5 research outputs found
Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes
- Author
- Bocchetta M. (Martina)
- Borroni B. (Barbara)
- Butler C.R. (Chris R.)
- Cash D.M. (David M.)
- Convery R.S. (Rhian S.)
- Danek A. (Adrian)
- De Mendonça A. (Alexandre)
- Ducharme S. (Simon)
- Finger E. (Elizabeth)
- Frisoni G.B. (Giovanni B.)
- Galimberti D. (Daniela)
- Gerhard A. (Alex)
- Ghidoni R. (Roberta)
- Graff C. (Caroline)
- Heller C. (Carolin)
- Jones P.S. (P. Simon)
- Kievit R.A. (Rogier A.)
- Kievit R.A. (Rogier A.)
- Laforce R. (Robert)
- Levin J. (Johannes)
- Malpetti M. (Maura)
- Masellis M. (Mario)
- Moore K.M. (Katrina M.)
- Moreno F. (Fermin)
- Otto M. (Markus)
- Peakman G. (Georgia)
- Rittman T. (Timothy)
- Rohrer J.D. (Jonathan)
- Rowe J.B. (James)
- Santana I. (Isabel)
- Sorbi S. (Sandro)
- Swieten J.C. (John) van
- Synofzik M. (Matthis)
- Sánchez-Valle R. (Raquel)
- Tagliavini F. (Fabrizio)
- Tartaglia M.C. (Maria Carmela)
- Todd E.G. (Emily G.)
- Tsvetanov K.A. (Kamen A.)
- Vandenberghe R. (Rik)
- Publication venue
- 'Wiley'
- Publication date
- 03/11/2020
- Field of study
Introduction: Apathy adversely affects prognosis and survival of patients with frontotemporal dementia (FTD). We test whether apathy develops in presymptomatic genetic FTD, and is associated with cognitive decline and brain atrophy. Methods: Presymptomatic carriers of MAPT, GRN or C9orf72 mutations (N = 304), and relatives without mutations (N = 296) underwent clinical assessments and MRI at baseline, and annually for 2 years. Longitudinal changes in apathy, cognition, gray matter volumes, and their relationships were analyzed with latent growth curve modeling. Results: Apathy severity increased over time in presymptomatic carriers, but not in non-carriers. In presymptomatic carriers, baseline apathy predicted cognitive decline over two years, but not vice versa. Apathy progression was associated with baseline low gray matter volume in frontal and cingulate regions. Discussion: Apathy is an early marker of FTD-related changes and predicts a subsequent subclinical deterioration of cognition before dementia onset. Apathy may be a modifiable factor in those at risk of FTD
Age at first birth in women is genetically associated with increased risk of schizophrenia
- Author
- Adolfsson R.
- Agartz I. (Ingrid)
- Agerbo E. (Esben)
- Albus M. (Margot)
- Alexander M. (Madeline)
- Amin F. (Farooq)
- Andreassen O.A. (Ole)
- Bacanu S.A. (Silviu)
- Begemann M. (Martin)
- Belliveau R.A. (Richard A.)
- Bene J. (Judit)
- Bergen S.E. (Sarah)
- Bevilacqua E. (Elizabeth)
- Bigdeli T.B. (Tim B.)
- Black D.W. (Donald)
- Blackwood D.H.R. (Douglas)
- Borglum A.D. (Anders)
- Bramon E. (Elvira)
- Bruggeman R. (Richard)
- Buccola N.G. (Nancy G)
- Buckner M.
- Bulik-Sullivan B.K. (Brendan)
- Buxbaum J.D. (Joseph D.)
- Byerley W.F. (William F)
- Cahn W. (Wiepke)
- Cai G. (Guiqing)
- Campion D. (Dominique)
- Cantor R.M.
- Carr V.J. (Vaughan J.)
- Carrera N. (Noa)
- Catts S.V. (Stanley)
- Chambert K. (Kimberly)
- Chan R.C.K. (Raymond C. K.)
- Chen E.Y.H. (Eric Y. H.)
- Chen R.Y.L. (Ronald Y.)
- Cheng W. (Wei)
- Cheung E.F.C. (Eric F. C.)
- Chong S.A. (Siow Ann)
- Cichon S. (Sven)
- Clair D.S.
- Cloninger C.R. (C Robert)
- Cohen D.J. (David J.)
- Cohen N. (Nadine)
- Collier D.A. (David)
- Cormican P. (Paul)
- Corvin A. (Aiden)
- Craddock N.J. (Nick)
- Crowley J.J. (James)
- Curtis D. (David)
- Daly M.J. (Mark J.)
- Darvasi A. (Ariel)
- Davidson M.W. (Michael )
- Davis K.L. (Kenneth)
- Degenhardt F.
- Del-Favero J. (Jurgen)
- Demontis D. (Ditte)
- Dikeos D. (Dimitris)
- Dinan T. (Timothy)
- Djurovic S. (Srdjan)
- Domenici E. (Enrico)
- Donohoe D.J. (Dennis)
- Drapeau E. (Elodie)
- Duan J. (Jubao)
- Dudbridge F. (Frank)
- Durmishi N. (Naser)
- Ehrenreich H. (Hannelore)
- Eichhammer P. (Peter)
- Escott-Price V. (Valentina)
- Esko T. (Tõnu)
- Essioux L. (Laurent)
- Fanous A.H. (Ayman H.)
- Farh K.-H. (Kai-How)
- Farrell M.S. (Martilias)
- Frank J. (Josef)
- Franke L. (Lude)
- Freedman R. (Robert)
- Freimer N.B. (Nelson)
- Friedl M.
- Friedman J.I. (Joseph)
- Fromer M. (Menachem)
- Gejman P.V. (Pablo)
- Genovese G. (Giulio)
- Georgieva I. (Irina)
- Giegling I. (Ina)
- Gill M. (Michael)
- Giusti-Rodríguez P. (Paola)
- Godard S. (Stephanie)
- Goldstein J.I. (Jacqueline)
- Golimbet V. (Vera)
- Gopal R. (Robin)
- Gratten J. (Jacob)
- Gurling H. (Hugh)
- Haan L. (Lieuwe) de
- Hagen K. (Knut)
- Hammer C. (Christian)
- Hamshere M.L. (Marian)
- Hansen M. (Mark)
- Hansen T. (Thomas)
- Haroutunian V. (Vahram)
- Hartmann A.M. (Annette M.)
- Henskens F.A. (Frans)
- Herms S. (Stefan)
- Hirschhorn J.N. (Joel)
- Hoffmann P. (Per)
- Hofman A. (Andrea)
- Hollegaard M.V. (Mads V)
- Holmans P.A. (Peter A.)
- Hougaard D.M. (David)
- Huang H. (Hailiang)
- Hultman C.M. (Christina)
- Ikeda M. (Masashi)
- Iwata N. (Nakao)
- Jablensky A. (Assen)
- Joa I. (Inge)
- Juliá A. (Antonio)
- Jönsson E.G. (Erik)
- Kahn R. (René)
- Kalaydjieva L. (Luba)
- Karachanak-Yankova S. (Sena)
- Karjalainen J. (Juha)
- Kavanagh D. (David)
- Keller M.C. (Matthew C)
- Kendler K. (K.)
- Kennedy J.L.
- Keong J.L.C. (Jimmy Lee Chee)
- Khrunin A. (Andrey)
- Kim Y. (Yunjung)
- Kirov G. (George)
- Klovins J. (Janis)
- Knight J. (Jo)
- Knowles J.A. (James A)
- Konte B. (Bettina)
- Kucinskiene Z.A. (Zita Ausrele)
- Kuzelova-Ptackova H. (Hana)
- Kučinskas V. (Vaidutis)
- Kähler J. (Jan)
- Laurent C. (Camille)
- Lee P.H. (Phil H.)
- Lee S.H. (Sang Hong)
- Legge S.E. (Sophie)
- Lencz T. (Todd)
- Lerer B. (Bernard)
- Levinson D.F. (Douglas F.)
- Li M. (Miaoxin)
- Li Q.S. (Qingqin S.)
- Li T. (Tao)
- Liang K.-Y. (Kung-Yee)
- Lieberman A.P. (Andrew)
- Limborska S. (Svetlana)
- Liu J. (Jianjun)
- Loughland C.M. (Carmel)
- Lubinski J. (Jan)
- Lönnqvist J. (Jouko)
- Macek M. (Milan MI)
- Magnusson P.K. (Patrik)
- Maher B.S. (Brion)
- Maier W. (Wolfgang)
- Malhotra A.K. (Anil K)
- Mallet V. (Vincent)
- Marsal S. (Sara)
- Mattheisen M. (Manuel)
- Mattingsdal M. (Morten)
- McCarley R.W. (Robert)
- McCarroll S.A. (Steve)
- McDonald C. (Colm)
- McIntosh A.M. (Andrew)
- McQuillin A. (Andrew)
- Meier S.
