Finsler geometry modeling of phase separation in multi-component membranes

Finsler geometric surface model is studied as a coarse-grained model for membranes of three-component such as DOPC, DPPC and Cholesterol. To understand the phase separation of liquid ordered (DPPC rich) $L_o$ and the liquid disordered (DOPC rich) $L_d$, we introduce a variable $\sigma (\in \{1,-1\})$ in the triangulated surface model. We numerically find that there appear two circulars and stripe domains on the surface and that these two morphologies are separated by a phase transition. The morphological change from the one to the other with respect to the variation of the area fraction of $L_o$ is consistent with existing experimental results. This gives us a clear understanding of the origin of the line tension energy, which has been used to understand those morphological changes in the three-component membranes. In addition to these two circulars and stripe domains, raft-like domain and budding domain are also observed, and the corresponding several phase diagrams are obtained. Technical details of the Finsler geometry modeling are also shown.Comment: 18 pages, 11 figure

Impact of Metrical Prosody on Performances

This thesis is about testing Frederick Turner and Ernst Pöppel\u27s claim that suggestmetrical poem tends to measure three seconds in terms of psychological limitwhen it is performed aloud. The objective of the study is to present metricalpoems as the new data to test their claim by using corpus analysis. Hereby, theresearcher uses publicly available 28 read-aloud poems from poetryoutloud.orgby using Praat to find the duration of each metrical line. The findings indicate thatthere are 18 English metrical poems with 314 lines in total, supported by metricaltree analysis, meanwhile there are 10 poems which are free verse and found that1) most lines have iamb feet, 2) 10 of the metrical pattern of the poems are iambicpentameter, whereas others are in diverse meter, 3) there is no psychological limiton the duration of metrical lines in performance as the researcher only founds62.73% that fit to the 3 seconds of temporal window based on the analysis in thecorpus of 314 metrical lines. This study has shown what Frederick Turner andErnst Pöppel claim is not methodologically proven

Analysis of the Pathogenesis of Experimental Autoimmune Optic Neuritis

Optic neuritis associated with multiple sclerosis has a strong association with organ-specific autoimmune disease. The goal of our research is to establish an optimal organ-specific animal model to elucidate the pathogenetic mechanisms of the disease and to develop therapeutic strategies using the model. This paper is divided into five sections: (1) clinical picture of optic neuritis associated with multiple sclerosis, (2) elucidation of pathogenesis using animal models with inflammation in optic nerve and spinal cord, (3) clinical relevance of concurrent encephalomyelitis in optic neuritis model, (4) retinal damage in a concurrent multiple sclerosis and optic neuritis model, and (5) development of novel therapies using mouse optic neuritis model. Advanced therapies using biologicals have succeeded to control intractable optic neuritis in animal models. This may ultimately lead to prevention of vision loss within a short period from acute onset of optic neuritis in human. By conducting research flexibly, ready to switch from the bench to the bedside and from the bedside to the bench as the opportunity arises, this strategy may help to guide the research of optic neuritis in the right direction

Quadrupole moments in chiral material DyFe3(BO3)4 observed by resonant x-ray diffraction

By means of circularly polarized x-ray beam at Dy L3 and Fe K absorption edges, the chiral structure of the electric quadrupole was investigated for a single crystal of DyFe3(BO3)4 in which both Dy and Fe ions are arranged in spiral manners. The integrated intensity of the resonant x- ray diffraction of space-group forbidden reflections 004 and 005 is interpreted within the electric dipole transitions from Dy 2p3 to 5d and Fe 1s to 4p, respectively. We have confirmed that the 2 handedness of the crystal observed at Dy L3 and Fe K edges is consistent with that observed at Dy M5 edge in the previous study. By analyzing the azimuth scans of the diffracted intensity, the electronic quadrupole moments of Dy 5d and Fe 4p are derived. The temperature profiles of the integrated intensity of 004 at the Dy L3 and the Fe K edges are similar to those of Dy-O and Fe-O bond lengths, while that at the Dy M5 edge does not. The results indicate that the helix chiral orientations of quadrupole moments due to Dy 5d and Fe 4p electrons are more strongly affected by the crystal fields than Dy 4f

STUDY ON APPLICATION OF DRAG-REDUCING TRIMETHYLOLETHANE SLURRY IN DISTRICR COOLING SYSTEM

Trimethylolethane (TME) trihydrate slurry is a proper phase-change material for latent heat transportation in cooling systems since it has excellence heat transfer performance and high thermal capacity. Additives, oleyl bishydroxyethyl methyl ammonium chloride (as surfactant) and sodium salicylate (as counter-ion), were used as drag-reducer substance. These additives not only induce drag reduction in TME slurry, but also control particle growth and agglomeration. In this study, energy saving estimation of drag-reducing TME slurry application in district cooling system is invesitgated. It is found that drag-reducing TME slurry gives remarkable pumping power suppresion in the district cooling system. To maintain high performance of heat exchangers, heat transfer enhancement technique may be needed in those exchangers

The ASTRO-F Mission : Large Area Infrared Survey

ASTRO-F is the first Japanese satellite mission dedicated for large area surveys in the infrared. The 69cm aperture telescope and scientific instruments are cooled to 6K by liquid Helium and mechanical coolers. During the expected mission life of more than 500 days, ASTRO-F will make the most advanced all-sky survey in the mid- to far-infrared since the Infrared astronomical Satellite (IRAS). The survey will be made in 6 wavebands and will include the first all sky survey at >100-160(mu)m. Deep imaging and spectroscopic surveys with pointed observations will also be carried out in 13 wavelength bands from 2-160(mu)m. ASTRO-F should detect more than a half million galaxies tracing the large-scale structure of the Universe out to redshifts of unity, detecting rare, exotic extraordinarily luminous objects at high redshift, numerous brown dwarfs, Vega-like stars, protostars, and will reveal the large-scale structure of nearby galactic star forming regions. ASTRO-F is a perfect complement to Spitzer Space Telescope in respect of its wide sky and wavelength coverage. Approximately 30 percent of pointed observations will be allocated to an open-time opportunity. Updated pre-flight ensitivities as well as the observation plan including the large-area surveys are described.Comment: accepted for publication in Advances in Space Research, 15 pages, 7 Postscript figures, uses elsart.cl