56 research outputs found
Пептидные аналоги эпитопов взаимодействия протеина А с иммуноглобулинами класса G, их синтез и исследование целевых свойств
Get PDFUsing methods of theoretical conformational analysis, the Phe-Gln-Phe-Tyr-OMe tetrapeptide has been designed and synthesized. Amino acid fragments of this tetrapeptide are present in the active center of protein A, providing its binding with the Fc-fragment of human IgG antibodies. Activity of this tetrapeptide has been confirmed by studies of its binding affinity with Fc-fragment of human IgG antibodies.С помощью методов теоретического конформационного анализа отобрана структура и осуществлен синтез тетра-пептида формулы Phe-Gln-Phe-Tyr-OMe, аминокислотные остатки которого входят в состав активного центра протеина А, обеспечивающего его связывание с Fc-фрагментом иммуноглобулинов класса G. Активность данного тетрапеп-тида подтверждена исследованиями аффинности связывания с Fc-фрагментом иммуноглобулинов класса G
Разработка гемосорбентов для связывания IgG на основе олигопептидных лигандов
Get PDFThe possibility for development of new hemosorbents based on oligopeptide analogues of Staphylococcus aureus protein A epitopes and polyethylene matrix, is discussed. A convenient method for hemosorbent preparation has been developed and primary tests have been performed.Рассматривается возможность создания новых гемосорбентов на основе олигопептидных аналогов эпитопов протеина А Staphylococcus aureus и полиэтиленовой матрицы. Предложена удобная методика получения гемосор-бентов и проведены первичные экспериментальные испытания
Unexpected products from the reaction of the synthetic cross-linker 3,3′-dithiobis(sulfosuccinimidyl propionate), DTSSP with peptides
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Nonparametric algorithms of pattern recognition in the problem of testing a statistical hypothesis on identity of two distribution laws of random variables
No full textNonparametric Algorithm of Identification of Classes Corresponding to Single-mode Fragments of the Probability Density of Multidimensional Random Variables
No full textGeneration of polarized gamma-quanta by relativtstic electrons interacted with an atomic string in a crystal
No full textyesBSUThis work is devoted to theoretical research of two coherent mechanisms of linear polarized photon emission by relativostic electrons interacting with the single atomic string of a crysta
Generation of polarized gamma-quanta by relativtstic electrons interacted with an atomic string in a crystal
No full textThis work is devoted to theoretical research of two coherent mechanisms of linear polarized photon emission by relativostic electrons interacting with the single atomic string of a crysta
Generation of polarized gamma-quanta by relativtstic electrons interacted with an atomic string in a crystal
No full textThis work is devoted to theoretical research of two coherent mechanisms of linear polarized photon emission by relativostic electrons interacting with the single atomic string of a crystalyesBS
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