130 research outputs found
Patient Satisfaction with Pharmacist Counseling
- Publication venue
- DigitalCommons@Cedarville
- Publication date
- 10/04/2013
- Field of study
A planetary-scale disturbance in a long living three vortex coupled system in Saturn's atmosphere
- Author
- Publication venue
- Elservier
- Publication date
- 22/12/2017
- Field of study
The zonal wind profile of Saturn has a unique structure at 60°N with a double-peaked jet that reaches maximum zonal velocities close to 100 ms−1. In this region, a singular group of vortices consisting of a cyclone surrounded by two anticyclones was active since 2012 until the time of this report. Our observation demonstrates that vortices in Saturn can be long-lived. The three-vortex system drifts at u = 69.0 ± 1.6 ms−1, similar to the speed of the local wind. Local motions reveal that the relative vorticity of the vortices comprising the system is ∼2–3 times the ambient zonal vorticity. In May 2015, a disturbance developed at the location of the triple vortex system, and expanded eastwards covering in two months a third of the latitudinal circle, but leaving the vortices essentially unchanged. At the time of the onset of the disturbance, a fourth vortex was present at 55°N, south of the three vortices and the evolution of the disturbance proved to be linked to the motion of this vortex. Measurements of local motions of the disturbed region show that cloud features moved essentially at the local wind speeds, suggesting that the disturbance consisted of passively advecting clouds generated by the interaction of the triple vortex system with the fourth vortex to the south. Nonlinear simulations are able to reproduce the stability and longevity of the triple vortex system under low vertical wind shear and high static stability in the upper troposphere of Saturn.This work was supported by the Spanish MICIIN projects AYA2015-65041-P (MINECO/FEDER, UE), Grupos Gobierno Vasco IT-765-13, and UFI11/55 from UPV/EHU. EGM is supported by the Serra Hunter Programme, Generalitat de Catalunya. A. Simon, K. Sayanagi and M.H. Wong were supported by a NASA Cassini Data Analysisgrant (NNX15AD33G and NNX15AD34G). We acknowledge the three orbits assigned by the Director Discretionary time from HST for this research (DD Program 14064, IP A. Sánchez-Lavega). We are very grateful to amateur astronomers contributing with their images to open databases such as PVOL (http://pvol2.ehu.eus/) and ALPO-Japan (http://alpo-j.asahikawa-med.ac.jp/)
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
- Author
- Aalfs C.M. (Cora)
- Adenis C. (Claude)
- Adlard J.W. (Julian)
- Agata S. (Simona)
- Agnarsson B.A. (Bjarni)
- Aittomäki K. (Kristiina)
- Andersen M.K. (Mette)
- Andrulis I.L. (Irene)
- Angelakos M. (Maggie)
- Antoniou A.C. (Antonis)
- Ardern-Jones A. (Audrey)
- Ardnor C.E. (Christina Edwinsdotter)
- Arnold N. (Norbert)
- Arun B.K. (Banu)
- Arver B. (Brita Wasteson)
- Asperen C.J. (Christi) van
- Attard V. (Virginia)
- Ausems M.G.E.M. (Margreet)
- Bacot F. (Francois)
- Bae-Jump V.L. (Victoria L.)
- Balmana J. (Judith)
- Bancroft E.K. (Elizabeth)
- Bardsley C. (Cathryn)
- Barjhoux L. (Laure)
- Barkardottir R.B. (Rosa)
- Barouk-Simonet E. (Emmanuelle)
- Barrowdale D. (Daniel)
- Barton D.E. (David)
- Barwell J. (Julian)
- Beattie M.S. (Mary)
- Belotti M. (Muriel)
- Benítez J. (Javier)
- Berlin C. (Cheryl)
- Berthet P. (Pascaline)
- Bignon Y.-J. (Yves-Jean)
- Bignon Y.-J. (Yves-Jean)
- Blanco I. (Ignacio)
- Blank S.V. (Stephanie)
- Blok M.J. (Marinus)
- Bock G.H. (Geertruida) de
- Bonadona V. (Valérie)
- Bonnani B. (Bernardo)
- Bonnet F. (Françoise)
- Borg Å. (Åke)
- Bourdon V. (Violaine)
- Bradshaw N. (Nicola)
- Brady A.F. (Angela)
- Bressac-de Paillerets B. (Brigitte)
- Brewer C. (C.)
