2,425 research outputs found
How architects incorporate ESD criteria into the design process
This paper will seek to answer; "How do architects in Victoria incorporate Ecologically Sustainable Development (ESD) criteria into the design process?" For the purpose of this paper, "Ecologically Sustainable Development" is defined in line with the judging criteria used by the Royal Australian Institute of Architects for the \u27Sustainable Architecture Award\u27. The RAIA states that (Maddison, 2003 p.7), "the goal of sustainable architecture is to achieve development that improves the total quality of life, in a way that maintains the processes on which life depends. The project assessment covers ecologically sustainable development and energy efficient design:\u27 By researching exemplary building projects that have been awarded a Victorian Sustainable Architecture Award, this paper will enlighten a design methodology for the pursuit of excellence in ecologically sustainable development. Key elements in the design process will be determined by comparing and analysing the processes of different architectural practices. This will be achieved through the study of published literature on the award winning designs, qualitative analysis of interviews with the architects who designed the selected projects and quantitative analysis of questionnaires completed by the architects.<br /
The SkyMapper Transient Survey
The SkyMapper 1.3 m telescope at Siding Spring Observatory has now begun
regular operations. Alongside the Southern Sky Survey, a comprehensive digital
survey of the entire southern sky, SkyMapper will carry out a search for
supernovae and other transients. The search strategy, covering a total
footprint area of ~2000 deg2 with a cadence of days, is optimised for
discovery and follow-up of low-redshift type Ia supernovae to constrain cosmic
expansion and peculiar velocities. We describe the search operations and
infrastructure, including a parallelised software pipeline to discover variable
objects in difference imaging; simulations of the performance of the survey
over its lifetime; public access to discovered transients; and some first
results from the Science Verification data.Comment: 13 pages, 11 figures; submitted to PAS
Using self-monitoring to detect and manage raised blood pressure and pre-eclampsia during pregnancy: the BUMP research programme and its impact
Raised blood pressure affects around ten percent of pregnancies worldwide, causing maternal and perinatal morbidity and mortality. Self-monitoring of blood pressure during higher-risk or hypertensive pregnancy has been shown to be feasible, acceptable, safe, and no more expensive than usual care alone. Additionally, self-testing for proteinuria has been shown to be just as accurate as healthcare professional testing, creating the potential for monitoring of multiple indicators through pregnancy. The work suggests however, that an organisational shift is needed to properly use and see benefits from self-monitored readings. This paper describes the findings from a large programme of work examining the use of self-monitoring in pregnancy, summarising the findings in the context of the wider literature and current clinical context
The Adirondack Chronology
The Adirondack Chronology is intended to be a useful resource for researchers and others interested in the Adirondacks and Adirondack history.https://digitalworks.union.edu/arlpublications/1000/thumbnail.jp
Subject preferences of fifth-grade children.
Thesis (Ed.M.)--Boston University
N.B.:Pages 155 and 309 are missing from original thesis
The Bullet cluster at its best: weighing stars, gas and dark matter
We present a new strong lensing mass reconstruction of the Bullet cluster (1E
0657-56) at z=0.296, based on WFC3 and ACS HST imaging and VLT/FORS2
spectroscopy. The strong lensing constraints underwent substantial revision
compared to previously published analysis, there are now 14 (six new and eight
previously known) multiply-imaged systems, of which three have
spectroscopically confirmed redshifts (including one newly measured from this
work). The reconstructed mass distribution explicitly included the combination
of three mass components: i) the intra-cluster gas mass derived from X-ray
observation, ii) the cluster galaxies modeled by their fundamental plane
scaling relations and iii) dark matter. The model that includes the
intra-cluster gas is the one with the best Bayesian evidence. This model has a
total RMS value of 0.158" between the predicted and measured image positions
for the 14 multiple images considered. The proximity of the total RMS to
resolution of HST/WFC3 and ACS (0.07-0.15" FWHM) demonstrates the excellent
precision of our mass model. The derived mass model confirms the spatial offset
between the X-ray gas and dark matter peaks. The fraction of the galaxy halos
mass to total mass is found to be f_s=11+/-5% for a total mass of 2.5+/-0.1 x
10^14 solar mass within a 250 kpc radial aperture.Comment: Accepted by A&A 15 pages, 12 figure
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Mammographic breast density: comparison of methods for quantitative evaluation.
PURPOSE: To evaluate the results from two software tools for measurement of mammographic breast density and compare them with observer-based scores in a large cohort of women. MATERIALS AND METHODS: Following written informed consent, a data set of 36 281 mammograms from 8867 women were collected from six United Kingdom centers in an ethically approved trial. Breast density was assessed by one of 26 readers on a visual analog scale and with two automated density tools. Mean differences were calculated as the mean of all the individual percentage differences between each measurement for each case (woman). Agreement in total breast volume, fibroglandular volume, and percentage density was assessed with the Bland-Altman method. Association with observer's scores was calculated by using the Pearson correlation coefficient (r). RESULTS: Correlation between the Quantra and Volpara outputs for total breast volume was r = 0.97 (P < .001), with a mean difference of 43.5 cm(3) for all cases representing 5.0% of the mean total breast volume. Correlation of the two measures was lower for fibroglandular volume (r = 0.86, P < .001). The mean difference was 30.3 cm(3) for all cases representing 21.2% of the mean fibroglandular tissue volume result. Quantra gave the larger value and the difference tended to increase with volume. For the two measures of percentage volume density, the mean difference was 1.61 percentage points (r = 0.78, P < .001). Comparison of observer's scores with the area-based density given by Quantra yielded a low correlation (r = 0.55, P < .001). Correlations of observer's scores with the volumetric density results gave r values of 0.60 (P < .001) and 0.63 (P < .001) for Quantra and Volpara, respectively. CONCLUSION: Automated techniques for measuring breast density show good correlation, but these are poorly correlated with observer's scores. However automated techniques do give different results that should be considered when informing patient personalized imaging. (©) RSNA, 2015 Clinical trial registration no. ISRCTN 73467396.Supported by the National Institute for Health Research’s Health Technology Assessment Programme.This is the final version of the article. It first appeared at http://pubs.rsna.org/doi/full/10.1148/radiol.1414150
Analysis of mutations in West Australian populations of Blumeria graminis f. sp. hordei CYP51 conferring resistance to DMI fungicides
BACKGROUND
Powdery mildew caused by Blumeria graminis f. sp. hordei (Bgh) is a constant threat to barley production but is generally well controlled through combinations of host genetics and fungicides. An epidemic of barley powdery mildew was observed from 2007 to 2013 in the West Australian grain belt. RESULTS
We collected isolates across Australia, examined their sensitivity to demethylation inhibitor (DMI) fungicides and sequenced the Cyp51B target gene. Five amino acid substitutions were found, of which four were novel. The most resistant haplotypes increased in prevalence from 0% in 2009 to 16% in 2010 and 90% in 2011. Yeast strains expressing the Bgh Cyp51 haplotypes replicated the altered sensitivity to various DMIs and these results were complemented by in silico protein docking studies. CONCLUSIONS
The planting of very susceptible cultivars and the use of a single fungicide mode of action was followed by the emergence of a major epidemic of barley powdery mildew. Widespread use of DMI fungicides led to the selection of Bgh isolates carrying both the Y137F and S524T mutations, which, as in Zymoseptoria tritici, account for resistance factors varying from 3.4 for propiconazole to 18 for tebuconazole, the major azoles used at that time in WA. © 2019 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry
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