Amino acids and biogenic amines evolution during the estufagem of fortified wines

The current study was focused on the impact of accelerated ageing (heating step) on the amino acid and biogenic amine profiles of fortified wines. In this sense, three Madeira wines from two commonly used grape varieties (one red and the other white) were analysed during the heating, at standard (45∘ C, 3 months) and overheating (70∘ C, 1 month) conditions, following a precolumn derivatization procedure using iodoacetic acid, o-phthaldialdehyde, and 2-mercaptoethanol, carried out in the injection loop prior to RP-HPLC-FLD detection. Eighteen amino acids were identified, with arginine being the most abundant. An important decrease of the amino acid levels was detected during the standard heating (up to 30%), enhanced up to 61% by the temperature increase. Cysteine, histidine, and asparagine revealed the greatest decreases at 45∘ C. Conversely, some amino acids, such as asparagine, slightly increased. Four biogenic amines were identified but always in trace amounts. Finally, it was observed that the accelerated ageing did not favour the biogenic amine development. The results also indicate that the heating process promotes the amino acid transformation into new ageing products.info:eu-repo/semantics/publishedVersio

Content in metallic ions of wines from the Madeira and Azores archipelagos

This study determines for the first time Na, K, Ca, Mg, Fe, Cu, Zn, Mn, Sr, Li and Rb contents in wines from the archipelagos of Madeira and Azores (Portugal). The greater part of the mean content for the different parameters fell within the ranges described in the literature, except for sodium whose higher content may be due to the effect of marine spray. ANOVA was used to establish the metals with significant differences in mean content between the wines from both archipelagos, between table and liquor wines of Madeira, and between wines of Pico and Terceira Islands from the Azores archipelago. Principal component analysis shows differences in the wines according to the wine-making process and/or the equipment employed. Stepwise linear discriminant analysis achieves a good classification and validation of wines according to the archipelago of origin, and the island in the case of Azores wines

Atypical modulations of N170 component during emotional processing and their links to social behaviors in ex-combatants

ABSTRACT: Emotional processing (EP) is crucial for the elaboration and implementation of adaptive social strategies. EP is also necessary for the expression of social cognition and behavior (SCB) patterns. It is well-known that war contexts induce socio-emotional atypical functioning, in particular for those who participate in combats. Thus, ex-combatants represent an ideal non-clinical population to explore EP modulation and to evaluate its relation with SCB. The aim of this study was to explore EP and its relation with SCB dimensions such as empathy, theory of mind and social skills in a sample of 50 subjects, of which 30 were ex-combatants from illegally armed groups in Colombia, and 20 controls without combat experience. We adapted an Emotional Recognition Task for faces and words and synchronized it with electroencephalographic recording. Ex-combatants presented with higher assertion skills and showed more pronounced brain responses to faces than Controls. They did not show the bias toward anger observed in control participants whereby the latter group was more likely to misclassify neutral faces as angry. However, ex-combatants showed an atypical word valence processing. That is, words with different emotions yielded no differences in N170 modulations. SCB variables were successfully predicted by neurocognitive variables. Our results suggest that in ex-combatants the links between EP and SCB functions are reorganized. This may reflect neurocognitive modulations associated to chronic exposure to war experiences

Atypical modulations of N170 component during emotional processing and their links to social behaviors in ex-combatants

Emotional processing (EP) is crucial for the elaboration and implementation of adaptive social strategies. EP is also necessary for the expression of social cognition and behavior (SCB) patterns. It is well-known that war contexts induce socio-emotional atypical functioning, in particular for those who participate in combats. Thus, ex-combatants represent an ideal non-clinical population to explore EP modulation and to evaluate its relation with SCB. The aim of this study was to explore EP and its relation with SCB dimensions such as empathy, theory of mind and social skills in a sample of 50 subjects, of which 30 were ex-combatants from illegally armed groups in Colombia, and 20 controls without combat experience. We adapted an Emotional Recognition Task for faces and words and synchronized it with electroencephalographic recording. Ex-combatants presented with higher assertion skills and showed more pronounced brain responses to faces than Controls. They did not show the bias toward anger observed in control participants whereby the latter group was more likely to misclassify neutral faces as angry. However, ex-combatants showed an atypical word valence processing. That is, words with different emotions yielded no differences in N170 modulations. SCB variables were successfully predicted by neurocognitive variables. Our results suggest that in ex-combatants the links between EP and SCB functions are reorganized. This may reflect neurocognitive modulations associated to chronic exposure to war experiences. © 2017 Trujillo, Valencia, Trujillo, Ugarriza, Rodríguez, Rendón, Pineda, López, Ibañez and Parra

An actionable knowledge discovery system in regular sports services

This work presents an actionable knowledge discovery system for real user needs with three steps. In the first step, it extracts and transforms existing data in the databases of the ERP and CRM systems of the sports facilities and loads them into a Data Warehouse. In a second phase, predictive models are applied to identify profiles more susceptible to abandonment. Finally, in the third phase, based on the previous models, experimental planning is carried out, with test and control groups, in order to find concrete actions for customer retention.info:eu-repo/semantics/publishedVersio