- Brewer C. (Carole)
- Brice G. (Glen)
- Bronner M. (Myriam)
- Brunet J. (Joan)
- Bubien V. (Virginie)
- Buecher B. (Bruno)
- Bustinza G.B.
- Buys S.S. (Saundra)
- Caldes T. (Trinidad)
- Calender A. (Alain)
- Caligo M.A. (Maria)
- Campbell I. (Ian)
- Caron O. (Olivier)
- Castera L. (Laurent)
- Castro E. (Elena)
- Chan S. (Salina)
- Chenevix-Trench G. (Georgia)
- Chiquette J. (Jocelyne)
- Chung W.K. (Wendy)
- Claber O. (Oonagh)
- Claes K. (Kathleen)
- Cohn D.E. (David)
- Colas C. (Chrystelle)
- Cole T.J. (Trevor)
- Collier R. (Rebecca)
- Collée J.M. (Margriet)
- Cook J. (Jackie)
- Coron F. (Fanny)
- Couch F.J. (Fergus)
- Coulet F. (Florence)
- Coupier I. (Isabelle)
- Crawford G. (Gabe)
- Cronenburg T.C.T.E.F. van
- Cunningham J. (Jane)
- Daly M.B. (Mary)
- Damiola F. (Francesca)
- Damiola F. (Francesca)
- Davidson R. (Rosemarie)
- Deissler H. (Helmut)
- Delnatte C.D. (Capucine)
- Demange L. (Liliane)
- Dennis J. (Joe)
- Deurzen C.H.M. (Carolien) van
- Devilee P. (Peter)
- Devilee P. (Peter)
- Dicks E. (Ed)
- Diez O. (Orland)
- Ding Y.C. (Yuan)
- Dite G.S. (Gillian)
- Ditsch N. (Nina)
- Domchek S.M. (Susan)
- Donaldson A. (Alan)
- Dorfling C.M. (Cecelia)
- Dorkins H. (Huw)
- Douglas F. (Fiona)
- Douglas F. (Fiona)
- Dreyfus H. (Hélène)
- Drummond S. (Sarah)
- Duncan A. (Alexis)
- Dunning A.M. (Alison)
- Durda K. (Katarzyna)
- Durell S. (Sarah)
- Durán M. (Mercedes)
- Eason J. (Jacqueline)
- Easton D.F. (Douglas)
- Eccles D. (Diana)
- Eddy C. (Charlotte)
- Eeles R. (Rosalind)
- Ehrencrona H. (Hans)
- Einbeigi Z. (Zakaria)
- Eisinger F. (François)
- Ejlertsen B. (Bent)
- Ellis I.O. (Ian)
- Ellis S. (Steve)
- Ellis S.D. (Steve)
- Emanuelsson M. (Monica)
- Engel C. (Christoph)
- Engert S. (Stefanie)
- Evans D.G. (Gareth)
- Ewart-Toland A. (Amanda)
- Faivre L. (Laurence)
- Feillel V. (Viviane)
- Ferrer S.F.
- Fineberg E. (Elena)
- Fineberg E. (Elena)
- Fink-Retter A. (Anneliese)
- Foretova L. (Lenka)
- Fournier J. (Joëlle)
- Fredericksen Z. (Zachary)
- Frenay M. (Marc)
- Fricker J.P. (Jean Pierre)
- Friebel M.O.W. (Mark )
- Friedlander M. (Michael)
- Friedman E. (Eitan)
- Frost D. (Debra)
- Gadzicki D. (Dorothea)
- Ganz P.A. (Patricia)
- Garber J.
- Gaudet M.M. (Mia)
- Gauthier-Villars M. (Marion)
- Gehrig P.A. (Paola A.)
