11 research outputs found
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
- Author
- 't Hart Ellen P.
- ?a?inková Pavla
- Aaserud Olaf
- Abbruzzese Giovanni
- Acharya T.
- Akhtar Shahbana
- Albanese Alberto
- Alegre Javier
- Alegre Javier
- Allain Philippe
- Alusi Sundus
- Amico Enrico
- Andrade Carlos
- Andrews S. C.
- Andrews Thomasin
- Andrews Thomasin
- Anheim Mathieu
- Antczak Jakub
- Armstrong Matthew
- Armstrong Richard
- Arques Penelope Navas
- Arran N.
- Arran Natalie
- Artiga María José Saiz
- Axelson E.
- Azulay Jean-Philippe
- Baake Verena
- Babiloni Blandine
- Bachoud-Lévi Anne-Catherine
- Banaszkiewicz Krzysztof
- Bandmann Oliver
- Barbera Miquel Aguilar
- Bardinet E.
- Barker Roger A.
- Barrero Francisco
- Barth Katrin
- Barth Katrin
- Barthélémy Rekha
- Bas Jordi
- Bascuñana Mónica
- Bechtel N.
- Bechtel Natalie
- Beckmann Heike
- Bek Judith
- Bellonet Marcellin
- Bentivoglio Anna Rita
- Bentivoglio Rita
- Berglund Peter
- Berna C.
- Berrissoul Hassan
- Bertini Elisabetta
- Betz Sabrina
- Biunno Ida
- Bjørgo Kathrine
- Bjørnevoll Inga
- Blaszcyk Magdalena
- Blin Stéphanie
- Bocwinska Dorota
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen S.
- Bohlen Stefan
- Bojakowska-Jaremek Kamila
- Bolwijn J. J. W.
- Bonelli Raphael
- Bonelli Raphael M.
- Bonneau Dominique
- Boogaerts Andrea
- Boogaerts Andrea
- Borowsky B.
- Bos Reineke
- Bos Reineke
- Bosca Maria E.
- Bosredon Cecile
- Bost Marie
- Boukbiza Ouhaid Lagha
- Bourne Colin
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brockie Peter
- Brugada Francisco Castera
- Brugger Florian
- Bruno Stefania
- Bryl Anna
- Buck Andrea
- Buratti Lisa
- Burguera Juan Andres
- Burgunder Jean-Marc
- Burgunder Jean-Marc
- Burgunder Jean-Marc
- Burrows Liz
- Busquets Núria
- Busse Monica
- Butcher Cynthia
- Bürk Katrin
- C Jan Frich
- Caldentey Juan Garcia
- Callaghan J.
- Callaghan Jenny
- Callaghan Jenny
- Callaghan Jenny
- Calmeyn Godelinde
- Calopa Matilde
- Campbell C.
- Campbell C.
- Campbell M.
- Campos Anabel
- Capellari Sabina
- Capetian Philipp
- Carette Maryline Cabaret Anne-Sophie
- Carrillo Fátima
- Carruesco Gemma Tome
- Cash D. M.
- Castaldo Anna
- Catena Judit López
- Chu Carol
- Chu Carol
- Chu Carol
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Clapton Jackie
- Clayton Carole
- Clenaghan Catherine
- Coelho Miguel
- Coleman A.
- Come Adrien
- Connemann Julia
- Constantinescu Radu
- Cormio Claudia
- Cortegana Hermoso Eva Pacheco
- Cortelli Pietro
- Coulthard Elizabeth
- Courtin Françoise
- Craufurd D.
- Craufurd David
- Crawford H.
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- Cáceres María Teresa
- D'Alessio Barbara
- da Silva Wildson Vieira
- Damas Fatima
- Davies Rhys
- De Bruycker Christelle
- De Michele Giuseppe
- de Souza Jenny
- de Tommaso Marina
- de Weert A. Marit
- de Yébenes Justo García
- de Yébenes Justo García
- Debruxelles Sabrina
- Dec Malgorzata
- Decolongon J.
- Defebvre Eric Decorte Luc
- Dekker M.
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Delvaux Isabelle
- Descals Asunción Martínez
- Destee Alain
- Di Bella Daniela
- Di Donato Stefano
- Di Maio Luigi
- Di Pietro Anna
- di Poggio Monica Bandettini
- Di Renzo Martina
- Diercks Gabriele
- Dipple Heather
- Dixon Kathryn
- Doherty Karen
- Dose Matthias
- Dougherty Andrew
- Dressler Dirk
- Duché Charlotte
- Dujardin Kathy
- Dumas E. M.
- Dumas Eve M.
- Dunnett Stephen
- Dunnett Stephen
- Dupuit Michel
- Durr Alexandra
- Duru Cécile
- Dziadkiewicz Artur
- Ecker Daniel
- Ecker Daniel
- Edwards Maureen
- Ellrichmann Gisa
- Esposito Chiara
- Eusebio Alexandre
- Evans Carole
- Fairtlough Helen
- Fannemel Madeleine
- Fasquel Véronique
- Favellato Mariagrazia
- Fenollar María
- Ferrandes Giovanna
- Ferreira Joaquim
- Ferreira Joaquim J.
- Ferrer Pilar Quiléz
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Fletcher Amy
- Fluchere Frédérique
- Fortuna Lorenza
- Foster Jillian
- Foustanos Isabella
- Fox N. C.
- Foy Kevin
- Frajman E.
- Frech Fernando Alonso
- Fredlund Gunnel
- Freire-Patino Dawn
- Frontali Marina
- Frost C.
- Fullam Ruth
- Fullam Ruth
- Fullam Ruth
- Gago Miguel
- Galassi Roberto
- Gallantrae Deena
- Gallentrae Deena
- Ganos Christos
- Garcia Patrocinio Moreno
- García Rocío García-Ramos
- Garde Monica Bascuñana
- Garrett Carolina
- Gaston Itziar
- Geitner Carolin
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Gerrans Emily
- Gethin Louise
- Ghelli Elena
- Gibbard C.
- Gill Paul
- Gilling Mette
- Ginestroni Andrea
- Godefroy Olivier
- Gogol Anna
- Gohier Bénédicte
- Goizet Cyril
- Golding Charlotte
- Golding Charlotte
- Gonzenbach Roman
- González González Sonia
- Goodman Anna
- Gorospe Aranzazú
- Gorzkowska Agnieszka
- Gorzolla Heike
- Grant Janet
- Griguoli Annamaria
- Gross Diana
- Guedes Leonor Correia
- Guedes Leonor Correia
- Guerra Maria Rosália
- Guerrero Rosa
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guisasola Luis Menéndez
- Gustafsson Lena
- Guzman Natalie Valle
- Guérid Marie-Anne
- Gørvell Per F.
- Haider Salman
- Hallam Caroline
- Hamer Stephanie
- Hamer Stephanie
- Hamer Stephanie
- Hametner Eva-Maria
- Handley Olivia
- Handley Olivia
- Handley Olivia J.
- Harding Alison
- Hare Marianne
- Harrison David
- Hauer Maria
- Hayward Beverley
- Hecht Karen
- Heiberg Arvid
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Held Christine
- Hensman Moss Davina J.
- Hensman Davina
- Hepperger Caroline
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Durán
- Herrmann Lennard
- Hicks S.
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Hjermind Lena E.
- Ho Carrie
- Hobbs N.
- Hobson Emma
- Hoffmann Rainer
- Holas Christiane
- Holl Anna
- Holmans Peter
- Hotter Anna
- Howard Liz
- Hughes Max
- Hughes Teresa
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Hvalstedt Carina
- Hyppönen Hannele
- Hölzner Eva
- Høsterey-Ugander Ulrika
- Ialongo Tamara
- Idiago Jesús Miguel Ruiz
- Illmann Torsten
- Jachinska Katarzyna
- Jack Roisin
- Jacobsen Oda
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Jasinska-Myga Barbara
- Johns Nicola
- Johnson H.
- Johnson Liz
- Jones Lesley
- Jones Lesley
- Jones Mary
- Jones R.
- Jones Una
- Julié Celine
- Jung Hans H.
- Jurgens C.
- Justo D.
- Kaelin Alain
- Kaminski Barbara
- Kapfhammer Hans-Peter
- Kavalier Fred
- Kazoka Mbombe
- Keenan S.
- Kennard C.
- Kershaw Ann
- Kesse Andrea
- Khalil Hanan
- Klempír Jirí
- Klimberg Aneta
- Klodowska-Duda Gabriela
- Klöppel Stefan
- Koivisto Susana Pro
- Koivisto Susana Pro
- Koivisto Susana Pro
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kotz Peter
- Kraus Alison
- Kraus Alison
- Kraus Alison
- Kraus P.
- Krawczyk Malgorzata
- Kremer B.
- Kremer Berry
- Krysa Wioletta
- Krystkowiak Pierre
- Kwiecinski Hubert
- Labuschagne I.
- Lafoucrière Danielle
- Lahiri N.
- Lahiri Nayana
- Laing Hana
- Lamanna Claudia
- Lambeck Johann
- Landwehrmeyer B.
- Landwehrmeyer Bernhard
- Landwehrmeyer G. Bernhard
- Lang Christina
- Langbehn Douglas
- Lange Herwig
- Lange Herwig
- Larsen Ida Unmack
- Lashwood Alison
- Lau Puay Ngoh
- Laurà Matilde
- Laver Fiona
- Leavitt Blair R.
- Lee S.
- Leenders K. L.
- Lehericy S.
- Lemaire Marie-Hélène
- Levey Jamie
- Lewerenz Jan
- Lewerenz Jan
- Lewis Monica
- Lewis Monica
- Leythäuser Gabriele
- Lezius Franziska
- Liessens Dirk
- Lilek Sabine
- Linnsand Petra
- Lo Kitty
- Longato Nadine
- Longinus Bernhard
- Longthorpe Mandy
- Lopera Mónica Rodriguez
- Lorentzen Eirin
- Loutfi Ghada
- Lucena Carolina Mendez
- Löhle Matthias
- Maass Antonia
- Magnet Markus
- Maiwald Robert
- Majerová Veronika
- Malone I.
- Man A. Hoff
- Mandich Paola
- Manouvrier Sylvie
- Mantaux Béatrice
- Manzanares Salvadora
- Marchese Roberta
- Marcinkowski Jerzy
- Marelli C.
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Markova Ivana
- Markova Ivana
- Marquard Ralf
- Martikainen Kirsti
- Martinez-Horta Saül
- Martinez-Jaurrieta Maria Dolores
- Martín Esther Suaréz San
- Martínez-Descals Asunción
- Mason Sarah
- Massarelli Marco
- Massaro Francesca
- Matheson Kirsty
- Mazzante Irene
- McGill Marie
- McKenzie Sue
- Mead Simon
- Mechi Claudia
- Mendes Tiago
- Mestre Tiago
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Mihaylova Violeta
- Milchman C.
- Milkereit Eva
- Minet Cécile
- Minster Sara
- Minster Sara
- Mir Pablo
- Monaco W.
- Monza Daniela
- Monza Daniela
- Morales Blas
- Moreau Laura Vivancos
- Moreno Jose Manuel Garcia
- Moreno José Luis López-Sendón
- Mundler Laura
- Murch Ann
- Murphy Helen
- Musgrave Hannah
- Möller Jens Carsten
- Mühlau Mark
- Müller Christoph
- Müller Nicole
- Münchau Alexander
- Mütze Lisanne
- Nanetti Lorenzo
- Neleborn-Lingefjärd Liselotte
- Nemeth Andrea H.
- Nepper Solveig
- Nielsen Jørgen
- Nielsen Jørgen E.
- Niess Anke
- Nigaud K.
- Novak Marianne
- Nowak Malgorzata
- O'Donovan Kirsty
- O'Keefe Deidre
- O'Regan A.
- Oehmen Martin
- Olivier Audrey
- Olofsson Carina
- Opala Gregorz
- Ordidge R.
- Ortega Paloma
- Orth Michael
- Orth Michael
- Orth Michael
- Otti Daniela
- Oughton Emma
- Owen G.
- Owen Michael
- Padieu Hélène
- Paganini Marco
- Painold Annamaria
- Pardiñas Antonio F.
- Paridi Dominga
- Parkinson Andrew
- Partington-Jones Lucy
- Pastor Barbara Vives
- Pate Louise
- Patel A.
- Patel Aakta
- Paterski Laurent
- Paterson Nicole
- Pearson Pauline
- Peinemann Alexander
- Peluso Silvio
- Peppa Nadia
- Peppa Nadia
- Pepple T.
- Perea María Fuensanta Noguera
- Peter Mireille
- Petersen Jens
- Petrollini Martina
- Peña José Chacón
- Piacentini Silvia
- Piano Carla
- Pica Emmanul
- Piedad John
- Plomhouse Lucie
- Poda Roberto
- Poewe Werner
- Polo Cecilia Gil
- Porteous Mary
- Pourchot C.
- Pradella Silvia
- Prehn Christian
- Price Kathleen
- Priller Josef
- Probst Daniela
- Prundean Adriana
- Prüß Harald
- Päivärinta Markku
- Quarrell Oliver
- Queller S.
- Raab Tina
- Rae Daniela
- Rakowicz Maryla
- Raman Ashok
- Raman Ashok
- Raman Ashok
- Ramirez Inés Legarda
- Ramos-Arroyo Maria A.
- Ramos-Arroyo Maria A.
- Raymond Lucy
- Read J.
- Redondo Luis
- Reetz Kathrin
- REGISTRY investigators
- Reilmann R.
- Reilmann Ralf
- Reinante Gema
- Reisinger Karin
- Ret C. Jauff
- Retterstøl Lars
- Rialland Amandine
- Riballo Antonio Villa
- Ribas Guillermo García
- Ribaï Pascale
- Ribbat Michael
- Richter Przemyslaw
- Rickards Hugh
- Rissling Ida
- Rivadeneyra Perez Jessica
- Rizzo Giovanni
- Robert Misericordia Floriach
- Robertson Dene
- Robertson Nicola
- Robertson Nicola
- Robowski Piotr
- Roca Alessandro
- Rodríguez María José Torres
- Rogers Dawn
- Rohm Stefanie
- Rola Rafal
- Romano Silvia
- Romero Irene
- Romoli Anna Maria
- Roos Raymund
- Roos Raymund A. C.
- Roos Raymund A. C.
- Rosas H. D.
- Rosser Anne
- Rosser Elisabeth
- Roth Jan
- Rothery Jean
- Roussel Martine
- Rowett Liz
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzinska Monika
- Rumpf Silke
- Russo Cinzia Valeria
- Ruíz Pedro J. García
- Ryglewicz Danuta
- Røren Niini
- Sablonnière Bernard
- Saft Carsten
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- Sando Sigrid Botne
- Santhouse Alastair
- Santos R. Dar
- Sass Christian
- Say M.
- Scaglione Cesa
- Scahill R.
- Scheibl Monika
- Schepers Sigrun
- Scherer-Gagou Clarisse
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schneider Ariane
- Schrader Christoph
- Schwenk Daniela
- Schöggl Helmut
- Schüpbach Michael
- Sciruicchio Vittorio
- Sebastián A. Rojo
- Sebastián Ana Rojo
- Sempolowicz Justyna
- Seppi Klaus
- Serpino Claudia
- Sienkiewicz-Jarosz Halina
- Sieradzan Kasia
- Silva Mark
- Simonin Clémence
- Simpson Sheila A.
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Smith Paul
- Snowden Julie
- Soleti Francesco
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltysiak Beverley
- Somers Nele
- Sorbi Sandro
- Sorrentino Pierpaolo
- Spadaro Maria
- Spampinato Umberto
- Sprenger Fabienne
- Spruth Eike Jakob
- Squitieri Ferdinando
- Stattin Eva-Lena
- Stebler Yanik
- Stepniak Iwona
- Stokke Bodil
- Stompel Daniel
- Stopford C.
- Stopford Cheryl
- Storch Alexander
- Stout J.
- Stubbe Lars
- Sturrock A.
- Stárková Irena
- Städtler Michael
- Suarez María José Lama
- Sulek Anna
- Summers Fiona
- Swain Rachel
- Szczudlik Andrzej
- Szczygiel Elzbieta
- Szinwelski Michal
- Sánchez Vicenta
- Süßmuth Sigurd
- t'Hart E. P.
- Tabrizi Sarah
- Tabrizi Sarah
- Tabrizi Sarah J.
- Tacik Pawel
- Tan Louis
- Taylor Cat
- Taylor Rachel
- Thibault-Tanchou Stéphanie
- Thomas Gareth
- Thompson Catherine
- Thompson Jennifer
- Thomson Aileen
- Tidswell Katherine
- Timewell Erika
- Tobin A.
- Tomasello Chiara
- Torres María Martirio Antequera
- Toscano Jean
- Townhill Jenny
- Townhill Jenny
- TRACK-HD investigators
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhard Iris
- Tuuha Katri
- Uhrova Tereza
- Ullah Jasmin
- Ure Alexandra
- Valabrègue R.
- Valadas Anabela
- Valentine Ruth
- van den Bogaard S. J. A.
- van den Bogaard Simon J. A.
- van der Grond J.
- van Hout Monique S. E.
- van Oostrom J. C. H.
- van Paemel Dominique
- van Reijen Dimphna
- van Vugt Jeroen P. P.
- van Walsem Marleen R.
- van Walsem Marleen R.
- Vandenberghe Wim
- Vandenberghe Wim
- Vargas-González Laura
- Vaughan Vivien
- Ventura Marta Fatás
- Verellen-Dumoulin Christine
- Verellen-Dumoulin Christine
- Verhoeven Marloes E.
- Verny Christophe
- Verstappen C. C. P.
- Verstraelen Nichola
- Viladrich Celia Mareca
- Vilaplana Garcia Carmen Peiró
- Villanueva Clara
- Vinther-Jensen Tua
- Vuillaume Isabelle
- Wahlström Jan
- Wahlström Jan
- Wang C.
- Wannepain Sandrine
- Warner Thomas
- Wasielewska Anna
- Weber Zaugg Sabine
- Weber Natalia
- Wehus Ragnhild
- Weindl Adolf
- Wenning Gregor
- Wentzel Magnus
- Werner Cornelius J.
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Whalstedt Carina
- Whitehead D.
- Whitlock K.
- Wiedemann Alexandra
- Wikström Birgitta
- Wild E.
- Wild Edward
- Wild Sue
- Wild Sue
- Winkelmann Juliane
- Witjes-Ane M.-N.
