Asymptotical photon distributions in the dissipative Dynamical Casimir Effect

Asymptotical formulas for the photon distribution function of a quantum oscillator with time-dependent frequency and damping coefficients, interacting with a thermal reservoir, are derived in the case of a large mean number of quanta. Different regimes of excitation of an initial thermal state with an arbitrary temperature are considered. New formulas are used to predict the statistical properties of the electromagnetic field created in the experiments on the Dynamical Casimir Effect which are now under preparation.Comment: 11 pages, accepted contribution to CEWQO 2009 proceedings (to appear in Physica Scripta

Geomorphology of the urban area of Palermo (Italy)

The results of a geomorphological study carried out in the urban area of Palermo are summarized in a thematic map. Field survey, analysis of aerial photographs and topographic maps, consultation of historical documents and maps, stratigraphic and topographic reconstruction from numerous wells and subsoil data, and bibliographic search were performed, in order to display the geomorphological changes produced by man over time in a densely populated area and to define the Anthropocene of the study area. Palermo town rises along large marine terrace surfaces cut by small river valleys and bordered by wide degraded and abandoned coastal cliffs. Over the last 2700 years, this area was affected by remarkable man-made changes to topographic surface and underground, exposing large areas of the city to hydraulic, sinkhole, and landslide risks, and increasing the levels of seismic susceptibility. In light of these results, the produced map is useful for urban planning studies

Photon creation from vacuum and interactions engineering in nonstationary circuit QED

We study theoretically the nonstationary circuit QED system in which the artificial atom transition frequency, or the atom-cavity coupling, have a small periodic time modulation, prescribed externally. The system formed by the atom coupled to a single cavity mode is described by the Rabi Hamiltonian. We show that, in the dispersive regime, when the modulation periodicity is tuned to the `resonances', the system dynamics presents the dynamical Casimir effect, resonant Jaynes-Cummings or resonant Anti-Jaynes-Cummings behaviors, and it can be described by the corresponding effective Hamiltonians. In the resonant atom-cavity regime and under the resonant modulation, the dynamics is similar to the one occurring for a stationary two-level atom in a vibrating cavity, and an entangled state with two photons can be created from vacuum. Moreover, we consider the situation in which the atom-cavity coupling, the atomic frequency, or both have a small nonperiodic time modulation, and show that photons can be created from vacuum in the dispersive regime. Therefore, an analog of the dynamical Casimir effect can be simulated in circuit QED, and several photons, as well as entangled states, can be generated from vacuum due to the anti-rotating term in the Rabi Hamiltonian.Comment: 14 pages, 6 figures. Talk presented at the International Workshop "60 Years of Casimir Effect", 23 - 27 June, 2008, Brasili

Geositi nel paesaggio mediterraneo: confronto tra aree costiere maltesi e siciliane.

Le isole maltesi mostrano aspetti geologici, geomorfologici e ambientali comparabili con quelli siciliani che danno luogo alla presenza di elementi paesaggistici ad elevata potenzialit\ue0 turistica, ad oggi non sufficientemente valorizzati. Nell\u2019ambito di un progetto di ricerca internazionale volto alla realizzazione di reti ecologiche transfrontaliere Malta-Sicilia (RE.MA.SI.), sono stati condotti studi sulla valorizzazione, divulgazione e corretta fruizione del patrimonio geologico di alcuni territori di queste due isole. Vengono qui presentati i risultati preliminari che hanno portato all'identificazione e valorizzazione di geositi di interesse geomorfologico, le cui caratteristiche sono state analizzate qualitativamente e quantitativamente, tramite l\u2019applicazione di metodologie gi\ue0 sperimentate a livello internazionale e basate sulla stima del loro valore scientifico, addizionale e di fruibilit\ue0. Sono state analizzate principalmente forme di rilevante interesse scientifico, didattico e paesaggistico, quali morfotipi costieri, evidenze morfologiche di processi gravitativi e di erosione idrica e forme carsiche

Cardiovascular Response to Intraneural Right Vagus Nerve Stimulation in Adult Minipig.