- Gerdes A-M. (Anne-Marie)
- Gibson S. (Sarah)
- Gille J.J. (Johan)
- Giraud S. (Sophie)
- Gladieff L. (Laurence)
- Glendon G. (Gord)
- Godwin A.K. (Andrew)
- Goff S. (Sheila)
- Goldgar D. (David)
- Gomez Garcia E.B. (Encarna)
- Goodman S. (Selina)
- Greene M.H. (Mark)
- Gregory H. (Helen)
- Gronwald J. (Jacek)
- Gschwantler-Kaulich D. (Daphne)
- Guimbaud R. (Rosine)
- Gómez García E.B. (Encarna)
- Hall A.S. (Alistair)
- Halliday D. (Dorothy)
- Hamann U. (Ute)
- Handallou S. (Sandrine)
- Hansen T.V.O. (Thomas)
- Haque E. (Eshika)
- Harbst K. (Katja)
- Hardouin A. (Agnès)
- hardouin A. (Agnès)
- Hart S. (Stewart)
- Healey S. (Sue)
- Henriksson K. (Karin)
- Herzog J. (Josef)
- Hodgson S.V. (Shirley)
- Hoffman J. (Jonathan)
- Hogervorst F.B.L. (Frans)
- Hooning M.J. (Maartje)
- Houdayer C. (Claude)
- Houghton C. (Catherine)
- Houlston R. (Richard)
- Hout A.H. (Annemarie) van der
- Hoya M. (Miguel) de La
- Huo D. (Dezheng)
- Huzarski T. (Tomasz)
- Imyanitov E.N. (Evgeny)
- Izatt L. (Louise)
- Izatt L. (Louise)
- Jacobs C. (Chris)
- Jakubowska A. (Anna)
- James M. (Margaret)
- James P.A. (Paul )
- Janavicius R. (Ramunas)
- Jaworska K. (Katarzyna)
- Jeffers L. (Lisa)
- Jensen U.B.
- Jernström H. (H.)
- Jobson I. (Irene)
- John E.M. (Esther)
- Jønson L. (Lars)
- Karlan B.Y. (Beth)
- Karlsson P. (Per)
- Kast K. (Karin)
- Kauff N. (Noah)
- Kaufman B. (Bella)
- Kennedy M.J. (John)
- Kets C.M. (Marleen)
- Kientz C. (Caroline)
- Killick S.R.
- Kivuva E. (Emma)
- Kohut K. (Kelly)
- Kosel M. (Matthew)
- Kristoffersson U. (Ulf)
- Kruse T.A. (Torben)
- Kuchenbaecker K.B. (Karoline)
- Kulkarni A. (Anjana)
- Kwong A. (Ava)
- Laitman Y. (Yael)
- Lalloo F. (Fiona)
- Lange J.L. (J.) de
- Langman C. (Caroline)
- Lasa A. (Adriana)
- Lasset C. (Christine)
- Lebrun M. (Marine)
- Lee A. (Andrew)
- Leeuwen F.E. (Flora) van
- Leeuwen F.E. (Flora) van
- Lehmann A. (Anna)
- Lejbkowicz F. (Flavio)
- Leroux D. (Dominique)
- Lester K.J. (Kathryn)
- Lidereau R. (Rosette)
- Liedgren S. (Sigrun)
- Ligtenberg M.J. (Marjolijn)
- Liljegren A. (Annelie)
- Lindblom A. (Annika)
- Lindor N.M. (Noralane)
- Loman N. (Niklas)
- Longmuir M. (Mark)
- Longy M. (Michel)
- Loud J.T. (Jennifer)
- Lu K.H. (Karen)
- Lubinski J. (Jan)
- Lucassen A. (Anneke)
- Luijt R.B. (Rob) van der
- Lynch H. (Henry)
- Lázaro C. (Conxi)
- Léone M. (Mélanie)
- Mai P.L. (Phuong)
- Male A. (Alison)
- Manoukian S. (Siranoush)
- Martin S. (Sue)
- Maskiell J. (Judi)
- Mazoyer S. (Sylvie)
- Mazoyer S. (Sylvie)
- McBride D. (Donna)
- McCann E. (Emma)
- McGuffog L. (Lesley)
- McLeod D. (Diane)
- Meijers-Heijboer E.J. (Hanne)
- Meijers-Heijboer H. (Hanne)
- Meindl A. (Alfons)
- Melin B. (Beatrice)
- Melloni G. (Giulia)
