Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin

Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest cytotoxic activities with IC50 values of 9.3 and 5.3 ug/mL on the COLO205 and KM12 cell lines, respectively. Whereas, the ethyl acetate extract of the fruits showed moderate cytotoxic activity with IC50 values of 22.3 ug/mL against the KM12 cell lines

Cytotoxicity screening of some Turkish plants against renal cancer cells

In this contribution, we performed cytotoxicity screening of 51 extracts from 17 plant species, representing 14 families growing in Turkey. Cytotoxic activities of the dichloromethane, ethyl acetate, and methanol extracts of the plants were investigated against the renal (A498 and U031) cancer cell lines. 28 extracts exhibited more than 50% growth inhibition at a 25 ug/mL concentration on both renal cancer A498 and UO31 cell lines. The extracts showed higher activity against UO31 cells than A498 cells. The dichloromethane extract of the aerial parts of Scabiosa columbaria ssp. columbaria showed the highest cytotoxic activity with 64% inhibition at a 25 ug/mL concentration on the renal cancer UO31 cell line. The methanol extract of the aerial parts of Epilobium minutiflorum showed the highest cytotoxic activity with 63% inhibition at a 25 ug/mL concentration on the renal cancer A498 cell line

Evaluation of genotype x environment interactions in maize hybrids using GGE biplot analysis

Seventeen hybrid maize genotypes were evaluated at four different locations in 2005 and 2006 cropping seasonsunder irrigated conditions in Turkey. The analysis of variance showed that mean squares of environments (E), genotypes (G) andGE interactions (GEI) were highly significant and accounted for 74, 7 and 19 % of treatment combination sum squares, respectively.To determine the effects of GEI on grain yield, the data were subjected to the GGE biplot analysis. Maize hybrid G16 can be proposedas reliably growing in test locations for high grain yield. Also, only the Yenisehir location could be best representative of overalllocations for deciding about which experimental hybrids can be recommended for grain yield in this study. Consequently, using ofgrain yield per plant instead of grain yield per plot in hybrid maize breeding programs could be preferred by private companies dueto some advantages

Books Received

WOS: 000324163700028In this study, estimation of narrow sense heritability, genetic correlations and relative effects of direct versus indirect selection were aimed for peduncle length, spike length, number of spikelet per spike and number of kernels per spike as selection was applied for shorter plant height in common wheat population of (Golia x Atilla-12) cross. While the indirect effect of direct selection for plant height was observed negative on number of kernels per spike, positive effect was obtained on peduncle length. It was understood that selection of peduncle length can be done indirectly through the selection for short plant height in the (Golia x Atilla-12), but while it had no effect on other components. Therefore, it was concluded that direct selection for short plant height can be done successfully, and on various selection practices and studies are necessary for the spike length, number of spikelet per spike and number of kernels per spike. (C) 2013 Friends Science Publisher

“Thickened” ligamentum flavum caused by laminectomy

Objective The purpose of this study was to evaluate the effect of a laminectomy on the adjacent ligamentum flavum (LF) by measuring LF thickness using magnetic resonance imaging (MRI). Materials and methods A total of 78 patients (31 man, 47 woman) with laminectomy were included in our study. After determination of laminectomy level, measurements were done from the thickest parts of the bilateral LF at the upper level of the laminectomy where bilateral facet joints were evident at the slice. Results Ipsilateral ligamentum flavum with laminectomy was significantly thicker than the contralateral ligamentum flavum with laminectomy. Conclusion Laminectomy cause thickening of ligamentum flavum. Therefore we assume that it should kept in mind that LFH may develop at the adjacent level to the laminectomy and careful clinical and radiological assessments’ should be done to exclude LFH in cases who complain about the recurrence of complaints during the post-operative period after laminectomy

Türkiye Demiryolu Yolcu Taşıma Talebinin Tahmini

Günümüzde yolcu taşımacılığında demiryollarının payı giderek artmaktadır. Yolcu talebinin karşılanması için uygun planlamaların belirlenmesi gereklidir. Kapasiteyi karşılayacak planlamaların oluşturulması hem talebi karşılayacak hem de yatırımlarda uygun kararların alınmasını sağlayacaktır. Bu çalışmada, demiryolu yolcu taşımacılığı üzerinde etkili olan değişkenler kullanılarak demiryolu yolcu sayısının tahmin edilmesi amaçlanmıştır. Yolcu talebinin belirlenmesi için Çok Değişkenli Regresyon (ÇDR) analizi ve Yapay Sinir Ağları (YSA) ile iki farklı model oluşturulmuştur. İki model içinde tahmin değerleri belirlenmiştir. Hata kareleri ortalaması (MSE) ve belirleme katsayısı (R^2), performans kriterlerini, dikkate alarak en uygun tahmin YSA ile elde edilmiştir. Talep tahmininde YSA kaynak olarak kullanılabileceği görüşüne varılmıştır

