Biotransformation of Phytosterols to Androstenedione in Two Phase Water-oil Systems

The microbial transformation of phytosterols to androstenedione (androst-4-ene-3,17-dione, AD) and androstadienedione (androsta-1,4-diene-3,17-dione, ADD) in two-phase water-oil systems by means of the strain Mycobacterium sp. MB3683 has been studied. The effect of some process conditions, like the agitation speed, the age and amount of inoculum, the temperature and some additional carbon sources have been investigated. The highest conversion rates were attained with 10–15 % of inolucum of age t = 16–20 h at T = 34–35 "C and n = 400 min–1. Media containing high concentrations of carbohydrates have a negative impact on the process, while the natural nitrogen sources influence beneficially the bioconversion. The use of silicon oil and polypropylene-glycol as solubilizing agents was found suitable for the above-mentioned biotransformation and permitted to increase considerably the amount of the substrate in the system. On the other hand, the biotransformation rate depended on the amount of the oils, because they inhibited the microbial cells growth

ON THE ACCURACY OF BOOTSTRAPPING SAMPLE QUANTILES OF STRONGLY MIXING SEQUENCES SHUXIA SUN

Abstract In this paper, we examine the rate of convergence of moving block bootstrap (MBB) approximations to the distributions of normalized sample quantiles based on strongly mixing observations. Under suitable smoothness and regularity conditions on the one-dimensional marginal distribution function, the rate of convergence of the MBB approximations to distributions of centered and scaled sample quantiles is of order O.n −1=4 log log n/

Thermodynamics of fluid elements in the context of saturated isothermal turbulence in molecular clouds

The presented paper is an attempt to investigate the dynamical states of an hydrodynamical isothermal turbulent self-gravitating system using some powerful tools of the classical thermodynamics. Our main assumption, inspired by the work of Keto et al. (2020), is that turbulent kinetic energy can be substituted for the macro-temperature of chaotic motion of fluid elements. As a proper sample for our system we use a model of turbulent self-gravitating isothermal molecular cloud which is at final stages of its life-cycle, when the dynamics is nearly in steady state. Starting from this point, we write down the internal energy for a physically small cloud's volume, and then using the first principle of thermodynamics obtain in explicit form the entropy, free energy, and Gibbs potential for this volume. Setting fiducial boundary conditions for the latter system (small volume) we explore its stability as a grand canonical ensemble. Searching for extrema of the Gibbs potential we obtain conditions for its minimum, which corresponds to a stable dynamical state of hydrodynamical system. This result demonstrates the ability of our novel approach.Comment: 7 pages, published version URL https://astro.bas.bg/AIJ/issues/n38/SDonkov.pd

Thermoacoustic tomography arising in brain imaging

We study the mathematical model of thermoacoustic and photoacoustic tomography when the sound speed has a jump across a smooth surface. This models the change of the sound speed in the skull when trying to image the human brain. We derive an explicit inversion formula in the form of a convergent Neumann series under the assumptions that all singularities from the support of the source reach the boundary

Time-dependent angularly averaged inverse transport

This paper concerns the reconstruction of the absorption and scattering parameters in a time-dependent linear transport equation from knowledge of angularly averaged measurements performed at the boundary of a domain of interest. We show that the absorption coefficient and the spatial component of the scattering coefficient are uniquely determined by such measurements. We obtain stability results on the reconstruction of the absorption and scattering parameters with respect to the measured albedo operator. The stability results are obtained by a precise decomposition of the measurements into components with different singular behavior in the time domain

Risk based monitoring does not reduce the cost of clinical trials

The article covers the topics of clinical trial budgeting when applying risk-based monitoring (RBM) model. The problem is that the new monitoring model requires the new model of clinical trail budgeting too, while today, the common practice is to apply an old, traditional fixed-price budgeting

Direct Energy Production From Hydrogen Sulfide in Black Sea Water - Electrochemical Study

A sulfide driven fuel cell is proposed to clean the Black Sea with the simultaneous A sulfide driven fuel cell is proposed to clean the Black Sea with the simultaneous production of energy. The process is hopeful even at low sulfide concentrations, i.e.10 to 25 mg/l being close to the ones in the Black Sea water. The main problem for the practical application of this type of fuel cell are the low current and power densities. The measurement of the generated electric current compared to the sulfide depletion show that the most probable anode reaction is oxidation of sulfide to sulfate. It is evident that parasite competitive reactions oxidation of sulfide occurs in the anode compartment of the fuel cell. The pH measurements shows that the transfer of hydroxylic anions from the cathodic compartment to the anodic one across the separating membrane is not fast enough to compensate its drop in the anode compartment