- Meijer C. (Carin)
- Melegh B. (Bela)
- Melle I. (Ingrid)
- Mesholam-Gately R.I. (Raquelle)
- Metspalu A. (Andres)
- Michie P.T. (Patricia)
- Milani L. (Lili)
- Milanova V. (Vihra)
- Mokrab Y. (Younes)
- Moran J.L. (Jennifer L.)
- Morris D.W. (Derek W.)
- Mors O.
- Mortensen P.B.
- Mowry B.J. (Bryan J)
- Murphy K.C. (Kieran)
- Murray R. (Robin)
- Myin-Germeys I. (Inez)
- Müller-Myhsok B. (B.)
- Neale B.M. (Benjamin)
- Nelis M. (Mari)
- Nenadic I. (Igor)
- Nertney D.A. (Deborah)
- Nestadt G. (Gerald)
- Ni G. (Guiyan)
- Nicodemus K.K. (Kristin)
- Nikitina-Zake L. (Liene)
- Nisenbaum L. (Laura)
- Nordin A. (Annelie)
- Nöthen M.M. (Markus)
- O'Callaghan E. (Eadbhard)
- O'donovan M.C. (Michael)
- O'Dushlaine C. (Colm)
- O'neill F.A. (F. Anthony)
- Oh S.-Y. (Sang-Yun)
- Olincy A. (Ann)
- Olsen L. (Line)
- Ophoff R.A. (Roel)
- Os J.V. (Jim Van)
- Owen M.J. (Michael)
- Palotie A. (Aarno)
- Pantelis C. (Christos)
- Papadimitriou G.N. (George)
- Papiol S. (Sergi)
- Parkhomenko E. (Elena)
- Pato C. (Carlos)
- Pato C. (Carlos)
- Paunio T. (Tiina)
- Pejovic-Milovancevic M. (Milica)
- Perkins D.O. (Diana O.)
- Pers T.H. (Tune)
- Petryshen T.L. (Tracey L.)
- Pietiläinen O.P.H. (Olli)
- Pimm J. (Jonathan)
- Pocklington A.J. (Andrew)
- Posthuma D. (Danielle)
- Powell J. (John)
- Price A. (Alkes)
- Pulver A.E. (Ann)
- Purcell S.M. (Shaun M.)
- Quested D.J. (Digby J)
- Rasmussen H.B. (Henrik B)
- Reichenberg A. (Abraham)
- Reimers B. (Bernhard)
- Richards A. (Alex)
- Rietschel M. (Marcella)
- Riley B.P. (Brien P.)
- Ripke S. (Stephan)
- Roffman J.L. (Joshua)
- Roussos A. (Alexandra)
- Ruderfer D. (Douglas)
- Rujescu D. (Dan)
- Salomaa V. (Veikko)
- Sanders A.R. (Alan)
- Schall J.D. (Jeffrey)
- Schubert C.R. (Christian R.)
- Schulze T.G. (Thomas)
- Schwab S.G. (Sibylle G.)
- Scolnick E. (Edward)
- Scott R.J. (Rodney J.)
- Seidman L.J. (Larry)
- Sham P.C. (Pak C.)
- Shi J. (Jianxin)
- Sigurdsson E. (Engilbert)
- Silagadze T. (Teimuraz)
- Silverman J.M. (Jeremy M.)
- Sim K. (Kang)
- Sklar P. (Pamela)
- Slominsky P. (Petr)
- Smoller J.W.
- So H.-C. (Hon-Cheong)
- Spencer C.C.A. (Chris C.)
- Stahl E.A. (Eli A.)
- Stefansson H. (Hreinn)
- Steinberg S. (Stacy)
- Stogmann E. (Elisabeth)
- Straub R.E. (Richard)
- Strengman E. (Eric)
- Strohmaier J. (Jana)
- Stroup T.S. (T. Scott)
- Subramaniam V. (Venkat)
- Sullivan P.F. (Patrick)
- Suvisaari J. (Jaana)
- Svrakic D.M. (Dragan)
- Szatkiewicz J.P. (Jin P.)
- Söderman E. (Erik)
- Thirumalai S. (Srinivasa)
- Toncheva D. (Draga)
- Tosato S. (Sarah)
- Veijola J. (Juha)
- Visscher P.M. (Peter)
- Waddington J. (John)
- Walsh D. (Dermot)
- Walters J.T. (James)
- Wang D. (Dai)
- Wang Q. (Qiang)
- Webb B.T. (Bradley T.)
- Weinberger D.R. (Daniel)
- Weiser M. (Mark)
- Wendland A. (Annika)
- Werge T.M. (Thomas)
- Wildenauer D.B. (Dieter)
- Williams N.M. (Nigel M.)
- Williams S. (Stephanie)
- Witt S.H. (Stephanie H)
- Wolen A.R. (Aaron)
- Wong E.H.M. (Emily H.M.)
- Wormley B.K. (Brandon K.)
- Wray N.R. (Naomi R.)
- Xi H.S. (Hualin Simon)
- Zai C.C. (Clement C.)
- Zheng X. (Xuebin)
- Zimprich F. (Fritz)
- Zwart J-A. (John-Anker)
- Publication venue
- Publication date
- 01/01/2018
- Field of study
Prof. Paunio on PGC:n jäsenPrevious studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia and AFB in women stratified into younger and older groups. We find evidence for an association between predicted genetic risk of schizophrenia and AFB in women (P-value = 1.12E-05), and we show genetic heterogeneity between younger and older AFB groups (P-value = 3.45E-03). The genetic correlation between schizophrenia and AFB in the younger AFB group is -0.16 (SE = 0.04) while that between schizophrenia and AFB in the older AFB group is 0.14 (SE = 0.08). Our results suggest that early, and perhaps also late, age at first birth in women is associated with increased genetic risk for schizophrenia in the UK Biobank sample. These findings contribute new insights into factors contributing to the complex bio-social risk architecture underpinning the association between parental age and offspring mental health.Peer reviewe
Therapeutic anticoagulation with heparin in noncritically Ill patients with Covid-19
- Author
- Aday Aaron W.
- Al-Beidh Farah
- Angus Derek C.
- Annane Djillali
- Arabi Yaseen M.
- Aryal Diptesh
- Beane Abi
- Berge Jeffrey S.
- Berry Lindsay R.
- Berry Scott M.
- Bhimani Zahra
- Bihari Shailesh
- Billett Henny H.
- Bond Lindsay
- Bonten Marc
- Bradbury Charlotte A.
- Brooks Maria M.
- Brunkhorst Frank
- Buxton Meredith
- Buzgau Adrian
- Carrier Marc
- Castellucci Lana A.
- Chekuri Sweta
- Chen Jen-Ting
- Cheng Allen C.
- Chkhikvadzw Tamta
- Coiffard Benjamin
- Costantini Todd W.
- Cushman Mary
- de Brouwer Sophie
- Derde Lennie P.G.
- Detry Michelle A.
- Duggal Abhijit
- Dzavik Vladimir
- Effron Mark B.
- Escobedo Jorge
- Estcourt Lise J.
- Everett Brendan M.
- Farkouh Michael E.
- Fergusson Dean A.
- Fitzgerald Mark
- Fowler Robert A.
- Galanaud Jean P.
- Galen Benjamin T.
- Gandotra Sheetal
- Garcia-Madrona Sebastian
- Girard Timothy D.
- Godoy Lucas C.
- Golighe Ewan C.
- Gong Michelle N.
- Gonzalez Yessica S. Perez
- Goodman Andrew L.
- Goossens Herman
- Gordon Anthony C.
- Green Cameron
- Greenstein Yonatan Y.
- Gross Peter L.
- Guerreor Raquel Morillo
- Hamburg Naomi M.
- Haniffa Rashan
- Hanna George
- Hanna Nicholas
- Hegde Sheila M.
- Hendrickson Carolyn M.
- Higgins Alisa M.
- Hindenburg Alexander A.
- Hite R. Duncan
- Hochman Judith S.
- Hope Aluko A.
- Horowitz James M.
- Horvat Christopher M.
- Houston Brett L.
- Huang David T.
- Hudock Kristin
- Hunt Beverley J.
- Husain Mansoor
- Hyzy Robert C.
- Iyer Vivek N.
- Jacobson Jeffrey R.
- Jayakumar Devachandran
- Kah Susan R.n
- Keller Norma M.
- Khan Akram
- Kim Keri S.
- Kim Yuri
- Kin Andrew J.
- Kindzelski Andrei L.
- Kirwan Bridget-Anne
- Knudson M. Margaret
- Kornblith Aaron E.
- Kornblith Lucy Z.
- Kreuziger Lisa Baumann
- Krishnan Vidya
- Kumar Anand
- Kutcher Matthew E.
- Laffan Michael A.
- Lamontagne Francois
- Lawler Patrick R.
- Le Gal Gregoire
- Leeper Christine M.
- Leifer Eric S.
- Lewis Roger J.
- Lim George
- Lima Felipe Gallego
- Linstrum Kelsey
- Litton Edward
- Lopez-Sendon Jose
- Lorenzi Elizabeth
- Lother Sylvain A.