- Witjes-Ané Marie-Noelle
- Witkowski Grzegorz
- Witkowski Grzegorz
- Wolz Annett
- Wolz Martin
- Wright Abigail
- Wright Abigail
- Wright Jan
- Wójcik Magdalena
- Yardumian Pam
- Yardumian Pam
- Yates Shona
- Zaremba Jacek
- Zaremba Jacek
- Zdzienicka Elzbieta
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Daniel
- Zielonka Eugeniusz
- Zieora-Jakutowicz Karolina
- Zimmermann Marie-Agathe
- Zinzi Paola
- Zinzi Paola
- Zittel Simone
- Zucker Birgit
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Background Huntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT. Age at onset has been used as a quantitative phenotype in genetic analysis looking for Huntington's disease modifiers, but is hard to define and not always available. Therefore, we aimed to generate a novel measure of disease progression and to identify genetic markers associated with this progression measure. Methods We generated a progression score on the basis of principal component analysis of prospectively acquired longitudinal changes in motor, cognitive, and imaging measures in the 218 indivduals in the TRACK-HD cohort of Huntington's disease gene mutation carriers (data collected 2008–11). We generated a parallel progression score using data from 1773 previously genotyped participants from the European Huntington's Disease Network REGISTRY study of Huntington's disease mutation carriers (data collected 2003–13). We did a genome-wide association analyses in terms of progression for 216 TRACK-HD participants and 1773 REGISTRY participants, then a meta-analysis of these results was undertaken. Findings Longitudinal motor, cognitive, and imaging scores were correlated with each other in TRACK-HD participants, justifying use of a single, cross-domain measure of disease progression in both studies. The TRACK-HD and REGISTRY progression measures were correlated with each other (r=0·674), and with age at onset (TRACK-HD, r=0·315; REGISTRY, r=0·234). The meta-analysis of progression in TRACK-HD and REGISTRY gave a genome-wide significant signal (p=1·12 × 10−10) on chromosome 5 spanning three genes: MSH3, DHFR, and MTRNR2L2. The genes in this locus were associated with progression in TRACK-HD (MSH3 p=2·94 × 10−8 DHFR p=8·37 × 10−7 MTRNR2L2 p=2·15 × 10−9) and to a lesser extent in REGISTRY (MSH3 p=9·36 × 10−4 DHFR p=8·45 × 10−4 MTRNR2L2 p=1·20 × 10−3). The lead single nucleotide polymorphism (SNP) in TRACK-HD (rs557874766) was genome-wide significant in the meta-analysis (p=1·58 × 10−8), and encodes an aminoacid change (Pro67Ala) in MSH3. In TRACK-HD, each copy of the minor allele at this SNP was associated with a 0·4 units per year (95% CI 0·16–0·66) reduction in the rate of change of the Unified Huntington's Disease Rating Scale (UHDRS) Total Motor Score, and a reduction of 0·12 units per year (95% CI 0·06–0·18) in the rate of change of UHDRS Total Functional Capacity score. These associations remained significant after adjusting for age of onset. Interpretation The multidomain progression measure in TRACK-HD was associated with a functional variant that was genome-wide significant in our meta-analysis. The association in only 216 participants implies that the progression measure is a sensitive reflection of disease burden, that the effect size at this locus is large, or both. Knockout of Msh3 reduces somatic expansion in Huntington's disease mouse models, suggesting this mechanism as an area for future therapeutic investigation
NMDA receptor gene variations as modifiers in Huntington disease: a replication study.
- Author
- Abbruzzese G
- Aguilar Barbera M
- Albanese A
- Alberti S
- Andrews T
- Andrews T
- Antczak J
- Arning Larissa
- Arran N
- Badenes Guia D
- Banaszkiewicz K
- Bandettini di Poggio Giovanna Ferrandes M
- Bandmann O
- Barker R
- Barrero F
- Barth K
- Bas J
- Bascuñana Garde M
- Bascuñana Garde M. Collaborators Barth K
- Bascuñana M
- Beister A
- Beister A
- Bentivoglio A
- Bertini E
- Bisson J
- Björnsson E
- Bjørgo K
- Bjørnevoll I
- Boczarska Jedynak M
- Bohlen S
- Bolwijn JJ
- Bonelli R
- Bos R
- Bos R
- Botne Sando S
- Bourne C
- Bradbury A
- Brugger F
- Bruno S
- Bryl A
- Burgunder JM
- Burrows L
- Busquets N
- Busse M
- Calopa M
- Carrillo F
- Casas Hernanz L
- Chu E
- Ciesielska A
- Clapton J
- Clayton C
- Codella V
- Coelho M
- Cormio C
- Craufurd D
- Craufurd David
- Cubo E
- De Gregorio F
- De Michele G
- De Nicola N
- De Sousa P
- de Souza J
- de Tommaso M
- DE TOMMASO Marina
- de Yebenes Justo Garcia
- de Yébenes JG
- Dekker M
- Di Donato S
- Di Maria E
- Difruscolo O
- Dipple H
- Doherty K
- Dose M
- Dose M
- Dose Matthias
- Dougherty A
- Dumas E
- Dunnett S
- Ecker D
- Ecker D
- Edwards M
- Ellison Rose L
- Epplen Null
- Eschenbach C
- Fannemel M
- Fasano A
- Fatàas M
- Ferreira J
- Fillingham K
- Fisher K
- Fletcher A
- Fortuna Alcaraz L
- Foustanos I
- Frontali M
- Fuensanta Noguera Perea M
- Fullam R
- Gago M
- García R
- García Ribas G
- García Ruíz P
- Garrett C
- Gellera C
- Golding C
- Gorospe A
- Goyder Goodman A
- Grant J
- Gross D
- Guerra M
- Guidubaldi A
- Gørvell P
- Hallam C
- Hammer K
- Hammer K
- Handley O
- Handley O
- Hasholt L
- Heiberg A
- Heinicke W
- Heinonen N
- Held C
- Hepperger C
- Herranhof B
- Hiivola H
- Hill S
- Hjermind L
- Hotter A
- Howard L
- Hughes T
- Hunt S
- Huson S
- Hödl A
- Ialongo T
- Jachinska K
- Jacopini G
- Jakobsen O
- Jamrozik Z
- Janik P
- Jasinska Myga B
- José Lama Suarez M
- José Saiz Artiga M
- José Torres Rodríguez M
- Jurgens C
- Kalbarczyk A
- Kapfhammer HP
- Kavalier F
- Kershaw A
- Klempíř J
- Klimberg A
- Koppitz M
- Kosinski C
- Krawczyk M
- Kremer B
- Kucharik M
- Kwiecinski H
- Lahiri N
- Lambeck J
- Lambord N
- Landwehrmeyer B
- Landwehrmeyer G. Bernhard
- Lange H
- Lange H
- Lashwood A
- Laurà M
- Laver F
- Leenders KL
- Legarda I
- Leythaeuser G
- Leythaeuser G
- Lezius F
- Longinus B
- Loria G
- Loutfi G
- Luigi D
- Luis López Moreno J
- López Catena J
- López Sendón Moreno J
- Löhle M
- Maglione V
- Magnet M
- Mahlknecht P
- Mandich P
- Marchese R
- Marcinkowski J
- Mariotti C
- Mariscal N
- Marit de Weert A
- Marquard R
- Marquard R
- Martikainen K
- Martino T
- Martirio Antequera Torres M
- Martínez Descals A
- Martínez Descals A
- Mason S
- McGill M
- Mechi C
- Mestre T
- Mestre T
- Middleton J
- Mir P
- Monza D
- Monza D
- Morales B
- Murch A
- Münchau A
- Naji J
- Naji J
- Nanetti L
- Navas Arques P
- Nemeth A
- Nielsen J
- Nocker M
- Novak M
- Nørremølle A
- Opala G
- Orobello S
- Orth M
- Orth M
- Otti D
- Padieu H
- Paganini M
- Painold A
- Partington Jones L
- Patel A
- Paterson N
- Patino D
- Patterson M
- Patton M
- Pearson P
- Peinemann A
- Piacentini S
- Piano C
- Pin Quiroga P
- Porteous M
- Price K
- Pro Koivisto S
- Probst D
- Pålhagen S
- Quarrell O.
- Raab T
- Raab T
- Rakowicz M
- Rankin J
- Raymond L
- Reilmann R
- Reisinge K
- Retterstøl L
- Rialland A
- Ribaï P
- Richter P
- Rickards H
- Rinaldi C
- Robertson D
- Rojo Sebastian A
- Romano S
- Romero I
- Romoli M
- Roos R
- Roos Raymund A. C.
- Rosa M
- Rosser A
- Roth J
- Ruddy D
- Rudzińska M
- Russo C
- Ryglewicz D
- Saft Carsten
- Salvatore E
- Sasinková P
- Sass C
- Schiefer J
- Schlangen C
- Schrenk C
- Schrenk C
- Schuierer M
- Schuierer M
- Schwarz C
- Schüpbach M
- Sciruicchio V
- Sempołowicz J
- Seppi K
- Serpino C
- Silva M
- Sitek E
- Siuda G
- Slawek J
- Smith P
- Snowden J
- Soleti F
- Soliveri P
- Sollom A
- Soltan W
- Sorbi S
- Spadaro M
- Squitieri F
- Stattin EL
- Stokholm J
- Stopford C
- Storch A
- Stubbe L
- Städtler M
- Suarez San Martin E
- Szczudlik A
- Sánchez J
- Sánchez V
- Sørensen S
- Tabrizi S
- Tabrizi Sarah J
- Taylor R
- Thompson J
- Thomson A
- Tidswell K
- Tomasello C
- Tome Carruesco G
- Trautmann S
- Trigo Cubillo P
- Trigo Cubillo P
- Tucci T
- Tuuha K
- Valadas A
- van den Bogaard SA
- van Hout M
- van Oostrom JC
- van Vugt J
- van Walsem M
- van Walsem M
- Verellen Dumoulin C
- Verstappen CC
- Verstraelen N
- Villanueva C
- Vivancos Moreau L
- Vives B
- Warner T
- Weber Zaugg S
- Weindl A
- Wenning G
- Werner C
- Westman L
- Westmoreland L
- Whaite A
- Wieczorek Stefan
- Wiedemann A
- Wiedemann A
- Wikström B
- Wild E
- Witjes Ané MN
- Witjes Ané MN
- Witkowski G
- Wolz A
- Wolz M
- Wright J
- Wójcik M
- Zaremba J
- Zdzienicka E
- Zeman A
- Zielonka D
- Zielonka D
- Zinzi P
- Zittel S
- Zucker B
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2011
- Field of study
Several candidate modifier genes which, in addition to the pathogenic CAG repeat expansion, influence the age at onset (AO) in Huntington disease (HD) have already been described. The aim of this study was to replicate association of variations in the N-methyl D-aspartate receptor subtype genes GRIN2A and GRIN2B in the “REGISTRY” cohort from the European Huntington Disease Network (EHDN). The analyses did replicate the association reported between the GRIN2A rs2650427 variation and AO in the entire cohort. Yet, when subjects were stratified by AO subtypes, we found nominally significant evidence for an association of the GRIN2A rs1969060 variation and the GRIN2B rs1806201 variation. These findings further implicate the N-methyl D-aspartate receptor subtype genes as loci containing variation associated with AO in HD
Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease.
- Author
- Abbruzzese G
- Aguilar Barbera M
- Albanese A
- Andrews T
- Andrews T
- Andrich J
- Antczak J
- Arran N
- Aziz NA
- Bachoud-Levi A-C
- Badenes D
- Bandmann O
- Barker RA
- Barrero FJ
- Barth K
- Bas J
- Bascunana M
- Beister A
- Bentivoglio AR
- Bentivoglio AR
- Bertini E
- Bisson J
- Biunno I
- Bjorgo K
- Bjornevoll I
- Bohlen S
- Bolwijn JJW
- Bonelli R
- Bonelli RM
- Bos R
- Bos R
- Bourne C
- Bradbury A
- Brockie P
- Bruno S
- Bryl A
- Burgunder J-M
- Burgunder J-M
- Burrows L
- Busse M
- Calopa M
- Carlo R
- Casas L
- Chu C
- Ciarmiello A
- Ciesielska A
- Clayton C
- Coelho M
- Costa C
- Craufurd D
- Cubillo PT
- Cubo E
- Curtis A
- De Michele G
- de Raedt S
- De Sousa PA
- Dekker M
- Descals AM
- Di Donato S
- Dipple H
- Dose M
- Dougherty A
- Dumas E
- Dunnett SB
- Ecker D
- Ecker D
- Edwards M
- Ellison-Rose L
- Escalante Arroyo S
- Fannemel M
- Fasano A
- Fatas M
- Ferrandes MBDPG
- Ferreira JJ
- Ferreira JJ
- Fillingham K
- Fisher K
- Flamez A
- Fletcher A
- Foster J
- Foustanos I
- Frontali M
- Fullam R
- Gago M
- Garcia de Yebenes J
- Garcia Ribas G
- Garcia Ruiz-Espiga P-J
- Garcia-Ramos Garcia R
- Garde MB
- Garrett C
- Gaston I
- Golding C
- Golding C
- Goodman AOG
- Gorospe A
- Gorvell P
- Grant J
- Gross D
- Guerra MR
- Guidubaldi A
- Hallam C
- Handley O
- Handley OJ
- Handley OJ
- Handley OJ
- Hasholt L
- Heiberg A
- Heiberg A
- Heinicke W
- Heinonen N
- Held C
- Henley S
- Hernandez Vara J
- Herranhof B
- Hidding U
- Hiivola H
- Hill S
- Hjermind LE
- Ho A
- Hobson E
- Hoedl A
- Hoffmann R
- Howard L
- Hughes T
- Hunger U
- Huson S
- Ialongo T
- Illman T
- Jacopini G
- Jakobsen O
- Jamieson S
- Jamrozik Z
- Janik P
- Johns N
- Jurgens CK
- Jurgens CK
- Kalbarczyk A
- Kavalier F
- Kershaw A
- Keylock J
- Klimberg A
- Koivisto SP
- Koppitz M
- Kosinski CM
- Kozubski W
- Kraus P
- Krupinski J
- Kwiecinski H
- Lammbeck J
- Landwehrmeyer B
- Landwehrmeyer GB
- Landwehrmeyer GB
- Lange H
- Lange H
- Lashwood A
- Laura M
- Laver F
- Leenders KL
- Legarda I
- Levey J
- Leythaeuser G
- Lezius F
- Loehle M
- Longinus B
- Lopez del Val J
- Lopez Moreno JL
- Lopez J
- Lopez-Sendon Moreno JL
- Loria G
- Luigi DM
- Magnet M
- Mandes P
- Marchese R
- Marcinkowski J
- Mariotti C
- Mariscal N
- Marit de Weert A
- Marquard R
- Martikainen K
- Martinez A
- Martinez L
- Martino T
- Mason S
- Matheson K
- McGill M
- McKenzie S
- Mechi C
- Mestre T
- Mestre T
- Middleton J
- Moeller JC
- Monza D
- Morales B
- Morez V
- Muenchau A
- Murch A
- Naji J
- Naji J
- Navas Arques P
- Nemeth AH
- Nielsen JE
- Norremolle A
- O'Driscoll C
- Obdulia M
- Orth M
- Orth M
- Otti D
- Padieu H
- Paganini M
- Painold A
- Paivarinta M
- Partington-Jones L
- Patel A
- Paterson N
- Pearson P
- Peinemann A
- Peippo M
- Piacentini S
- Piano C
- Pin Quiroga P
- Porteous M
- Prehn C
- Price K
- Priller J
- Probst D
- Pruess H
- Quarrell O
- Quilez Ferrer P
- Rae D
- Rakowicz M
- Ramos-Arroyo MA
- Raymond L
- Reilmann R
- Reisinger K
- Retterstol L
- Reynders H
- Rialland A
- Ribai P
- Richter P
- Rickards H
- Rinaldi C
- Rissling I
- Ritchie N
- Robertson D
- Robertson L
- Rojo Sebastian A
- Romano S
- Romero Contreras S
- Romero I
- Romoli M
- Roos RAC
- Roos RAC
- Roos RAC
- Rosa MM
- Rosser A
- Rosser E
- Ruddy D
- Rudzinska M
- Ryglewicz D
- Saft C
- Saiz Artiga MJ
- Salmen S
- Salvatore E
- Sanchez J
- Sanchez V
- Sando SB
- Sasinkova P
- Sass C
- Schiefer J
- Schlangen C
- Schmidt S
- Schrenk C
- Schuepbach M
- Schuierer M
- Schwarz C
- Schwenke C
- Sebastian AR
- Sempolowicz PJ
- Silva M
- Simonelli M
- Simpson S
- Sipponen M
- Sitek EJ
- Siuda G
- Slawek J
- Snowden J
- Soleti F
- Soliveri P
- Solom A
- Soltan W
- Sorbi S
- Sorensen SA
- Spadaro M
- Squitieri F
- Staedtler M
- Stijnen T
- Stokholm J
- Stopford C
- Storch A
- Strassburger K
- Stubbe L
- Summers F
- Szczudlik A
- Tabrizi S
- Tabrizi SJ
- Tabrizi SJ
- Taylor R
- Thomas G
- Thompson J
- Thomson A
- Tidswell K
- Tome Carruesco G
- Torres Rodriguez MJ
- Toscano J
- Trautmann S
- Trigo Cubillo P
- Tucci T
- Tuuha K
- Uhrova T
- Ure A
- Valadas A
- van Hout MSE
- van Ommen GJB
- van Oostrom JCH
- van Reijen D
- van Roon-Mom WMC
- van Vugt JPP
- van Walsem M
- van Walsem MR
- Vandenberghe W
- Vandenberghe W
- Verellen-Dumoulin C
- Verellen-Dumoulin C
- Villanueva C
- Wahlstrom J
- Wallner M
- Warner T
- Weindl A
- Werner CJ
- Westmoreland L
- Whaite A
- Wiedemann A
- Wild E
- Wild EJ
- Wild S
- Witjes-Ane M-N
- Witjes-Ane M-N
- Wojcik M
- Wolz A
- Wolz M
- Wright J
- Yardumian P
- Zaremba J
- Zaremba J
- Zaugg SW
- Zdzienicka E
- Zema A
- Zielonka D
- Zielonka D
- Zinzi P
- Zucker B
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2009
- Field of study
Discrepancies in reporting the CAG repeat lengths for Huntington's disease.
