501 research outputs found
Duodenal Web and Pancreas Divisum Causing Pancreatitis in an Adult
Duodenal malformations are the third commonest cause of intestinal obstruction in infants1. A
spectrum of intrinsic obstructive lesions within the duodenum ranges from atresia to congenital bands2.
Rarely, duodenal malformations may first present in adulthood. Less than 70 cases of duodenal web
presenting in an adult have been reported in the literature. In 10 patients the presentation was associated
with pancreatitis. We report a case of congenital duodenal web associated with pancreas divisum which
first presented in an adult with the clinical characteristics of recurrent acute pancreatitis
Abdominal Wall Sinus: A Late Complication of Gallstone Spillage During Laparoscopic Cholecystectomy
Long term complications of laparoscopic cholecystectomy are uncommon. However, as experience with this procedure accumulates, sporadic reports of non-biliary complication have been published. We report a case of abdominal wall sinus formation secondary to gallbladder perforation and stone spillage occurring during laparoscopic cholecystectomy
Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit
We directly compared two methods of immortalizing human mammary epithelial cells (HMECs). Cells were transfected with an expression plasmid either for hTERT, the catalytic subunit of telomerase, or for the simian virus 40 (SV40) early region genes. Under standard culture conditions, HMECs were not immortalized by hTERT unless they had spontaneously ceased expression of the p16(INK4a) tumor suppressor gene. Untransfected HMECs had low levels of telomerase expression, and immortalization by both methods was associated with an increase in telomerase activity and prevention of telomere shortening. SV40-induced immortalization was accompanied by aberrant differentiation, loss of DNA damage response, karyotypic instability and, in some cases, tumorigenicity. hTERT-immortalized cells had fewer karyotypic changes, but had intact DNA damage responses, and features of normal differentiation. Although SV40-immortalized cells are useful for studies of carcinogenesis, hTERT-immortalized cells retain more properties of normal cells.NHMR
Laparoscopic Cholecystectomy in Cirrhotic Patient
Cholecystectomy is associated with increased risk in patients with liver cirrhosis. Moreover, cirrhosis and portal hypertension have been considered relative or absolute contraindication to laparoscopic cholecystectomy. As experience with laparoscopic cholecystectomy increased, we decided to treat cirrhotic patients via this approach. Between January 1994 and April 1995, nine patients with a Child-Pugh's stage A cirrhosis underwent elective laparoscopic cholecystectomy with intraoperative cholangiography. There was no significant per- or post-operative bleeding and no blood transfusion was necessary. There was no mortality and very low morbidity. Median hospital stay was 3 days. This series suggests that wellcompensated cirrhosis can not be considered a contraindication to laparoscopic cholecystectomy
Structure and Innervation of the Extrahepatic Biliary System in the Australian Possum, Trichosurus Vulpecula
The morphology, microanatomy and innervation of the biliary tree of the Australian possum,
Trichosurus vulpecula, was examined. The gross morphology of the gallbladder, hepatic and cystic
ducts, and the course of the common bile duct, conforms to those of other species. The sphincter of
Oddi has an extraduodenal segment that extends 15mm from the duodenal wall; within this segment the
pancreatic and common bile ducts are ensheathed together by sphincter muscle. Their lumens unite to
form a common channel within the terminal intraduodenal segment
Maxon is an Optimal Suture for Bile Duct Anastomoses in Pigs
Background. Three commonly used sutures were tested in a pig model of bile duct anastomosis to assess
their relative contributions to inflammation and scarring
Endoscopic and Surgical Management of a Hayes Type III-G Cystic Duct Anomaly Causing a Mirizzi Type I Syndrome
Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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