- Melville S.A. (Scott)
- Mensenkamp A.R. (Arjen)
- Miedzybrodzka Z. (Zosia)
- Miron A. (Alexander)
- Moeller S.T. (Sanne Traasdahl)
- Moncoutier V. (Virginie)
- Montagna M. (Marco)
- Morrison P.J. (Patrick)
- Mortemousque I. (Isabelle)
- Mourits M.J. (Marjan)
- Muller D.W. (Danièle)
- Mulligan A.M. (Anna Marie)
- Muranen T.A. (Taru)
- Murday V. (Victoria)
- Murray A. (Alexandra)
- Murray A. (Anna)
- Narod S. (Steven)
- Nathanson K.L. (Katherine)
- Neuhausen S.L. (Susan)
- Nevanlinna H. (Heli)
- Niederacher D. (Dieter)
- Niedermayr E. (Eveline)
- Nielsen F.C. (Finn)
- Noguchi T. (Tetsuro)
- Nogues C. (Catherine)
- Nordling M. (Margareta)
- Offit K. (Kenneth)
- Olah E.
- Olopade O.I. (Olofunmilayo)
- Olsson H.
- Olswold C. (Curtis)
- Ong K.-R. (Kai-Ren)
- Oosterwijk J.C. (Jan)
- Orsulic S. (Sandra)
- Os T.A.M. (Theo) van
- Os T.A.M. (Theo) van
- Osorio A. (Ana)
- Ottini L. (Laura)
- Ouweland A.M.W. (Ans) van den
- Ozcelik H. (Hilmi)
- Page E. (Elizabeth)
- Pankratz V.S. (Shane)
- Papi L. (Laura)
- Pastinen T. (Tomi)
- Paterson J. (Joan)
- Pauw A. (Antoine) de
- Pedersen I.S. (Inge Sokilde)
- Peissel B. (Bernard)
- Pensotti V. (Valeria)
- Peock S. (Susan)
- Peterlongo P. (Paolo)
- Peyrat J.-P.
- Peysselon M. (Magalie)
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- Phelan C. (Catherine)
- Piedmonte M. (Marion)
- Pigg M.H. (Maritta )
- Platte R. (Radka)
- Plendl H. (Hansjoerg)
- Porteous M.E. (Mary)
- Preisler-Adams S. (Sabine)
- Prieur F. (Fabienne)
- Pujana M.A. (Miguel)
- Pujol P. (Pascal)
- Quarrell O. (Oliver)
- Radice P. (Paolo)
- Rahman N. (Nazneen)
- Ramus S.J. (Susan)
- Randhawa K. (Kashmir)
- Rantala J. (Johanna)
- Rappaport C. (Christine)
- Rea D. (Dan)
- Rebbeck R. (Timothy)
- Rebischung C. (Christine)
- Remenieras A. (Audrey)
- Rennert G. (Gad)
- Rensburg E.J. (Elizabeth) van
- Rhiem K. (Kerstin)
- Robson M. (Mark)
- Rodriguez G.C. (Gustavo)
- Rogers M.T. (Mark)
- Romero A. (Alfonso)
- Rookus M.A. (M.)
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- Rosenquist R. (R.)
- Rouleau E. (Etienne)
- Révillion F. (Françoise)
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- Shanley S. (Susan)
- Shimon Paluch S. (Shani)
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- Simard J. (Jacques)
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- Slager S. (Susan)
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- Sobol H. (Hagay)
- Sobol H. (Hagay)
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- Soubrier F.
- Soucy P. (Penny)
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- Spurdle A.B. (Amanda)
- Stavropoulou A. (Alexandra)
- Stayner B. (Barbara)
- Steele L. (Linda)
- Stenmark-Askmalm M. (M.)
