On five-dimensional non-extremal charged black holes and FRW cosmology

We consider static non-extremal charged black hole solutions in the context of N=2 gauged supergravity theories in five dimensions, and we show that they satisfy first-order flow equations. Then we analyze the motion of the dual brane in these black hole backgrounds. We express the entropy in terms of a Cardy-Verlinde-type formula, and we show that the equations describing the FRW cosmology on the brane have a form that is similar to the equations for the entropy and for the Casimir energy on the brane. We also briefly comment on the inclusion of a Gauss-Bonnet term in the analysis.Comment: 27 pages,5 figures, references adde

On Subextensive Corrections to Fluid Dynamics from Gravity

We use the fluid-gravity correspondence to compute subextensive corrections, proportional to the shear tensor, to the energy-momentum tensor of fluids on three-spheres. The dual configurations we consider are charged black hole solutions of N = 2 gauged supergravity theories in five dimensions.Comment: 26 pages, LaTeX, added comment

EOS: A project to investigate the design and construction of real-time distributed embedded operating systems

The EOS project is investigating the design and construction of a family of real-time distributed embedded operating systems for reliable, distributed aerospace applications. Using the real-time programming techniques developed in co-operation with NASA in earlier research, the project staff is building a kernel for a multiple processor networked system. The first six months of the grant included a study of scheduling in an object-oriented system, the design philosophy of the kernel, and the architectural overview of the operating system. In this report, the operating system and kernel concepts are described. An environment for the experiments has been built and several of the key concepts of the system have been prototyped. The kernel and operating system is intended to support future experimental studies in multiprocessing, load-balancing, routing, software fault-tolerance, distributed data base design, and real-time processing

Impact of weekday surgery on application of enhanced recovery pathway: a retrospective cohort study.

To compare the enhanced recovery after surgery (ERAS) protocol compliance and clinical outcomes depending on the weekday of surgery. Cohort of consecutive non-selected patients undergoing elective colorectal surgery from January 2012 to March 2015. This retrospective analysis of our prospective database compared patients operated early in the week (Monday and Tuesday) with patients operated in the second half (late: Thursday, Friday). Compliance with the ERAS protocol, functional recovery, complications and length of stay. Demographic and surgical details were similar between the early (n=352) and late groups (n=204). Overall compliance with the ERAS protocol was 78% vs 76% for the early and late groups, respectively (p=0.009). Significant differences were notably prolonged urinary drainage and intravenous fluid infusion in the late group. Complication rates and length of stay, however, were not different between surgery on Monday or Tuesday and surgery on Thursday or Friday. Application of the ERAS protocol showed only minor differences for patients operated on early or late during the week, and clinical outcomes were similar. A fully implemented ERAS programme appears to work also over the weekend

In-line filter included into the syringe infusion pump assembly reduces flow irregularities

Purpose: To evaluate whether an in-line filter inserted in the syringe pump infusion line assembly influences start-up times and flow irregularities during vertical pump displacement at low infusion rates. Methods: Fluid delivery after syringe pump start-up and after vertical displacement of the syringe pump by −50cm was determined gravimetrically at flow rates of 0.5, 1.0 and 2.0mlh−1. Measurements were repeated for each flow rate four times with two different syringe pumps with and without an in-line filter incorporated. Data are shown as median and range. Results: Start-up times were reduced by an in-line filter at 0.5mlh−1 flow rate from 355.5s (0-660) to 115s (0-320), whereas the effect was attenuated at higher flow rates. Pooling of fluid into the infusion system after lowering the infusion syringe pump was halved in all flow rates tested. Amount of infusion bolus after elevating the syringe pump by 50cm was not affected by an in-line filter. Conclusion: In the evaluated model in-line filters help to reduce flow irregularities and delay in drug delivery of syringe pumps at low flow rates and represent an option to optimize continuous administration of highly concentrated short-acting drugs at very small infusion rate