Objective: This study explored intraneural stimulation of the right thoracic vagus nerve (VN) in sexually mature male minipigs to modulate safe heart rate and blood pressure response. Material and methods: We employed an intraneural electrode designed for the VN of pigs to perform VN stimulation (VNS). This was delivered using different numbers of contacts on the electrode and different stimulation parameters (amplitude, frequency, and pulse width), identifying the most suitable stimulation configuration. All the parameter ranges had been selected from a computational cardiovascular system model. Results: Clinically relevant responses were observed when stimulating with low current intensities and relatively low frequencies delivered with a single contact. Selecting a biphasic, charge-balanced square wave for VNS with a current amplitude of 500 μA, frequency of 10 Hz, and pulse width of 200 μs, we obtained heart rate reduction of 7.67 ± 5.19 beats per minute, systolic pressure reduction of 5.75 ± 2.59 mmHg, and diastolic pressure reduction of 3.39 ± 1.44 mmHg. Conclusion: Heart rate modulation was obtained without inducing any observable adverse effects, underlining the high selectivity of the intraneural approach

Exercise intolerance at high altitude (5050 m): critical power and W'

The relationship between work rate (WR) and its tolerable duration (t(LIM)) has not been investigated at high altitude (HA). At HA (5050 m) and at sea level (SL), six subjects therefore performed symptom-limited cycle-ergometry: an incremental test (IET) and three constant-WR tests (% of IET WR(max), HA and SL respectively: WR(1) 70±8%, 74±7%; WR(2) 86±14%, 88±10%; WR(3) 105±13%, 104±9%). The power asymptote (CP) and curvature constant (W') of the hyperbolic WR-t(LIM) relationship were reduced at HA compared to SL (CP: 81±21 vs. 123±38 W; W': 7.2±2.9 vs. 13.1±4.3 kJ). HA breathing reserve (estimated maximum voluntary ventilation minus end-exercise ventilation) was also compromised (WR(1): 25±25 vs. 50±18 l min(-1); WR(2): 4±23 vs. 38±23 l min(-1); WR(3): -3±18 vs. 32±24 l min(-1)) with near-maximal dyspnea levels (Borg) (WR(1): 7.2±1.2 vs. 4.8±1.3; WR(2): 8.8±0.8 vs. 5.3±1.2; WR(3): 9.3±1.0 vs. 5.3±1.5). The CP reduction is consistent with a reduced O(2) availability; that of W' with reduced muscle-venous O(2) storage, exacerbated by ventilatory limitation and dyspnea. Copyright © 2011 Elsevier B.V. All rights reserved

A multi-scale regional landslide susceptibility assessment approach: the SUFRA_SICILIA (SUscettibilit\ue0 da FRAna in Sicilia) project