La educación en el conflicto armado desde una perspectiva analógica del semillero Vórtice y el libro Desterrados de Alfredo Molano

Este ensayo est´a planificado con base a los objetivos del Semillero Vórtice y al análisis del libro Desterrados, en el cual enmarca las dinámicas y manifestaciones sociales en el conflicto armado interno que han irrumpido el espacio social; de esta manera, se consideran múltiples factores que inciden en la formulación de una educación para la paz en los estudiantes y maestros, entretanto surgen distinciones entre educación y pedagogía, de ahí, planteando una adecuada pedagogía para la paz desde la teoría y la practica en cada uno de los referentes analizados. Al mismo tiempo se observa que cada acción pedagógica tiene un fin política, en este caso el semillero Vórtice fomenta desde la acción pedagógica investigativa la convivencia escolar en los territorios del posconflicto en la educación rural. De igual forma, se logra implantar la importancia de mostrar y analizar los objetivos del ente investigador y el libroDesterrados para darle un acercamiento a las prácticas de la resolución del conflicto interno en las instituciones, con el propósito de instaurar la necesidad relevante en la creación de una pedagogía para la paz, Recreando una importancia inmediata en los procesos de justicia, reparación y construcción de memoria para la necesidad de una paz estable y duradera

Elastic response of cross-laminated engineered bamboo panels subjected to in-plane loading

© ICE Publishing: All rights reserved. Novel cross-laminated bamboo panels comprising three and five layers (G-XLam3 and G-XLam5) were tested in compression along the main (0°) and the transverse (90°) directions. Linear variable differential transformer (LVDT) and non-contact three-dimensional digital image correlation (DIC) measuring techniques were used separately to measure deformation in the elastic region, and the elastic moduli, Ep C,0 and Ep C,90, were derived. Mean elastic modulus values obtained using LVDTs exhibited a good match with analytically predicted values. In contrast, the elastic values obtained by the DIC method were considerably higher and presented a considerable scatter of results. For instance, the Ep C,0 for G-XLam3 and G-XLam5 panels were 17·22 and 15·67 GPa, and 14·86 and 12·48 GPa, using the DIC and LVDT methods, respectively. In general, G-XLam panels with a fifth of the cross-sectional thickness and twice the density of analogous cross-laminated timber exhibited an approximately two-fold increase in Ep C,0 and Ep C,90. Overall, this research provides guidelines for the assessment and standardisation of the testing procedures for similar engineered bamboo products using contact and non-contact methods and highlights the potential of using G-XLam panels in stiffness-driven applications and in combination with wood for structural purposes

Predictive factors related to the progression of periodontal disease in patients with early rheumatoid arthritis: A cohort study

Background: Rheumatoid arthritis (RA) and periodontal disease are inter-related conditions. However, factors predictive of periodontal disease progression in patients with early rheumatoid arthritis (eRA) are lacking. The aim of this study was to identify factors associated with the progression of clinical attachment loss (CAL) in interproximal dental sites of eRA patients. Methods: Twenty-eight eRA patients were evaluated for the progression of CAL at 280 interproximal dental sites at 1 year of follow-up. Markers of RA activity (rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein), a marker of bone resorption (Dickkopf-related protein 1), Disease Activity Score 28 and Simple Disease Activity Index were included as potential systemic predictive factors. Plaque index, gingival index, pocket depth, clinical attachment level and Dickkopf-related protein 1 in crevicular fluid at baseline were included as potential local predictive factors. Data were analysed in a hierarchical structure using generalised linear mixed models for progression at each site (> 2 mm) during follow-up. Results: C-reactive protein level was the most important predictive systemic factor for the progression of CAL. The mean CAL and a high degree of gingival inflammation in interproximal sites at baseline were important predictive local factors (p < 0.0001). Patients who received combined treatment with disease-modifying antirheumatic drugs and corticosteroids exhibited less CAL (p < 0.0001). The predictive value of the generalised linear mixed model for progression was 85%. Conclusions: Systemic factors, including RA disease activity and baseline periodontal condition, were associated with periodontal progression. Pharmacological treatment may affect periodontal progression in patients with early RA

Ultraestructura del complejo sinaptonémico en conejo "oryctolagus cuniculus"

El CS en conejo es descrito como una estructura constituida por tres elementos, que presentan diferentes electrodensidades al microscopio electrónico: los elementos laterales, la región central y el elemento central. Los elementos laterales se encuentran siempre asociados a la membrana nuclear a partir del leptoteno. El CS se observa totalmente formado en el paquiteno y desaparece entre el paquiteno tardio y diploteno temprano.The Synaptonemal complex (SC) of rabbit is described as a structure constituted by three elements that present different electron densities at the electron microscope: lateral elements, central region and central elemento The lateral elements are always found associated to the nuclear envelope since the leptotene stage. The SC is seen completely formed at the pachitene stage and it dessapears beetween late pachitene stage and it dissapears between late pachitene and early diplotene