113 research outputs found
Thermodynamic aspects of materials' hardness: prediction of novel superhard high-pressure phases
In the present work we have proposed the method that allows one to easily
estimate hardness and bulk modulus of known or hypothetical solid phases from
the data on Gibbs energy of atomization of the elements and corresponding
covalent radii. It has been shown that hardness and bulk moduli of compounds
strongly correlate with their thermodynamic and structural properties. The
proposed method may be used for a large number of compounds with various types
of chemical bonding and structures; moreover, the temperature dependence of
hardness may be calculated, that has been performed for diamond and cubic boron
nitride. The correctness of this approach has been shown for the recently
synthesized superhard diamond-like BC5. It has been predicted that the
hypothetical forms of B2O3, diamond-like boron, BCx and COx, which could be
synthesized at high pressures and temperatures, should have extreme hardness
Approaches of Russian oil companies to optimal capital structure
Oil companies play a vital role in Russian economy. Demand for hydrocarbon products will be increasing for the nearest decades simultaneously with the population growth and social needs. Change of raw-material orientation of Russian economy and the transition to the innovative way of the development do not exclude the development of oil industry in future. Moreover, society believes that this sector must bring the Russian economy on to the road of innovative development due to neo-industrialization. To achieve this, the government power as well as capital management of companies are required. To make their optimal capital structure, it is necessary to minimize the capital cost, decrease definite risks under existing limits, and maximize profitability. The capital structure analysis of Russian and foreign oil companies shows different approaches, reasons, as well as conditions and, consequently, equity capital and debt capital relationship and their cost, which demands the effective capital management strategy
Digital receivers for low-frequency radio telescopes UTR-2, URAN, GURT
This paper describes digital radio astronomical receivers used for decameter
and meter wavelength observations. This paper describes digital radio
astronomical receivers used for decameter and meter wavelength observations.
Since 1998, digital receivers performing on-the-fly dynamic spectrum
calculations or waveform data recording without data loss have been used at the
UTR-2 radio telescope, the URAN VLBI system, and the GURT new generation radio
telescope. Here we detail these receivers developed for operation in the strong
interference environment that prevails in the decameter wavelength range. Data
collected with these receivers allowed us to discover numerous radio
astronomical objects and phenomena at low frequencies, a summary of which is
also presented.Comment: 24 pages, 15 figure
НАЛЕЖНА ОРГАНІЗАЦІЯ АТЕСТАЦІЇ ВИПУСКНИКІВ – ВАЖЛИВА СКЛАДОВА РЕАЛІЗАЦІЇ ЗАКОНУ УКРАЇНИ “ПРО ВИЩУ ОСВІТУ”
The article presents the principles and features of certification of graduates of Ukrainian medical and pharmaceutical universities in 2016.У статті наведено принципи та особливості проведення атестації випускників українських вищих медичних та фармацевтичних навчальних закладів у 2016 р
Особенности клинической манифестации первичной открытоугольной глаукомы у пациентов с наследственно отягощенным анамнезом заболевания
This review describes currently most well-known research findings dedicated to the specific features of manifestation and course of primary open-angle glaucoma with hereditary tainted history. Despite the fact that aggravated heredity has been confirmed as a risk factor for primary open-angle glaucoma (POAG), the information on the clinical features and progression patterns of POAG in patients with hereditary predisposition presented in the existing publications is scattered, and its availability is still limited by the amount of included material. All of this, in turn, makes it impossible to fully predict the course of the disease and to discuss the possibility of its earlier detection in that population group. The discussion presented in this work points out the type of kinship for which the risk of developing glaucoma is most relevant, as well as the supposed characteristics of the age of onset of POAG among patients with a family history of this disease. The results of the studies analyzed in this review can help actualize the viewpoint on the possible differences in clinical manifestations of the disease in patients with hereditary (familial) and sporadic forms of glaucoma, as well as on the necessity of further clinical research in this area.В данном обзоре рассмотрены наиболее известные на данный момент результаты исследований, посвященных особенностям проявления и течения первичной открытоугольной глаукомы (ПОУГ) с наследственно отягощенным анамнезом заболевания. Несмотря на то, что факт отягощенной наследственности как риска развития ПОУГ подтвержден, информация о клинических особенностях и характере прогрессирования ПОУГ у пациентов с наследственной предрасположенностью, представленной в современных публикациях, носит разрозненный характер, а их доступность все еще ограничена числом включенного материала. Все это, в свою очередь, не позволяет в полной мере строить прогнозы течения болезни и обсуждать возможности более раннего обнаружения заболевания среди этой группы населения.Обсуждение, представленное в публикации, позволило отметить характер родства, для которого риск развития глаукомы наиболее актуален, а также предполагаемые характеристики возраста проявления заболевания ПОУГ среди пациентов с наличием семейного анамнеза. Результаты работ, представленных в данном обзоре, дают возможность актуализировать позицию о наличии различий клинической манифестации заболевания у пациентов с наследственной (семейной) и спорадической формами глаукомы, а также о необходимости дальнейших клинических исследований в этой области
Наследственная моторно-сенсорная нейропатия, обусловленная мутацией в гене NEFL, в семье из Карачаево-Черкессии
The clinical and genetic features of hereditary motor and sensory neuropathy (HMSN; Charcot–Marie–Tooth disease, CMT) caused by newly identified missense mutation s.65G>T (p.Pro22His) in NEFL gene located on the chromosome 8р21.2 are described. The disease was diagnosed in a large family from Ust-Dzhegutinsky district of the Karachay-Cherkess Republic with the segregation of the disease in four generations. The prevalence of the HMSN in that district was found to be 1:4340 persons, including 1:3376 among Karachays. The clinical picture of the disease was characterized by onset at the age of 11–14 years, weakness in foot muscles and steppage gait. The specific features in the majority of patients were the absence of major sensory disturbances, as well as long-term preserved distal arm muscles. Nerve conduction velocity in the median nerve varied from 30 to 42 m/s, which corresponds to values in patients with CMT2E, previously described.В статье описаны клинико-генетические характеристики наследственной моторно-сенсорной нейропатии (НМСН, болезнь Шарко–Мари–Тута, БШМТ), обусловленной вновь выявленной миссенс-мутацией с.65G>T (p.Pro22His) в гене NEFL на хромосоме 8р21.2, у больных из семьи, проживающей в Усть-Джегутинском районе Карачаево-Черкесской Республики, с сегрегацией заболевания в 4 поколениях. Распространенность НМСН в обследованном районе составила 1:4340 человек, в том числе 1:3376 среди карачаевцев. Заболевание манифестировало в возрасте 11–14 лет с появления слабости стоп и формирования степпажной походки. Особенности клинических проявлений – отсутствие значимых расстройств чувствительности у большинства обследованных больных и длительная сохранность мышц дистальных отделов рук. Показатели скорости распространения возбуждения по срединному нерву колебались от 30 до 42 м/с, что соответствовало таковым у пациентов с БШМТ типа 2Е, описанным ранее
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