1,082 research outputs found
Canonical Quantization Inside the Schwarzschild Black Hole
We propose a scheme for quantizing a scalar field over the Schwarzschild
manifold including the interior of the horizon. On the exterior, the timelike
Killing vector and on the horizon the isometry corresponding to restricted
Lorentz boosts can be used to enforce the spectral condition. For the interior
we appeal to the need for CPT invariance to construct an explicitly positive
definite operator which allows identification of positive and negative
frequencies. This operator is the translation operator corresponding to the
inexorable propagation to smaller radii as expected from the classical metric.
We also propose an expression for the propagator in the interior and express it
as a mode sum.Comment: 8 pages, LaTex. Title altered. One reference added. A few typos esp.
eq.(7),(38) corrected. To appear in Class.Q.Gra
The fourth monitoring report of the Early vs. Late Infantile Strabismus Surgery Study
The Early vs. Late Infantile Strabismus Surgery Study Group is a group of strabismologists and orthoptists from 58 clinics in 11 European countries. They investigate whether early or late surgery is preferable in infantile strabismus, in a non-randomized, prospective, multi-center trial. Infants between 6 and 18 months of age receive a standardized entry examination and are then operated either before their second anniversary in clinics A, or between their 32nd and 60th month of age in clinics B. The children are evaluated at age six. After completion of the study, the two groups can then be compared regarding degree of binocular vision, angle of strabismus and visual acuity of the worse eye relative to the better. The current status of the study is reported here. Up to December 13, 1996, 58 clinics have entered a total of 532 patients. Currently, 232 children have been entered in the early surgery group and 300 in the late surgery group. Completeness of data and forms are excellent. Thirty-eight patients have definitively dropped out. There is no evidence for inhomogeneities between the two therapy groups concerning the distribution of the four most important prognostic factors: spherical equivalents, horizontal angle of squint, degree of amblyopia and limitation of abduction
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension
Background
A post-hoc analysis was performed on the data from a 54 weeks phase III study (ClinicalTrials.gov identifier: NCT00923091) to measure changes in the health-related quality of life (HRQoL) of 2,690 patients aged ≥18 with moderate-to-severe hypertension who received one of six doses of olmesartan/amlodipine/hydrochlorothiazide (OLM/AML/HCTZ), using the MINICHAL and EQ-5D instruments.
Methods
Descriptive statistics were used to assess blood pressure and HRQoL scores over the study period. Analysis of covariance (ANCOVA) was used to identify those factors that could possibly have influenced HRQoL. Linear regression was used to assess the relationship between changes in blood pressure and HRQoL scores.
Results
Patients’ baseline MINICHAL mood and somatic domains scores were 5.5 and 2.6. Over the study period HRQoL improved as both MINICHAL scores decreased by 31-33%. Patients’ baseline EQ-5D index and VAS scores were 0.9 and 73.4 respectively, increasing by 6% and 12% over the study period. Patients’ QALY gain over the 54 weeks study period was estimated to be 0.029 QALYs. The ANCOVA showed that changes in patients’ HRQoL was likely to have been influenced by patients’ achievement of blood pressure control, the amount of concomitant medication and patients’ last used dosage strength of antihypertensive. Linear regression showed that blood pressure improvement may have been associated with improved HRQoL.
Conclusions
This study showed that OLM/AML/HCTZ reduced blood pressure and significantly increased blood pressure control whilst improving patients’ HRQoL. Achieving blood pressure control, amount of concomitant medication and dosage strength of antihypertensive impacted on patients’ HRQoL
The Quest for Understanding in Relativistic Quantum Physics
We discuss the status and some perspectives of relativistic quantum physics.Comment: Invited contribution to the Special Issue 2000 of the Journal of
Mathematical Physics, 38 pages, typos corrected and references added, as to
appear in JM
Algebraic Quantum Theory on Manifolds: A Haag-Kastler Setting for Quantum Geometry
Motivated by the invariance of current representations of quantum gravity
under diffeomorphisms much more general than isometries, the Haag-Kastler
setting is extended to manifolds without metric background structure. First,
the causal structure on a differentiable manifold M of arbitrary dimension
(d+1>2) can be defined in purely topological terms, via cones (C-causality).
Then, the general structure of a net of C*-algebras on a manifold M and its
causal properties required for an algebraic quantum field theory can be
described as an extension of the Haag-Kastler axiomatic framework.
An important application is given with quantum geometry on a spatial slice
within the causally exterior region of a topological horizon H, resulting in a
net of Weyl algebras for states with an infinite number of intersection points
of edges and transversal (d-1)-faces within any neighbourhood of the spatial
boundary S^2.Comment: 15 pages, Latex; v2: several corrections, in particular in def. 1 and
in sec.
