467 research outputs found

    Organizational Learning, Quality Strategy and Perceived Firm Performance of Textile Firms

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    This study employs organizational learning theory and quality strategy theory to formulate a new organizational learning-quality strategy- that can be used to enhance firm performance of the firms of textile sector listed at Pakistan Stock exchange. This research explores the moderating role of quality strategy in the relation between organizational learning and perceived firm performance. This article also explores the effect of organizational learning on quality strategy and perceived firm performance, as well as the impact of quality strategy on perceived firm performance. The model was tested using the experience of 300 Pakistani textile firms operating in a variety of host markets. To test the moderating role, process developed by Hayes was used. The empirical results indicate that perceived firm performance is significantly affected by organizational learning (explorative and exploitative learning) and quality strategy. Furthermore, the results confirm that the explorative, exploitative learning and quality strategy have a positive relationship with perceived firm performance and quality strategy moderates the relationship between organizational learning and perceived firm performance. The outcomes of this article provide a new direction for future research regarding organizational learning, quality strategy and perceived firm performance

    Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis.

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    Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA). GPA commonly involves the lungs and the kidneys. Among the pulmonary manifestations, diffuse alveolar hemorrhage (DHA) is a rare presentation of GPA that can present with hemoptysis leading to acute onset of anemia and hemodynamic instability. An active diagnostic workup including serologic titer of C-ANCA, imaging, intensive care, and aggressive immunosuppression is the key to DAH management. We report a case of DAH secondary to GPA that presented with hemoptysis leading to severe anemia, initially resuscitated symptomatically and started on plasmapheresis with pulse steroids and cyclophosphamide. Timely diagnosis and management led to a remarkable recovery of the pulmonary symptoms and imaging findings of DAH

    Spontaneous Lung Herniation Leading to Extensive Subcutaneous Emphysema, Pneumothorax, Pneumomediastinum, and Pneumopericardium.

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    Spontaneous lung herniation is a rare phenomenon in which the lung parenchyma along with the pleural membranes protrudes outside their usual boundaries and can lead to a wide variety of complications. We are reporting a case of a middle-aged male who presented with chronic obstructive pulmonary disease (COPD) exacerbation with severe bouts of cough. Initial computed tomography (CT) chest was unrevealing, but two days later, he developed spontaneous lung herniation, which was initially managed conservatively, but later it progressed to pneumothorax, pneumomediastinum, with striking CT scan images showing extensive subcutaneous emphysema. Blowhole incisions were done on the anterior chest wall which led to ultimate recovery

    Factors Affecting Catheter Contact in the Human Left Atrium, its Impact on the Electrogram and Radiofrequency Ablation.

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    PhDThe interaction between the mapping/ablation catheter and left atrial (LA) myocardium potentially affects the LA electrical and mechanical properties and impacts on ablation efficacy. Using catheters able to provide real-time contact force (CF) measurement, it has become possible to explore these relationships in vivo. In 60 persistent atrial fibrillation (AF) patients, ablation CF was higher in the right than left wide area circumferential (WACA) lines and where steerable transseptal sheaths were used. Differences were also apparent in the burden of WACA segment reconnection but did not just reflect differences in ablation CFs, suggesting factors other than CF contribute to ablation efficacy. Relationships between ablation force time integral (FTI), impedance drop and electrogram attenuation were assessed in 15 persistent AF patients. FTI significantly correlated with electrogram attenuation and impedance drop from ablation. The relationship was stronger for the former but in both cases plateaued at 500g.s, suggesting no ablation efficacy gains beyond this. Factors further affecting CF and ablation efficacy, the latter judged by impedance drop, were assessed in 30 patients. The variability of the CF waveform and catheter locational stability were both affected by factors including atrial rhythm and catheter delivery mode. Greater CF variability, catheter drift and perpendicular catheter contact were associated with reduced ablation efficacy. The relationship between CF and the electrogram was assessed in 30 patients. The size of the electrogram complexes was affected by CF increases but only where initial CF was <10g. This was also the case for electrogram fractionation measurements. Increasing CF was associated with an increasing incidence of atrial ~ 3 ~ ectopics during sinus rhythm. Spectral parameters (dominant frequency and organisation index) were unaffected by CF. Various factors affect the contact between the catheter and LA myocardium. In turn, catheter contact significantly affects the electrogram during LA mapping and the efficacy of clinical radiofrequency ablation

    Isolation and Evaluation of Antibacterial Potential Test of Plant Carthamus oxycantha

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    The present investigation was initiated to find a suitable alternative to synthetic antibiotics for the management of diseases caused by bacteria. Carthamus oxycantha.L locally known as wild safflower member of family Asteraceae that grows wildly. The study was conducted using as Agar well diffusion to trace the antibacterial potential for to evaluate the efficiency of ethanolic extract of Carthamus oxycantha with concentration of 05, 10, 15, and 20 mg/ml against gram-positive Staphylococcus aureus and gram-negative Escherichia Coli species and them compared with that of Clindamycin, Ampicillin and Kanamycin (10 mg). Zone of inhibition for the extracts were 10.667 to 20.00 mm as compared to standard drug Clindamycin, Ampicillin and kanamycin (15.00-20.00 mm). Antibacterial assays indicates that Carthamus oxycantha has potential natural antimicrobial agents against E-coli and S. aureus. The findings of the present study suggested that ethanolic extract of C. oxycantha has strong potential to serve as possible antibacterial
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