- Malhotra Saurabh
- Marcos Miguel
- Marinez Andrea Saud
- Marshall John C.
- Marten Nicole
- Matthay Michael A.
- McArthur Colin J.
- McAuley Daniel F.
- McDonald Emily G.
- McGlothlin Anna
- McGuinness Shay P.
- McQuilten Zoe
- McVerry Bryan J.
- Middeldorp Saskia
- Montgomery Stephanie K.
- Moore Steven C.
- Moreno Jose L. Lopez-Sendon
- Mouncey Paul R.
- Murthy Srinivas
- Nair Girish B.
- Nair Rahul
- Neal Matthew D.
- Nichol Alistair D.
- Nicolau Jose C.
- Nunez-Garcia Brenda
- Pandey Ambarish
- Park Pauline K.
- Parke Rachael L.
- Parker Jane C.
- Parnia Sam
- Paul Jonathan D.
- Pompilio Mauricio
- Prekker Matthew E.
- Quigley John G.
- Reynolds Harmony R.
- Rosenson Robert S.
- Rost Natalia S.
- Rowan Kathryn
- Santos Fernanda O.
- Santos Marlene
- Santos Mayler Olombrada
- Satterwhite Lewis
- Saunders Christina T.
- Schutgens Roger E.G.
- Seymour Christopher W.
- Shankar-Hari Manu
- Sheehan John P.
- Siegal Deborah M.
- Silva Delcio G., Jr.
- Singhal Aneesh B.
- Slutsky Arthur S.
- Solvaso Dayna
- Stanworth Simon J.
- Tritschler Tobias
- Turgeon Alexis F.
- Turner Anne M.
- Van Bentum-Puijk Wilma
- van de Veerdonk Frank L.
- van Diepen Sean
- Vazquez-Grande Gloria
- Wahid Lana
- Wareham Vanessa
- Webb Steven A.
- Wells Bryan J.
- Widmer R. Jay
- Wilson Jennifer G.
- Yuriditsky Eugene
- Zampieri Fernando G.
- Zarychanski Ryan
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Therapeutic anticoagulation with heparin in critically Ill patients with Covid-19
- Author
- Ahuja Tania
- Al-Beidh Farah
- Angus Derek C.
- Annane Djillali
- Arabi Yaseen M.
- Aryal Diptesh
- Beane Abi
- Berger Jeffrey S.
- Berry Lindsay R.
- Berry Scott M.
- Bhimani Zahra
- Bihari Shailesh
- Billett Henny H.
- Bond Lindsay
- Bonten Marc
- Bradbury Charlotte A.
- Brooks Maria M.
- Brunkhorst Frank
- Buxton Meredith
- Buzgau Adrian
- Carrier Marc
- Castellucci Lana A.
- Chekuri Sweta
- Chen Jen-Ting
- Cheng Allen C.
- Chkhikvadze Tamta
- Coiffard Benjamin
- Contreras Aira
- Costantini Todd W.
- Cushman Mary
- de Brouwer Sophie
- Derde Lennie P.G.
- Detry Michelle A.
- Duggal Abhijit
- Dzavik Vladimir
- Effron Mark B.
- Eng Heather F.
- Escobedo Jorge
- Estcourt Lise J.
- Everett Brendan M.
- Farkouh Michael E.
- Fergusson Dean A.
- Fitzgerald Mark
- Fowler Robert A.
- Froess Joshua D.
- Fu Zhuxuan
- Galanaud Jean P.
- Galen Benjamin T.
- Gandotra Sheetal
- Garcia Eduardo Mateos
- Girard Timothy D.
- Godoy Lucas C.
- Goligher Ewan C.
- Gong Michelle N.
- Goodman Andrew L.
- Goossens Herman
- Gordon Anthony C.
- Green Cameron
- Greenstein Yonatan Y.
- Gross Peter L.
- Haniffa Rashan
- Hegde Sheila M.
- Hendrickson Carolyn M.
- Higgins Alisa M.
- Hindenburg Alexander A.
- Hochman Judith S.
- Hope Aluko A.
- Horowitz James M.
- Horvat Christopher M.
- Houston Brett L.
- Huang David T.
- Hudock Kristin
- Hunt Beverley J.
- Husain Mansoor
- Hyzy Robert C.
- Jacobson Jeffrey R.
- Jayakumar Devachandran
- Kahn Susan R.
- Keller Norma M.
- Khan Akram
- Kim Keri S.
- Kim Yuri
- Kindzelski Andrei
- King Andrew J.
- Kirwan Bridget-Anne
- Kornblith Aaron E.
- Kornblith Lucy Z.
- Kreuziger Lisa Baumann
- Kumar Anand
- Kutcher Matthew E.
- Laffan Michael A.
- Lamontagne Francois
- Lawler Patrick R.
- Le Gal Gregoire
- Leeper Christine M.
- Leifer Eric S.
- Lewis Roger J.
- Lim George
- Lima Felipe Gallego
- Linstrum Kelsey
- Litton Edward
- Lopez-Sendon Jose
- Lorenzi Elizabeth
- Lother Sylvain A.
- Marinez Andrea Saud
- Marshall John C.
- Marten Nicole
- Martinez Mary
- Mavromichalis Stavroula
- McArthur Colin J.
- McAuley Daniel F.
- McDonald Emily G.
- McGlothlin Anna
- McGuinness Shay P.
- McQuilten Zoe
- McVerry Bryan J.
- Middeldorp Saskia
- Montgomery Stephanie K.
- Mouncey Paul R.
- Murthy Srinivas
- Nair Girish B.
- Nair Rahul
- Neal Matthew D.
- Nichol Alistair D.
- Nicolau Jose C.
- Nunez-Garcia Brenda
- Park John J.
- Park Pauline K.
- Parke Rachael L.
- Parker Jane C.
- Parnia Sam
- Paul Jonathan D.
- Pompilio Mauricio
- Quigley John G.
- Reynolds Harmony R.
- Rosenson Robert S.
- Rost Natalia S.
- Rowan Kathryn
- Santos Fernanda O.
- Santos Marlene
- Santos Mayler O.
- Satterwhite Lewis
- Saunders Christina T.
- Schreiber Jake
- Schutgens Roger E.G.
- Seymour Christopher W.
- Siegal Deborah M.
- Silva Delcio G.
- Singhal Aneesh B.
- Slutsky Arthur S.
- Solvason Dayna
- Tritschler Tobias
- Turgeon Alexis F.
- Turner Anne M.
- Van Bentum-Puijk Wilma
- van de Veerdonk Frank L.
- van Diepen Sean
- Vazquez-Grande Gloria
- Wahid Lana
- Wareham Vanessa
- Webb Steven A.
- Widmer R. Jay
- Wilson Jennifer G.
- Yuriditsky Eugene
- Zarychanski Ryan
- Zhong Yongqi
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Whole-genome sequencing reveals host factors underlying critical COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdelrazik Marwa
- Abdollahi Hamed
- Abdullah T.
- Abecasis Goncalo
- Abedalthagafi M.
- Abel Lynn
- Abernathy C.
- Abraheem Azmeralde
- Abul-Husn Noura S.
- Acquilini D.
- Adams C.
- Adams Emma L.
- Adams K.
- Adamsara Alireza
- Adanini Olurenke
- Adeleye O.
- Adra D.
- Afilalo J.
- Afilalo M.
- Afolabi D.
- Afrasiabi Z.
- Agasou A.
- Agrawal Shruti
- Agüero D.
- Ahmad N.
- Ahmadi Saeideh
- Ahmed A.
- Ahmed Cecilia
- Akeroyd L.
- Akhtar M.N.
- Akinkugbe O.
- Aksentijevich Alexandra
- Al-Afghani H.
- Al-Awdah L.
- Alaamery M.
- Alahmadey Z.Z.
- Alaverdian D.
- Alavere H.
- Albader A.
- Albaiceta G.M.
- Albakri J.K.
- AlBardis H.
- Albeladi M.
- Albesher N.
- Albrich W.
- AlDhawi N.
- Aldridge J.
- Aleagha Afshar Etemadi
- Alexander Peter.
- Alfonso J.
- Alghamdi B.
- Alghamdi J.
- Ali A.
- Ali Altaf
- Ali I.A.M.
- Ali Syamlan
- Aliannejad Rasoul
- Aljawini N.
- AlJohani S.
- Alkwai S.
- Allan A.
- Allan E.
- Allan J.
- Alldis Zoe
- Allen L.
- Allen Meryem
- Allen Schvearn
- Allibone S.
- Allison K.S.
- Allos R.
- Ally S.M.
- AlMalik A.
- Almalki F.
- Almohammed I.
- Almutairi M.
- Alotaibi S.
- Alowayn A.M.
- Alqahtani S.
- Alqubaishi F.
- Alrashed M.
- Alshareef A.
- Alsolm E.
- Alswailm M.
- Altabaibeh A.
- Alvaro A.
- AlZahrani D.
- Amin V.
- Amirsavadkouhi Ali
- Amitrano Sara
- Anastasescu E.
- Anderson F.
- Anderson J.