OBTAINING OF HELPFULNESS VALUE IN THE SECONDARY EDUCATION MATHEMATICS CURRICULUM BY CREATIVE DRAMA ACTIVITIES

“Values Education”, which added to Mathematics Teaching Program at the Turkish Academic Year of 2017-2018, is revised and updated as “Our Values” on January of 2018. “Our Values” based on a grown value system that aims to maintain the existence of societies preserve the unity and togetherness of societies and have the real educational success like every stage of individuals’ life. The Ministry of National Education has determined the base values, which should be gained during the education of Mathematics, as justice, friendship, honesty, patience, respect, love, responsibility, patriotism and helpfulness. The aim of this study is making the students realize their own values and making them gain the helpfulness values by using creative drama activities during the education of Mathematics. In this study, “helpfulness value”, which is under the topic of “Our Values” of Mathematics Teaching Program, was tried to put into practise by creative drama activities. In the study, experimental method which contains pretested and postested control group is used in order to show the behaviour difference between experimental group, which activity based creative drama method was applied, and the control group, which activity based creative drama method was not applied. This study is designed as a controlled experimental study with pretest-posttest. The group of study was consisted 106 students, which studying in 3 different provinces (Aydın, Afyon, Uşak) in the same region. Both experimental and control group was consisted by 53 students. In the study, data were collected from “helpfulness scale” which developed by Demirci (2017). As a result of the study, the helpfulness scale score of experimental group, which activity based creative drama was applied is high but there is no meaningful difference between helpfulness scale scores of experimental group and control group.  Article visualizations

Biological activities of the fruit essential oil, fruit, and root extracts of ferula drudeana korovin, the putative anatolian ecotype of the silphion plant

In the present study, preliminary phytochemical investigations were performed on the fruit essential oil and antioxidant-rich methanolic extracts of the fruits and roots of Ferula drudeana, the putative Anatolian ecotype of the Silphion plant, to corroborate its medicinal plant potential and identify its unique characteristics amongst other Ferula species. The essential oil from the fruits of the endemic species Ferula drudeana collected from Aksaray was analyzed by GC and GC/MS. The main components of the oil were determined as shyobunone (44.2%) and 6-epishyobunone (12.6%). The essential oil of the fruits and various solvent extracts of the fruits and roots of F. drudeana were evaluated for their antibacterial and anticandidal activity using microbroth dilution methods. The essential oil of the fruits, methanol, and methylene chloride extracts of the fruits and roots showed weak to moderate inhibitory activity against all tested microorganisms with MIC values of 78–2000 µg/mL. However, the petroleum ether extract of the roots showed remarkable inhibitory activity against Candida krusei and Candida utilis with MIC values of 19.5 and 9.75 µg/mL, respectively. Furthermore, all the samples were tested for their antioxidant activities using DPPH• TLC spot testing, online HPLC–ABTS screening, and DPPH/ABTS radical scavenging activity assessment assays. Methanolic extracts of the fruits and roots showed strong antioxidant activity in both systems

Effect of Phytohormone Applications on Fruit Yield and Essential Oil Content in Anise (Pimpinella anisum L.)

This study was carried out in 2019 to determine the effects of methyl jasmonate (MJ), gibberellic acid (GA3) and naphthalene acetic acid (NAA) applications on fruit yield and essential oil content in anise (Pimpinella anisum L.). Different concentrations of MJ (0, 0.1, 0.5 and 1 mM), GA3 (0, 50, 100 and 150 ppm) and NAA (0, 25, 50 and 100 ppm) were pulverized to the plant during the beginning of the flowering. Phytohormone applications had a statistically significant effect on the parameters examined in the study, and the effects of the applications generally varied depending on the application doses. While GA3 and NAA applications significantly increased the fruit yield and essential oil content compared to the control, high-dose MJ applications generally had a negative effect on all parameters except that the thousand-grain weight. The highest fruit yield was obtained from 100 and 150 ppm GA3 and 25 and 50 ppm NAA applications, while 1 mM MJ applications significantly reduced fruit yield compared to the control. Depending on the applications, the fruit essential oil content varied between 1.94%-2.69% and the essential oil yield varied between 1.42-3.18 L/da. While the highest essential oil yields were obtained from 100 ppm GA3 and 50 ppm NAA applications, 1 mM MJ applications caused a significant decrease in essential oil yield compared to the control