielectric film strongly increases the s-polarized transmission. Transmission measurements are compared with a coupled mode model and show good qualitative agreement. Adding a waveguide can improve light transmission through subwavelength apertures, as both s and p-polarization can be efficiently transmitted.Comment: 11 pages, 3 figures, submitted to Applied Physics Letter

Magneto-Optical and Multiferroic Properties of Transition-Metal (Fe, Co, or Ni)-Doped ZnO Layers Deposited by ALD

ZnO doped with transition metals (Co, Fe, or Ni) that have non-compensated electron spins attracts particular interest as it can induce various magnetic phenomena and behaviors. The advanced atomic layer deposition (ALD) technique makes it possible to obtain very thin layers of doped ZnO with controllable thicknesses and compositions that are compatible with the main microelectronic technologies, which further boosts the interest. The present study provides an extended analysis of the magneto optical MO Kerr effect and the dielectric properties of (Co, Fe, or Ni)-doped ZnO films prepared by ALD. The structural, magneto optical, and dielectric properties were considered in relation to the technological details of the ALD process and the corresponding dopant effects. All doped samples show a strong MO Kerr behavior with a substantial magnetization response and very high values of the Kerr polarization angle, especially in the case of ZnO/Fe. In addition, the results give evidence that Fe-doped ZnO also demonstrates a ferroelectric behavior. In this context, the observed rich and versatile physical nature and functionality open up new prospects for the application of these nanostructured materials in advanced electronic, spintronic, and optical devices

Multiband optical variability of the blazar OJ 287 during its outbursts in 2015 -- 2016

We present recent optical photometric observations of the blazar OJ 287 taken during September 2015 -- May 2016. Our intense observations of the blazar started in November 2015 and continued until May 2016 and included detection of the large optical outburst in December 2016 that was predicted using the binary black hole model for OJ 287. For our observing campaign, we used a total of 9 ground based optical telescopes of which one is in Japan, one is in India, three are in Bulgaria, one is in Serbia, one is in Georgia, and two are in the USA. These observations were carried out in 102 nights with a total of ~ 1000 image frames in BVRI bands, though the majority were in the R band. We detected a second comparably strong flare in March 2016. In addition, we investigated multi-band flux variations, colour variations, and spectral changes in the blazar on diverse timescales as they are useful in understanding the emission mechanisms. We briefly discuss the possible physical mechanisms most likely responsible for the observed flux, colour and spectral variability.Comment: 11 pages, 6 figures, 4 tables; Accepted for publication in MNRA