PECULIARITIES OF ECONOMIC SOCIALIZATION OF SCHOOL STUDENTS IN RUSSIA AND CHINA

Different countries have started to recognize the importance of economic socialization of youth. The article describes how Russia and China at the state level encourage school students to be economically socialized. The article describes peculiarities of economic socialization of school students in Russia and China. The attention is paid to secondary schools in both countries which play a great role in economic socialization of school students. The article highlights the common features and differences of the economic socialization of school students in Russia and in China. It is shown that the common features of this kind of socialization in both countries are the following. Russia and China respect the importance of economic socialization of school students. They introduce a variety of measures into real life: organize special entrepreneurial theoretical trainings in schools, deliver lectures, workshops, discuss money and financial issues. As for the differences, they are as follows. In Russia school students are more theoretically oriented in terms of economics and entrepreneurship. Chinese school students have more practical training because most of schools in China have mini-enterprises in forms of farms, restaurants and etc. In other words, school students obtain practical knowledge and skills of economics on the business sites

A Dissipative-Particle-Dynamics Model for Simulating Dynamics of Charged Colloid

A mesoscopic colloid model is developed in which a spherical colloid is represented by many interacting sites on its surface. The hydrodynamic interactions with thermal fluctuations are taken accounts in full using Dissipative Particle Dynamics, and the electrostatic interactions are simulated using Particle-Particle-Particle Mesh method. This new model is applied to investigate the electrophoretic mobility of a charged colloid under an external electric field, and the influence of salt concentration and colloid charge are systematically studied. The simulation results show good agreement with predictions from the electrokinetic theory.Comment: 17 pages, 8 figures, submitted to the proceedings of High Performance Computing in Science & Engineering '1

Sustainability and long-term strategies in the modeling of biological processes

In this article, we intend to explore the role of using an”infinite time horizon” framework to address the issues of sustainability and long-term strategies in the control of biological processes. We use two case study models to explain why considering a fixed or moving endpoint does not lead to the desired long-term effects. The first biological model considered concerns the spread of an infectious disease and its treatment as an infinite horizon optimal control problem. The second one deals with the metronomic chemotherapy cancer treatment over the remaining lifetime horizon of the patient. The latter is consistent with the conception of cancer as a chronic disease. Both models show structural differences in the choice of the objective functional, the first one uses a stabilization functional containing a weight function, the second one contains a damage functional which involves a density function

Pressurised intraperitoneal aerosol chemotherapy: rationale, evidence, and potential indications.

Pressurised intraperitoneal aerosol chemotherapy (PIPAC) was introduced as a new treatment for patients with peritoneal metastases in November, 2011. Reports of its feasibility, tolerance, and efficacy have encouraged centres worldwide to adopt PIPAC as a novel drug delivery technique. In this Review, we detail the technique and rationale of PIPAC and critically assess its evidence and potential indications. A systematic search was done to identify all relevant literature on PIPAC published between Jan 1, 2011, and Jan 31, 2019. A total of 106 articles or reports on PIPAC were identified, and 45 clinical studies on 1810 PIPAC procedures in 838 patients were included for analysis. Repeated PIPAC delivery was feasible in 64% of patients with few intraoperative and postoperative surgical complications (3% for each in prospective studies). Adverse events (Common Terminology Criteria for Adverse Events greater than grade 2) occurred after 12-15% of procedures, and commonly included bowel obstruction, bleeding, and abdominal pain. Repeated PIPAC did not have a negative effect on quality of life. Using PIPAC, an objective clinical response of 62-88% was reported for patients with ovarian cancer (median survival of 11-14 months), 50-91% for gastric cancer (median survival of 8-15 months), 71-86% for colorectal cancer (median survival of 16 months), and 67-75% (median survival of 27 months) for peritoneal mesothelioma. From our findings, PIPAC has been shown to be feasible and safe. Data on objective response and quality of life were encouraging. Therefore, PIPAC can be considered as a treatment option for refractory, isolated peritoneal metastasis of various origins. However, its use in further indications needs to be validated by prospective studies