- Author
- 't Hart EP
- Aaserud O
- Abbruzzese G
- Albanese A
- Alonso Frech F
- Andrews T
- Andrews T
- Andrich J
- Antczak J
- Arques PN
- Arran N
- Bachoud Lévi AC
- Badenes Guia D
- Banaszkiewicz K
- Bandettini di Poggio M
- Bandmann O
- Barbera MA
- Barker RA
- Barnes K
- Barrero F
- Barth K
- Bas J
- Bascuñana Garde M
- Bascuñana M
- Bauer P
- Bechtel N
- Beckmann H
- Beister A
- Bentivoglio AR
- Bentivoglio AR
- Bertini E
- Bisson J
- Biunno I
- Biunno I
- Bjørgo K
- Bjørnevoll I
- Boczarska Jedynak M
- Boelmans K
- Bohlen S
- Bolwijn JJ
- Bonelli R
- Bonelli RM
- Boogaerts A
- Bos R
- Bos R
- Bosca M
- Bourne C
- Bradbury A
- Braunwarth EM
- Brockie P
- Brugger F
- Bruno S
- Bryl A
- Buck A
- Buratti L
- Burguera JA
- Burgunder JM
- Burgunder JM
- Burgunder Y
- Burrows L
- Busquets N
- Busse M
- Bürk K
- Callaghan J
- Calopa M
- Cannella M
- Capellari S
- Catalli C
- Catena JL
- Causley A
- Cavaco S
- Chu C
- Chu E
- Ciesielska A
- Clapton J
- Clayton C
- Clenaghan C
- Codella V
- Coelho M
- Connemann J
- Constantinescu R
- Cormio C
- Correia Guedes L
- Cortelli P
- Craufurd D
- Crooks J
- Cubillo PT
- Cubillo PT
- Cubo E
- Curtis A
- Dalmau Elorza M
- Damásio J
- De Gregorio F
- De Michele G
- De Nicola N
- de Raedt S
- de Souza J
- DE TOMMASO Marina
- Dec M
- Dekker M
- Di Bella D
- Di Donato S
- Di Giacopo R
- Di Maio L
- Di Maria E
- Di Pietro A
- Difruscolo O
- Dipple H
- Doherty K
- Dose M
- Dougherty A
- Dumas EM
- Dumoulin C
- Dunnett SB
- Durán S
- Díez C
- Ecker D
- Ecker D
- Edwards M
- Ellison Rose L
- Eschenbach C
- Esmaeilzadeh M
- European Huntington’s Disease N.e.t.w.o.r.k. CollaboratorsBarth K
- Fairtlough H
- Fannemel M
- Fasano A
- Fatás Ventura M
- Fenollar M
- Ferrandes G
- Ferreira JJ
- Ferreira JJ
- Ferrer PQ
- Fillingham K
- Fisher K
- Flamez A
- Fletcher A
- Floriach Robert M
- Foster J
- Foustanos I
- Fredlund G
- Friedrich A
- Frontali M
- Fullam R
- Gago M
- Gallassi R
- Ganos C
- Garcia AC
- García de Yébenes J
- García R
- García R
- García Ribas G
- García Ruíz PJ
- Garrett C
- Garzón Ruíz B
- Gaston I
- Gelderblom H
- Gellera C
- Genitrini S
- Ghelli E
- Gill P
- Ginestroni A
- Golding C
- Golding C
- González Casado A
- Goodman A
- Gorospe A
- Grant J
- Gross D
- Guedes L
- Guerra MR
- Guidubaldi A
- Gørvell P
- Hallam C
- Hametner EM
- Hammer K
- Handley O
- Handley O
- Handley OJ
- Harding A
- Haro Martínez I
- Harrison D
- Harrower T
- Hasholt L
- Hecht K
- Heiberg A
- Heiberg A
- Heinicke W
- Held C
- Held C
- Henley S
- Hepperger C
- Hernanz LC
- Herranhof B
- Hidding U
- Hiivola H
- Hill S
- Hjermind LE
- Hobson E
- Hoffmann R
- Holas C
- Holl A
- Hotter A
- Howard L
- Howcroft D
- Hughes M
- Hughes T
- Hunger U
- Hunt S
- Huson S
- Hussl A
- Höglund A
- Hölzner E
- Høsterey Ugander U
- Ialongo T
- Illmann T
- Jachinska K
- Jack R
- Jacopini G
- Jakobsen O
- Jamieson S
- Jamrozik Z
- Janik P
- Jasinska Myga B
- Johns N
- José Saiz Artiga M
- Jurgens CK
- Kaelin A
- Kalbarczyk A
- Kapfhammer HP
- Kavalier F
- Kershaw A
- Kieni J
- Klempíř J
- Klimberg A
- Kline M
- Kodowska Duda G
- Koivisto SP
- Koivisto SP
- Koppers K
- Koppitz M
- Kosinski CM
- Kraus PH
- Krawczyk M
- Kremer B
- Krysa W
- Kucharík M
- Kwiecinski H
- Lahiri N
- Lambeck J
- Lambord N
- Landwehrmeyer B
- Landwehrmeyer GB
- Landwehrmeyer GB
- Lange H
- Lange H
- Lashwood A
- Laurà M
- Laver F
- Leenders KL
- Legarda I
- Levey J
- Lewerenz J
- Leythaeuser G
- Lezius F
- Lilek S
- Llesoy JR
- Longinus B
- Lorenza F
- Loria G
- López A
- López Sendón Moreno JL
- Löhle M
- Magalhães M
- Magnet M
- Mahlknecht P
- Mair K
- Mandich P
- Marchese R
- Marcinkowski J
- Maria Finisterra A
- Mariotti C
- Mariscal N
- Marit de Weert A
- Markova I
- Marquard R
- Martikainen K
- Martino T
- Martínez Descals A
- Martínez Descals A
- Mason S
- Massaro F
- Matheson K
- McGill M
- McKenzie S
- McLean T
- Mechi C
- Mendes T
- Mestre T
- Mestre T
- Middleton J
- Miedzybrodzka Z
- Milkereit E
- Miller J
- Minster S
- Modoni A
- Monza D
- Monza D
- Morales B
- Morez V
- Murch A
- Muth S
- Möller JC
- Müller N
- Münchau A
- Nanetti L
- Neleborn Lingefjärd L
- Nemeth AH
- Nepper S
- Nielsen JE
- Nielsen JE
- Niess A
- Nocker M
- Noguera Perea F
- Novak M
- Nørremølle A
- O'Donovan K
- Opala G
- Orth M
- Orth M
- Orth M
- Otti D
- Oughton E
- Overland T
- Padieu H
- Paganini M
- Painold A
- Paridi D
- Parkinson A
- Partington Jones L
- Patel A
- Paterski L
- Paterson N
- Patino D
- Patton M
- Paucar M
- Pearson P
- Peinemann A
- Peippo M
- Peppa N
- Peppa N
- Peterson M
- Piacentini S
- Piano C
- Piccininni C
- Poda R
- Poewe W
- Pons i. Càrdenas R
- Porteous M
- Pradella S
- Prehn C
- Price K
- Priller J
- Probst D
- Prüss H
- Päivärinta M
- Pålhagen SE
- Quaranta D
- Quarrell OW
- Quiroga PP
- Raab T
- Rabasa Perez M
- Rae D
- Rakowicz M
- Ramos Arroyo M
- Rankin J
- Raymond L
- Read J
- Reilmann R
- Reinante G
- Reisinger K
- Retterstøl L
- Rialland A
- Ribaï P
- Richter P
- Richter S
- Rickards H
- Rinaldi C
- Rissling I
- Ritchie S
- Rizzo G
- Robertson D
- Roca E
- Rohm S
- Rojo Sebastián A
- Rojo Sebastián A
- Romano S
- Romero I
- Romoli AM
- Roos RA
- Roos RA
- Rose S
- Rosser A
- Rosser E
- Roth J
- Rothery J
- Ruddy D
- Rudziñska M
- Ruiz Idiago JM
- Rumpf S
- Ruíz Vergara M
- Ryglewicz D
- Røren N
- Saft C
- Salmen S
- Salvatore E
- Samara H
- Sando SB
- Sandström B
- Sass C
- Say M
- Scaglione C
- Scheibl M
- Schepers S
- Schiefer J
- Schlangen C
- Schmalfeld J
- Schmidt S
- Schrenk C
- Schuierer M
- Schöggl H
- Schüpbach M
- Sciruicchio V
- Selimbegovic Turkovic A
- Sempoowicz J
- Seppi K
- Serpino C
- Silva M
- Simonelli M
- Simpson S
- Sipponen M
- Sitek E
- Slawek J
- Smith P
- Snowden J
- Soleti F
- Soliveri P
- Sollom A
- Soltan W
- Soltysiak B
- Sorbi S
- Soriano García S
- Spadaro M
- Spruth EJ
- Squitieri F
- Stamm C
- Stebler Y
- Steiner T
- Stokholm J
- Stokke B
- Stopford C
- Storch A
- Strassburger K
- Stubbe L
- Städtler M
- Suek A
- Suida G
- Summers F
- Svenningsson P
- Szczudlik A
- Sánchez J
- Sánchez V
- Sørensen SA
- Süssmuth S
- Tabrizi S
- Tabrizi SJ
- Taylor R
- Tedroff J
- Terol S
- Thomas G
- Thompson J
- Thomson A
- Thomson J
- Tidswell K.
- Tomasello C
- Tome Carruesco G
- Torres MM
- Torres Rodríguez MJ
- Toscano J
- Townhill J
- Townhill J
- Trautmann S
- Trender Gerhad I
- Tucci T
- Tuuha K
- Uhrova T
- Ullah J
- Uni M
- Ure A
- Valadas A
- Valeria Russo C
- van den Bogaard SJ
- van Hout MS
- van Oostrom JC
- van Reijen D
- van Vugt JP
- van Walsem MR
- van Walsem MR
- Vandenberghe W
- Vandenberghe W
- Verellen Dumoulin C
- Verstappen CC
- Verstraelen N
- Viladrich CM
- Villa Riballo A
- Villanueva C
- Vivancos Moreau L
- Vives B
- Vázquez Rivera S
- Wahlström J
- Wahlström J
- Walldén Reza Soltani T
- Warner T
- Wehus R
- Weindl A
- Wenning G
- Werner CJ
- Westmoreland L
- Weydt P
- Whaite A
- Wiedemann A
- Wild E
- Wild S
- Winnberg E
- Witjes Ané MN
- Witjes Ané MN
- Witkowski G
- Wolf E
- Wolz A
- Wolz M
- Wright J
- Wójcik M
- Yardumian P
- Yates S
- Yudina E
- Zangerl A
- Zaremba J
- Zaremba J
- Zaugg SW
- Zdzienicka E
- Zeman A
- Zielonka D
- Zielonka D
- Zielonka E
- Zinzi P
- Zinzi P
- Zittel S
- Zucker B
- Šašinková P
- Publication venue
- Publication date
- 01/01/2012
- Field of study
Huntington's disease results from a CAG repeat expansion within the Huntingtin gene; this is measured routinely in diagnostic laboratories. The European Huntington's Disease Network REGISTRY project centrally measures CAG repeat lengths on fresh samples; these were compared with the original results from 121 laboratories across 15 countries. We report on 1326 duplicate results; a discrepancy in reporting the upper allele occurred in 51% of cases, this reduced to 13.3% and 9.7% when we applied acceptable measurement errors proposed by the American College of Medical Genetics and the Draft European Best Practice Guidelines, respectively. Duplicate results were available for 1250 lower alleles; discrepancies occurred in 40% of cases. Clinically significant discrepancies occurred in 4.0% of cases with a potential unexplained misdiagnosis rate of 0.3%. There was considerable variation in the discrepancy rate among 10 of the countries participating in this study. Out of 1326 samples, 348 were re-analysed by an accredited diagnostic laboratory, based in Germany, with concordance rates of 93% and 94% for the upper and lower alleles, respectively. This became 100% if the acceptable measurement errors were applied. The central laboratory correctly reported allele sizes for six standard reference samples, blind to the known result. Our study differs from external quality assessment (EQA) schemes in that these are duplicate results obtained from a large sample of patients across the whole diagnostic range. We strongly recommend that laboratories state an error rate for their measurement on the report, participate in EQA schemes and use reference materials regularly to adjust their own internal standards
Discrepancies in reporting the CAG repeat lengths for Huntington's disease.
- Author
- 't Hart EP
- Aaserud O
- Abbruzzese G
- Albanese A
- Alonso Frech F
- Andrews T
- Andrews T
- Andrich J
- Antczak J
- Arques PN
- Arran N
- Bachoud Lévi AC
- Badenes Guia D
- Banaszkiewicz K
- Bandettini di Poggio M
- Bandmann O
- Barbera MA
- Barker RA
- Barnes K
- Barrero F
- Barth K
- Bas J
- Bascuñana Garde M
- Bascuñana M
- Bauer P
- Bechtel N
- Beckmann H
- Beister A
- Bentivoglio AR
- Bentivoglio AR
- Bertini E
- Bisson J
- Biunno I
- Biunno I
- Bjørgo K
- Bjørnevoll I
- Boczarska Jedynak M
- Boelmans K
- Bohlen S
- Bolwijn JJ
- Bonelli R
- Bonelli RM
- Boogaerts A
- Bos R
- Bos R
- Bosca M
- Bourne C
- Bradbury A
- Braunwarth EM
- Brockie P
- Brugger F
- Bruno S
- Bryl A
- Buck A
- Buratti L
- Burguera JA
- Burgunder JM
- Burgunder JM
- Burgunder Y
- Burrows L
- Busquets N
- Busse M
- Bürk K
- Callaghan J
- Calopa M
- Cannella M
- Capellari S
- Catalli C
- Catena JL
- Causley A
- Cavaco S
- Chu C
- Chu E
- Ciesielska A
- Clapton J
- Clayton C
- Clenaghan C
- Codella V
- Coelho M
- Connemann J
- Constantinescu R
- Cormio C
- Correia Guedes L
- Cortelli P
- Craufurd D
- Crooks J
- Cubillo PT
- Cubillo PT
- Cubo E
- Curtis A
- Dalmau Elorza M
- Damásio J
- De Gregorio F
- De Michele G
- De Nicola N
- de Raedt S
- de Souza J
- DE TOMMASO Marina
- Dec M
- Dekker M
- Di Bella D
- Di Donato S
- Di Giacopo R
- Di Maio L
- Di Maria E
- Di Pietro A
- Difruscolo O
- Dipple H
- Doherty K
- Dose M
- Dougherty A
- Dumas EM
- Dumoulin C
- Dunnett SB
- Durán S
- Díez C
- Ecker D
- Ecker D
- Edwards M
- Ellison Rose L
- Eschenbach C
- Esmaeilzadeh M
- European Huntington’s Disease N.e.t.w.o.r.k. CollaboratorsBarth K
- Fairtlough H
- Fannemel M
- Fasano A
- Fatás Ventura M
- Fenollar M
- Ferrandes G
- Ferreira JJ
- Ferreira JJ
- Ferrer PQ
- Fillingham K
- Fisher K
- Flamez A
- Fletcher A
- Floriach Robert M
- Foster J
- Foustanos I
- Fredlund G
- Friedrich A
- Frontali M
- Fullam R
- Gago M
- Gallassi R
- Ganos C
- Garcia AC
- García de Yébenes J
- García R
- García R
- García Ribas G
- García Ruíz PJ
- Garrett C
- Garzón Ruíz B
- Gaston I
- Gelderblom H
- Gellera C
- Genitrini S
- Ghelli E
- Gill P
- Ginestroni A
- Golding C
- Golding C
- González Casado A
- Goodman A
- Gorospe A
- Grant J
- Gross D
- Guedes L
- Guerra MR
- Guidubaldi A
- Gørvell P
- Hallam C
- Hametner EM
- Hammer K
- Handley O
- Handley O
- Handley OJ
- Harding A
- Haro Martínez I
- Harrison D
- Harrower T
- Hasholt L
- Hecht K
- Heiberg A
- Heiberg A
- Heinicke W
- Held C
- Held C
- Henley S
- Hepperger C
- Hernanz LC
- Herranhof B
- Hidding U
- Hiivola H
- Hill S
- Hjermind LE
- Hobson E
- Hoffmann R
- Holas C
- Holl A
- Hotter A
- Howard L
- Howcroft D
- Hughes M
- Hughes T
- Hunger U
- Hunt S
- Huson S
- Hussl A
- Höglund A
- Hölzner E
- Høsterey Ugander U
- Ialongo T
- Illmann T
- Jachinska K
- Jack R
- Jacopini G
- Jakobsen O
- Jamieson S
- Jamrozik Z
- Janik P
- Jasinska Myga B
- Johns N
- José Saiz Artiga M
- Jurgens CK
- Kaelin A
- Kalbarczyk A
- Kapfhammer HP
- Kavalier F
- Kershaw A
- Kieni J
- Klempíř J
- Klimberg A
- Kline M
- Kodowska Duda G
- Koivisto SP
- Koivisto SP
- Koppers K
- Koppitz M
- Kosinski CM
- Kraus PH
- Krawczyk M
- Kremer B
- Krysa W
- Kucharík M
- Kwiecinski H
- Lahiri N
- Lambeck J
- Lambord N
- Landwehrmeyer B
- Landwehrmeyer GB
- Landwehrmeyer GB
- Lange H
- Lange H
- Lashwood A
- Laurà M
- Laver F
- Leenders KL
- Legarda I
- Levey J
- Lewerenz J
- Leythaeuser G
- Lezius F
- Lilek S
- Llesoy JR
- Longinus B
- Lorenza F
- Loria G
- López A
- López Sendón Moreno JL
- Löhle M
- Magalhães M
- Magnet M
- Mahlknecht P
- Mair K
- Mandich P
- Marchese R
- Marcinkowski J
- Maria Finisterra A
- Mariotti C
- Mariscal N
- Marit de Weert A
- Markova I
- Marquard R
- Martikainen K
- Martino T
- Martínez Descals A
- Martínez Descals A
- Mason S
- Massaro F
- Matheson K
- McGill M
- McKenzie S
- McLean T
- Mechi C
- Mendes T
- Mestre T
- Mestre T
- Middleton J
- Miedzybrodzka Z
- Milkereit E
- Miller J
- Minster S
- Modoni A
- Monza D
- Monza D
- Morales B
- Morez V
- Murch A
- Muth S
- Möller JC
- Müller N
- Münchau A
- Nanetti L
- Neleborn Lingefjärd L
- Nemeth AH
- Nepper S
- Nielsen JE
- Nielsen JE
- Niess A
- Nocker M
- Noguera Perea F
- Novak M
- Nørremølle A
- O'Donovan K
- Opala G
- Orth M
- Orth M
- Orth M
- Otti D
- Oughton E
- Overland T
- Padieu H
- Paganini M
- Painold A
- Paridi D
- Parkinson A
- Partington Jones L
- Patel A
- Paterski L
- Paterson N
- Patino D
- Patton M
- Paucar M
- Pearson P
- Peinemann A
- Peippo M
- Peppa N
- Peppa N
- Peterson M
- Piacentini S
- Piano C
- Piccininni C
- Poda R
- Poewe W
- Pons i. Càrdenas R
- Porteous M
- Pradella S
- Prehn C
- Price K
- Priller J
- Probst D
- Prüss H
- Päivärinta M
- Pålhagen SE
- Quaranta D
- Quarrell OW
- Quiroga PP
- Raab T
- Rabasa Perez M
- Rae D
- Rakowicz M
- Ramos Arroyo M
- Rankin J
- Raymond L
- Read J
- Reilmann R
- Reinante G
- Reisinger K
- Retterstøl L
- Rialland A
- Ribaï P
- Richter P
- Richter S
- Rickards H
- Rinaldi C
- Rissling I
- Ritchie S
- Rizzo G
- Robertson D
- Roca E
- Rohm S
- Rojo Sebastián A
- Rojo Sebastián A
- Romano S
- Romero I
- Romoli AM
- Roos RA
- Roos RA
- Rose S
- Rosser A
- Rosser E
- Roth J
- Rothery J
- Ruddy D
- Rudziñska M
- Ruiz Idiago JM
- Rumpf S
- Ruíz Vergara M
- Ryglewicz D
- Røren N
- Saft C
- Salmen S
- Salvatore E
- Samara H
- Sando SB
- Sandström B
- Sass C
- Say M
- Scaglione C
- Scheibl M
- Schepers S
- Schiefer J
- Schlangen C
- Schmalfeld J
- Schmidt S
- Schrenk C
- Schuierer M
- Schöggl H
- Schüpbach M
- Sciruicchio V
- Selimbegovic Turkovic A
- Sempoowicz J
- Seppi K
- Serpino C
- Silva M
- Simonelli M
- Simpson S
- Sipponen M
- Sitek E
- Slawek J
- Smith P
- Snowden J
- Soleti F
- Soliveri P
- Sollom A
- Soltan W
- Soltysiak B
- Sorbi S
- Soriano García S
- Spadaro M
- Spruth EJ
- Squitieri F
- Stamm C
- Stebler Y
- Steiner T
- Stokholm J
- Stokke B
- Stopford C
- Storch A
- Strassburger K
- Stubbe L
- Städtler M
- Suek A
- Suida G
- Summers F
- Svenningsson P
- Szczudlik A
- Sánchez J
- Sánchez V
- Sørensen SA
- Süssmuth S
- Tabrizi S
- Tabrizi SJ
- Taylor R
- Tedroff J
- Terol S
- Thomas G
- Thompson J
- Thomson A
- Thomson J
- Tidswell K.