- Anderson Madeleine
- Anderson Peter
- Anderson S.
- Anderson S.
- Anderson T.
- Andolfo I.
- Andretta F.
- Andreucci E.
- Andrew Angela
- Andrew B.
- Andrew Gratrix
- Andrews E.
- Andrews Shea J.
- Anedda F.
- Anemoli V.
- Annis A.
- Antcliffe David
- Antinori Andrea
- Antoni M.D.
- Anumakonda V.
- Apetri E.
- Aquino Maia
- Arabi Y.M.
- Aravindan Latha
- Arbane Gill
- Archer Katie
- Arden T.
- Arias Sonia Sousa
- Arif S.
- Armstrong Jacob
- Armstrong Lisa
- Armstrong Ruth
- Arning N.
- Arnold Sophie
- Arranz María Jesús
- Arribas E.
- Artuso R.
- Arumugam Prabhu
- Ascolillo Steven
- Ashraf Saima
- Ashton L.
- Aslibekyan S.
- Astin-Chamberlain Raine
- Atkinson E.G.
- Attwood B.
- Aucella F.
- Auld D.
- Auld F.
- Austin Karen
- Austin Pauline
- Auton A.
- Ayers A.
- Azarzar S.
- Bachetti T.
- Baikady R.R.
- Baillie John Kenneth
- Baines Balvinder
- Baines D.
- Baines K.
- Baird Yolanda
- Bakthavatsalam Dhanalakshmi
- Balaconis Mary K.
- Baldassarri M.
- Ball C.A.
- Baltzell A.H.
- Bamford A.
- Bamford Peter
- Banach Dorota
- Bancroft Hollie
- Band G.
- Bandini M.
- Bandla Nageswar
- Bano S.
- Baptista David
- Barakeh D.
- Baras Aris
- Baratti S.
- Barber R.
- Barberis L.
- Barbieri C.
- Barclay Lucy
- Bargagli E.
- Barhoush E.
- Barker J.
- Barnes K.C.
- Baroni S.
- Barrett F.
- Barron A.
- Barry P.
- Bartels M.
- Bartley Shauna
- Baruah R.
- Bashyal Archana
- Basikolo C.
- Bassetti M.
- Bastion V.
- Bates H.
- Bates Michelle
- Batini Chiara
- Battle Ceri
- Bauchmuller K.
- Baxter N.
- Baya N.
- Bayo L.A.
- Beadle Jane
- Bean S.
- Beaumont K.
- Beavis S.
- Beck A.
- Beckmann Noam D.
- Bedini J. L.
- Bee Catherine E.
- Beech E.
- Beech Valerie
- Beekes M.
- Beesley K.
- Begg Colin
- Beguin Y.
- Behan T.
- Beith C.M.
- Belagodu Zakaula
- Belbin Gillian Morven
- Belfield H.
- Belhaj Y.
- Beligni G.
- Belisle A.
- Bell D.
- Bell G.
- Bell M.
- Bell S.
- Bellamy Mary
- Belli M.A.
- Bellini A.
- Bellwood R.
- Below Jennifer
- Bemand T.
- Benetti E.
- Benham Leonie
- Bennett D.
- Bennett Sara
- Bentley David
- Bentley M.
- Benyon S.
- Beranova E.
- Bercades G.
- Bergantini L.
- Bergomi P.
- Berkowitz Nathan
- Bernardo D.
- Bevan E.
- Bewley J.
- Bhatia Nikhil
- Bhatterjee Ravi
- Bhuie Parminder
- Bi R.
- Biagio A.D.
- Bianchi F.
- Bibert S.
- Bibi Fatima
- Biddle Jack
- Biggs Heather
- Birch J.
- Birch J.
- Birch Sophie.
- Birchall K.
- Birchall K.
- Bird S.
- Birkinshaw Isobel
- Birt M.
- Biscarini F.
- Black E.
- Black K.
- Blackledge B.
- Blackman H.
- Blakemore H.
- Blay Natalia
- Blow Sara
- Blunt M.
- Board S.
- Bochud P.Y.
- Bociek Aneta
- Boezen M.
- Boillat N.
- Bokhari M.
- Bolton Matthew
- Bolton Rachel
- Bonner Stephen
- Booker L.
- Borislavova B.
- Borra Catherine
- Botello A.
- Botfield Liam
- Bottà G.
- Bouab M.
- Bough L.
- Boughton A.P.
- Bowes A.
- Bowles Ruth
- Boyle P.
- Boyle R.
- Boz Ceilia
- Bradford Y.
- Bradley C.
- Bradley P.
- Bradley-Potts Joanne
- Bradshaw Zena
- Brady A.
- Brady M.
- Brady R.
- Brandwood C.
- Branney D.
- Brantwood Craig
- Brassard N.
- Brayne A.
- Brealey D.
- Bremmer P.
- Brenner B.
- Bretherick Andrew D.
- Brett Michael
- Brett Stephen
- Brickell K.
- Bridgett V.
- Brimfield Lutece
- Brinkworth Elaine
- Briton Kate
- Britvan Bari
- Bromley M.
- Brooke Hollie
- Brooks S.
- Brown A.
- Brown Adam
- Brown C.W.
- Brown Ellen
- Brown Joanna
- Bruce M.
- Brumpton Ben M.
- Bruno Raffaele
- Brunton Mark
- Bruttini M.
- Bryant J.
- Bryant S.
- Buckley C.
- Buckley Sarah
- Bunni L.
- Burda D.
- Buring Julie E
- Burn I.
- Burnett C.
- Burns K.
- Burt K.
- Burtenshaw Andrew
- Burton Maudrian
- Busani S.
- Bussotti M.
- Butcher D.
- Butler Aaron
- Butler Joanna
- Butler S.
- Butler-Laporte G.
- Butterworth A.S.
- Butterworth-Cowin N.
- Button H.
- Buxbaum Joseph D
- Cabrelli Louise
- Cagova L.
- Caldarelli G.P.
- Callaghan Marie
- Callier S.
- Cameli Paolo
- Campbell Archie
- Campbell Archie
- Campbell Helen
- Campbell Rachael
- Campbell Suzanne
- Campos Sara
- Camsooksai J.
- Canaccini A.
- Cantarini L.
- Cantor M.N.
- Capasso M.
- Capitani K.
- Cappelli S.
- Capps N.
- Carbral-Ortega L.
- Carella M.
- Carey D.J.
- Carmody Margaret
- Carmody S.
- Carnahan M.
- Carreras A.
- Carriero M.L.
- Carter A.
- Carter David
- Carter E.
- Carter Joseph
- Carter S.
- Carungcong J.
- Casey Matt
- Castaño-Vinyals G.
- Castelli F.
- Castle K.
- Castori M.
- Caswell Melanie
- Catena E.
- Caterson Jess
- Cathcart Susanne
- Catlow L.
- Caulfield Mark J.
- Cavazza Anna
- Cawley Kathryn
- Cawthron K.
- Ceri S.
- Chablani M.
- Chadbourn Indra
- Chamnanphon Monpat
- Chan Georgia
- Chan R.
- Chandler B.
- Chang Xiao
- Chapman Susan
- Chariyavilaskul Pajaree
- Charles B.
- Charlesworth Ruth
- Charney Alexander W.
- Charnock R.
- Chasman D.I.
- Chassé M.
- Chaudhary Kumardeep
- Chavan S.
- Cheema Yusuf
- Chen Hung-Hsin
- Chen Jiantao
- Cheng N.
- Cherian Shiney
- Chetam L.
- Chetruengchai Wanna
- Cheyne C.
- Childs D.
- Chittoor G.
- Cho Judy H.
- Cho K.
- Choi Sam
- Choudhury Yasmin
- Christine Almaden-Boyle None
- Chukkambotla Srikanth
- Churchhouse C.
- Chwialkowska Karolina
- Claassen S.
- Clamp Sarah
- Clapham M.
- Claringbould A.
- Clark Amy
- Clark M.
- Clark Martynn
- Clark Richard
- Clark Sarah
- Clark Victoria
- Clarke D.
- Clarke N.
- Clarkson M.
- Clayton Sarah
- Clement Ian
- Clements S.
- Coates Charlotte
- Cockrell Maeve
- Coetzee S.
- Coghlan Phoebe
- Coignet M.
- Coiro G.
- Coker D.
- Cole J.
- Cole J.
- Cole Stephen
- Coleman Dabheoc
- Coles Holly
- Colley Julie
- Collier D.
- Collier David
- Collins Amy
- Collins Brett L.
- Collins C.
- Collins E.
- Collins E.
- Collins Katy
- Collins Rebecca
- Collis M.
- Colobrán R.
- Colombo R.
- Combes Edward
- Connolly K.
- Conticini E.
- Convery K.
- Conyngham J.A.
- Cooper J.
- Cooper L.
- Corcoran Eleanor
- Cordioli Mattia
- Cornell S.
- Corral M.A.
- Corridi M.
- Cortés B.
- Cosgrove D.
- Cosier T.
- Cossarizza A.
