Parylene membrane slot filter for the capture, analysis and culture of viable circulating tumor cells

This paper presents a method of capturing viable circulating tumor cells (CTC) from human whole blood using constant-pressure-driven filtration through a specially designed parylene-C membrane “slot” filter. More than 90% viable cancer cells could be recovered from whole blood using the slot filter, with minimal non-cancer blood cells left on the filter. The feasibility of the telomerase activity measurement of a single cancer cell taken from the filter after capture was proven. The on-filter and off-filter cultures of the captured cancer cells were also demonstrated

Bis(2-amino­pyrimidine-κN 1)diaqua­dinitrato-κO;κ2 O,O′-cadmium(II) monohydrate

In the title compound, [Cd(NO3)2(C4H5N3)2(H2O)2]·H2O, the Cd atom is seven-coordinated by two 2-amino­pyrimidine mol­ecules, two water mol­ecules, one bidentate nitrate anion and one monodentate nitrate anion. A network of N—H⋯O, N—H⋯N and O—H⋯O hydrogen bonds helps to consolidate the crystal structure

Study on muon anomalous magnetic dipole moment in BLMSSM via the mass insertion approximation

There are 4.2 $\sigma$ deviations between the updated experimental results of muon anomalous magnetic dipole moment (MDM) and the corresponding theoretical prediction of the Standard Model (SM). We calculate the muon MDM in the framework of the MSSM extension with local gauged baryon and lepton numbers (BLMSSM). In this paper, we discuss how the muon MDM depends on the parameters in the BLMSSM in detail within the mass insertion approximation. Among the many parameters, $\tan{\beta}$, $g_L$, $m_{\lambda_L}$ and $\mu_H$ are more sensitive parameters. Considering the experimental limitations, our best numerical result of $a^{BL}_{\mu}$ is around $2.5 \times 10^{-9}$, which can well compensate the departure between the experiment data and SM prediction

Study lepton flavor violation Bd→li±lj∓B_d\rightarrow{{l_i}^{\pm}{l_j}^{\mp}} within the Mass Insertion Approximation

We study lepton flavor violating (LFV) decays $B_d\rightarrow{{l_i}^{\pm}{l_j}^{\mp}}$($B_d\rightarrow e{\mu}$, $B_d\rightarrow e{\tau}$ and $B_d\rightarrow {\mu}{\tau}$) in the $U(1)_X$SSM, which is the $U(1)_X$ extension of the minimal supersymmetric standard model(MSSM). The local gauge group of $U(1)_X$SSM is $SU(3)_C\times SU(2)_L \times U(1)_Y \times U(1)_X$. These processes are strictly forbidden in the standard model(SM), but these LFV decays are a signal of new physics(NP). We use the Mass Insertion Approximation(MIA) to find sensitive parameters that directly influence the result of the branching ratio of LFV decay $B_d\rightarrow{{l_i}^{\pm}{l_j}^{\mp}}$. Combined with the latest experimental results, we analyze the relationship between different sensitive parameters and the branching ratios of the three processes. According to the numerical analysis, we can conclude that the main sensitive parameters and LFV sources are the non-diagonal terms of the slepton mass matrix

Near tip strain evolution under cyclic loading

The concept of ratchetting strain as a crack driving force in controlling crack growth has previouslybeen explored at Portsmouth using numerical approaches for nickel-based superalloys. In this paper, we reportthe first experimental observations of the near-tip strain evolution as captured by the Digital Image Correlation(DIC) technique on a compact tension specimen of stainless steel 316L. The evolution of the near-tip strainswith loading cycles was studied whilst the crack tip was maintained stationary. The strains were monitored overthe selected distances from the crack tip for a given number of cycles under an incremental loading regime. Theresults show that strain ratchetting does occur with load cycling, and is particularly evident close to the crack tipand under higher loads. A finite element model has been developed to simulate the experiments and thesimulation results are compared with the DIC measurements

B0−B0ˉB^{0}-\bar{B^{0}} mixing in the U(1)XU(1)_XSSM

$U(1)_X$SSM is a non-universal Abelian extension of the Minimal Supersymmetric Standard Model (MSSM) and its local gauge group is extended to $SU(3)_C\times SU(2)_L \times U(1)_Y\times U(1)_X$. Based on the latest data of neutral meson mixing and experimental limitations, we investigate the process of $B^{0}-\bar{B^{0}}$ mixing in $U(1)_X$SSM. Using the effective Hamiltonian method, the Wilson coefficients and mass difference $\triangle m_{B}$ are derived. The abundant numerical results verify that $~v_S,~M^2_D,~\lambda_C,~{\mu},~M_2,~\tan{\beta},~g_{YX},~M_1$ and $~\lambda_H$ are sensitive parameters to the process of $B^{0}-\bar{B^{0}}$ mixing. With further measurement in the experiment, the parameter space of the $U(1)_X$SSM will be further constrained during the mixing process of $B^{0}-\bar{B^{0}}$

Lepton flavor violating decays lj→liγγl_j\rightarrow l_i \gamma\gamma

In this paper, we study the lepton flavor violating decays of the $l_j\rightarrow l_i \gamma\gamma$ (j=2, 3; i=1, 2) processes under the $U(1)_X$SSM. The $U(1)_X$SSM is the addition of three singlet new Higgs superfields and right-handed neutrinos to the minimal supersymmetric standard model (MSSM). Based on the latest experimental constraints of $l_j\rightarrow l_i \gamma\gamma$, we analyze the effects of different sensitive parameters on the results and made reasonable predictions for future experimental development. Numerical analysis shows that many parameters have a greater or lesser effect on lepton flavor violation(LFV), but the main sensitive parameters and sources leading to LFV are the non-diagonal elements involving the initial and final leptons. This work could provide a basis for the discovery of the existence of new physics (NP)