- Tomasello C
- Tome Carruesco G
- Torres MM
- Torres Rodríguez MJ
- Toscano J
- Townhill J
- Townhill J
- Trautmann S
- Trender Gerhad I
- Tucci T
- Tuuha K
- Uhrova T
- Ullah J
- Uni M
- Ure A
- Valadas A
- Valeria Russo C
- van den Bogaard SJ
- van Hout MS
- van Oostrom JC
- van Reijen D
- van Vugt JP
- van Walsem MR
- van Walsem MR
- Vandenberghe W
- Vandenberghe W
- Verellen Dumoulin C
- Verstappen CC
- Verstraelen N
- Viladrich CM
- Villa Riballo A
- Villanueva C
- Vivancos Moreau L
- Vives B
- Vázquez Rivera S
- Wahlström J
- Wahlström J
- Walldén Reza Soltani T
- Warner T
- Wehus R
- Weindl A
- Wenning G
- Werner CJ
- Westmoreland L
- Weydt P
- Whaite A
- Wiedemann A
- Wild E
- Wild S
- Winnberg E
- Witjes Ané MN
- Witjes Ané MN
- Witkowski G
- Wolf E
- Wolz A
- Wolz M
- Wright J
- Wójcik M
- Yardumian P
- Yates S
- Yudina E
- Zangerl A
- Zaremba J
- Zaremba J
- Zaugg SW
- Zdzienicka E
- Zeman A
- Zielonka D
- Zielonka D
- Zielonka E
- Zinzi P
- Zinzi P
- Zittel S
- Zucker B
- Šašinková P
- Publication venue
- Publication date
- 01/01/2012
- Field of study
Huntington's disease results from a CAG repeat expansion within the Huntingtin gene; this is measured routinely in diagnostic laboratories. The European Huntington's Disease Network REGISTRY project centrally measures CAG repeat lengths on fresh samples; these were compared with the original results from 121 laboratories across 15 countries. We report on 1326 duplicate results; a discrepancy in reporting the upper allele occurred in 51% of cases, this reduced to 13.3% and 9.7% when we applied acceptable measurement errors proposed by the American College of Medical Genetics and the Draft European Best Practice Guidelines, respectively. Duplicate results were available for 1250 lower alleles; discrepancies occurred in 40% of cases. Clinically significant discrepancies occurred in 4.0% of cases with a potential unexplained misdiagnosis rate of 0.3%. There was considerable variation in the discrepancy rate among 10 of the countries participating in this study. Out of 1326 samples, 348 were re-analysed by an accredited diagnostic laboratory, based in Germany, with concordance rates of 93% and 94% for the upper and lower alleles, respectively. This became 100% if the acceptable measurement errors were applied. The central laboratory correctly reported allele sizes for six standard reference samples, blind to the known result. Our study differs from external quality assessment (EQA) schemes in that these are duplicate results obtained from a large sample of patients across the whole diagnostic range. We strongly recommend that laboratories state an error rate for their measurement on the report, participate in EQA schemes and use reference materials regularly to adjust their own internal standards
Optimization of adsorptive removal of α-toluic acid by CaO2 nanoparticles using response surface methodology
- Author
- 't Hart Ellen P.
- Aaserud Olaf
- Abbruzzese Giovanni
- Aguilar Barbera Miquel
- Albanese Alberto
- Allain Philippe
- Alonso-Frech Fernando
- Andrews Thomasin
- Andrews Thomasin
- Andrich Jürgen
- Antczak Jakub
- Antequera Torres María Martirio
- Arran Natalie
- Azulay Jean-Philippe
- Babiloni Blandine
- Bachoud-Lévi A. C.
- Badenes Guia Dolors
- Banaszkiewicz Krzysztof
- Bandettini di Poggio Monica
- Bandmann Oliver
- Barker Roger A.
- Barnes Kathy
- Barrero Francisco
- Barth Katrin
- Barth Katrin
- Bas Jordi
- Bascuñana Garde Mónica
- Bascuñana Garde Mónica
- Bastida Antonio Martín
- Bate Louise
- Bechtel Natalie
- Beckmann Heike
- Beister Antonie
- Bellonet Marcellin
- Bentivoglio A. R.
- Bentivoglio Anna Rita
- Bertini Elisabetta
- Bisson Jonathan
- Biunno I.
- Björn Yvonne
- Bjørgo Kathrine
- Bjørnevoll Inga
- Blinkenberg Ellen Økland
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen Stefan
- Bolwijn J. J. W.
- Bonelli Raphael M.
- Bonelli Raphael M.
- Bonelli Raphael M.
- Boogaerts Andrea
- Borgerød Nancy
- Bos Reineke
- Bos Reineke
- Bosca Maria
- Bourne Colin
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brockie Peter
- Brugger Florian
- Bruno Stefania
- Bryl Anna
- Buck Andrea
- Buongiorno Maria Teresa
- Buratti Lisa
- Burg Sabrina
- Burguera Juan Andrés
- Burgunder J. M.
- Burgunder Jean-Marc
- Burgunder Yvonne
- Burn John
- Burns Peter
- Burrows Liz
- Busquets Núria
- Busse Monica
- Bürk Kathrin
- Callaghan Jenny
- Calopa Matilde
- Calvas Fabienne
- Campos Garcia Anabel
- Cannella Milena
- Capellari Sabrina
- Carette Anne-Sophie
- Carrillo Fátima
- Casas Hernanz Laura
- Catalli Claudio
- Causley Aaron
- Cavaco Sara
- Chabot Christelle
- Chacón Peña José
- Cheriet Samia
- Chu Carol
- Chu Carol
- Chu Elvina
- Ciesielska Anna
- Clapton Jackie
- Clayton Carole
- Clenaghan Catherine
- Codella Valentina
- Coelho Miguel
- Coleman Caroline
- Connemann Julia
- Constantinescu Radu
- Cormio Claudia
- Correia Guedes Leonor
- Correia Guedes Leonor
- Cortelli Pietro
- Costa Cristina
- Craufurd David
- Crooks Jenny
- Cubo Esther
- Curtis Adrienne
- Cáceres María Teresa
- Dalmau Elorza Marina
- Damásio Joana
- de Bruycker Christelle
- de Gregorio Francesca
- de Michele Giuseppe
- de Nicola Nunzia
- de Raedt Sylvie
- de Souza Jenny
- de Tommaso Marina
- de Weert A. Marit
- Debruxelles Sabrina
- Dec Malgorzata
- Decorte Eric
- Dekker M.
- Delliaux Marie
- Delphini Marie
- Delval Arnaud
- di Bella Daniela
- di Donato Stefano
- di Giacopo Raffaella
- di Maio Luigi
- di Maria Emilio
- di Pietro Anna
- Diercks Gabriele
- Difruscolo Olimpia
- Dinca Avarvarei Luminita
- Dipple Heather
- Doherty Karen
- Dose Matthias
- Dougherty Andrew
- Dujardin Kathy
- Dumas Eve M.
- Dunnett S. B.
- Dunnett Stephen B.
- Duru Cécile
- Durán Herrera Carmen
- Durán-Sindreu Terol Santiago
- Démonet Jean-Francois
- Díez-Aja López Cristóbal
- Ecker Daniel
- Ecker Daniel
- Edwards Maureen
- Ekwall Camilla
- Ellison-Rose Lynda
- Eschenbach Carolin
- Esmaeilzadeh Mona
- European Huntington's Disease Network
- Eusebio Alexandre
- Evans Carole
- Fairtlough Helen
- Fannemel Madelein
- Fasano Alfonso
- Fatás Ventura Marta
- Fenollar María
- Fernández Recio Maria
- Ferrandes Giovanna
- Ferreira J. J.
- Ferreira Joaquim J.
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flamez Anja
- Fletcher Amy
- Floriach Robert Misericordia
- Foster Jillian
- Foustanos Isabella
- Fredlund Gunnel
- Frich Jan
- Friedrich Andrea
- Frontali Marina
- Fullam Ruth
- Gago Miguel
- Galitzky Monique
- Gallassi Roberto
- Ganos Christos
- Garcia Moreno José Manuel
- García de Yébenes Justo
- García Ribas Guillermo
- García Ruíz Pedro J.
- García-Ramos García Rocío
- Garrett Carolina
- Garzón Ruíz Belén
- Gaston Itziar
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Ghelli Elena
- Gill Paul
- Ginestroni Andrea
- Giuliano J.
- Gohier Bénédicte
- Goizet Cyril
- Golding Charlotte
- Golding Charlotte
- González Casado Ana
- González González Sonia
- Goodman Anna
- Gorospe Aranzazú
- Gorzolla Heike
- Grant Janet
- Grosjean Hélène
- Gross Diana
- Guerra Maria Rosália
- Guidubaldi Arianna
- Guérid Marie-Anne
- Gøller Marie-Louise
- Gørvell Per
- Hallam Caroline
- Hamer Stephanie
- Hametner Eva-Maria
- Hammer Kathrin
- Handley Olivia J.
- Handley Olivia J.
- Handley Olivia J.
- Handley Olivia J.
- Harding Alison
- Haro Martínez Isabel
- Harrison David
- Harrower Timothy
- Hasholt Lis
- Hauge Erik
- Hayward Beverley
- Hecht Karen
- Heiberg Arvid
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Held Christine
- Henley Susie
- Hepperger Caroline
- Herranhof Brigitte
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Hjermind Lena E.
- Hobson Emma
- Hoffmann Rainer
- Holas Christiane
- Holl Anna
- Hotter Anna
- Howard Liz
- Howcroft Debbie
- Hughes Max
- Hughes Teresa
- Hunger Ulrike
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Höglund Arja
- Hölzner Eva
- Høsterey-Ugander Ulrika
- Ialongo Tamara
- Ignatius Jaakko
- Illmann T.
- Illmann T.
- Jachinska Katarzyna
- Jack Roisin
- Jacopini Gioia
- Jakobsen Oda
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Januário Cristina
- Jasinska-Myga Barbara
- Johansson Anders
- Johns Nicola
- Jurgens Caroline K.
- Júlio Filipa
- Kaelin Alain
- Kalbarczyk Anna
- Kapfhammer Hans-Peter
- Kavalier Fred
- Kershaw Ann
- Kieni Janina
- Klempí Jirí
- Klimberg Aneta
- Klodowska-Duda Gabriela
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kraus Peter H.
- Krawczyk Malgorzata
- Kremer Berry
- Krysa Wioletta
- Krystkowiak Pierre
- Kucharík Martin
- Kwiecinski Hubert
- Kärppä Mikko
- Ladurner Gunther
- Lafoucrière Danielle
- Lahiri Nayana
- Lama Suarez María José
- Lambeck Johann
- Lambord Nicol
- Landwehrmeyer Bernhard Georg
- Landwehrmeyer G. Bernhard
- Landwehrmeyer G. Bernhard
- Lange Herwig
- Lange Herwig
- Lashwood Alison
- Laurà Mathilde
- Laver Fiona
- Leenders K. L.
- Legarda Inés
- Levey J.
- Lewerenz Jan
- Leythaeuser Gabriele
- Lezius Franziska
- Lilek Sabine
- Lilek Stefan
- Longinus Bernhard
- Lorenza Fortuna
- Loria Giovanna
- Loutfi Ghada
- López Catena Judit
- López del Val Javier
- López-Sendón Moreno José Luis
- Löhle Matthias
- Magalhães Marina
- Magnet Markus
- Mahlknecht Philipp
- Mair Katharina
- Majeed Tahir
- Mandich Paola
- Marchese Roberta
- Marcinkowski Jerzy T.
- Mareca Viladrich Celia
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Markova Ivana
- Marquard Ralf
- Martikainen Kirsti
- Martino Tiziana
- Martínez Martinez Laura
- Martínez-Descals Asunción
- Martínez-Descals Asunción
- Mason Sarah
- Massaro Francesca
- Matheson Kirsty
- McGill Marie
- McKenzie Sue
- McLean Tim
- Mechi Claudia
- Mendes Tiago
- Menéndez Guisasola Luis
- Mestre Tiago
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Milkereit Eva
- Miller Joanne
- Miller Julie
- Minster Sara
- Mir Pablo
- Modoni Anna
- Monza Daniela
- Monza Daniela
- Morales Blas
- Moreno Garcia Patrocinio
- Morez V.
- Mundler Laura
- Murch Ann
- Muth Sabine
- Muñoz Esteban
- Möller Jens Carsten
- Müller Nicole
- Münchau Alexander
- Nanetti Lorenzo
- Navas Arques Penelope
- Neleborn-Lingefjärd Liselotte
- Nemeth Andrea H.
- Nepper Solveig
- Nielsen J. E.
- Nielsen Jørgen
- Niess Anke
- Nocker Michael
- Noguera Perea María Fuensanta
- Novak Marianne
- Nowak Marielle
- Nørremølle Anne
- O'Donovan Kirsty
- Olivier Audrey
- Olofsson Carina
- Opala Gregorz
- Orth Michael
- Orth Michael
- Orth Michael
- Orth Michael
- Orth Michael
- Otti Daniela
- Oughton Emma
- Overland Torborg
- Padieu Helene
- Paganini Marco
- Painold Annamaria
- Paridi Dominga
- Parkinson Andrew
- Partington-Jones Lucy
- Pate Louise
- Patel Aakta
- Paterski Laurent
- Paterson Nicole
- Patino Dawn
- Patton Michael
- Paucar Martin
- Pearson Pauline
- Peinemann Alexander
- Peippo Maarit
- Peppa Nadia
- Peppa Nadia
- Peter Mireille
- Petersen Asa
- Peterson Maria
- Piacentini Silvia
- Piano Carla
- Piccininni Chiara
- Pin Quiroga Purificacion
- Plomhouse Lucie
- Poda Roberto
- Poewe Werner
- Pons i Càrdenas Regina
- Porteous Mary
- Pradella Silvia
- Prehn Christian
- Price Kathleen
- Priller Josef
- Pro Koivisto Susana
- Pro Koivisto Susana
- Probst Daniela
- Prundean Adriana
- Prüss Harald
- Päivärinta M.
- Pålhagen Sven E.
- Quaranta Davide
- Quarrell Oliver
- Quiléz Ferrer Pilar
- Raab Tina
- Rabasa Perez Maria
- Rae Daniela
- Rakowicz Maria
- Raman Ashok
- Ramos-Arroyo Maria A.
- Rankin Julia
- Raymond Lucy
- Read Joy
- Redondo Vergé Luis
- Reilmann Ralf
- Reimer Jan
- Reinante Gema
- Reisinger Karin
- Retterstøl Lars
- Reza-Soltani Tina Walldén
- Rialland Amandine
- Ribaï Pascale
- Ribbat Michael
- Richter Przemyslaw
- Richter Sven
- Rickards Hugh
- Rinaldi Carlo
- Rissling Ida
- Ritchie Stuart
- Rizzo Giovanni
- Robertson Dene
- Roca Elvira
- Rohm Stefanie
- Roig Llesoy Joan
- Rojo Sebastián Ana
- Romano Silvia
- Romero Irene
- Romoli Anna Maria
- Roos R. A.
- Roos Raymund A.
- Rose Sarah
- Rosser Anne
- Rosser Elisabeth
- Roth Jan
- Rothery Jean
- Roussel Martine
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzinska Monika
- Rumpf Silke
- Russo Cinzia Valeria
- Ruíz Idiago Jesús Miguel
- Ruíz Vergara Mar
- Ryglewicz Danuta
- Røren Ninni
- Saft Carsten
- Saiz Artiga María José
- Salmen Stephan
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- Sanchez Jesús
- Sando Sigrid Botne
- Sandström Britta
- Santala Maire
- Sasinková Pavla
- Sass Christian
- Say Miranda
- Scaglione Cesa
- Scheibl Monika
- Schepers Sigrun
- Scherer-Gagou Clarisse* Gagou, Clarisse Scherer-
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schrader Christoph
- Schrenk Caroline
- Schuierer Michele
- Schwenke C.
- Schwenke Carsten
- Schöggl Helmut
- Schüpbach Michael
- Sciruicchio Vittorio
- Sebastián A. R.
- Selimbegovic-Turkovic Amina
- Sempolowicz Justyna
- Senkárová Zuzana
- Seppi Klaus
- Serpino Claudia
- Sieradzan Kasia
- Silva Mark
- Simonelli Maria
- Simonin Clémence
- Simpson Sheila
- Sinadinosa Daniela
- Sipponen Marjatta
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Smith Paul
- Snowden Julie
- Soleti Francesco
- Solis Pilar
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltani Riza
- Soltysiak Beverley
- Sorbi Sandro
- Soriano García Socorro
- Spadaro Maria
- Spruth Eike Jakob
- Squitieri Ferdinando
- Staffen Wolfgang
- Stamm Christiane
- Stattin Eva-Lena
- Stebler Yanik
- Steiner Tanja
- Steinmetz Gisèle
- Stokholm Jette
- Stokke Bodil
- Stopford Cheryl
- Storch Alexander
- Strassburger Katrin
- Stubbe Lars
- Städtler Michael
- Suaréz San Martín Esther
- Sulek Anna
- Summers Fiona
- Svenningsson Per
- Szczudlik Andrzej
- Sánchez Sánchez Violeta
- Sánchez Vicenta
- Sørensen Sven Asger
- Süßmuth Sigurd
- Tabrizi S. J.
- Tabrizi Sarah
- Tabrizi Sarah
- Taylor Rachel
- Tedroff Joakim
- Thibault-Tanchou Stéphanie
- Thomas Gareth
- Thompson Jennifer
- Thomson Aileen
- Thomson Jenny
- Tidswell Katherine
- Timóteo Angela
- Tomasello Chiara
- Tome Carruesco Gemma
- Torres Rodríguez María José
- Toscano Jean
- Townhill Jenny
- Townhill Jenny
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhad Iris
- Trigo Cubillo Patricia
- Trigo Cubillo Patricia
- Tritsch Christine
- Tucci Tecla
- Tuuha Katri
- Tyvoll Hilde
- Uhrova T.
- Ullah Jasmin
- Ure Alexandra
- Valadas Anabela
- Vale José
- van den Bogaard Simon J. A.
- van Hout Monique S.
- van Kammen D.
- van Oostrom J. C. H.
- van Reijen Dimphna
- van Vugt Jeroen P.
- van Walsem Marleen R.
- van Walsem Marlene R.