- Cother Naiara
- Coto E.
- Coton Z.
- Coulding Martina
- Coutts Audrey
- Coventry T.
- Coviello D.A.
- Cowley A.
- Cowley Nicholas
- Cowton Amanda
- Cox Amber
- Coyle Judy
- Craig J.
- Crawley R.
- Creagh-Brown B.
- Crew A.
- Crickmore V.
- Crisp N.
- Criste Kristine
- Cristiano D.
- Croci L.
- Croci S.
- Croft Maria
- Crook D.W.
- Crooks K.
- Crotti L.
- Crowe Rebecca
- Crowley Maria
- Cruz C.
- Cullell Natalia
- Cullum Louise
- Cunningham A.
- Cunningham M.
- Cupitt Jason
- Curgenven H.
- Cusack Rebecca
- Cusick C.
- Cutler Sean
- Cárcel-Márquez Jara
- D'Alessandro M.
- D'Mellow Kenton
- D'Sylva S.
- Da Gloria Edna Fernandes
- Daga S.
- Daglish Jacqueline
- Dale K.
- Dale S.
- Dalmau D.
- Daly Mark J.
- Daly Zoe
- Dalziel Jack
- Dance A.
- Danesh J.
- Daniel A.
- Daniel Priya
- Daniels A.
- Darcis G.
- Dark P.
- Darlington K.
- Das Mihaela
- Das Sukamal
- Dasgin Jo
- Daubney Esther
- Davey Miriam
- David B.
- Davidson Neil
- Davies C.
- Davies E.
- Davies F.
- Davies G.
- Davies K.
- Davies L.
- Davies Michelle
- Davies R.
- Davis Caroline
- Davison Chloe
- Dawson Deborah
- Dawson J.
- Day Nicky
- Daya M.
- de Almeida Martins L.G.
- de Cid R.
- de Geus E.
- de Gordoa Laura Ortiz-Ruiz
- de la Cal-Sabater P.
- De Neef M.
- De Vivo O.
- Deacon Bethan
- Dearden Joy
- Death Y.
- Debreceni G.
- DeDiego M.L.
- Deelen P.
- Deery J.
- Dei S.
- Delgado Carlos Castro
- Demetriou C.
- Denmade C.
- Dennis C.
- Dent K.
- Dent Martin
- Depante Maria
- Desanctis E.
- Dexter Catherine
- Di Angelantonio Emanuele
- Di Domenico P.
- Di Pietro M.
- Dietl Beatriz
- Digby Brian
- Digby Stephen
- Ding Lijun
- Djeugam B.
- Do Ron
- Dobaño C.
- Doble P.
- Dobson Emma
- Doddato G.
- Dodds Steve
- Domingo C.
- Domínguez-Mayoral A.
- Donaldson A.
- Donaldson D.
- Donati A.
- Donlon S.
- Donnachie J.
- Donne B.
- Donnelly K.
- Donnelly Lorna
- Donner K.
- Donnison P.
- Donovan Sally
- Dooks E.
- Doonan R.
- Dore R.
- Dormand N.
- Douglas K.
- Downes Charlotte
- Drummond Andy
- Duberly Stephen
- Duffield Joseph
- Duffin D.
- Duffy Katharine
- Duffy Stacey
- Duncan E.
- Duncan Esther
- Duncan T.
- Dunmore Charlie
- Durand M.
- Durga L.
- Durie Alison
- Durrans L.J.
- Durrant Georgia
- Duskova M.
- Dykes Joseph
- Eapen B.
- Earle S.G.
- Eastgate-Jackson C.
- Easthope Amy
- Easton J.
- Ebano Patrizia
- Eckbad C.
- Edmond I.
- Edwards M.
- Efford G.
- Egan Jasmine
- Eid Mohammed A.
- El-Jawhari Jehan J.
- El-Lawaty Walaa M.
- El-shanshory Mohamed R.
- El-Sherbiny Yasser M.
- Elgar Greg
- Elhadidy Tamer A.
- Elhassan Munzir
- Elliott K.
- Elliott Katherine S.
- Elliott Paul
- Ellis Hannah
- Elnagdy Marwa H.
- Elsaadany M.
- Elston Kay
- Eltayeb A.
- Eltoukhy Madonna M.
- Emiliozzi A.
- English K.
- Erard V.
- Esko T.
- Esparza-Gordillo J.
- Evitts J.
- Ezeobu Obiageri
- Fabbiani M.
- Fagan Andrew
- Falcone M.
- Fallerini C.
- Farnell-Ward Sarah
- Farquhar F.
- Farré X.
- Farzad Z.
- Faulkner B.
- Faulkner Maria
- Fava F.
- Fawkes Angie
- Fawns-Ritchie Chloe
- Fawzy M.S.
- Fearby M.
- Felemban W.A.
- Felton Timothy
- Feng Y.C.A.
- Ferguson S.
- Feri M.
- Fernandes K.
- Fernandes Rita
- Fernandez Ziortza
- Fernandez-Cadenas Israel
- Fernandez-Roman Jaime
- Ferreira Manuel A.R.
- Ferri C.
- Fidler K.
- Filipe H.
- Filshtein-Sonmez T.
- Finch C.
- Findlay L.
- Fine Christopher
- Finer S.
- Finernan Paul
- Finn J.
- Finn S.
- Finney Clare
- Finucane H.
- Fiorentino G.
- Fisher Emma
- Fiz-López A.
- Flanagan R.
- Fletcher Jo
- Flint N.
- Fofano A.
- Folkes Linda
- Foote D.
- Ford A.
- Forgetta V.
- Forsey M.
- Foster L.
- Fotiadis Stavros
- Fottrell-Gould D.
- Fourman Max Head
- Fowler S.
- Fowler T.
- Fowler Tom A.
- Fox C.
- Fox Heather
- Fox Jonathan
- Franchi F.
- Francisci D.
- Franco G.
- Franke George
- Franke L.
- Frankham J.
- Frater Alasdair
- Frediani B.
- Free Robert C.
- Frippiat F.
- Frise Matthew
- Frithiof R.
- Frost Victoria
- Frullanti E.
- Fuller Bridget
- Furini S.
- Furlong Anita
- Furniss James
- Gabbi C.
- Gabrieli A.
- Gaddis Michael
- Gales A.
- Gallagher Bernadette
- Galván-Femenía I.
- Ganesan Arunkumar
- Ganna Andrea
- Garcia S.M.
- Garcia-Aymerich Judith
- García-Clemente M.
- García-Madrona S.
- Gardner Amy
- Garg Atul
- Garland Z.
- Garner L.
- Garrioch S.
- Gascoyne R.
- Gass M.C.
- Gatti F.
- Gay Bethan
- Gaylard J.
- Gaziano J.M.
- Geary T.
- Gellamucho Minnie
- Gemmell Lisa
- Gendall E.
- Genetu R.
- George Aparna
- George L.
- Georges M.
- Gettler Kyle
- Gherman Anca
- Ghosh A.
- Ghosh B.
- Giannattasio F.
- Gibson Sian
- Gignoux C.R.
- Gilbert K.
- Gilchrist Tammy
- Giliberti A.
- Gill Jaspret
- Gill M.
- Giorli A.
- Giot J.B.
- Girach Rumanah
- Girardis M.
- Girshick A.
- Glasgow Susannah.
- Glass L.
- Gledhill L.
- Glessner J.R.
- Glessner Joseph T.
- Goddard Peter
- Goddard Wendy
- Goff E.
- Gofflot S.
- Golden David
- Golder Kim
- Golding Hannah
- Goldstein J.I.
- Golightly Alisa
- Gomez J.
- Gomez Rachel
- Gondo P.
- González-Villa E.
- Goodchild Drew
- Goodsell J.
- Goodwin Emma
- Gopal S.
- Gordon Anthony
- Gordon E.
- Gori Marco
- Gorman C.
- Graham C.
- Grassi D.
- Gratrix A.
- Grau Neus
- Grauslyte Lina
- Green J.
- Green R.C.
- Greer Sandra
- Gregory J.
- Greig J.
- Griffin D.
- Griffiths C.J.
- Griffiths Fiona
- Grimmer L.
- Grip J.
- Guarnaccia A.
- Gude Estefania Treus
- Guerin J.
- Guerrini S.
- Guidelli L.
- Guindo-Martinez M.
- Guiot J.
- Gulati A.
- Gumbrill B.
- Gummadi M.
- Guntz J.
- Gupta A.
- Gupta R.
- Gurasashvili Jana
- Gurr L.
- Guturu H.
- Guyatt Anna L.
- Guzman C.
- Hadebe B.
- Hafezi Katarzyna
- Hairsine B.
- Hakonarson H.
- Halawani R.T.
- Haldeos Anne
- Hales D.
- Halkes M.
- Hall K.
- Halls Rosslyn
- Hambrook G.
- Hamilton David O.
- Hamilton Debbie
- Hammerton K.
- Hanley S.
- Hanratty H.
- Hanson H.
- Hanson K.
- Hansson Karen
- Haq Risna
- Hard K.