The SUFRA project is based on a three level susceptibility mapping. According to the availability of more detailed data, the three scale for susceptibility mapping are increased respect to the ones suggested by the TIER group to 1:100,000, 1:50,000 and 1:25,000/1:10,000. The mapping levels exploit climatic, soil use (CORINE2009) and seismic informative layers, differentiating in the details of the core data (geology and topography), in the quality and resolution of the landslide inventory and in the modelling approach (Tab. 1). SUFRA_100 is based on a heuristic approach which is applied by processing a geologic layer (produced by ARTA integrating pre-CARG 1:100,000 geologic maps); the DEM exploited are IGMI 250m and the mapping units are 1km side square cells. Models are validated with respect to the PAI LIPs (Landslide Identification Points) which are reclassified adopting a simplified scheme. Output cuts of SUFRA100 will be referred to administrative boundaries (provinces). SUFRA50 is based on statistical analysis of new CARG geologic maps and 20m (ITA2000) - 2m (ATA2007) DEM. The mapping units are 500m and 50m cells, hydrographic and hydro-morphometric units. The landslide inventory is the IFFI2012_LIPs (first level) which is the result of the conversion in IFFI format of the PAI archive, which will be supported by remote landslide mapping (exploiting the ATA2007 aerial photos), according to the IFFI first level approach. Validation of the models will be performed exploiting both random spatial partition and temporal partition methods. Output cuts of SUFRA50 will be based on physiographic (basin) and administrative (municipalities) boundaries. SUFRA10/25 is based on statistical analysis of new CARG geologic maps (remotely and field adapted) and 2m (ATA2007) DEM. The mapping units are the slope units (SLUs) which are derived by further partitioning the hydro-morphometric units so to obtain closed morphodynamic units. The landslide inventories is the IFFI2012 which is the results of a field supported (on focus) landslide remote systematic mapping, according to the IFFI full level approach. Examples of SUFRA_100, SUFRA_50 and SUFRA_10 are presented for some representative key sector of Sicily. First results attest for the feasibility and goodness of the proposed protocol. The SUFRA program aims at enabling the regional governmental administration to cope with landslide prevision, which is the required operational concept in land management and planning. PAI has been a great advance with respect to the \u201cpre-SARNO\u201d conditions, but it is very exposed to fail: it is a blind approach for new activations; it is critically dependent on the quality of the landslide inventories; it cannot project the susceptibility outside the landslide area

Neural Stimulation Hardware for the Selective Intrafascicular Modulation of the Vagus Nerve

The neural stimulation of the vagus nerve is able to modulate various functions of the parasympathetic response in different organs. The stimulation of the vagus nerve is a promising approach to treating inflammatory diseases, obesity, diabetes, heart failure, and hypertension. The complexity of the vagus nerve requires highly selective stimulation, allowing the modulation of target-specific organs without side effects. Here, we address this issue by adapting a neural stimulator and developing an intraneural electrode for the particular modulation of the vagus nerve. The neurostimulator parameters such as amplitude, pulse width, and pulse shape were modulated. Single-, and multi-channel stimulation was performed at different amplitudes. For the first time, a polyimide thin-film neural electrode was designed for the specific stimulation of the vagus nerve. In vivo experiments were performed in the adult minipig to validate to elicit electrically evoked action potentials and to modulate physiological functions, validating the spatial selectivity of intraneural stimulation. Electrochemical tests of the electrode and the neurostimulator showed that the stimulation hardware was working correctly. Stimulating the porcine vagus nerve resulted in spatially selective modulation of the vagus nerve. ECAP belonging to alpha and beta fibers could be distinguished during single- and multi-channel stimulation. We have shown that the here presented system is able to activate the vagus nerve and can therefore modulate the heart rate, diastolic pressure, and systolic pressure. The here presented system may be used to restore the cardiac loop after denervation by implementing biomimetic stimulation patterns. Presented methods may be used to develop intraneural electrodes adapted for various applications

Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period

The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive measurements even if, in the latest years, invasive microelectromechanical systems (MEMS) sensors have emerged as a valuable approach for precise and continuous monitoring of cardiac activity. The main challenges in designing cardiac MEMS sensors are represented by miniaturization, biocompatibility, and long-term stability. Here, we present a MEMS piezoresistive cardiac sensor capable of continuous monitoring of LV activity over time following epicardial implantation with a pericardial patch graft in adult minipigs. In acute and chronic scenarios, the sensor was able to compute heart rate with a root mean square error lower than 2 BPM. Early after up to 1 month of implantation, the device was able to record the heart activity during the most important phases of the cardiac cycle (systole and diastole peaks). The sensor signal waveform, in addition, closely reflected the typical waveforms of pressure signal obtained via intraventricular catheters, offering a safer alternative to heart catheterization. Furthermore, histological analysis of the LV implantation site following sensor retrieval revealed no evidence of myocardial fibrosis. Our results suggest that the epicardial LV implantation of an MEMS sensor is a suitable and reliable approach for direct continuous monitoring of cardiac activity. This work envisions the use of this sensor as a cardiac sensing device in closed-loop applications for patients undergoing heart surgery