- Vandenberghe Wim
- Vandenberghe Wim
- Verellen-Dumoulin Christine
- Verellen-Dumoulin Christine
- Verny Christophe
- Verstappen C. C. P.
- Verstraelen Nichola
- Verstraelen Nichola
- Villa Riballo Antonio
- Villanueva Clara
- Vivancos Moreau Laura
- Vives Barbara
- Vázquez Rivera Susana
- Wagner Caroline
- Wahlström J.
- Wahlström Jan
- Walleczek Anna Maria
- Wallner M.
- Wannepain Sandrine
- Warner Thomas
- Weber Zaugg Sabine
- Wehus Raghild
- Weindl Adolf
- Wenning Gregor
- Werner Cornelius Johannes
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Widner Hakan
- Wiedemann Alexandra
- Wiklund Leif
- Wikström Birgitta
- Wild E. J.
- Wild Edward
- Wild Sue
- Winnberg Elisabeth
- Witjes-Ané Marie-Noelle
- Witjes-Ané Marie-Noelle
- Witkowski Grzegorz
- Wolf Elisabeth
- Wolz Annett
- Wolz Martin
- Wright Abigail
- Wright Jan
- Wójcik Magdalena
- Yardumian Pam
- Yates Shona
- Yudina Elizaveta
- Zangerl Anja
- Zaremba J.
- Zaremba Jacek
- Zdzienicka Elzbieta
- Zeman Adam
- Zielonka Daniel
- Zielonka Daniel
- Zielonka Eugeniusz
- Zimmermann Marie-Agathe
- Zinzi Paola
- Zinzi Paola
- Zittel Simone
- Zucker Birgit
- Åman Jaana
- Publication venue
- Elsevier
- Publication date
- 01/01/2011
- Field of study
The present work addresses the optimization of process parameters for adsorptive removal of α-toluic acid by calcium peroxide (CaO2) nanoparticles using response surface methodology (RSM). CaO2 nanoparticles were synthesized by chemical precipitation method and confirmed by Transmission electron microscopy (TEM) and high-resolution TEM (HRTEM) analysis which shows the CaO2 nanoparticles size range of 5–15 nm. A series of batch adsorption experiments were performed using CaO2 nanoparticles to remove α-toluic acid from the aqueous solution. Further, an experimental based central composite design (CCD) was developed to study the interactive effect of CaO2 adsorbent dosage, initial concentration of α-toluic acid, and contact time on α-toluic acid removal efficiency (response) and optimization of the process. Analysis of variance (ANOVA) was performed to determine the significance of the individual and the interactive effects of variables on the response. The model predicted response showed a good agreement with the experimental response, and the coefficient of determination, (R2) was 0.92. Among the variables, the interactive effect of adsorbent dosage and the initial α-toluic acid concentration was found to have more influence on the response than the contact time. Numerical optimization of process by RSM showed the optimal adsorbent dosage, initial concentration of α-toluic acid, and contact time as 0.03 g, 7.06 g/L, and 34 min respectively. The predicted removal efficiency was 99.50%. The experiments performed under these conditions showed α-toluic acid removal efficiency up to 98.05%, which confirmed the adequacy of the model prediction
Suicidal ideation in a European Huntington's disease population.
- Author
- 't Hart Ellen P
- Aaserud Olaf
- Abbruzzese Giovanni
- Akhtar Shahbana
- Albanese Alberto
- Alberti Silvia
- Alegre Javier
- Allain Philippe
- Alonso-Frech Fernando
- Amico Enrico
- Ammendola Sarah
- Andrade Carlos
- Andrews Thomasin
- Andrich Jürgen
- Antczak Jakub
- Armstrong Richard
- Arques Penelope Navas
- Arran Natalie
- Artiga María José Saiz
- Avarvarei Luminita Dinca
- Azulay Jean-Philippe
- Babiloni Blandine
- Bachoud-Lévi A-C
- Banaszkiewicz Krzysztof
- Bandmann Oliver
- Barbera Miquel Aguilar
- Barker Roger A
- Barrero Francisco
- Barth Katrin
- Bas Jordi
- Bascuñana Mónica
- Bastida Antonio Martín
- Bek Judith
- Bellonet Marcellin
- Bentivoglio A R
- Bentivoglio Anna Rita
- Bernhard Landwehrmeyer G
- Berrissoul Hassan
- Bertini Elisabetta
- Betz Sabrina
- Bisson Jonathan
- Biunno I
- Bjørgo Kathrine
- Blaszcyk Magdalena
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen Stefan
- Bolwijn J J W
- Bonelli R M
- Bonelli Raphael M
- Boogaerts Andrea
- Bos Reineke
- Bosca Maria
- Bosredon Cecile
- Bost Marie
- Boćwińska Dorota
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brockie Peter
- Brugada Francisco Casterá
- Brugger Florian
- Bruno Stefania
- Bryl Anna
- Buck Andrea
- Buratti Lisa
- Burguera Juan Andres
- Burgunder J-M
- Burgunder Jean-Marc
- Burn John
- Burrows Liz
- Busquets Núria
- Busse Monica
- Butcher Cynthia
- Bárcenas Antonio Herranz
- Bürk Kathrin
- Cabaret Maryline
- Caldentey Juan Garcia
- Callaghan Jenny
- Calopa Matilde
- Calvas Fabienne
- Capellari Sabina
- Capetian Philipp
- Carette Anne-Sophie
- Carrillo Fátima
- Carruesco Gemma Tome
- Casado Ana González
- Catalli Claudio
- Catena Judit López
- Cavaco Sara
- Cheriet Samia
- Chiara Piccininni
- Chu Carol
- Chu Elvina
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Clayton Carole
- Clenaghan Catherine
- Coelho Miguel
- Coleman Caroline
- Connemann Julia
- Constantinescu Radu
- Cormio Claudia
- Correia-Guedes Leonor
- Cortelli Pietro
- Costa Cristina
- Courtin Françoise
- Craufurd David
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- Càrdenas Regina Ponsi
- Cáceres María Teresa
- da Silva Wildson Vieira
- Damásio Joana
- Davidson Jill
- De Bruycker Christelle
- De Michele Giuseppe
- de Raedt Sylvie
- Debruxelles Sabrina
- Dec Małgorzata
- Decorte Eric
- Defebvre Luc
- Dekker M
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Descals Asunción Martínez
- Destee Alain
- Di Bella Daniela
- Di Donato Stefano
- Di Giacopo Raffaella
- Di Maio Luigi
- Di Maria Emilio
- Di Pardo Alba
- Di Pietro Anna
- di Poggio Monica Bandettini
- Diercks Gabriele
- Dipple Heather
- Doherty Karen
- Dose Matthias
- Dougherty Andrew
- Downie Lorna
- Dressler Dirk
- Duché Charlotte
- Dujardin Kathy
- Dumas Eve M
- Dunnett S B
- Dunnett Stephen
- Duru Cécile
- Dziadkiewicz Artur
- Démonet Jean-François
- Díez-AjaLópez Cristóbal
- Ecker Daniel
- Edwards Maureen
- Ekwall Camilla
- Elifani Francesca
- Ellrichmann Gisa
- Elorza Marina Dalmau
- Eschenbach Carolin
- Esmaeilzadeh Mona
- Eusebio Alexandre
- Fairtlough Helen
- Fannemel Madeleine
- Fasano Alfonso
- Fasquel Véronique
- Fenollar María
- Ferrandes Giovanna
- Ferreira J J
- Ferreira Joaquim J
- Ferrer Pilar Quiléz
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flamez Anja
- Fletcher Amy
- Fluchère Frédér- ique
- Fortuna Lorenza
- Foster Jillian
- Foustanos Isabella
- Fredlund Gunnel
- Freire-Patino Dawn
- Frich Jan
- Frontali Marina
- Fullam Ruth
- Gago Miguel
- Gallantrae Deena
- Gallassi Roberto
- Ganos Christos
- Garcia Anabel Campos
- Garcia Patrocinio Moreno
- García Ruíz Pedro J
- García Rocío García-Ramos
- García Socorro Soriano
- Garde Monica Bascuñana
- Garrett Carolina
- Gaston Itziar
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Ghelli Elena
- Gill Paul
- Giltay Erik J
- Ginestroni Andrea
- Godefroy Olivier
- Goerendt Ines
- Gogol Anna
- Gohier Bénédicte
- Goizet Cyril
- Golding Charlotte
- González Mónica
- González Sonia González
- Gorospe Aranzazú
- Gorzkowska Agnieszka
- Gorzolla Heike
- Griguoli Annamaria
- Guerra Maria Rosália
- Guerrero Rosa
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guisasola Luis Menéndez
- Guzman [Unknown]
- Guérid Marie-Anne
- Göller Marie-Louise
- Gørvell Per
- Haider Salman
- Hamer Stephanie
- Hametner Eva-Maria
- Handley O J
- Handley Olivia
- Harding Alison
- Hare Marianne
- Harrison David
- Hartikainen Päivi
- Hauge Erik
- Hayward Beverley
- Hecht Karen
- Heiberg A
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Hensman Davina
- Hepperger Caroline
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Durán
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Ho Carrie
- Hobson Emma
- Hoffmann Rainer
- Holas Christiane
- Holl Anna
- Horta Saul Martinez
- Hotter Anna
- Howard Liz
- Hubers Anna A M
- Hughes Alis
- Hughes Max
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Hvalstedt Carina
- Höglund Arja
- Hölzner Eva
- Høsterey-Ugander Ulrika
- Ialongo Tamara
- Idiago Jesús Miguel Ruiz
- ielewska Anna Was
- Ignatius Jaakko
- Jachinska Katarzyna
- Jack Roisin
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Januário Cristina
- Jaremek Kamila Bojakowska
- Jasinska-Myga Barbara
- Johansson Anders
- Johns Nicola
- Johnson Liz
- Johnstone Catherine
- Jones Lesley
- Jones Mary
- Jones Una
- Júlio Filipa
- Kaelin Alain
- Kajula Outi
- Kaminska Anna
- Kaminski Barbara
- Kapfhammer Hans-Peter
- Kavalier Fred
- Kazoka Mbombe
- Khalil Hanan
- Klempíř Jiří
- Klimberg Aneta
- Kohl Zacharias
- Koivisto Susana Pro
- Komati Suresh
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kraus Alison
- Krawczyk Malgorzata
- Kremer H P H
- Krysa Wioletta
- Krystkowiak Pierre
- Kwiecinski Hubert
- Kärppä Mikko
- Kłodowska-Duda Gabriela
- Ladurner Gunther
- Lafoucrière Danielle
- Lahiri Nayana
- Laing Hana
- Lambeck Johann
- Landwehrmeyer Bernhard
- Landwehrmeyer G B
- Lange Herwig
- Lashwood Alison
- Laurà Matilde
- Laver Fiona
- Leenders K L
- Legarda Inés
- Lemaire Marie-Hélène
- Levey J
- Lewerenz Jan
- Lewis Monica
- Leythaeuser Gabriele
- Lezius Franziska
- lhagen Sven E P
- Lilek Sabine
- Lilek Stefan
- Lima Joana
- Llesoy Joan Roig
- llmann T I
- Longato Nadine
- Longinus Bernhard
- Longthorpe Mandy
- Lorentzen Eirin
- Loria Giovanna
- Loureiro Rui
- Loutfi Ghada
- López-Sendón Moreno José Luis
- Maass Antonia
- Magalhães Marina
- Maglione Vittorio
- Magnet Markus
- Majerová Veronika
- Mandich Paola
- Manouvrier Sylvie
- Mantaux Béatrice
- Manuel Jose
- Marcel Christophe
- Marchese Roberta
- Marcinkowski Jerzy
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Marquard Ralf
- Martikainen Kirsti
- Martinez-Jaurrieta Maria Dolores
- Martino Tiziana
- Martirio María
- Martínez Isabel Haro
- Martínez Laura Martinez
- Martínez-Descals Asunción
- Mason Sarah
- Massano João
- Massarelli Marco
- Massaro Francesca
- Matheson Kirsty
- McGill Marie
- McKenzie Sue
- Mechi Claudia
- Meireles Joana
- Mendes Tiago
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Milkereit Eva
- Miller Joanne
- Minster Sara
- Mir Pablo
- Monza Daniela
- Morales Blas
- Moreau Laura Vivancos
- Moreno Garcia
- Morez V
- Morgan Karen
- Mundler Laura
- Murphy Helen
- Musgrave Hannah
- Mustonen Aki
- Möller Jens Carsten
- Mühlau Mark
- Müller Christoph
- Müller Nicole
- Münchau Alexander
- Mütze Lisanne
- Nanetti Lorenzo
- Neleborn-Lingefjärd Liselotte
- Nemeth Andrea H
- Nepper Solveig
- Nielsen J E
- Nielsen Mette Gilling
- Niess Anke
- Noguera Perea María Fuensanta
- Novak Marianne
- Nowak Malgorzata
- O'Donovan Kirsty
- O'Keefe Deidre
- Oehmen Martin
- Olivier Audrey
- Olofsson Carina
- Opala Gregorz
- Orth Michael
- Otti Daniela
- Oughton Emma
- Overland Torborg
- Owen Michael
- Padieu Helene
- Paganini Marco
- Painold Annamaria
- Paridi Dominga
- Pariente Jérémie
- Parkinson Andrew
- Partington-Jones Lucy
- Patel Aakta
- Paterski Laurent
- Patton Michael
- Paucar Martin
- Pearson Pauline
- Peinemann Alexander
- Peppa Nadia
- Perez Maria Rabasa
- Peter Mireille
- Peterson Maria
- Petersén Asa
- Petrollini Martina
- Peña José Chacón
- Piacentini Silvia
- Piano Carla
- Plomhouse Lucie
- Poda Roberto
- Poewe Werner
- Porteous Mary
- Pradella Silvia
- Price Kathleen
- Priller Josef
- Probst Daniela
- ProKoivisto S
- Prundean Adriana
- Prüß Harald
- Päivärinta M
- Pålhagen Sven
- Quaranta Davide
- Quarrell Oliver
- Quiroga Purificacion Pin
- Raab Tina
- Rae Daniela
- Rakowicz Maryla
- Raman Ashok
- Ramos-Arroyo Maria A
- Recio Maria Fernández
- Reetz Kathrin
- Reilmann Ralf
- Reimer Jan
- Reinante Gema
- Reisinger Karin
- Retterstøl Lars
- Reza- Soltani Tina Walldén
- Rialland Amandine
- Riballo Antonio Villa
- Ribas Guillermo García
- Richter Przemyslaw
- Rickards Hugh
- Rinaldi Carlo
- Rissling Ida
- Ritchie Stuart
- Rivera Susana Vázquez
- Riza-Soltani Tina Waldèn
- Rizzo Giovanni
- Robert Misericordia Floriach
- Robertson Dene
- Robertson Nicola
- Robowski Piotr
- Roca Alessandro
- Roca Elvira
- Roedig Verena
- Rogers Dawn
- Rojo Sebastián A
- Rola Rafal
- Romano Silvia
- Romero Irene
- Romoli Anna Maria
- Roos R A C
- Roos Raymund A C
- Rose Linda Ellison
- Rose Sarah
- Rosser Anne
- Rosser Elisabeth
- Rossi Fabiana
- Roth Jan
- Rothery Jean
- Roussel Martine
- Rowett Liz
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzińska Monika
- Russo Cinzia Valeria
- Ruíz Belén Garzón
- Ryglewicz Danuta
- Røren Niini
- Sablonnière Bernard
- Saft Carsten
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- San Martín Esther Suaréz
- Sando Botne
- Sandström Britta
- Santala Maire
- Santhouse Alastair
- Sass Christian
- Savage Lois
- Scaglione Cesa
- Scheibl Monika
- Scherer- Gagou Clarisse
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schrader Christoph
- Schrenk Caroline
- Schuierer Michele
- Schwenk Daniela
- Schöggl Helmut
- Schüpbach Michael
- Sciruicchio Vittorio
- Sebastián Ana Rojo
- Seliverstov Yury
- Sempołowicz Justyna
- Seppi Klaus
- Serpino Claudia
- Sienkiewicz-Jarosz Halina
- Sieradzan Kasia
- Silva Mark
- Simonin Clémence
- Simpson Sheila
- Sinadinosa Daniela
- Singh Baldev
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Snowden Julie
- Soleti Francesco
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltysiak Beverley
- Sorbi Sandro
- Souza Jennyde
- Spadaro Maria
- Spampinato Umberto
- Sprenger Fabienne
- Spruth Eike Jakob
- Squitieri Ferdinando
- Staffen Wolfgang
- Stamm Christiane
- Stattin Eva-Lena
- Stebler Yanik
- Steinmetz Gisèle
- Stenwak Agata
- Stokke Bodil
- Stompel Daniel
- Stopford Cheryl
- Storch Alexander
- Stubbe Lars
- Städtler Michael
- Stępniak Iwona
- Suarez María José Lama
- Summers Fiona
- Sundblom Jimmy
- Sułek Anna
- Svennigsson Per
- Svenningsson Per
- Swain Rachel
- Szczudlik Andrzej
- Szczygieł Elżbieta
- Szinwelski Michal
- Sánchez Jesús
- Sánchez Vicenta
- Sánchez Violeta Sánchez
- Süßmuth Sigurd
- Tabrizi S J
- Tabrizi Sarah
- Tacik Pawel
- Taylor Catherine
- Taylor Rachel
- Tedr- off Joakim
- Terol Santiago Durán-Sindreu
- Thibault-Tanchou Stéphanie
- Thomas Gareth
- Thompson Jennifer
- Thomson Aileen
- Tidswell Katherine
- Timóteo Ângela
- Tomasello Chiara
- Tommaso Marinade
- Torres Rodríguez María José
- Torres Antequera
- Toscano Jean
- Townhill Jenny
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhard Iris
- Tuuha Katri
- Tyvoll Hilde
- Uhrova T
- Ullah Jasmin
- Ure Alexandra
- Val Javier Lópezdel
- Valadas Anabela
- Valentine Ruth
- Valle Natalie
- van den Bogaard Simon J A
- van der Mast Rose C
- van Duijn Erik
- van Hout Monique S E
- van Reijen Dimphna
- van Vugt Jeroen P P
- Vandenberghe W
- Vandenberghe Wim
- Ventura Marta Fatás
- Verellen- Dumoulin C
- Vergara Mar Ruíz
- Vergé Luis Redondo
- Verny Christophe
- Verstraelen Nichola
- Viladrich Celia Mareca
- Villanueva Clara
- Vives Barbara
- Vuillaume Isabelle
- Wagner Caroline
- Wahlström J
- Wahlström Jan
- Walleczek Anna Maria
- Walsem Marleen Rvan
- Wannepain Sandrine
- Warner Thomas
- Weber Sabine
- Weert A Maritde
- Wehus Raghild
- Weindl Adolf
- Wenning Gregor
- Werner Cornelius J
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Widner Hkan
- Wiklund Leif
- Wikström Birgitta
- Wild Edward
- Wild Sue
- Winkelmann Juliane
- Winkler Jürgen
- Winnberg Elisabeth
- Witjes-Ané Marie-Noelle
- Witkowski Grzegorz
- Wiśniewski Bartłomiej
- Wolz Martin
- Wright Abigail
- Wright Jan
- Wójcik Magdalena
- Yarduiman Pam
- Yardumian Pam
- Yates Shona
- Yudina Elizaveta
- Yébenes Justo Garcíade
- Zaremba J
- Zaremba Jacek
- Zdzienicka Elzbieta
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Eugeniusz
- Zieora-Jakutowicz Karolina
- Zimmermann Marie- Agathe
- Zinzi Paola
- Zittel Simone
- Zucker Birgit
- Åman Jaana
- Økland Ellen
- Šašinková Pavla
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2013
- Field of study
Clinical manifestations of intermediate allele carriers in Huntington disease
- Author
- A Marit de Weert
- Aakta Patel
- Abigail Wright
- Abigail Wright
- Adriana Prundean
- Adrien Come
- Adrienne Curtis
- Agata Stenwak
- Agnieszka Gorzkowska
- Agnieszka Konkel
- Aicha Ghenam
- Alain Kaelin
- Aleksandra Kaczmarczyk
- Alessandro Roca
- Alexander Münchau
- Alexandra Ure
- Alexandre Eusebio
- Alice Seris
- Alison Kraus
- Alma Sikiric
- Alyson Andrew
- Alyson Bradbury
- Alzbeta Mühlbäck
- Amaia González
- Amy Palmer
- Ana Calado
- Ana García
- Ana Maria Finisterra
- Ana Maria Finisterra
- Ana Rojo Sebastián
- Ana Rojo Sebastián
- Ana Salgueiro
- Anabela Valadas
- Andrea Buck
- Andrea Ginestroni
- Andrea H Nemeth
- Andrea Horta-Barba
- Andrea Kesse
- Andrea Sollom
- Andrew Parkinson
- Andrzej Szczudlik
- Aneta Klimberg
- Angel Martínez Pueyo
- Anke Niess
- Anna Ciesielska
- Anna Gogol
- Anna Kaminska
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- Cristina Semedo
- Cubo E.