- Harden L.
- Harding P.
- Hardy J.
- Harerimana Nadia V.
- Harford Rachel
- Hargreaves Jeanette
- Harling Rhiannan
- Harper R.
- Harrington K.
- Harris C.
- Harris J.
- Harris J.R.
- Harris N.
- Harrison Abiola
- Harrison Alison
- Harrison L.
- Harrison W.
- Harthi F.A.
- Hartley Janice
- Hartridge Pippa
- Harvey A.
- Hasanato R.
- Hass I.
- Hatton J.
- Hawcutt D.
- Hawes J.
- Hay A.
- Hayes Anne
- Hayes K.
- Hayman Mel
- Hays C.
- Hayward Caroline
- Hazelton T.
- Headlam Evie
- Heeney E.
- Hegazy Mohamed A.F.
- Helgeland Ø.
- Hellen Mybaya
- Helm David
- Henderson S.
- Hendry Ross
- Hendry Sara Clohisey
- Henry D.
- Hensen K.
- Herdman-Grant Rosaleen
- Heron Anne Emma
- Hesseldon L.
- Hewitt C.
- Hey S.
- Hibbert M.
- Hierons S.
- Hiester Liam L.
- Higham A.
- Highgate J.
- Hijazi Muhammad
- Hill H.
- Hill M.
- Hilldrith A.
- Hilltout P.
- Hilton Mary
- Hindale J.
- Hinds Charles
- Hirankarn Nattiya
- Ho Y.L.
- Hobden Gillian
- Hobrok M.
- Hodgkiss T.
- Hodgson Luke
- Hoggart Clive
- Holcombe H.
- Holding Kathleen
- Holdroyd K.
- Holland M.
- Hollox Edward J.
- Home M.
- Hong E.L.
- Hope Dave
- Hope S.
- Hopkins Bridget
- Horby Peter
- Hormis A.
- Horner D.
- Hornsby James
- Horowitz Julie E.
- Horsley E.
- Hosseini Abdolmajid
- Hottenga J.J.
- Houlden H.
- Housley K.
- Houston G.
- Howard Kate
- Howe Gwenllian Sera
- Howie L.
- Howle R.
- Howlett A.
- Hruska M.
- Huang Q.Q.
- Huckins Laura M.
- Hudig L.
- Hudson A.
- Huffman J.E.
- Hughes Alistair
- Hughes G.
- Hughes R.A.
- Hugill Keith
- Hull R.
- Hulme Jonathan
- Hultström M.
- Humphrey C.
- Humphreys S.
- Hunt J.
- Hunt Jodie
- Hunt K.A.
- Hurford F.
- Hurt William James
- Hussain Musarat
- Hussain Samia
- Hussain Y.
- Hutter J.
- Hutton Paula
- Huynen P.
- Hveem K.
- Iglesias L.L.
- Ikram M.A.
- Imeson-Wood J.
- Ingham Joanne
- Inweregbu K.
- Iolascon A.
- Ireland Jane
- Irvine V.
- Ishaq T.
- Itan Yuval
- Jackson Matthew
- Jackson P.
- Jackson Y.
- Jackson-Lawrence K.
- Jacob R.
- Jacques J.
- Jacques Nicola
- Jakkula S.
- Jantarabenjakul Watsamon
- Jardine C.
- Jarmain J.
- Jarman C.
- Javaid A.
- Jeffrey Helen
- Jenkins S.
- Jenkins Samuel
- Jennings C.
- Jerome Ellen
- Jetha C.
- Jha Rajeev
- Jhanji S.
- Jim R.
- Jiménez-Xarrié Elena
- Joe W.
- Joefield Teishel
- John Catherine
- Johnson Emily
- Johnson Laura
- Johnson R.
- Johnston Brian
- Jones C.
- Jones D.
- Jones G.A.L.
- Jones J.
- Jones Jessica
- Jones Megan
- Jones Oliver
- Jones Rhianna
- Jones S.
- Jones Tim Owen
- Jordan Daniel
- Jose S.
- Joseph Anna
- Joseph Rosane
- Joseph Sibet
- Josyula N.S.
- Joy Rosie
- Jude Edward
- Jung J.
- Justice Anne
- Kadiri Salma
- Kaliappan A.
- Kallaste A.
- Kallon Delordson
- Kamdar D.
- Kamundi Charlotte
- Kanai Masahiro
- Kannan T.
- Kanu Rebecca
- Kapoor R.
- Karczewski K.J.
- Karjalainen Juha
- Karlson E.W.
- Karp Avromie
- Karthik K.
- Kasipandian V.
- Kassam Jamila
- Katary A.
- Kaufmann D.E.
- Kaul S.
- Kaunisto M.
- Kausar R.
- Kay Andrea
- Kayani A.
- Kaye C.
- Kaye D.
- Kazi Aayesha
- Keating Liza
- Keating Sean
- Keenan N.
- Keenan S.
- Keith Sara
- Keller Katherine
- Kelly D.
- Kelly F.
- Kelly S.
- Kelsall Olivia
- Kennard-Holden G.
- Kennedy-Hay S.
- Kenny Eimear E.
- Kent Alisa
- Kent H.
- Kent Melanie
- Kerr Shona M.
- Keshet-Price J.
- Khade Reena
- Khafaga Walid T.
- Khaliq Waqas
- Khan Meherunnisa
- Khattab A.K.
- Khera Jacyntha
- Kibutu F.
- Kimchi N.
- Kinch Ashley
- King B.
- King D.
- King Kirsten
- King Laura
- Kingsley Clare
- Kirkby A.
- Kisand K.
- Kitson R.
- Kivinen K.
- Klaric Lucija
- Knight A.
- Knight Julian
- Knight S.
- Knighton Abigail
- Knights E.
- Knowles K.
- Koelling N.
- Kogevinas M.
- Kolakaluri L.
- Kong T.
- Koskelainen S.
- Kosmicki Jack A.
- Kousathanas Athanasios
- Krishnamurthy Vinodh
- Kristiansson K.
- Kubisz-Pudelko A.
- Kumar Rita
- Kumar Rohit
- Kumar S.
- Kuravi Aditya
- Laane E.
- Labkowsky Alexander
- Laha S.
- Laisk T.
- Lake V.
- Lamb T.
- Lambermont B.
- Lamond Zoe
- Lancaster N.
- Lancoma-Malcolm Ivone
- Langley Margaret
- Langton H.
- Lankester L.
- Lanting P.
- Latham S.
- Lathrop G.M.
- Latif M.
- Laurent L.
- Law Andy
- Law Dawn
- Law Rachel
- Law Sarah
- Lawton T.
- Lazo Maria
- Leader J.B.
- Lean R.
- Leaver Susannah
- Ledgard C.
- Lee E.
- Lee Paul H.
- Lee S.
- Lee Y.
- LeFaive J.
- Leggett Samantha
- Leigh M.
- Lena F.
- Lenagh B.
- Lennon L.
- Lepage P.
- Lepamets M.
- Levy Tess
- Lewis A.
- Lewis J.
- Lewis T.
- Li B.
- Li K.W.
- Li R.
- Liao Rachel G.
- Liderth S.
- Lidstone-Scott Rebecca
- Liew J.
- Liggett Steven
- Lim Lai
- Lim Rosario
- Lin S.K.
- Lindergard G.
- Ling Lowell
- Linnett V.
- Lipcsey M.
- Lisboa Ana
- Lista M.
- Little J.
- Liyanage K.
- Llucià-Carol Laia
- Loader D.
- Lomas D.
- London Emily
- Long Kate
- Loos Ruth J. F
- Loosley R.
- Lopera E.
- Lorubbio M.
- Lorusso R.
- Love N.
- Loveridge Adam
- Low Emma
- Lozano F.
- Lu W.
- Lubimbi G.
- Lucas A.
- Lucas R.
- Luchi S.
- Ludovisi S.
- Lye A.
- Lyle Amanda
- Lynch Ceri
- Lyon A.
- Lyons C.
- Lyons Marc
- Läll K.
- Léonar P.
- Ma L.
- Mac A.
- Maccacari Elena
- MacCallum N.
- Macgillivray Louise
- MacGoey Patrick
- Macharia I.
- Mackay C.
- Mackintosh K.
- Maclean Alan
- MacMahon M.
- Maggiolo F.
- Magnus P.
- Maharajh A.
- Mahay K.
- Mahenthran M.
- Mahjoob P.
- Mahmoud E.S.
- Mal Hanning
- Malaise O.
- Male Michelle
- Maleady-Crowe Fiona
- Malinauskas Tomas
- Mallinson J.
- Mallon Lewis
- Mamlouk N.
- Mancarella S.
- Mandalà M.
- Mangino M.
- Mangul S.
- Manna Soumendu
- Manso K.
- Manson J.A.E.
- Mantovani S.
- Mapfunde I.
- Maqsood Zahira
- Marani Martyna
- Marcantonio S.
- Marciano C.
- Margalef Jordi
- Margarson Michael
- Mari F.
- Maricic T.