- Stevens K. (Kristen)
- Stoppa-Lyonnet D. (Dominique)
- Stoppa-Lyonnet D. (Dominique)
- Stormorken A. (Astrid)
- Sutter C. (Christian)
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- Tea M.-K.
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- Tessier Y. (Yann)
- Teulé A. (A.)
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- Tibiletti M.G. (Maria Grazia)
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- Tirapo C. (Carole)
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- Verhoef S. (S.)
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- Wachenfeldt A. (Anna) von
- Waisfisz Q. (Quinten)
- Walker L.J. (Lisa)
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- Wang C. (Chen)
- Wang X. (Xianshu)
- Wapenschmidt B. (Barbara)
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- Złowocka-Perłowska E. (Elzbieta)
- Öfverholm A. (Anna)
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 15/04/2013
- Field of study
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7×10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4×10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4×10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3b
- Author
- Abbott R.
- Abbott T.D.
- Acernese F.
- Ackley K.
- Adams C.
- Adhikari N.
- Adhikari R.X.
- Adya V.B.
- Affeldt C.
- Agarwal D.
- Agathos M.
- Agatsuma K.
- Aggarwal N.
- Aguiar O.D.
- Aiello L.
- Ain A.
- Ajith P.
- Akutsu T.
- Albanesi S.
- Allocca A.
- Altin P.A.
- Amato A.
- Anand C.
- Anand S.
- Ananyeva A.
- Anderson S.B.
- Anderson W.G.
- Ando M.
- Andrade T.
- Andres N.
- Andrić T.
- Angelova S.V.
- Ansoldi S.
- Antelis J.M.
- Antier S.
- Appert S.
- Arai Koji
- Arai Koya
- Arai Y.
- Araki S.
- Araya A.
- Araya M.C.
- Areeda J.S.
- Arellano F. E. Peña
- Aritomi N.
- Arnaud N.
- Aronson S.M.
- Arun K.G.
- Arène M.
- Asada H.
- Asali Y.
- Ashton G.
- Aso Y.
- Assiduo M.
- Aston S.M.
- Astone P.
- Aubin F.
- Austin C.
- Babak S.
- Badaracco F.
- Bader M.K.M.
- Badger C.
- Bae S.
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- Baer A.M.
- Bagnasco S.
- Bai Y.
- Baiotti L.
- Baird J.
- Bajpai R.
- Ball M.
- Ballardin G.
- Ballmer S.W.
- Balsamo A.
- Baltus G.
- Banagiri S.
- Bankar D.
- Barayoga J.C.
- Barbieri C.
- Barish B.C.
- Barker D.
- Barneo P.
- Barone F.
- Barr B.
- Barsotti L.
- Barsuglia M.
- Barta D.
- Bartlett J.
- Barton M.A.
- Bartos I.
- Bassiri R.
- Basti A.
- Bawaj M.
- Bayley J.C.
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- Bazzan M.
- Bedakihale V.M.
- Bejger M.
- Belahcene I.
- Benedetto V.
- Beniwal D.
- Bennett T.F.
- Bentley J.D.
- Benyaala M.
- Bergamin F.
- Berger B.K.
- Bernuzzi S.
- Berry C.P.L.
- Bersanetti D.
- Bertolini A.
- Betzwieser J.
- Beveridge D.
- Bhandare R.
- Bhardwaj U.
- Bhattacharjee D.
- Bhaumik S.
- Bilenko I.A.
- Billingsley G.
- Bini S.
- Birney R.
- Birnholtz O.
- Biscans S.
- Bischi M.
- Biscoveanu S.
- Bisht A.
- Biswas B.
- Bitossi M.
- Bizouard M.-A.
- Blackburn J.K.
- Blair C.D.
- Blair D.G.
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- Bobba F.
- Bode N.
- Boer M.
- Bogaert G.
- Boldrini M.
- Bonavena L.D.
- Bondu F.
- Bonilla E.
- Bonnand R.
- Booker P.
- Boom B.A.
- Bork R.
- Boschi V.
- Bose N.
- Bose S.
- Bossilkov V.
- Boudart V.
- Bouffanais Y.
- Bozzi A.
- Bradaschia C.
- Brady P.R.