- Cynthia Butcher
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- Edward Wild
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- Ginette Cass
- Gioia Jacopini
- Giovanni Franco
- Giovanni Ristori
- Gisa Ellrichmann
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- Giuseppe De Michele
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- Ines Goerendt
- Inés Legarda Ramirez
- Irene Mazzante
- Irene Romero
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- Isabella Foustanos
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- Jacek Zaremba
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- Jamie Levey
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- Jean-Marc Burgunder
- Jean-Philippe Azulay
- Jennifer Thompson
- Jenny Callaghan
- Jenny Callaghan
- Jenny Callaghan
- Jenny Crooks
- Jenny de Souza
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- Jenny Townhill
- Jeremy Cosgrove
- Jeroen P P van Vugt
- Jerzy Marcinkowski
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- Jette Stockholm
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- Jillian Foster
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- Joaquim J Ferreira
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- Mandy Longthorpe
- Manuel Almeida
- Marco Massarelli
- Marco Paganini
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- Maria Bosca
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- Maria Ramos-Arroyo
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- Marta Para Prieto
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- Martina Di Renzo
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- Matthias Dose
- Maurizio Vezza
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- Monica Rodriguez Lopera
- Monika Rudzińska
- Monika Rudzińska
- Monique S E van Hout
- Mário Miguel Rosa
- Mónica Bascuñana
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- Nadia Peppa
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- Olivia J Handley
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- Rachel Taylor
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- Rafal Rola
- Ragnhild Wehus
- Rainer Hoffmann
- Ralf Marquard
- Ralf Reilmann
- Ramon Fernandez de Bobadilla
- Ramos-Arroyo M. A.
- Raphael M Bonelli
- Raymund A C Roos
- Raymund A C Roos
- Rebecca Minschke
- Reineke Bos
- Reineke Bos
- René Ribacoba
- Richard Armstrong
- Rocío García-Ramos García
- Rocío Malo de Molina
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- Ruth Fullam
- Ruth Fullam
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- Sabine Weber Zaugg
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- Sabrina Debruxelles
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- Salvadora Manzanares
- Samia Cheriet
- Sandra Gutierrez Romero
- Sandra Large
- Sandrine Rolland
- Sandro Sorbi
- Sara Minster
- Sara Minster
- Sarah Hunt
- Sarah J Tabrizi
- Sarah Rose
- Sarah Tabrizi
- Saul Martinez-Horta
- Saul Martinez-Horta
- Selene Capodarca
- Serge Jaumà Classen
- Shahbana Akhtar
- Sharon McDonnell
- Sheila A Simpson
- Shona Yates
- Sigrun Schepers
- Sigurd Süssmuth
- Silke Rumpf
- Silvia Piacentini
- Silvia Pradella
- Silvia Romano
- Silvio Peluso
- Simon J A van den Bogaard
- Simone Zittel
- Solveig Nepper
- Sonia Arribas Pardo
- Sonia González
- Sonja Trautmann
- Stefan Bohlen
- Stefania Bruno
- Stefanie Brown
- Stefanie Rohm
- Stephan Klebe
- Stephanie Hamer
- Stephen B Dunnett
- Stephen Dunnett
- Stuart Jamieson
- Sue McKenzie
- Sue Wild
- Suresh Komati
- Susan Huson
- Susana Pro Koivisto
- Susana Pro Koivisto
- Suzanne Lindquist
- Sébastien Charpentier
- Tecla Tucci
- Tereza Uhrova
- Thomas Musacchio
- Thomas Warner
- Thomasin Andrews
- Tiago Mendes
- Tiago Mestre
- Tiago Mestre
- Tiziana Martino
- Torsten Illmann
- Tua Vinther-Jensen
- Ulrika Høsterey-Ugander
- Umberto Spampinato
- Una Jones
- Uruj Anjum
- Ute Hidding
- Valentina Codella
- Valeria Piras
- Valérie Vaquie
- Verena Baake
- Verena Baake
- Veronica Puertas Martin
- Verónica Mañanes Barral
- Vicenta Sánchez
- Vittorio Sciruicchio
- Vivien Vaughn
- Walburgis Heinicke
- Wildson Vieira da Silva
- Wim Vandenberghe
- Wioletta Krysa
- Witold Soltan
- Yanik Stebler
- Yuri Seliverstov
- Zeid Mohammed
- Zosia Miedzybrodzka
- Zygmunt Jamrozik
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2016
- Field of study
Objective: There is controversy about the clinical consequences of intermediate alleles (IAs) in Huntington disease (HD). The main objective of this study was to establish the clinical manifestations of IA carriers for a prospective, international, European HD registry. Methods: We assessed a cohort of participants at risk with <36 CAG repeats of the huntingtin (HTT) gene. Outcome measures were the Unified Huntington's Disease Rating Scale (UHDRS) motor, cognitive, and behavior domains, Total Functional Capacity (TFC), and quality of life (Short Form-36 [SF-36]). This cohort was subdivided into IA carriers (27-35 CAG) and controls (<27 CAG) and younger vs older participants. IA carriers and controls were compared for sociodemographic, environmental, and outcome measures. We used regression analysis to estimate the association of age and CAG repeats on the UHDRS scores. Results: Of 12,190 participants, 657 (5.38%) with <36 CAG repeats were identified: 76 IA carriers (11.56%) and 581 controls (88.44%). After correcting for multiple comparisons, at baseline, we found no significant differences between IA carriers and controls for total UHDRS motor, SF-36, behavioral, cognitive, or TFC scores. However, older participants with IAs had higher chorea scores compared to controls (p 0.001). Linear regression analysis showed that aging was the most contributing factor to increased UHDRS motor scores (p 0.002). On the other hand, 1-year follow-up data analysis showed IA carriers had greater cognitive decline compared to controls (p 0.002). Conclusions: Although aging worsened the UHDRS scores independently of the genetic status, IAs might confer a late-onset abnormal motor and cognitive phenotype. These results might have important implications for genetic counseling. ClinicalTrials.gov identifier: NCT01590589
Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study
- Author
- \u160a\u161inkov\ue1 Pavla
- \u160enk\ue1rov\ue1 Zuzana
- \uc5man Jaana
- Aaserud Olaf
- Abbruzzese Giovanni
- Agarwal Veena
- Akhtar Shahbana
- Alarc\uf3n Moreau Mar\ueda Dolores
- Albanese Alberto
- Allain Philippe
- Almagro Carmen Ant\ufanez
- Almeida Manuel
- Alonso-Frech Fernando
- Alusi Sundus
- Anderson Mary
- Andersson Christian
- Andrade Carlos
- Andrew Alyson
- Andrews Thomasin
- Andrich J\ufcrgen
- Angeles Maria
- Aniola Jacek
- Anjum Uruj
- Annic Agn\ue8s
- Antczak Jakub
- Arbelo Jos\ue9 Mat\uedas
- Arkuszewski Michal
- Armstrong Richard
- Arntsen Vibeke
- Arques Penelope Navas
- Arran Natalie
- Artiga Mar\ueda Jos\ue9 Sainz
- Azulay Jean-Philippe
- B\ue1rcenas Antonio Herranz
- B\uf6ringer Regina
- Baake Verena
- Babiloni Blandine
- Bachmeier Michael
- Bachoud-L\ue9vi Anne-Catherine
- Badei Farideh
- Bailey Wendy
- Banaszkiewicz Krzysztof
- Bandmann Oliver
- Barbera Miquel Aguilar
- Barker Roger A.
- Barral Ver\uf3nica Ma\uf1anes
- Barrero Francisco
- Barth Katrin
- Barth\ue9l\ue9my Recka
- Bas Jordi
- Bechtel Natalie
- Beckmann Heike
- Bek Judith
- Bellonet Marcellin
- Benaich Sandra
- Benoit Alexandra
- Bentivoglio Anna Rita
- Berglund Maria
- Berglund Peter
- Bergmann Ulrike
- Berrisoul Hassan
- Bertini Elisabetta
- Bethwaite Pamela
- Betz Sabrina
- Beuth Markus
- Bioux Sandrine
- Biunno Ida
- Bj\uf6rnsson Elisabeth
- Bj\uf8rgo Kathrine
- Bj\uf8rnevoll Inga
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- Blinkenberg Ellen 8kland
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- Bohlen Stefan
- Boiss\ue9 Marie-Fran\ue7oise
- Bojakowska-Jaremek Kamila
- Bojarsky Jaime Kulisevsky
- Bonelli Raphael M.
- Bonneau Dominique
- Boogaerts Andrea
- Borge\uf8d Nancy
- Bos Reineke
- Bosca Maria
- Bosredon Cecile
- Bost Marie
- Boudali Lotfi
- Bove Francesco
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brice Alexis
- Brockie Peter
- Bronzova Juliana
- Brugada Francisco Castera
- Brugger Florian
- Bruno Stefania
- Bryl Anna
- Buchanan Lindsay
- Buck Andrea
- Buongiorno Mar\ueda Teresa
- Buratti Lisa
- Burguera Juan Andres
- Burgunder Jean-Marc
- Burn John
- Burrows Liz
- Busquets N\ufaria
- Busse Monica
- Butcher Cynthia
- Cabaret Maryline
- Calado Ana
- Calandra-Buonaura Giovanna
- Caldentey Juan Garc\ueda
- Callaghan Jenny
- Calopa Matilde
- Calvas Fabienne
- Calzado Noemi
- Campolongo Antonia
- Cannella Milena
- Capellari Sabina
- Capetian Philipp
- Capodarca Selene
- Cardoso Helena
- Carette Anne-Sophie
- Carri\ue8re Nicolas
- Carrillo F\ue1tima
- Carruesco Gemma Tome
- Casado Roc\uedo Villagr\ue1n
- Cass Ginette
- Castagliuolo Simona
- Castaldo Anna
- Catalli Claudio
- Catena Judit L\uf3pez
- Chabot Christelle
- Charles Perrine
- Charpentier S\ue9bastien
- Cheriet Samia
- Chu Carol
- Chu Elvina
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Classen Serge Jaum\ue1
- Clayton Carole
- Clenaghan Catherine
- Coarelli Giulia
- Codella Valentina
- Coebergh Jan
- Coelho Miguel
- Coleman Caroline
- Come Adrien
- Connemann Julia
- Constant Eric
- Constantinescu Radu
- Cormio Claudia
- Corrales Koldo Berganzo
- Cortegana Eva Mar\ueda Pacheco
- Cortelli Pietro
- Costa Andreia
- Costa Cristina
- Coulthard Elizabeth
- Courtin Fran\ue7oise
- Couttier Julien
- Craufurd David
- Craven Janet
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- D\ucdaz-Zorita Juan Pablo Tartari
- Da Silva Wildson Vieira
- Das Purkayastha Debasish
- Davidson Lynn
- Davies Rhys
- Davison Jill
- De Bobadilla Ramon Fernandez
- De Bruycker Christelle
- De Gregorio Francesca
- De La Cerda Santa Mar\ueda Andr\ue9s
- De Langavant Laurent Cleret
- De Michele Giuseppe
- De Molina Roc\uedo Malo
- De Nicola Annunziata
- De Souza Keylock Jenny
- De Tommaso Marina
- De Weert A. Marit
- De Y\ue9benes Justo Garc\ueda
- Debilly B\ue9reng\ue8re
- Debruxelles Sabrina
- Dec Malgorzata
- Decorte Eric
- Dedich\ue1 Nadia Rodr\uedguez
- Defebvre Luc
- Deith Catherine
- Dekker Meike
- Del Mar Fenollar Mar\ueda
- Del Valle Loarte Mar\ueda
- Delabaere Hel\ue8ne
- Delaigue Christine
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Demonet Jean-Fran\ue7ois
- Depelchin Aliz\ue9
- Destee Alain
- Dewulf-Pasz Nelly
- DI Bella Daniela
- DI Donato Stefano
- DI Giacopo Raffaella
- DI Maio Luigi
- DI Maria Emilio
- DI Pietro Anna Gerrtiz
- DI Poggio Monica Bandettini
- DI Renzo Martina
- DI\ue9guez Esther
- DIas Margarida
- DIercks Gabriele
- DIfruscolo Olimpia
- DIpple Heather
- Doherty Karen
- Dondaine Thibaut
- Donovan John O
- Dose Matthias
- Dougherty Andrew
- Downie Lorna
- Dramstad Elisabeth
- Dressler DIrk
- Duch\ue9 Charlotte
- Dugauquier Florence
- Duits Annelien
- Dujardin Kathy
- Dumas Eve M.
- Dunnett Stephen
- Dupuis Michel
- Durif Franck
- Durr Alexandra
- Duru C\ue9cile
- Dziadkiewicz Artur
- Ecker Daniel
- Eddy Charlotte
- Edwards Maureen
- Edwards Rachel
- Eklund Pia
- Ekwall Camilla
- Elifani Francesca
- Ellrichmann Gisa
- Esposito Federica
- Esteban Juan Carlos Gomez
- Eusebio Alexandre
- Evans Carole
- Ewenczyk Claire
- Fairtlough Helen
- Fannemel Madeleine
- Farewell Daniel
- Fasano Alfonso
- Fasquel V\ue9ronique
- Fernandez Cristina Melgar
- Ferraldeschi Michela
- Ferrandes Giovanna
- Ferreira Joaquim J
- Ferrer Pilar Quil\ue9z
- Figuerola Bego\uf1a Jeweinat
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flament M\ue9lanie
- Fletcher Amy
- Fluchere Fr\ue9d\ue9rique
- Fortuna Lorenza
- Foster Jillian
- Foustanos Isabella
- Foy Kevin
- Frades Bel\ue9n
- Francis Flverly
- Francisque H\ue9l\ue8ne
- Franco Giovanni
- Frech Fernando Alonso
- Fredlund Gunnel
- Freire-Patino Dawn
- Frich Jan C.
- Frontali Marina
- Frost Julie
- Fullam Ruth
- Fuller Kathleen
- G\uf6ller Marie-Lousie
- G\uf6pfert Nicole
- G\uf8rvell Per F.
- Gago Miguel
- Gallassi Roberto
- Gallentree Deena
- Ganos Christos
- Garc\ueda Ana
- Garc\ueda Roc\uedo Garc\ueda-Ramos
- Garcia-Amigot Fermin
- Garde M\uf3nica Bascu\uf1ana
- Garrett Carolina
- Gaston Itziar
- Gayde-Stephan Sabine
- Geitner Carolin
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Genoves Camille
- Gerrans Emily
- Ghelli Elena
- Gil Acera
- Gill Paul
- Gillardin Anne-Fran\ue7oise
- Gilling Mette
- Ginestroni Andrea
- Girard Carole
- Giuliano Joe
- Godefroy Olivier
- Goerendt Ines
- Gogol Anna
- Gohier B\ue9n\ue9dicte
- Goizet Cyril
- Golding Charlotte
- Gonz\ue1lez Amaia
- Gonz\ue1lez Laura Vargas
- Gonz\ue1lez Sonia
- Good Jean-Marc
- Goodman Anna
- Gorzkowska Agnieszka
- Gorzolla Heike
- Goudie David
- Gowers Lesley
- Grabska Natalia
- Grosjean H\ue9l\ue8ne
- Gu\ue9rid Marie-Anne
- Guedes Leonor Correia
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guimar\ue3es Joana
- Guisasola Luis Men\ue9ndez
- Gunner Kerry
- Guyant-Mar\ue9chal Lucie
- Guzman Natalie Valle
- H\uf6lzner Eva
- H\uf8sterey-Ugander Ulrika
- Haider Salman
- Haig-Brown DIane
- Hallam Caroline
- Hamer Stephanie
- Hametner Eva-Maria
- Handley Olivia J.
- Hannequin DIdier
- Hannier V\ue9ronique
- Harding Alison
- Hare Marianne
- Harris Kayla
- Harrison David
- Harrower Timothy
- Hart't Ellen P.
- Hartikainen Paivi
- Haug Marte Gj\uf8l
- Hauge Erik
- Hayward Beverley
- Hayward Elaine
- Hecht Karen
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Hensman Davina
- Hepperger Caroline
- Hermoso F\ue1tima Damas
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Dur\ue1n
- Herrmann Lennard
- Heywood Melanie
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Hjermind Lena
- Ho Carrie
- Hobson Emma
- Hoffmann Rainer
- Hofstetter Nina
- Holas Christiane
- Holl Anna
- Holmans Peter
- Hopes Lucie
- Hotter Anna
- Howard Liz
- Hughes Alis
- Hughes Max
- Hunger Ulrike
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Hvalstedt Carina
- Hypp\uf6nen Hannele
- Ialongo Tamara
- Idiago Jes\ufas Miguel Ruiz
- Ignatius Jaakko
- Illarioshkin Sergey
- Illmann Torsten
- Ireland Jane
- Irvine Sarah
- J\ue4\ue4skalainen Outi
- J\ufalio Filipa
- Jachinska Katarzyna
- Jack Roisin
- Jacobsen Oda
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Janu\ue1rio Cristina
- Jasi\u144ska-Myga Barbara
- Jauffret C\ue9line
- Johns Nicola
- Johnson Liz
- Jones Lesley
- Jones Mary
- Jones Una
- Jourdain S\ue9verine
- Jung Hans H.