- Marotti Martina
- Marriott C.
- Marriott S.
- Marsden T.
- Marsh C.
- Marsh S.
- Marshall Lucy
- Marshall R.
- Martin A.R.
- Martin D.
- Martin H.C.
- Martin J.
- Martin T.
- Martindale Tim
- Martinelli E.
- Martinez Maria Lopez
- Martinson V.
- Martir G.
- Martí-Fàbregas Joan
- Martín-Nalda A.
- Martínez A.P.
- Mascarenhas M.
- Masjuan J.
- Maslove David
- Mason D.
- Massadeh S.
- Masucci L.
- Masuko S.
- Masunda B.
- Matapure L.
- Matharu Maninderpal
- Matheson J.
- Mathew B.
- Mathew Jisha
- Matt Roseanna
- Matthews J.
- May Peter
- Mayangao I.
- Mayer A.
- Maynard V.
- Mazzei M.A.
- McAlindon Michael
- McAuley Danny
- McCafferty Sarah
- McCormack L.
- McCormick Jacqueline
- McCormick Joseph B.
- McCormick W.
- McCreath G.
- McCulloch Corrienne
- McCurdy Alex
- McCurdy S.
- McFarland D.
- McGowan J.
- McGregor A.
- McGregor A.
- McGuigan P.J.
- McGuinness H.
- McHugh T.
- McIvor S.
- McKechnie Stuart
- McKenley India
- McKenna E.
- McLaughlan D.
- McMaster Ellie
- McMorrow L.
- McNeela Fiona
- McParland C.
- McParland C.
- McPhail Mark
- Meadows Emma
- Meaney Eoghan
- Medhora J.
- Medina-Gomez C.
- Meghari H.
- Meigs J.B.
- Meikle A.
- Meikle Jen
- Melia D.
- Melling Sarah
- Mellor S.
- Meloni I.
- Melville Julie
- Menatti E.
- Mencarelli M.A.
- Menzies D.
- Menéndez-Valladares P.
- Mepham S.
- Mercader J.
- Mercader J.M.
- Mercer Oliver
- Mercer P.
- Meredith Megan
- Merla G.
- Merwaha E.
- Metcalfe Alexandra
- Metherell S.
- Metsalu K.
- Metspalu A.
- Meuris C.
- Mew L.
- Michael A.
- Michael H.T.
- Michalak-Glinska N.
- Middleton H.
- Milani L.
- Millar Jonathan
- Millar Jonathan E.
- Millen G.
- Milligan B.
- Mills G.H.
- Millward H.
- Milner L.
- Mimbrera A.d.F.
- Miraglia F.G.
- Mirshahi Tooraj
- Misset B.
- Mitchard S.
- Mitchell A.M.
- Mitchelmore Oliver
- Mitra A.
- Moahmed Hanteera S.
- Moghaddam Seyed Behrooz Mohseni
- Mohamed Attia A.S.
- Moncur E.
- Mondelli M.U.
- Monforte A.D.
- Monica M.D.
- Monnery Sonja
- Montagnani F.
- Montaser R.
- Montgomery Hugh
- Moore Faye
- Moore L.S.P.
- Moore Shona C.
- Mooser V.
- Moreno V.
- Moreno-Cuesta Jeronimo
- Morgan Aled
- Morgan J.
- Morino Eriko
- Morrice Kirstie
- Morris A.
- Morris Lucy
- Morris Marcela
- Morris S.
- Morrison A.
- Morrison D.R.
- Moss Stuart
- Mostoles L.
- Motherwell N.
- Moultrie S.
- Moutschen M.
- Moutsianas Loukas
- Msiska Maines
- Mtuwa S.
- Muchenje N.
- Muiño Elena
- Mulcahy Michelle
- Mulla Suleman.
- Mullan D.
- Munt Sheila
- Mupudzi M.
- Murdoch E.
- Murdoch S.
- Murphy A.
- Murphy Carl
- Murphy L.
- Murphy Lee
- Murphy S.N.
- Murphy Sheena
- Mussini C.
- Mutairi A.A.
- Mutch R.
- Mwaura E.
- Mwaura L.
- Márquez L.
- Mägi R.
- Naaber P.
- Naderpour Zeinab
- Nadkarni Girish N.
- Nagra Imrun
- Naisbitt Jay
- Nakanishi T.
- Naranjo Andres
- Nasir Farah
- Nayak Monalisa
- Nazari R.
- Neal Alan
- Neale Benjamin M.
- Nencioni C.
- Neofytos D.
- Netherton K.
- Newell H.
- Newey Luke
- Newman J.
- Newman Tabitha
- Newton M.
- Ng Anthony
- Nguyen Huy
- Niavarani Ahmadreza
- Niblo Kristi
- Nichol Alistair
- Nicholson A.
- Nicholson A.
- Nicol L.
- Niemi Mari E.K.
- Nikitas N.
- Nilaratanakul Voraphoj
- Nilsson Anette.
- Nivard M.
- Nixon R.
- Nkambul L.
- Nkambul Lindokuhle
- Noble Harriet
- Nolan C.
- Norman K.
- Norris John
- Nortcliffe T.
- North J.
- North Kari
- Noto Keith
- Novis C.
- Nown Angela
- Nune A.
- Nussle S.G.
- Nwafor L.
- O'Brien L.
- O'Brien P.
- O'Connell A.M.
- O'Connell S.
- O'Connor Denise
- O'Connor Grainne
- O'Donnell C.J.
- O'Hara M.
- O'Leary R.
- O'Malley L.
- O'Neil Pauline
- O'Neill L.
- O'Reilly Kevin
- O'Reilly Paul
- O'Sullivan S.
- Oakley Naomi
- Oblak M.
- Odam M.
- Odhams Christopher A.
- Oetjens Matthew
- Ogg Bethan
- Ognibene A.
- Okasha Kamal
- Okeefe L.
- Oliveira M.
- Olufuwa Olumide
- Omar Z.
- Oosthuyzen Wilna
- Openshaw Peter
- Ori A.P.S.
- Ostermann Marlies
- Otahal I.
- Oxspring S.
- Paciosi F.
- Packer Richard J.
- Packham S.
- Padden Grace
- Page V.J.
- Pairo-Castineira Erola
- Pakou G.
- Palmer D.S.
- Palmieri M.
- Palotie A.
- Pancrazzi A.
- Panese S.
- Pappa Evita
- Paramsothy Remi
- Parati G.
- Parisi S.G.
- Park D.
- Park L.
- Parker R.
- Parkin J.
- Parkinson Nick
- Parkinson P.
- Parmar C.
- Parravicini P.
- Parris V.
- Parsons P.
- Partha R.
- Partridge R.
- Pasko D.
- Passmore H.
- Patch Christine
- Patel A.
- Patel B.
- Patel B.
- Patel Kamal
- Patel Mital
- Patel Tahera
- Paterson Trevor
- Pathak Gita
- Pathan Nazima
- Pattison N.
- Paul P.
- Pavlovic Milos
- Pawley C.
- Pearson Harriet
- Pearson S.
- Peasgood Emily
- Peloso G.
- Penacerrada M.
- Pendlebury J.
- Penn R.
- Pereira Alexandre C.
- Perez E.F.
- Perez J.
- Perez-Tur J.
- Perkins E.
- Perna R.
- Perola M.
- Perrella A.
- Perry J.
- Peruggia Michael
- Pessina G.
- Pesukova J.
- Peters Cecilia
- Peters M.J.
- Peterson P.
- Petitjean L.
- Petrocelli P.
- Petty Lauren E.
- Pheby Jane
- Philbin Jennifer
- Phillips Claire
- Phillips P.
- Phipps J.
- Phokaew Chureerat
- Phull Mandeep
- Piacentini P.
- Picchiotti N.
- Pickard A.
- Piercy C.
- Pigazzini S.
- Pinnell J.
- Pinoli P.
- Pinto A.M.
- Pinzuti Irene
- Pippard L.
- Pirinen Matti
- Piscopo C.
- Pitts S.
- Planas A.M.
- Player B.
- Pogreban Tatiana
- Pogson David
- Polgar O.
- Polgarova Petra
- Polikowski Hannah
- Polimanti Renato
- Pollard R.
- Polymeropoulos C.
- Polymeropoulos M.H.
- Polymeropoulos V.
- Pongpanich Monnat
- Ponting Chris P.
- Poole Alice
- Popescu M.
- Porteous David J.
- Poscente M.
- Pothecary Carla
- Potla Darsh
- Potoczna D.
- Potts Kathryn
- Poulaka M.
- Poultney U.
- Prady H.
- Prager Kirsty
- Praman K.
- Pratley A.
- Prendergast C.
- Prentice L.
- Preston Stephen
- Preuss Michael
- Price A.
- Price C.
- Price Richard
- Prime Zoe
- Pristopan V.
- Pritchard K.
- Proudfoot N.
- Prout R.
- Prysyazhna Oleksandra
- Przychodzen B.P.
- Pugh R.
- Purewal B.
- Purewal Manjit
- Purohit Dharam
- Purvis S.