- Bramley A.
- Branch A.
- Branchesi M.
- Brau J.E.
- Breschi M.
- Briant T.
- Briggs J.H.
- Brillet A.
- Brinkmann M.
- Brockill P.
- Brooks A.F.
- Brooks J.
- Brown D.D.
- Brunett S.
- Bruno G.
- Bruntz R.
- Bryant J.
- Bulik T.
- Bulten H.J.
- Buonanno A.
- Buscicchio R.
- Buskulic D.
- Bustillo J. Calderón
- Buy C.
- Byer R.L.
- Bécsy B.
- Cadonati L.
- Cagnoli G.
- Cahillane C.
- Callaghan J.D.
- Callister T.A.
- Calloni E.
- Cameron J.
- Camp J.B.
- Canepa M.
- Canevarolo S.
- Cannavacciuolo M.
- Cannon K.C.
- Canton T. Dal
- Cao H.
- Cao Z.
- Capocasa E.
- Capote E.
- Carapella G.
- Carbognani F.
- Carlin J.B.
- Carney M.F.
- Carpinelli M.
- Carrillo G.
- Carullo G.
- Carver T.L.
- Casentini C.
- Castaldi G.
- Caudill S.
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- Publication venue
- London : Institute of Physics Publ.
- Publication date
- 01/01/2022
- Field of study
We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC-2020 March 27 17:00 UTC). We conduct two independent searches: A generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate. © 2022. The Author(s). Published by the American Astronomical Society
Narrowband Searches for Continuous and Long-duration Transient Gravitational Waves from Known Pulsars in the LIGO-Virgo Third Observing Run
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- Whittle C.
- Wilken D.
- Williams D.
- Williams M.J.
- Williamson A.R.
- Willis J.L.
- Willke B.
- Wilson D.J.
- Winkler W.
- Wipf C.C.
- Wlodarczyk T.
- Woan G.
- Woehler J.
- Wofford J.K.
- Wong I.C.F.
- Wrangel J.S.A.V.
- Wu C.
- Wu D.S.
- Wu H.
- Wu S.
- Wysocki D.M.
- Xiao L.
- Xu W.-R.
- Yamada T.
- Yamamoto H.
- Yamamoto K.
- Yamamoto K.
- Yamamoto T.
- Yamashita K.
- Yamazaki R.
- Yang F.W.
- Yang L.
- Yang Y.
- Yang Y.
- Yang Z.
- Yap M.J.
- Yeeles D.W.
- Yelikar A.B.
- Ying M.
- Yokogawa K.
- Yokoyama J.
- Yokozawa T.
- Yoo J.
- Yoshioka T.
- Yu H.
- Yu H.
- Yuzurihara H.
- Zadrozny A.
- Zanolin M.
- Zeidler S.
- Zelenova T.
- Zendri J.-P.
- Zevin M.
- Zhan M.
- Zhang H.
- Zhang J.
- Zhang L.
- Zhang T.
- Zhang Y.
- Zhao C.
- Zhao G.
- Zhao Y.
- Zhao Y.
- Zhou R.
- Zhou Z.
- Zhu X.J.
- Zhu Z.-H.
- Zucker M.E.
- Zweizig J.
- Publication venue
- London : Institute of Physics Publ.
