582 research outputs found
Current oscillations in a metallic ring threaded by a time-dependent magnetic flux
We study a mesoscopic metallic ring threaded by a magnetic flux which varies
linearly in time PhiM(t)=Phi t with a formalism based in Baym-Kadanoff-Keldysh
non-equilibrium Green functions. We propose a method to calculate the Green
functions in real space and we consider an experimental setup to investigate
the dynamics of the ring by recourse to a transport experiment. This consists
in a single lead connecting the ring to a particle reservoir. We show that
different dynamical regimes are attained depending on the ratio hbar Phi/Phi0
W, being Phi0=h c/e and W, the bandwidth of the ring. For moderate lengths of
the ring, a stationary regime is achieved for hbar Phi/Phi0 >W. In the opposite
case with hbar Phi/Phi0 < W, the effect of Bloch oscillations driven by the
induced electric field manifests itself in the transport properties of the
system. In particular, we show that in this time-dependent regime a tunneling
current oscillating in time with a period tau=2piPhi0/Phi can be measured in
the lead. We also analyze the resistive effect introduced by inelastic
scattering due to the coupling to the external reservoir.Comment: 17 pages, 13 figure
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Computational framework for longevity risk management
Longevity risk threatens the financial stability of private and government sponsored defined benefit pension systems as well as social security schemes, in an environment already characterized by persistent low interest rates and heightened financial uncertainty. The mortality experience of countries in the industrialized world would suggest a substantial age-time interaction, with the two dominant trends affecting different age groups at different times. From a statistical point of view, this indicates a dependence structure. It is observed that mortality improvements are similar for individuals of contiguous ages (Wills and Sherris, Integrating financial and demographic longevity risk models: an Australian model for financial applications, Discussion Paper PI-0817, 2008). Moreover, considering the dataset by single ages, the correlations between the residuals for adjacent age groups tend to be high (as noted in Denton et al., J Population Econ 18:203-227, 2005). This suggests that there is value in exploring the dependence structure, also across time, in other words the inter-period correlation. In this research, we focus on the projections of mortality rates, contravening the most commonly encountered dependence property which is the "lack of dependence" (Denuit et al., Actuarial theory for dependent risks: measures. Orders and models, Wiley, New York, 2005). By taking into account the presence of dependence across age and time which leads to systematic over-estimation or under-estimation of uncertainty in the estimates (Liu and Braun, J Probability Stat, 813583:15, 2010), the paper analyzes a tailor-made bootstrap methodology for capturing the spatial dependence in deriving confidence intervals for mortality projection rates. We propose a method which leads to a prudent measure of longevity risk, avoiding the structural incompleteness of the ordinary simulation bootstrap methodology which involves the assumption of independence
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Frailty-based LeeâCarter family of stochastic mortality models
In the actuarial literature, frailty is defined to be the unobserved variable which encompasses all the factors affecting human mortality other than gender and age. Heterogeneity in individual frailty can play a significant role in population mortality dynamics. In the present paper, we identify the main latent factors that explain the frailty component, in order to clarify its role in mortality projections. We show, using longitudinal survey data, that frailty is mainly due to co-morbidities that impact on the process of deterioration in terms of the human bodyâs physiological capacity. Accordingly, we provide frailty-based stochastic models for projecting mortality based on the LeeâCarter family of models. We propose several versions that consider frailty both as an age-dependent and a time-dependent factor and also combining the interaction effects of age and time in comparison with the general level of mortality, and compare the resulting mortality projections using data from England
Tuning a Resonance in the Fock Space: Optimization of Phonon Emission in a Resonant Tunneling Device
Phonon-assisted tunneling in a double barrier resonant tunneling device can
be seen as a resonance in the electron-phonon Fock space which is tuned by the
applied voltage. We show that the geometrical parameters can induce a symmetry
condition in this space that can strongly enhance the emission of longitudinal
optical phonons. For devices with thin emitter barriers this is achieved by a
wider collector's barrier.Comment: 4 pages, 3 figures. Figure 1 changed, typos correcte
Accuracy of a method based on atomic absorption spectrometry to determine inorganic arsenic in food : Outcome of the collaborative trial IMEP-41
Peer reviewedPublisher PD
Approximate Analytical Model for the Squeeze-Film Lubrication of the Human Ankle Joint with Synovial Fluid Filtrated by Articular Cartilage
The aim of this article is to propose an analytical approximate squeeze-film lubrication model of the human ankle joint for a quick assessment of the synovial pressure field and the load carrying due to the squeeze motion. The model starts from the theory of boosted lubrication for the human articular joints lubrication (Walker et al., Rheum Dis 27:512â520, 1968; Maroudas, Lubrication and wear in joints. Sector, London, 1969) and takes into account the fluid transport across the articular cartilage using Darcyâs equation to depict the synovial fluid motion through a porous cartilage matrix. The human ankle joint is assumed to be cylindrical enabling motion in the sagittal plane only. The proposed model is based on a modified Reynolds equation; its integration allows to obtain a quick assessment on the synovial pressure field showing a good agreement with those obtained numerically (Hlavacek, J Biomech 33:1415â1422, 2000). The analytical integration allows the closed form description of the synovial fluid film force and the calculation of the unsteady gap thickness
Time evolution of stimulated Raman scattering and two-plasmon decay at laser intensities relevant for shock ignition in a hot plasma
Laserâplasma interaction (LPI) at intensities 1015â1016 W cm2 is dominated by parametric instabilities which can be
responsible for a significant amount of non-collisional absorption and generate large fluxes of high-energy nonthermal
electrons. Such a regime is of paramount importance for inertial confinement fusion (ICF) and in particular for the
shock ignition scheme. In this paper we report on an experiment carried out at the Prague Asterix Laser System (PALS)
facility to investigate the extent and time history of stimulated Raman scattering (SRS) and two-plasmon decay (TPD)
instabilities, driven by the interaction of an infrared laser pulse at an intensity 1:2 1016 W cm2 with a 100 mm
scalelength plasma produced from irradiation of a flat plastic target. The laser pulse duration (300 ps) and the high
value of plasma temperature (4 keV) expected from hydrodynamic simulations make these results interesting for a
deeper understanding of LPI in shock ignition conditions. Experimental results show that absolute TPD/SRS, driven at
a quarter of the critical density, and convective SRS, driven at lower plasma densities, are well separated in time, with
absolute instabilities driven at early times of interaction and convective backward SRS emerging at the laser peak and
persisting all over the tail of the pulse. Side-scattering SRS, driven at low plasma densities, is also clearly observed.
