Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions : a randomized controlled trial

Titanium- prepared platelet rich fibrin (T-PRF) is an autologous hemo-component with a high concentration of platelets that also incorporates leukocytes, and growth factors into the dense fibrin matrix and can be used as a healing biomaterial. This study assesses the adjunctive use of T-PRF in intrabony defects (IBDs) with open flap debridement (OFD) in comparison with guided tissue regeneration (GTR) as a gold standard and OFD alone as a control. A total of 45 patients (15 per group) were randomized as either T-PRF (test group), GTR (test group), or OFD alone (control group) sites. Probing depth (PD), clinical attachment level (CAL), and IBD were recorded. The radiographic depth of IBD was also measured. Primary outcomes assessed were changes in PD, CAL, and radiographic IBD that were assessed at the beginning and nine months later.  The PRF and GTR group showed significant improvement in clinical parameters compared with the OFD alone (control group) at nine months. While there were no significant differences in PD and CAL between test groups (T-PRF and GTR groups), the significant difference was found in radiographic IBD depth. T-PRF may give similar successful results as GTR in the treatment of IBDs with endo-perio lesions

Correlation between the visibility of submandibular fossa and mandibular canal cortication on panoramic radiographs and submandibular fossa depth on CBCT

To identify a correlation between the submandibular fossa (SF) visibility and mandibular canal (MC) cortication on panoramic image and the depth of SF measured on CBCT and also correlation between the depth of SF and vertical and horizontal location of MC on CBCT. 500 CBCT scans and panoramic radiographs were evaluated. SF depth types were classified as type I ( 3mm) on CBCT. Visibility of SF and the cortication of MC on panoramic radiographs were compared with the depth of SF on CBCT. Distances between MC and mandibular inferior, buccal and lingual cortices were measured. No statistically significant correlation was found between radiolucent appearances of SF, cortication of MC, and depth of SF. The deepest part of the fossa was in the second molar area followed by third and first molars. Negative weak correlations were found between B-MC, L-MC distances and depth of SF. Visibility of SF and cortication of MC on panoramic radiographs did not correlate with the depth of SF. A marked radiolucent submandibular fossa on panoramic image does not undoubtedly indicate a deep fossa, which emphasizes the importance of 3-D imaging in implant planning

Association of socio-demographic, behavioral, and comorbidity-related factors with severity of periodontitis in Turkish patients

Objective: To assess the prevalence of comorbidities and periodontal diseases severity in dental patients and to determine the socio-demographic, behavioral, and comorbidity-related predictors of periodontal diseases severity. Material and methods: This retrospective study sample consisted of 2458 patients who referred to faculty dentistry clinic. Socio-demographic, behavioral, and comorbidity characteristics of study participants were collected using hospital database and self-reported questionnaire. Descriptive, bivariate, and multivariate analyses were used to analyze study data. Results: Of these patients, 55.2% had mild-to-moderate periodontitis and 44.8% had severe periodontitis. The severity of periodontal disease was significantly associated with the presence of comorbidity, the number of comorbidities, age, gender, income level, smoking, and alcohol consumption. Patients with severe periodontitis were more likely being a current smoker, to report drinking alcohol sometimes or every day, to be a male, to have a pulmonary disease, to have an endocrinological and metabolic disorder, to have a cardiovascular disorder and to have a neurological disorder than those with mild/moderate periodontitis. Having a hematological disorder, having a muscle, skeletal and connective tissue disorder, to be a current smoker and lower age were found to be predictors of moderate periodontitis whereas being a female and lower number of comorbidities were predictors of mild periodontitis. Conclusions: The severity of periodontitis was associated with socio-demographic, behavioral, and comorbidity characteristics of periodontal patients