- Publication date
- 01/01/2022
- Field of study
Isolated neutron stars that are asymmetric with respect to their spin axis are possible sources of detectable continuous gravitational waves. This paper presents a fully coherent search for such signals from eighteen pulsars in data from LIGO and Virgo's third observing run (O3). For known pulsars, efficient and sensitive matched-filter searches can be carried out if one assumes the gravitational radiation is phase-locked to the electromagnetic emission. In the search presented here, we relax this assumption and allow both the frequency and the time derivative of the frequency of the gravitational waves to vary in a small range around those inferred from electromagnetic observations. We find no evidence for continuous gravitational waves, and set upper limits on the strain amplitude for each target. These limits are more constraining for seven of the targets than the spin-down limit defined by ascribing all rotational energy loss to gravitational radiation. In an additional search, we look in O3 data for long-duration (hours-months) transient gravitational waves in the aftermath of pulsar glitches for six targets with a total of nine glitches. We report two marginal outliers from this search, but find no clear evidence for such emission either. The resulting duration-dependent strain upper limits do not surpass indirect energy constraints for any of these targets. © 2022. The Author(s). Published by the American Astronomical Society
Search for gravitational-wave transients associated with magnetar bursts in advanced LIGO and advanced Virgo data from the third observing run
- Author
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- Ying M
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- Zweizig J
- Publication venue
- American Astronomical Society
- Publication date
- 01/01/2024
- Field of study
Gravitational waves are expected to be produced from neutron star oscillations associated with magnetar giant f lares and short bursts. We present the results of a search for short-duration (milliseconds to seconds) and longduration (∼100 s) transient gravitational waves from 13 magnetar short bursts observed during Advanced LIGO, Advanced Virgo, and KAGRA’s third observation run. These 13 bursts come from two magnetars, SGR1935 +2154 and SwiftJ1818.0−1607. We also include three other electromagnetic burst events detected by FermiGBM which were identified as likely coming from one or more magnetars, but they have no association with a known magnetar. No magnetar giant flares were detected during the analysis period. We find no evidence of gravitational waves associated with any of these 16 bursts. We place upper limits on the rms of the integrated incident gravitational-wave strain that reach 3.6 × 10−²³ Hz at 100 Hz for the short-duration search and 1.1 ×10−²² Hz at 450 Hz for the long-duration search. For a ringdown signal at 1590 Hz targeted by the short-duration search the limit is set to 2.3 × 10−²² Hz. Using the estimated distance to each magnetar, we derive upper limits upper limits on the emitted gravitational-wave energy of 1.5 × 1044 erg (1.0 × 1044 erg) for SGR 1935+2154 and 9.4 × 10^43 erg (1.3 × 1044 erg) for Swift J1818.0−1607, for the short-duration (long-duration) search. Assuming isotropic emission of electromagnetic radiation of the burst fluences, we constrain the ratio of gravitational-wave energy to electromagnetic energy for bursts from SGR 1935+2154 with the available fluence information. The lowest of these ratios is 4.5 × 103
Open data from the third observing run of LIGO, Virgo, KAGRA, and GEO
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- Publication venue
- American Astronomical Society
- Publication date
- 01/01/2023
- Field of study
The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages
Highly-parallelized simulation of a pixelated LArTPC on a GPU
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- Abed Abud A.
- Abi B.
- Acciarri R.
- Acero M.A.
- Adames M.R.
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2023
- Field of study
The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype
The DUNE far detector vertical drift technology. Technical design report
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- Abi B.
- Acciarri R.
- Acero M.A.
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- Adamov G.
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- Zwaska R.
- Publication venue
- IOP Publishing
- Publication date
- 01/08/2024
- Field of study
DUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi Saaïd
- Anang Abraham Kwabena
- Anas Abbad
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- Andersen Kristian
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- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
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- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
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- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
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- Batchi-Bouyou Armel L.
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- Kumordjie Selassie
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- Lemoine Frederick
- Lemtudo Alan
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- Lessells Richard
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- Ouadghiri Ouna
- Ouangole Garba
- Ouangraoua Soumeya
- Ouedraogo Abdoul-Salam
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- Pambou Mangombi
- Panja L.
- Park D.
- Park Danny
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- Pascal Butoyi
- Patel H.
- Patoo M.
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- Phiri Isaac
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- Pillay Sureshnee
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- Playle Veronica
- Poda Armel
- Pool Brigitte
- Popoola
- Povogui Moriba
- Pratt Catherine B.
- Preiser Wolfgang
- Prince-David Mireille
- Prosolek Sophie
- Puente Manoli Torres
- Quansah E.B.
- Quansah Evelyn Bonney
- Quashie P.
- Quashie Peter Kojo
- Quedraogo Rabia
- Rachakonda Sivaramakrishna
- Rachid Benhida
- Rafai Clotaire Donatien
- Rafaï Clotaire D.
- Ragomzingba Frank E. Z.