Experimental results are compared to fully kinetic large-scale, two-dimensional simulations. Particle-in-cell results,
beyond reproducing the framework delineated by the experimental measurements, reveal the importance of filamentation
instability in ruling the onset of SRS and stimulated Brillouin scattering instabilities and confirm the crucial role of
collisionless absorption in the LPI energy balance
Kondo resonances and Fano antiresonances in transport through quantum dots
The transmission of electrons through a non-interacting tight-binding chain
with an interacting side quantum dot (QD) is analized. When the Kondo effect
develops at the dot the conductance presents a wide minimum, reaching zero at
the unitary limit. This result is compared to the opposite behaviour found in
an embedded QD. Application of a magnetic field destroys the Kondo effect and
the conductance shows pairs of dips separated by the charging energy U. The
results are discussed in terms of Fano antiresonances and explain qualitatively
recent experimental results.Comment: 4 pages including 4 figure
Effect of aspirin on the diagnostic accuracy of the faecal immunochemical test for colorectal advanced neoplasia
Background: Aspirin (ASA) is a drug that can cause gastrointestinal lesions and symptoms. Colorectal cancer (CRC) is the most prevalent type of cancer in Western countries. We assessed the effect of aspirin on the diagnostic accuracy of the faecal immunochemical test (FIT) for CRC and/or advanced neoplasia (AN) in patients undergoing colonoscopy for gastrointestinal symptoms.
Methods: We conducted a prospective multicentre observational study of diagnostic tests that included patients with gastrointestinal symptoms undergoing colonoscopy between March 2012 and 2014 (the COLONPREDICT study). Symptoms were assessed and a FIT and blood tests assessing haemoglobin and carcinoembryonic antigen (CEA) levels were performed.
Results: The study included 3052 patients: A total of 2567 did not take aspirin (non-user group) and 485 (16%) took aspirin (user group). Continuous treatment with ASA did not change the AUC (0.88, 0.82; p = 0.06), sensitivity (92%, 88%; p = 0.5) or specificity (71%, 67%; p = 0.2) of the FIT for CRC detection. Similarly, we found no differences in the AUC (0.81, 0.79; p = 0.6), sensitivity (74%, 75.5%; p = 0.3) or specificity (76%, 73.6%; p = 0.3) for AN detection. Patients with an aspirin use of = 300 mg/day had a lower prevalence of AN and the sensitivity, specificity and AUC for AN for these patients were 54%, 68% and 0.66, significantly lower than for the non-user group (p = 0.03).
Conclusions: Aspirin does not modify the diagnostic accuracy of FIT for CRC and/or AN in patients with gastrointestinal symptoms. Aspirin use of = 300 mg/day decreases the accuracy of the test
Conductance and persistent current of a quantum ring coupled to a quantum wire under external fields
The electronic transport of a noninteracting quantum ring side-coupled to a
quantum wire is studied via a single-band tunneling tight-binding Hamiltonian.
We found that the system develops an oscillating band with antiresonances and
resonances arising from the hybridization of the quasibound levels of the ring
and the coupling to the quantum wire. The positions of the antiresonances
correspond exactly to the electronic spectrum of the isolated ring. Moreover,
for a uniform quantum ring the conductance and the persistent current density
were found to exhibit a particular odd-even parity related with the ring-order.
The effects of an in-plane electric field was also studied. This field shifts
the electronic spectrum and damps the amplitude of the persistent current
density. These features may be used to control externally the energy spectra
and the amplitude of the persistent current.Comment: Revised version, 7 pages and 9 figures. To appear in Phys. Rev.
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