Dialogue Concerning Two Views on Quantum Coherence: Factist and Fictionist
A controversy that has arisen many times over in disparate contexts is
whether quantum coherences between eigenstates of certain quantities are fact
or fiction. We present a pedagogical introduction to the debate in the form of
a hypothetical dialogue between proponents from each of the two camps: a
factist and a fictionist. A resolution of the debate can be achieved, we argue,
by recognizing that quantum states do not only contain information about the
intrinsic properties of a system but about its extrinsic properties as well,
that is, about its relation to other systems external to it. Specifically, the
coherent quantum state of the factist is the appropriate description of the
relation of the system to one reference frame, while the incoherent quantum
state of the fictionist is the appropriate description of the relation of the
system to another, uncorrelated, reference frame. The two views, we conclude,
are alternative but equally valid paradigms of description.Comment: 14 pages, Contribution to the Int. J. of Quant. Info. issue dedicated
to the memory of Asher Peres; v2 updated summary and critique of prior
literatur
Verification of Item Usage Rules in Product Configuration
In the development of complex products product configuration systems are often used to support the development process. Item Usage Rules (IURs) are conditions for including specific items in products bills of materials based on a high-level product description. Large number of items and significant complexity of IURs make it difficult to maintain and analyze IURs manually. In this paper we present an automated approach for verifying IURs, which guarantees the presence of exactly one item from a predefined set in each product, as well as that an IUR can be reformulated without changing the set of products for which the item was included
Numerical simulations of homogeneous freezing processes in the aerosol chamber AIDA
The homogeneous freezing of supercooled H<sub>2</sub>SO<sub>4</sub>/H<sub>2</sub>O aerosols in an aerosol chamber is investigated with a microphysical box model using the activity parameterization of the nucleation rate by Koop et al. (2000). The simulations are constrained by measurements of pressure, temperature, total water mixing ratio, and the initial aerosol size distribution, described in a companion paper Möhler et al. (2003). Model results are compared to measurements conducted in the temperature range between 194 and 235 K, with cooling rates in the range between 0.5 and 2.6 K min<sup>-1</sup>, and at air pressures between 170 and 1000 hPa. The simulations focus on the time history of relative humidity with respect to ice, aerosol size distribution, partitioning of water between gas and particle phase, onset times of freezing, freezing threshold relative humidities, aerosol chemical composition at the onset of freezing, and the number of nucleated ice crystals. The latter four parameters can be inferred from the experiments, the former three aid in interpreting the measurements. Sensitivity studies are carried out to address the relative importance of uncertainties of basic quantities such as temperature, total H<sub>2</sub>O mixing ratio, aerosol size spectrum, and deposition coefficient of H<sub>2</sub>O molecules on ice. The ability of the numerical simulations to provide detailed explanations of the observations greatly increases confidence in attempts to model this process under real atmospheric conditions, for instance with regard to the formation of cirrus clouds or polar stratospheric ice clouds, provided that accurate temperature and humidity measurements are available
Freezing thresholds and cirrus cloud formation mechanisms inferred from in situ measurements of relative humidity
International audienceFactors controlling the distribution of relative humidity above ice saturation in the upper troposphere and lower stratosphere in the presence of cirrus clouds are examined with the help of microphysical trajectory simulations using a box model. Our findings are related to results from recent field campaigns and global model studies. We suggest that the relative humidities at which ice crystals form in the atmosphere can be inferred from in situ measurements of water vapor and temperature close to, but outside of, cirrus clouds. The comparison with similar measurements performed inside cirrus clouds provides a clue to freezing mechanisms active in cirrus. The comparison with field data reveals distinct interhemispheric differences in cirrus cloud freezing thresholds. Combining the present findings with recent results addressing the frequency distributions of updraft speeds and cirrus ice crystal number densities (Kärcher and Ström, 2993} provides evidence for the existence of complex heterogeneous freezing mechanisms in cirrus, at least in the polluted northern hemisphere, and further emphasizes the key role of gravity wave-induced dynamical variability in vertical air motion at the mesoscale. The key features of distributions of upper tropospheric relative humidity simulated by a global climate model are shown to be in general agreement with both, microphysical simulations and field observations, delineating a feasible method to include and validate ice supersaturation in other large-scale models of the atmosphere, in particular chemistry-transport and weather forecast models
Zeno Dynamics of von Neumann Algebras
The dynamical quantum Zeno effect is studied in the context of von Neumann
algebras. We identify a localized subalgebra on which the Zeno dynamics acts by
automorphisms. The Zeno dynamics coincides with the modular dynamics of that
subalgebra, if an additional assumption is satisfied. This relates the modular
operator of that subalgebra to the modular operator of the original algebra by
a variant of the Kato-Lie-Trotter product formula.Comment: Revised version; further typos corrected; 9 pages, AMSLaTe
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