- Raharinosy Vololoniaina
- Rahoui Jalila
- Raimond Petra
- Ramadan Dalia
- Ramaologa Sefetogi
- Ramphal Upasana
- Ramphal Yajna
- Ramuth Magalutcheemee
- Ranaivoson Christian
- Ranaivoson Hafaliana C.
- Randriambolamanantsoa Tsiry
- Raouf A.
- Raoult Didier
- Rasmussen David A.
- Razafimanjato Helisoa
- Razanajatovo Norosoa H.
- Rebai Ahmed
- Reggad Ahmed
- Regragui Zakia
- Rehn A.
- Ren Xiaoyun
- René Keke K.
- Reuben Sindayiheba
- Reynders Marijke
- Reynolds Steven J.
- Rhajaoui Mohamed
- Rick S.
- Rigby Jonathan
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- Rodrigues Nadia
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- Roshdy W.H.
- Roshdy Wael H.
- Roychoudhury Pavitra
- Rubin Sarah
- Rudder Steven
- Rufael Tesfaye
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- Rujeni Nadine
- Rumunu John
- Rutayisire Robert
- Saad M.A.
- Saasa Ngonda
- Sabeti Pardis C.
- Sadeuh-Mba Serge Alain
- Sadji
- Sadji Adodo
- Sadji Y.A.
- Safer Mouna
- Safietou Sankhe
- Sahr Dumbuya Foday
- Sahr P.F.
- Saibu J.O.
- Saiid S.
- Saiid Samirah
- Saizonou Raoul
- Sakho Moustapha
- Salah D.
- Salah Djimabi
- Salah H.
- Salako Babatunde L.
- Salama Abdullah
- Saleh A.A.
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- Salifou Sourakatou
- Sall Amadou A.
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- Salma Loukman
- Salou M.
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- Samaté Dianke
- Sambou Masse
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- Sander Anna-Lena
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- Sankhe Safietou
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- Savaliya Nitin
- Sawa H.
- Sawadogo Yacouba
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- Schaffner Stephen F.
- Scharnberg Jasmin
- Scheepers Cathrine
- Schindler Tobias
- Schlotterbeck Jasmin
- Schneider Julia
- Schubert Grit
- Seadawy M.G.
- Seadawy Mohamed
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- Seadawy Mohamed Gomaa
- Sedjro Eclou
- Seffar Myriam
- Sekhsokh Yassmin
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- Semanda Patrick
- Sena Awunyo
- Sene Pauline Yacine
- Serrano Laetitia
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- Strydom Amy
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- Tefera D.A.
- Tefera Dessalegn Abeje
- Tegally Houriiyah
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- Tei-Maya
- Teka Gizaw
- Tembo John
- Tesfaye Abraham
- Tesfaye Gelanew
- Tesfaye Kassahun
- Tessema Sofonias K.
- Testimony Olumade
- Thiam Aminata Sileymane
- Thilliez Gaetan
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- Thomas Van L.
- Tia Alie
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- Tollera Getachew
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- Tomori Oyewale
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- Touzani Otmane
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- Ulrich M.
- Umumararungu Esperance
- Umuringa Jeanne d’Arc
- Upton Arlo
- Ushijima Yuri
- Ussher James
- Utpatel Christian
- Uwanibe Jessica N.
- Uwituze Arlene
- van der Eijk Annemiek
- van der Linden Anne
- van der Linden Antje
- van der Werf Sylvie
- Van Rooyen G.
- van Rooyen Gerhard
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- Vanmechelen Bert
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- von Gottberg Anne
- Waberi Zeinab Ali
- Wadi Amira Suliaman
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- Wadula J.
- Wagner Philipp
- Wahab Kolawole Wasiu
- Waitumbi John
- Walter Mathias C.
- Wamala Joseph F.
- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
- Wanjohi Dorcas W.
- Wanok Stephen
- Waruhiu C.N.
- Waruhiu Cecilia
- Wasfi Fares
- Watters Chaselynn M.
- Wawina-Bokalanga Tony
- Wayengera Misaki
- Wayoro Oby
- Webby R.
- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
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