4 research outputs found
Pediatric Sepsis Guidelines: Summary for resource-limited countries
Justification: Pediatric sepsis is a commonly encountered global issue.
Existing guidelines for sepsis seem to be applicable to the developed
countries, and only few articles are published regarding application of
these guidelines in the developing countries, especially in
resource-limited countries such as India and Africa. Process: An
expert representative panel drawn from all over India, under aegis of
Intensive Care Chapter of Indian Academy of Pediatrics (IAP) met to
discuss and draw guidelines for clinical practice and feasibility of
delivery of care in the early hours in pediatric patient with sepsis,
keeping in view unique patient population and limited availability of
equipment and resources. Discussion included issues such as sepsis
definitions, rapid cardiopulmonary assessment, feasibility of early
aggressive fluid therapy, inotropic support, corticosteriod therapy,
early endotracheal intubation and use of positive end expiratory
pressure/mechanical ventilation, initial empirical antibiotic therapy,
glycemic control, and role of immunoglobulin, blood, and blood
products. Objective: To achieve a reasonable evidence-based consensus
on the basis of published literature and expert opinion to formulating
clinical practice guidelines applicable to resource-limited countries
such as India. Recommendations: Pediatric sepsis guidelines are
presented in text and flow chart format keeping resource limitations in
mind for countries such as India and Africa. Levels of evidence are
indicated wherever applicable. It is anticipated that once the
guidelines are used and outcomes data evaluated, further modifications
will be necessary. It is planned to periodically review and revise
these guidelines every 3-5 years as new body of evidence accumulates