- Justo Damian
- K\ue4rpp\ue4 Mikko
- Kaczmarczyk Aleksandra
- Kaelin Alain
- Kaiserova Michaela
- Kajula Outi
- Kaminska Anna
- Kaminski Barbara
- Kammel Gerit
- Kampstra Anne
- Kapfhammer Hans-Peter
- Kassar Abdulrahman
- Kavalier Fred
- Kazoka Mbombe
- Kesse Andrea
- Keys Liane
- Khalil Hanan
- Kipps Christopher
- Klebe Stephan
- Klemp\ued\u159 Ji\u159\ued
- Klimberg Aneta
- Klodowska-Duda Gabriela
- Klooster Jesper
- Knight Caroline
- Kohl Zacharias
- Koivisto Susana Pro
- Komati Suresh
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kozay Christina
- Kramer Bianca
- Kraus Alison
- Kraus Peter
- Krawczyk Malgorzata
- Kremer Berry
- Krishnamoorthy Ashok
- Krysa Wioletta
- Krystkowiak Pierre
- Kubowicz Ewelina
- Kwiecinski Hubert
- L\ue9onard Marie-Claude
- L\uf3pez Rosa Guerrero
- L\uf6hle Matthias
- L\ufcsebrink Antje
- Ladurner Gunther
- Lafoucri\ue8re Danielle
- Lagha-Boukbiza Ouhaid
- Lahiri Nayana
- Laing Hana
- Lamanna Claudia
- Lambeck Johann
- Landwehrmeyer Bernhard
- Lange Herwig
- Larcher Barbara
- Large Sandra
- Larsen Ida Unmack
- Lashwood Alison
- Laur\ue1 Matilde
- Laver Fiona
- Leenders Nico
- Legendre Perrine
- Lemaire Marie-H\ue9l\ue8ne
- Lemoine Laurie
- Lemos Mar\ueda Dolores Romero
- Lesne Fabien
- Levey Jamie
- Lewerenz Jan
- Lewis Monica
- Leypold Christine
- Lezius Franziska
- Ligon-Auer Maria
- Lilek Sabine
- Lilek Stefan
- Lindquist Suzanne
- Linnsand Petra
- Loiseau Sylvie
- Lolk Annette
- Longato Nadine
- Longinus Bernhard
- Longthorpe Mandy
- Lopera Monica Rodriguez
- Loria Giovanna
- Loutfi Ghada
- Lovo Francesca
- Lozano Pablo S\ue1nchez
- Lucena Carolina Mendez
- Lundsgaard Marianne
- M\ue4chtel Miriam
- M\uf8ller Anette Torvin
- M\ufchlau Mark
- M\ufchlb\ue4ck Alzbeta
- M\ufcller Christoph
- M\ufcller Nicole
- M\ufcnchau Alexander
- M\ufcnkel Kristina
- M\ufctze Lisanne
- Maass Antonia
- MacKinnon Lesley
- Madsen Louise Hasselstr\uf8m
- Magnet Markus
- Mahlknecht Philipp
- Maiwald Robert
- Majeed Tahir
- Majerov\ue1 Veronika
- Malec-Litwinowicz Michalina
- Malt\ueate David
- Mandich Paola
- Mandich Paola
- Manouvrier Sylvie
- Mantaux B\ue9atrice
- Manzanares Salvadora
- Marcel Christophe
- Marchese Roberta
- Marcinkowski Jerzy
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Marquard Ralf
- Mart\uedn Idaira
- Mart\uednez Noelia Rodr\uedguez
- Mart\uednez-Descals Asunci\uf3n
- Martikainen Kirsti
- Martin Veronica Puertas
- Martinez-Horta Saul
- Martinez-Jaurrieta Maria Dolores
- Martino Tiziana
- Mason Sarah
- Massano Jo\ue3o
- Massarelli Marco
- Mata Maite Paredes
- Matheson Kirsty
- Mazzante Irene
- McDonnell Sharon
- McEntagart Meriel
- McFadyen Paula
- McGill Marie
- McKenzie Sue
- McLean Tim
- McNulty Paul
- Mechi Claudia
- Meier Simone
- Meireles Joana
- Mendes Tiago
- Merino Beatriz Tijero
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Mihaylova Violeta
- Milani Paolo
- Milkereit Eva
- Minet C\ue9cile
- Minschke Rebecca
- Minster Sara
- Mir Pablo
- Modoni Anna
- Mohammed Zeid
- Moilanen Jukka
- Monin Marie-Lorraine
- Monteiro Ana
- Monza Daniela
- Morales Blas
- Moreno Jos\ue9 Luis L\uf3pez-Send\uf3n
- Moreno Jose Manuel Garc\ueda
- Moreno Patrocinio Garcia
- Morgado Graca
- Morgado Joana
- Morgan Karen
- Mu\uf1oz Esteban
- Mu\uf1oz Juan Mar\uedn
- Mundler Laura
- Murphy Helen
- Musacchio Thomas
- Musgrave Hannah
- Mustonen Aki
- Mutez Eug\ue9nie
- N\uf6th Kerstin
- Nanetti Lorenzo
- Necuiniate Renata
- Neleborn-Lingefj\ue4rd Liselotte
- Nemeth Andrea H
- Nepper Solveig
- Nevitt Louise
- Nielsen J\uf8rgen
- Niess Anke
- Noad Rupert
- Novak Marianne
- Nowak Malgorzata
- Nowak Marielle
- Nyberg Clara
- O'Donovan Kirsty
- O'Keefe Deidre
- O'Neill Mari
- Oehmen Martin
- Olivier Audrey
- Ollokainen Mari
- Olofsson Carina
- Oosterloo Mayke
- Opala Grzegorz
- Orth Michael
- Ossig Christiana
- Otti Daniela
- Oughton Emma
- Owen Michael
- P\ue4iv\ue4rinta Markku
- P\ue5lhagen Sven
- Padieu Helene
- Paganini Marco
- Pagonabarraga Javier
- Painold Annamaria
- Palanca Paloma Millan
- Palmer Amy
- Panzeri Marta
- Pardo Sonia Arribas
- Paridi Dominga
- Pariente J\ue9r\ue9mie
- Parkinson Andrew
- Partington-Jones Lucy
- Pastor Barbara Vives
- Pate Louise
- Patel Aakta
- Paterski Laurent
- Patton Michael
- Paucar Martin
- Paus Karin
- Pe\uf1a Jos\ue9 Chac\uf3n
- Peacy Caroline
- Pearson Pauline
- Peinemann Alexander
- Peippo Maarit
- Peluso Silvio
- Peppa Nadia
- Perea Fuensanta Noguera
- Perez Jesus Perez
- Peria\uf1ez Juan Manuel
- Peter Mireille
- Petersen Jens A.
- Peterson Maria
- Petracca Martina
- Petrollini Martina
- Phillipps Cl\ue9lie
- Phillips Michelle
- Piacentini Silvia
- Piano Carla
- Piccininni Chiara
- Pierre Mich\ue8le
- Pilcher Richard
- Pinter Bernadette
- Playe Alicia
- Plomhause Lucie
- Poda Roberto
- Poewe Werner
- Polo Cecilia Gil
- Porteous Mary
- Pouliquen Doroth\ue9e
- Powell Kingsley
- Pr\ufc f Harald
- Pradella Silvia
- Price Kathleen
- Prieto Marta Para
- Priller Josef
- Probst Daniela
- Prouzet Julie
- Prundean Adriana
- Pueyo Angel Mart\uednez
- Quaranta Davide
- Quarrell Oliver
- R\uf8ren Niini
- R\uf8sby Oddveig
- Rae Daniela
- Rakowicz Maryla
- Raman Ashok
- Ramesh Raviram
- Ramirez In\ue9s Legarda
- Ramos-Arroyo Maria Antonia
- Raseta Rolland
- Redondo Luis
- Redondo Mar\ueda Teresa C\ue1ceres
- Reetz Kathrin
- Regeur Lisbeth
- Reilmann Ralf
- Reisinger Karin
- Reiter Eva-Magdalena
- Retterst\uf8l Lars
- Riba\uef Pascale
- Ribacoba Ren\ue9
- Ribas Guillermo Garc\ueda
- Ribbat Michael
- Ribosa Roser
- Richter Przemyslaw
- Rickards Hugh
- Rijntjes Michel
- Rinaldi Carlo
- Rindal Beate
- Ristori Giovanni
- Ritchie Stuart
- Robert Misericordia Floriach
- Robertson Dene
- Robertson Nicola
- Robowski Piotr
- Roca Alessandro
- Roca Elvira
- Rogers Dawn
- Rohm Stefanie
- Rola Rafal
- Rolland Sandrine
- Romano Silvia
- Romero Irene
- Romero Sandra Gutierrez
- Romoli Anna Maria
- Roos Raymund A. C.
- Rose Sarah
- Rosser Anne
- Rosser Elisabeth
- Roth Jan
- Rothery Jean
- Roussel Martine
- Rowett Liz
- Roze Emmanuel
- Ru\uedz Pedro Jos\ue9 Garc\ueda
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzi\u144ska Monika
- Rumpf Silke
- Russo Cinzia Valeria
- Ryglewicz Danuta
- S\ue1nchez Vicenta
- S\ue1nchez Violeta S\ue1nchez
- S\ufcssmuth Sigurd
- Sablonni\ue8re Bernard
- Saft Carsten
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- Sando Sigrid Botne
- Santacruz Pilar
- Santala Maire
- Santhouse Alastair
- Sass Christian
- Savage Lois
- Scaglione Cesa
- Sch\uf6ggl Helmut
- Sch\ufcler B\ue9atrice
- Sch\ufcpbach Michael
- Scheibl Monika
- Schepers Sigrun
- Scherer-Gagou Clarisse
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schneider Ariane
- Schoonderbeek Anne
- Schrader Christoph
- Schwenk Daniela
- Sciruicchio Vittorio
- Sebasti\ue1n Ana Rojo
- Seliverstov Yury
- Semedo Cristina
- Sempolowicz Justyna
- Seppi Klaus
- Serpino Claudia
- Sevilla Maria Ascension Zea
- Sienkiewicz-Jarosz Halina
- Sieradzan Kasia
- Sikiric Alma
- Silva Mark
- Simonelli Maria
- Simonin Cl\ue9mence
- Simpson Sheila A
- Simpson Steve
- Sinadinosa Daniela
- Singh Baldev
- Sipponen Marjett
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Smalley Sarah
- Snowden Julie
- Sol\ueds Pilar
- Soleti Francesco
- Solito Marcella
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltysiak Beverley
- Sorbi Sandro
- Sorrentino Pierpaolo
- Spadaro Maria
- Spagnolo Francesca
- Spampinato Umberto
- Sprenger Fabienne
- Spruth Eike
- Squitieri Ferdinando
- St 9pniak Iwona
- St\ue4dtler Michael
- St\uf8rseth Hanna Haugan
- Staffen Wolfgang
- Stamm Christiane
- Stattin Eva-Lena
- Stebler Yanik
- Steinmetz Gis\ue9le
- Stenwak Agata
- Stockholm Jette
- Stokke Bodil
- Stompel Daniel
- Stopford Cheryl
- Storch Alexander
- Stubbe Lars
- Sulek Anna
- Summers Fiona
- Sundblom Jimmy
- Svenningsson Per
- Swain Rachel
- Szczudlik Andrzej
- Szczygiel Elzbieta
- Szinwelski Michal
- Tabrizi Sarah
- Tacik Pawel
- Tard C\ue9line
- Taroni Franco
- Tataru Alina
- Taylor Anne-Marie
- Taylor Cat
- Taylor Rachel
- Tchikviladz\ue9 Maya
- Thibault-Tanchou St\ue9phanie
- Thiel Silvia
- Thomas Gareth
- Thompson Jennifer
- Thomson Aileen
- Tidswell Katherine
- Timewell Erika
- Timings Leanne
- Tir M\ue9lissa
- Tomasello Chiara
- Tonner Alison
- Torlizzi Flavia
- Torres Mar\ueda Martirio Antequera
- Toscano Jean
- Townhill Jenny
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhard Iris
- Tucci Tecla
- Tuuha Katri
- Tyvoll Hilde
- Udaeta Beatriz
- Uhrova Tereza
- Ulla Miguel
- Ullah Jasmin
- Ure Alexandra
- Valadas Anabela
- Valentine Ruth
- Van De Wyngaerde Fran\ue7oise
- Van Den Bogaard Simon J. A.
- Van Hout Monique S. E.
- Van Oostrom Joost
- Van Paemel Dominique
- Van Reijen Dimphna
- Van Vugt Jeroen P. P.
- Van Walsem Marleen
- Vandenberghe Wim
- Vangsted-Hansen Christina
- Vaughan Vivien
- Ventura Marta Fat\ue1s
- Verellen-Dumoulin Christine
- Verhoeven Marloes
- Vernon Nathan
- Verny Christophe
- Verstappen Carla
- Verstraelen Nicola
- Vezza Maurizio
- Vidal Tiphaine
- Viladrich C\ue8lia Mareca
- Vilaplana Carmen Peir\uf3
- Villa Riballo Antonio
- Villa Carolina
- Villanueva Clara
- Villanueva Marina \uc1vila
- Vingerhoets Francois
- Vinther-Jensen Tua
- Vivancos Laura
- Vogel Melanie
- Vuillaume Isabelle
- W\uf3jcik Magdalena
- Waber Mirella
- Wagner Caroline
- Wahlstr\uf6m Jan
- Wallden Tina
- Walleczek Anna Maria
- Wannepain Sandrine
- Warner Thomas
- Wasielewska Anna
- Weber Nathalia
- Weekes Rebecca
- Wehus Ragnhild
- Weindl Adolf
- Wenning Gregor
- Wermuth Lene
- Werner Cornelius J.
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Wi\u15bniewski Bartlomiej
- Wider Christian
- Wikstr\uf6m Birgitta
- Wild Edward
- Wild Sue
- Williams Josh
- Winkelmann Juliane
- Winkler J\ufcrgen
- Witjes-An\ue9 Marie-Noelle
- Witkowski Grzegorz
- Wolz Annett
- Wolz Martin
- Wood Josh
- Wright Abigail
- Wright Jan
- Yardumian Pam
- Yates Shona
- Youssov Katia
- Yudina Elizaveta
- Zaremba Jacek
- Zaugg Sabine Weber
- Zdzienicka Elzbieta
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Eugeniusz
- Zimmermann Marie-Agathe
- Zinzi Paola
- Ziora-Jakutowicz Karolina
- Zittel Simone
- Zucker Birgit
- Publication venue
- 'IOS Press'
- Publication date
- 01/01/2018
- Field of study
Background: People with Huntington's disease (HD) have been observed to have lower rates of cancers. Objective: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. Methods: Data were obtained from the European Huntington's disease network REGISTRY study for 6540 subjects. Population cancer incidence was ascertained from the GLOBOCAN database to obtain standardised incidence ratios of cancers in the REGISTRY subjects. Results: 173/6528 HD REGISTRY subjects had had a cancer diagnosis. The age-standardised incidence rate of all cancers in the REGISTRY HD population was 0.26 (CI 0.22-0.30). Individual cancers showed a lower age-standardised incidence rate compared with the control population with prostate and colorectal cancers showing the lowest rates. There was no effect of CAG length on the likelihood of cancer, but a cancer diagnosis within the last year was associated with a greatly increased rate of HD onset (Hazard Ratio 18.94, p < 0.001). Conclusions: Cancer is less common than expected in the HD population, confirming previous reports. However, this does not appear to be related to CAG length in HTT. A recent diagnosis of cancer increases the risk of HD onset at any age, likely due to increased investigation following a cancer diagnosis
Cognitive decline in Huntington's disease expansion gene carriers
- Author
- Aanonsen Nils Olaf
- Aaserud Olaf
- Abbruzzese Giovanni
- Akhtar Shahbana
- Alarcón Moreau María Dolores
- Albanese Alberto
- Allain Philippe
- Almagro Carmen Antúnez
- Alonso-Frech Fernando
- Andrade Carlos
- Andrews Thomasin
- Andrich Jürgen
- Anheim Mathieu
- Anjum Uruj
- Annic Agnès
- Antczak Jakub
- Arbelo José Matías
- Arkuszewski Michał
- Armstrong Richard
- Arntsen Vibeke
- Arques Penelope Navas
- Arran Natalie
- Artiga María José Sainz
- Azulay Jean-Philippe
- Baake Verena
- Babiloni Blandine
- Bachmeier Michael
- Bachoud-Lévi Anne-Catherine
- Badei Farideh
- Banaszkiewicz Krzysztof
- Bandmann Oliver
- Barbera Miquel Aguilar
- Barker Roger A.
- Barral Verónica Mañanes
- Barrero Francisco
- Barth Katrin
- Barthélémy Recka
- Bartoli Caterina
- Barun Nadia
- Bas Jordi
- Bascuñana Mónica
- Bechtel Natalie
- Beckmann Heike
- Bek Judith
- Bellonet Marcellin
- Benaich Sandra
- Benoit Alexandra
- Bentivoglio Anna Rita
- Bentivoglio Anna-Rita
- Berglund Maria
- Berglund Måns
- Berglund Peter
- Bergmann Ulrike
- Bernard Tomáš
- Berrisoul Hassan
- Bertini Elisabetta
- Bethwaite Pamela
- Betz Sabrina
- Beuth Markus
- Bioux Sandrine
- Biunno Ida
- Bjørgo Kathrine
- Bjørnevoll Inga
- Bliaux Evangeline
- Blin Stéphanie
- Blinkenberg Ellen Økland
- Blondeau Leily
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen Stefan
- Boissé Marie-Françoise
- Bojakowska-Jaremek Kamila
- Bojarsky Jaime Kulisevsky
- Bonelli Raphael M.
