5 research outputs found

    Does centrality in a cross-sectional network suggest intervention targets for social anxiety disorder?

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    Objective: Network analysis allows us to identify the most interconnected (i.e., central) symptoms, and multiple authors have suggested that these symptoms might be important treatment targets. This is because change in central symptoms (relative to others) should have greater impact on change in all other symptoms. It has been argued that networks derived from cross-sectional data may help identify such important symptoms. We tested this hypothesis in social anxiety disorder. Method: We first estimated a state-of-the-art regularized partial correlation network based on participants with social anxiety disorder (n = 910) to determine which symptoms were more central. Next, we tested whether change in these central symptoms were indeed more related to overall symptom change in a separate dataset of participants with social anxiety disorder who underwent a variety of treatments (n = 244). We also tested whether relatively superficial item properties (infrequency of endorsement and variance of items) might account for any effects shown for central symptoms. Results: Centrality indices successfully predicted how strongly changes in items correlated with change in the remainder of the items. Findings were limited to the measure used in the network and did not generalize to three other measures related to social anxiety severity. In contrast, infrequency of endorsement showed associations across all measures. Conclusions: The transfer of recently published results from cross-sectional network analyses to treatment data is unlikely to be straightforward. (PsycINFO Database Record (c) 2018 APA, all rights reserved)FSW – Publicaties zonder aanstelling Universiteit Leide

    A review of photochromism in textiles and its measurement

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    Photochromism is a light-induced reversible change in colour defined as: ‘A reversible transformation in a chemical species between two forms having different absorption spectra brought about by photo-irradiation.’ This issue of Textile Progress provides a review of photochromism, the different methods for producing photochromic textiles, their properties, the measurement of kinetic colour changes, and their application in photochromic textiles. Photochromism can be utilised in a variety of textile products from everyday clothing to high-technology applications such as protective textiles, medical textiles, geo-textiles and sports textiles. Although photochromic materials have been used since 1960 to cut down the transmission of light through the lenses in sunglasses, there has been limited further development since that time due to technical difficulties not only in the application of photochromic colourants, but also with the measurement of kinetic colourchanging properties. Renewed interest in photochromic textiles has arisen due to improved commercial potential in particular for applications as photochromic nanofibres, in ‘smart’ textiles and in ‘smart’ clothing

    Current Technological Challenges in Biomarker Discovery and Validation

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