Laser monitoring system for the CMS lead tungstate crystal calorimeter

We report on the multiple wavelength laser monitoring system designed for the CMS lead tungstate crystal calorimeter read-out with avalanche photodiodes (Barrel calorimeters) and vacuum phototriodes (End Cap calorimeters). Results are presented for the test beam performance of the system designed to achieve 0.5% relative inter-calibration of the optical transmittance for lead tungstate scintillation emission over nearly 80 000 channels. The system operates in continuous measurement cycles to follow each crystal?s evolution under irradiation and recovery periods foreseen during operation at the LHC

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Interactions sociales et appropriation de stratégies par l'enfant pour résoudre un problème : quelles méthodes ?

Cette recherche s’inscrit dans une série de travaux recourant à une méthodologie alliant l’approche clinique piagétienne, expérimentale dans des situations différentes, et vygots-kienne, afin de mettre en évidence les processus par lesquels l’appropriation de stratégies par l’enfant sera possible par l’observation attentive de son histoire d’apprentissage et afin de comprendre un peu mieux les conditions de la mobilisation ultérieure de ces apprentissages. La méthode utilisée consiste à placer les enfants dans trois ou quatre contextes différents, à observer leurs interactions et leurs conduites cognitives, notamment en fonction de leur niveau d’expertise initial par rapport à une tâche donnée : une phase I de prétest, permettant d’apprécier le niveau initial de chaque enfant en interaction avec un adulte testeur, les enfants sont alors classés en «novices», «experts spontanés», une phase II de formation (selon des modalités qui varient) avec un adulte pour une partie des enfants novices qui deviendront ainsi des «experts formés», puis une phase III d’interaction entre «novice» et «expert» (soit spontané soit formé) et, enfin, une dernière phase IV «post-test», identique au pré-test.Tartas Valérie, Perret-Clermont Anne Nelly, Marro Pascale, Grossen Michèle. Interactions sociales et appropriation de stratégies par l’enfant pour résoudre un problème : quelles méthodes ?. In: Bulletin de psychologie, tome 57 n°469, 2004. Développement, fonctionnement : perspective historico-culturelle. pp. 111-115

Curative treatment can be an option for patients with metastatic squamous cell cancer of the head and neck

Clémence Guenne,1 Jérôme Fayette,2 Alain Cosmidis,1 Carine Fuchsmann,1 Sophie Tartas,3 Véronique Favrel,4 Philippe Céruse1 1Head and Neck Surgery Department, Lyon-I University, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; 2Medicine Department, Lyon-I University, Centre Léon Bérard, Lyon, France; 3Medical Oncology Department, Lyon-I University, Hospices Civils de Lyon, Lyon Sud Hospital, 4Radiotherapy Department, Lyon-I University, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France Background: No specific study has focused on patients with metastatic squamous cell carcinoma of the head and neck (SCCHN) at diagnosis. Due to high response rates of induction chemotherapy in chemo-naïve patients with localized disease, their prognosis should be better than patients with recurrent disease.Methods: From January 1, 2008 to July 1, 2012, we retrospectively collected all patients’ records with SCCHN diagnosed as metastatic. Patients, disease, treatment and its results were analyzed. Survival was calculated using the Kaplan–Meier method.Results: Of the 749 new patients treated for SCCHN in our institution, 16 (2.1%) were metastatic at diagnosis, of whom five had cytological results to prove it. Six patients died before treatment or had palliative care and ten received initial chemotherapy and then surgery and/or radiotherapy according to the primary response. Four patients treated with first-line chemotherapy with docetaxel-5FU-cisplatin (TPF) showed a complete response of metastatic lesions allowing locoregional treatment. The overall survival at 1 year and 3 years was 50% and 24%, respectively. The median survival was 7 months (1–72 months). Seven patients (43.7%) had a higher survival at 12 months, including five (31.5%) who are still alive without recurrence with a mean follow-up of 30 months. There was a significant difference in overall survival (P<0.01) between patients who had chemotherapy with TPF versus other therapeutic protocols. The median survival of patients with lung metastases only was 15 months (1–72 months), significantly higher than that of patients with liver and/or bone localizations, which was 2 months (1–9 months).Conclusion: Patients with metastatic SCCHN treated by TPF followed by multimodal treatment could achieve long survival. Keywords: squamous cell carcinoma, head and neck, metastases, TPF, cetuxima