- Bonneau Dominique
- Borgeød Nancy
- Bos Reineke
- Bosca Maria
- Bosredon Cecile
- Bost Marie
- Boster Sarah
- Boudali Lotfi
- Bove Francesco
- Boćwińska Dorota
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brice Alexis
- Brockie Peter
- Bronzova Juliana
- Brown Pauline
- Brown Stefanie
- Brugger Florian
- Bruno Stefania
- Bruycker Christelle De
- Bryl Jacek Anioła Anna
- Buchanan Lindsay
- Buck Andrea
- Buongiorno María Teresa
- Buratti Lisa
- Burguera Juan Andres
- Burgunder Jean-Marc
- Burrows Liz
- Busquets Núria
- Busse Monica
- Butcher Cynthia
- Bárcenas Antonio Herranz
- Böringer Regina
- Bürk Katrin
- Błaszczyk Magdalena
- Cabaret Maryline
- Calandra-Buonaura Giovanna
- Caldentey Juan García
- Callaghan Jenny
- Calopa Matilde
- Calvas Fabienne
- Calzado Noemi
- Campolongo Antonia
- Cannella Milena
- Capellari Sabina
- Capetian Philipp
- Capodarca Selene
- Carette Anne-Sophie
- Carrière Nicolas
- Carruesco Gemma Tome
- Cass Ginette
- Castagliuolo Simona
- Castaldo Anna
- Catalli Claudio
- Catena Judit López
- Cavaco Sara
- Cação Gonçalo
- Chabot Christelle
- Charles Perrine
- Cheriet Samia
- Chiara Piccininni
- Chu Carol
- Chu Elvina
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Classen Serge Jaumà
- Clayton Carole
- Clenaghan Catherine
- Coarelli Giulia
- Codella Valentina
- Coebergh Jan
- Coelho Miguel
- Come Adrien
- Connemann Julia
- Constantinescu Radu
- Cormio Claudia
- Cortegana Eva María Pacheco
- Cortelli Pietro
- Cosgrove Jeremy
- Costa Andreia
- Coulthard Elizabeth
- Courtin Françoise
- Couttier Julien
- Craufurd David
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- D'Alessio Barbara
- Da Silva Vieira
- Damásio Joana
- Das Purkayastha Debasish
- Davidson Lynn
- Davison Jill
- De Bobadilla Ramon Fernandez
- De Gregorio Francesca
- De La Cerda Santa María Andrés
- De Langavant Laurent Cleret
- De Michele Giuseppe
- De Molina Rocío Malo
- De Nicola Annunziata
- De Souza Jenny
- De Tommaso Marina
- De Weert A. Marit
- Debilly Bérengère
- Debruxelles Sabrina
- Dec Małgorzata
- Decorte Eric
- Dedichá Nadia Rodríguez
- Defebvre Luc
- Deith Catherine
- Dekker Meike
- Del Mar Fenollar María
- Del Val Fernandez Javier
- Del ValleLoarte María
- Delabaere Helène
- Delaigue Christine
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Demonet Jean-François
- Depelchin Alizé
- Descals Asunción Martínez
- Destee Alain
- Dewulf-Pasz Nelly
- Deyebenes Justo García
- Di Bella Daniela
- Di Donato Stefano
- Di Giacopo Raffaella
- Di Maio Luigi
- Di Maria Emilio
- Di Poggio Monica Bandettini
- Di Renzo Martina
- Dieguez Esther
- Diercks Gabriele
- Difruscolo Olimpia
- Dipple Heather
- Dixon Kathryn
- Doherty Karen
- Dondaine Thibaut
- Donovan John O.
- Dose Matthias
- Dougherty Andrew
- Downie Lorna
- Dramstad Elisabeth
- Dressler Dirk
- Duché Charlotte
- Duda Gabriela Kłodowska E.
- Dugauquier Florence
- Duits Annelien
- Dujardin Kathy
- Dumas Eve M.
- Dunnett Stephen
- Dunnett Stephen B.
- Dupuis Michel
- Durif Franck
- Durr Alexandra
- Duru Cécile
- Dziadkiewicz Artur
- Díaz-Zorita Juan Pablo Tartari
- Ecker Daniel
- Eddy Charlotte
- Edwards Maureen
- Edwards Rachel
- Eklund Pia
- Ekwall Camilla
- Elifani Francesca
- Ellrichmann Gisa
- Esposito Chiara
- Eusebio Alexandre
- Evans Carole
- Ewenczyk Claire
- Fairtlough Helen
- Fannemel Madeleine
- Fasano Alfonso
- Fasquel Véronique
- Feliz Cici Feliz
- Fernandes Joana
- Ferraldeschi Michela
- Ferrandes Giovanna
- Ferreira Joaquim J.
- Ferrer Pilar Quiléz
- Figuerola Begoña Jeweinat
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flament Mélanie
- Fletcher Amy
- Fluchere Frédérique
- Fortuna Lorenza
- Fortunato Fernanda
- Foster Jillian
- Foustanos Isabella
- Frades Belén
- Francis Flverly
- Francisque Hélène
- Franco Giovanni
- Frech Fernando Alonso
- Fredlund Gunnel
- Freire-Patino Dawn
- Frich Jan
- Frich Jan C.
- Frontali Marina
- Fullam Ruth
- Fuller Kathleen
- Fullerton Neil
- Gago Miguel
- Gallantree Deena
- Gallassi Roberto
- Gallentree Deena
- Ganos Christos
- Garcia-Amigot Fermin
- García Ana
- García Rocío García-Ramos
- Garreau Christine
- Garrett Carolina
- Gaston Itziar
- Gayde-Stephan Sabine
- Geitner Carolin
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Genoves Camille
- Gerrtiz Anna
- Gethin Louise
- Ghelli Elena
- Gill Paul
- Gilling Mette
- Ginestroni Andrea
- Girard Carole
- Giuliano Joe
- Godefroy Olivier
- Goerendt Ines
- Gogol Anna
- Gohier Bénédicte
- Goizet Cyril
- Golding Charlotte
- González Sonia
- Goodman Anna
- Gorospe Aránzazu
- Gorzkowska Agnieszka
- Gorzolla Heike
- Goudie David
- Gowers Lesley
- Grabska Natalia
- Grosjean Hélène
- Guedes Leonor Correia
- Guenam Aicha
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guimarães Joana
- Guisasola Luis Menéndez
- Guyant-Maréchal Lucie
- Guzman Natalie Valle
- Guérid Marie-Anne
- Göller Marie-Lousie
- Göpfert Nicole
- Gørvell Per F.
- Haggag Kathrine
- Haider Salman
- Hallam Caroline
- Hamer Stephanie
- Hametner Eva-Maria
- Handley Olivia J.
- Hannequin Didier
- Hannier Véronique
- Harding Alison
- Hare Marianne
- Harrison David
- Harrower Timothy
- Hartikainen Paivi
- Haug Marte Gjøl
- Hauge Erik
- Hayward Beverley
- Hecht Karen
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Hensman Davina
- Hepperger Caroline
- Hermoso Fátima Damas
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Duran
- Herrmann Lennard
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Ho Carrie
- Hobson Emma
- Hoffmann Rainer
- Hofstetter Nina
- Holas Christiane
- Holl Anna
- Holmes Katrina
- Hopes Lucie
- Hotter Anna
- Howard Liz
- Hughes Max
- Hunger Ulrike
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Hvalstedt Carina
- Hyppönen Hannele
- Hölzner Eva
- Høsterey-Ugander Ulrika
- Ialongo Tamara
- Idiago Jesús Miguel Ruiz
- Illarioshkin Sergey
- Illmann Torsten
- Ireland Jane
- Irvine Sarah
- Jachinska Katarzyna
- Jack Roisin
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Januário Cristina
- Jasińska-Myga Barbara
- Jauffret Céline
- Johannessen Cecilie Haggag
- Johns Nicola
- Johnson Liz
- Jones Lesley
- Jones Mary
- Jones Una
- Jourdain Séverine
- Jung Hans H.
- Justo Damian
- Júlio Filipa
- Kaczmarczyk Aleksandra
- Kaelin Alain
- Kaminska Anna
- Kaminski Barbara
- Kammel Gerit
- Kampstra Anne
- Kapfhammer Hans-Peter
- Kassar Abdulrahman
- Kavalier Fred
- Kazoka Mbombe
- Kesse Andrea
- Khalil Hanan
- Klebe Stephan
- Klempír Jirí
- Klimberg Aneta
- Klooster Jesper
- Knight Caroline
- Kohl Zacharias
- Koivisto Susana Pro
- Komati Suresh
- Konkel Agnieszka
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kozay Christina
- Kramer Bianca
- Kraus Alison
- Kraus Peter
- Krawczyk Malgorzata
- Kremer Berry
- Krishnamoorthy Ashok
- Krysa Wioletta
- Krystkowiak Pierre
- Kubowicz Ewelina
- Kwiecinski Hubert
- Ladurner Gunther
- Lafoucrière Danielle
- Lagha-Boukbiza Ouhaid
- Lahiri Nayana
- Laing Hana
- Lamanna Claudia
- Lambeck Johann
- Landwehrmeyer Bernhard
- Landwehrmeyer G. Bernhard
- Lange Herwig
- Larcher Barbara
- Large Sandra
- Lashwood Alison
- Lau Puay Ngoh
- Laurà Matilde
- Laver Fiona
- Leenders Nico
- Legendre Perrine
- Lemaire Marie-Helene
- Lemoine Laurie
- Lesne Fabien
- Levey Jamie
- Lewerenz Jan
- Lewin Kajsa
- Lewis Monica
- Lezius Franziska
- Ligon-Auer Maria
- Lilek Sabine
- Lilek Stefan
- Linnsand Petra
- Loiseau Sylvie
- Longato Nadine
- Longinus Bernhard
- Longthorpe Mandy
- Lopera Monica Rodriguez
- Loria Giovanna
- Loureiro Rui
- Loutfi Ghada
- Lovo Francesca
- Lozano Pablo Sánchez
- Lucena Carolina Mendez
- López Rosa Guerrero
- Löhle Matthias
- Lüsebrink Antje
- Maass Antonia
- Magalhães Marina
- Magnet Markus
- Mahlknecht Philipp
- Maiwald Robert
- Majeed Tahir
- Majerová Veronika
- Malec-Litwinowicz Michalina
- Maltête David
- Mandich Paola
- Manouvrier Sylvie
- Mantaux Béatrice
- Manzanares Salvadora
- Marcel Christophe
- Marchese Roberta
- Marcinkowski Jerzy
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Marquard Ralf
- Martikainen Kirsti
- Martin Veronica Puertas
- Martinez-Horta Saul
- Martinez-Jaurrieta Maria Dolores
- Martino Tiziana
- Martín Idaira
- Martínez Noelia Rodríguez
- Martínez-Descals Asunción
- Mason Sarah
- Massano João
- Massarelli Marco
- Matheson Kirsty
- Mazzante Irene
- Mcdonnell Sharon
- Mcentagart Meriel
- Mcfadyen Paula
- Mcgill Marie
- Mckenzie Sue
- Mclean Tim
- Mechi Claudia
- Meier Simone
- Meireles Joana
- Mendes Tiago
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Mihaylova Violeta
- Milani Paolo
- Milkereit Eva
- Minet Cécile
- Minschke Rebecca
- Minster Sara
- Modoni Anna
- Mohammed Zeid
- Monin Marie-Lorraine
- Monteiro Ana
- Monza Daniela
- Morales Blas
- Moreira Inês
- Moreno José Luis Lópeze-Sendón
- Moreno José Manuel García
- Moreno Patrocinio Garcia
- Morgado Graca
- Morgan Karen
- Mundler Laura
- Murphy Helen
- Musgrave Hannah
- Mutez Eugénie
- Muñoz Esteban
- Muñoz Juan Marín
- Mächtel Miriam
- Möller Carsten
- Mühlau Mark
- Mühlbäck Alzbeta
- Müller Christoph
- Müller Nicole
- Münchau Alexander
- Münkel Kristina
- Mütze Lisanne
- Nanetti Lorenzo
- Narozańska Ewa
- Neleborn-Lingefjärd Liselotte
- Nemeth Andrea H.
- Nepper Solveig
- Nevitt Louise
- Nielsen Jørgen E.
- Niemelä Valter
- Niess Anke
- Novak Marianne
- Nowak Malgorzata
- Nowak Marielle
- O'Donovan Kirsty
- O'Keefe Deidre
- O'Neill Mari
- Oehmen Martin
- Olivier Audrey
- Ollokainen Mari
- Olofsson Carina
- Oosterloo Mayke
- Opala Grzegorz
- Orth Michael
- Ossig Christiana
- Otti Daniela
- Oughton Emma
- Owen Michael
- Padieu Helene
- Paganini Marco
- Pagonabarraga Javier
- Painold Annamaria
- Palanca Paloma Millan
- Palmer Amy
- Panzeri Marta
- Pardo Sonia Arribas
- Paridi Dominga
- Pariente Jérémie
- Parkinson Andrew
- Partington-Jones Lucy
- Pastor Barbara Vives
- Patel Aakta
- Paterski Laurent
- Patton Michael
- Peacy Caroline
- Pearson Pauline
- Peinemann Alexander
- Peluso Silvio
- Peppa Nadia
- Perea Fuensanta Noguera
- Perez Jesus Perez
- Periañez Juan Manuel
- Peter Mireille
- Petersen Jens A.
- Peterson Maria
- Petersén Åsa
- Petracca Martina
- Petrollini Martina
- Peña José Chacón
- Phillipps Clélie
- Phillips Michelle
- Piacentini Silvia
- Piano Carla
- Pica Emmanuel
- Piedad John
- Pierre Michèle
- Pinter Bernadette
- Playe Alicia
- Plomhause Lucie
- Poda Roberto
- Poewe Werner
- Polo Cecilia Gil
- Porteous Mary
- Pouliquen Dorothée
- Powell Kingsley
- Pradella Silvia
- Price Kathleen
- Prieto Marta Para
- Priller Josef
- Probst Daniela
- Prouzet Julie
- Prundean Adriana
- Prüß Harald
- Pueyo Angel Martínez
- Päivärinta Markku
- Pålhagen Sven
- Quaranta Davide
- Quarrell Oliver
- Rae Daniela
- Rakowicz Maryla
- Raman Ashok
- Ramirez Inés Legarda
- Ramos-Arroyo Maria
- Ramos-Arroyo Maria Antonia
- Raseta Rolland
- Redondo Luis
- Reetz Kathrin
- Reijntjes Robert H. A. M.
- Reilmann Ralf
- Reimer Jan
- Reisinger Karin
- Reiter Eva-Magdalena
- Retterstøl Lars
- Ribacoba René
- Riballo Antonio Villa
- Ribas Guillermo García
- Ribaï Pascale
- Ribbat Michael
- Ribosa Roser
- Richter Przemyslaw
- Rickards Hugh
- Rijntjes Michel
- Rinaldi Carlo
- Rindal Beate
- Ristori Giovanni
- Ritchie Stuart
- Robert Misericordia Floriach
- Robertson Dene
- Robertson Nicola
- Robowski Piotr
- Roca Alessandro
- Roca Elvira
- Rogers Dawn
- Rohm Stefanie
- Rola Rafal
- Rolland Sandrine
- Romano Silvia
- Romero Irene
- Romero Sandra Gutierrez
- Romoli Anna Maria
- Roos Raymund A. C.
- Rose Sarah
- Rosser Anne
- Rosser Elisabeth
- Roth Jan
- Rothery Jean
- Roussel Martine
- Rowett Liz
- Roze Emmanuel
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzińska Monika
- Rummel Jutta
- Rumpf Silke
- Russo Cinzia Valeria
- Ruíz Pedro José García
- Ryglewicz Danuta
- Røren Niini
- Røsby Oddveig
- Sablonnière Bernard
- Saft Carsten
- Salgueiro Ana
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- Sando Sigrid Botne
- Santacruz Pilar
- Santala Maire
- Santhouse Alastair
- Sass Christian
- Savage Lois
- Scaglione Cesa
- Scheibl Monika
- Schepers Sigrun
- Scherer-Gagou Clarisse
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schneider Ariane
- Schoonderbeek Anne
- Schrader Christoph
- Schwenk Daniela
- Schöggl Helmut
- Schüler Béatrice
- Schüpbach Michael
- Sciruicchio Vittorio
- Sebastián Ana Rojo
- Sempołowicz Justyna
- Seppi Klaus
- Serpino Claudia
- Sevilla Maria Ascension Zea
- Sienkiewicz-Jarosz Halina
- Sieradzan Kasia
- Sikiric Alma
- Silva Mark
- Simonelli Maria
- Simonin Clémence
- Simpson Sheila A.
- Sinadinosa Daniela
- Singh Baldev
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Snowden Julie
- Soleti Francesco
- Solito Marcella
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltysiak Beverley
- Solís Pilar
- Sorbi Sandro
- Sorrentino Pierpaolo
- Spadaro Maria
- Spagnolo Francesca
- Spampinato Umberto
- Sprenger Fabienne
- Spruth Eike
- Squitieri Ferdinando
- Staffen Wolfgang
- Stamm Christiane
- Stattin Eva-Lena
- Stebler Yanik
- Steinmetz Gisèle
- Stenwak Agata
- Stokke Bodil
- Stompel Daniel
- Stopford Cheryl
- Storch Alexander
- Stubbe Lars
- Städtler Michael
- Størseth Hanna Haugan
- Stȩpniak Iwona
- Summers Fiona
- Sundblom Jimmy
- Sułek Anna
- Swain Rachel
- Szczudlik Andrzej
- Szczygieł Elzbieta
- Szejko Natalia
- Szinwelski Michal
- Sánchez Vicenta
- Sánchez Violeta Sánchez
- Süssmuth Sigurd
- T Hart Ellen P.
- Tabrizi Sarah
- Tabrizi Sarah J.
- Tacik Pawel
- Tan Louis
- Tard Céline
- Taroni Franco
- Tataru Alina
- Taylor Anne-Marie
- Taylor Cat
- Taylor Rachel
- Tchikviladzé Maya
- Thibault-Tanchou Stéphanie
- Thiel Silvia
- Thomas Gareth
- Thompson Jennifer
- Thompson Jennifer C.
- Thomson Aileen
- Tidswell Katherine
- Timewell Erika
- Timings Leanne
- Tir Mélissa
- Tomasello Chiara
- Tonner Alison
- Torlizzi Flavia
- Torres María Martirio Antequera
- Toscano Jean
- Townhill Jenny
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhard Iris
- Tucci Tecla
- Tuuha Katri
- Tyvoll Hilde
- Udaeta Beatriz
- Uhrova Tereza
- Ulla Miguel
- Ullah Jasmin
- Ure Alexandra
- Valadas Anabela
- Valentine Ruth
- Van Den Bogaard Simon J. A.
- Van Hout Monique S. E.
- Van Oostrom Joost
- Van Paemel Dominique
- Van Vugt Jeroen P. P.
- Van Walsem Marleen
- Van Walsem Marleen R
- Vandenberghe Wim
- Vaughan Vivien
- Ventura Marta Fatás
- Verellen-Dumoulin Christine
- Verhoeven Marloes
- Verny Christophe
- Verstraelen Nichola
- Verstraelen Nicola
- Vezza Maurizio
- Vidal Tiphaine
- Viladrich Cèlia Mareca
- Vilaplana Francisco Castera Brugada Carmen Peiró
- Villa Carolina
- Villanueva Clara
- Villanueva Marina Ávila
- Vivancos Laura
- Vogel Melanie
- Vuillaume Isabelle
- Waber Mirella
- Wagner Caroline
- Wahlström Jan
- Walleczek Anna Maria
- Wannepain Sandrine
- Warner Thomas
- Wasielewska Anna
- Weber Nathalia
- Wehus Ragnhild
- Weindl Adolf
- Wenning Gregor
- Werner Cornelius J.
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Widner Håkan
- Wikström Birgitta
- Wild Edward
- Wild Sue
- Wildson Sébastien Charpentier
- Williams Josh
- Winkelmann Juliane
- Winkler Jürgen
- Witjes-Ané Marie-Noelle
- Witkowski Grzegorz
- Wiśniewski Bartłomiej
- Wolz Annett
- Wolz Martin
- Wood Josh
- Wright Abigail
- Wright Jan
- Wójcik Magdalena
- Yardumian Pam
- Yates Shona
- Youssov Katia
- Zaremba Jacek
- Zaugg Sabine Weber
- Zdzienicka Elzbieta
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Eugeniusz
- Zimmermann Marie-Agathe
- Zinzi Paola
- Ziora-Jakutowicz Karolina
- Zittel Simone
- Zucker Birgit
- Šašinková Pavla
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study