- Putchareon Opass
- Puthanakit Thanyawee
- Puusepp M.
- Puxty Alex
- Puxty Kathryn
- Pye K.
- Qiu X.
- Quaid S.
- Queiroz Joana
- Quinn A.
- Quinn H.
- Quinodoz M.
- Quiros-Roldan E.
- Rad L.
- Rader D.
- Rader Daniel J.
- Radford E.
- Radhakrishnan Jayachandran
- Rafaels N.
- Raggi P.
- Ragoussis J.
- Rahmouni S.
- Rai Sabi Gurung
- Raimondi F.
- Raith E.
- Raithatha A.
- Raj M.
- Ramos L.
- Rancan I.
- Rand J.
- Rand K.
- Randell G.
- Ranga Poonam
- Rangarajan H.
- Rankin Tobias
- Ratnam V.
- Rattray A.
- Ravaglia S.
- Rawlik Konrad
- Rawlins John
- Ray S.
- Raynard Dana
- Reddy A.
- Reece-Anthony R.
- Reed A.
- Rees A.
- Rees S.
- Rees Tabitha
- Rehman Hafiz
- Reid K.
- Reimann E.
- Rekha P.
- Rendon Augusto
- Renieri A.
- Reschreiter H.
- Reyes A.
- Reynolds Jessica
- Rezk N.
- Rhead B.
- Rhead K.
- Rhodes Daniel
- Rhodes Joanne
- Rice P.
- Richards J.B.
- Richards Owen
- Richardson N.
- Riches J.
- Riches Katie
- Richmond Anne
- Rico V.
- Ridker P.M.
- Rikunenko R.
- Ringmets I.
- Ripamonti D.
- Ripatti S.
- Rishton Chloe
- Ritchie Marylyn D.
- Ritzema J.
- Riva A.
- Rivers V.
- Rivolta C.
- Rizzi M.
- Rizzo C.L.
- Roberts Belinda
- Roberts G.
- Robinson M.
- Robinson P.
- Robles V.
- Roche L.
- Roche Lisa
- Roche Samantha
- Rodden Natalie
- Roe N.
- Rogers N.
- Rogers P.
- Rogerson K.
- Rogne T.
- Rojo Roceld
- Rojo S.
- Romani D.
- Rooney Kevin
- Rooney L.
- Rooyackers O.
- Rosa A.D.
- Rosaroso Lace
- Rose Alastair
- Rose Steve
- Rossetti B.
- Rostron A.
- Rothwell J.
- Rovere M.T.L.
- Rowan Kathy
- Rowland-Jones S.
- Roy A.
- Roynon-Reed Anna
- Rudkin J.K.
- Ruiz Luong
- Ruiz-Jaén F.
- Runciman N.
- Ruotsalainen S.
- Rusconi S.
- Russell Clark D.
- Russo R.
- Ryan Lucy
- Ryan-Smith Janet
- Saad Samuel
- Sabrina R.
- Saeedi Morteza
- Safieh L.A.
- Saha R.
- Saha Rohit
- Saha Sian
- Sainsbury Hannah
- Salberg A.
- Salciute Erika
- Saleem Malik
- Salehi Shahla
- Salerni L.
- Salib Irene
- Salmi S.
- Salmon Karen
- Salutous D.
- Saluzzio Romina Pepermans
- Samakomva Tinashe
- Samir Amr
- Sampson Julia
- Sanarico M.
- Sanderson A.
- Sandhu Rajdeep
- Sangombe Mirriam
- Sanguinetti M.
- Sarathy V.
- Sargeant Janet
- Sarma G.
- Sarno L.D.
- Sarzi-Braga S.
- Sathe S.
- Satterstrom F.K.
- Saunderson A.
- Saunderson P.
- Sauvage A.S.
- Savill Heather
- Sawaji M.
- Scaggiante R.
- Scala R.
- Scanlon J.
- Schadt Eric E.
- Scherewode J.
- Schiaroli E.
- Scholefield B.
- Schon Katherine
- Schumacher N.
- Schurr E.
- Scolletta S.
- Scott Richard H.
- Scott T.
- Scott Zoe
- Scotton P.G.
- Scriven James
- Sealfon Stuart
- Seaman Rebecca
- Sebra Robert P.
- Seed C.
- Segala F.V.
- Segura T.
- Sell C.
- Sellick K.
- Selvanayagam S.
- Semple OBE Malcolm G.
- Semple Gary
- Senaratne D.
- Serra-Llovich A.
- Serrano-Heras G.
- Serrano-Ruiz A.
- Service J.
- Sesso H.D.
- Shah Nirav
- Shahin Doaa
- Shankar-Hari Manu
- Shanmugasundaram P.
- Sharififard Bahareh
- Shastri A.J.
- Shaw David
- Shaw Douglas M.
- Shaw L.
- Shaw R.
- Shelley B.
- Shelton J.F.
- Shelton S.
- Shen Xia
- Shepardson S.
- Shepherd A.
- Shiel Julian
- Shokkar R.
- Short A.
- Shortt J.
- Shotelersuk Vorasuk
- Shovelton C.
- Shrine Nick
- Shuker Karen
- Siano M.
- Sicat Christine
- Siddiq Afshan
- Silva Pedro
- Sim M.
- Simms Richard
- Simpson K.
- Simpson K.
- Singh Jayaprakash
- Singleton Jo
- Skinner D.
- Slater V.
- Slaughter M.
- Slawson Nicola
- Slevin K.
- Sloan Brendan
- Sloane G.
- Sloofman Laura G.
- Smedley Clare
- Smieszek S.P.
- Smith A.V.
- Smith E.
- Smith J.
- Smith J.
- Smith John
- Smith K.
- Smith L.
- Smith Matthew
- Smith Oliver
- Smith T.
- Smithson Elizabeth
- Smoller J.W.
- Smuts Sara
- Smyth D.
- Smyth M.
- Sobh Ali
- Sodsai Pimpayao
- Soler P.
- Sollesta Kathryn
- Solligard E.
- Solomonson Matthew
- Soranzo N.
- Soriano A.
- Sowter J.
- Spargi G.
- Spector T.D.
- Spencer C.C.A.
- Spencer K.
- Spencer S.
- Spertilli C.
- Spivey M.
- Springle Philippa
- Squeo G.M.
- Sri-Chandana C.
- Srikaran S.
- Stacey A.
- Stammers K.
- Starkopf J.
- Stead R.
- Stella A.
- Stenhouse Andrew
- Stephens D.
- Stephenson E.
- Stephenson L.
- Stevens Christine
- Stevenson L.
- Stewart R.
- Stickley J.
- Stoddard Emma
- Stone S.
- Stones E.
- Stowe B.
- Strachan D.
- Stroud Katerina
- Stroud Natalie
- Stuart Carmel
- Stuckey Alex
- Suardi C.
- Suarez Jose Cebrian
- Subramanian Deepak
- Subramanian G.
- Suchartlikitwong Pintip
- Suh N.
- Sukha A.
- Sukumaran A.
- Suliman B.A.
- Summers Charlotte
- Summers J.
- Sumoy L.
- Sun Y.V.
- Sundar Ashok
- Sundaram Radha
- Sutherland I.
- Sutherland S.B.
- Suttichet Thitima B.
- Swain Andrew
- Sweeney L.
- Sweet K.
- Swets Maaike
- Symon L.
- Symons A.
- Szakmany Tamas
- Szoor-McElhinney Helen
- Tabri J.
- Tacconi D.
- Tadi Hengameh A.
- Tagliavini E.
- Tamm A.
- Tampsett R.
- Taneski Filip
- Tanfoni M.
- Tang Lara
- Tardif N.
- Tariq A.
- Tatham K.C.
- Tavares S.
- Tavecchia L.
- Taylor A.
- Taylor June
- Taylor M.
- Taylor Melanie
- Tebbutt J.
- Templeton Maie
- Tench H.
- Tenesa Albert
- Tetla D.
- Texeira Joana
- Thanasi Maria
- Thankachen M.
- Thirlwall Yvette
- Thirumaran Muthu
- Thomas A.
- Thomas A.
- Thomas B.
- Thomas E.
- Thomas H.
- Thomas Jacqueline
- Thomas M.
- Thomas R.
- Thomas V.
- Thomis L.
- Thompsom Maria
- Thompson Christopher
- Thompson R.
- Thompson Ryan C.
- Thomson Nicola
- Thornton D.
- Thornton L.
- Thorpe C.
- Thrasyvoulou Laura.
- Thrush Jessica
- Thwaites V.
- Thys M.
- Tibke Clare
- Tierney Carey
- Tilbey S.
- Tilney Emma
- Timlick E.
- Timmers Paul R.H.J.
- Ting L.
- Tiseo G.
- Tita R.
- Tivenan H.
- Tobin Martin D.
- Todd A.
- Todd Linda
- Tolson M.
- Tomas A.L.
- Tommasi A.
- Tonks L.
- Torky Mohamed S.
- Torrents D.
- Torvorapanit Pattama
- Tracy B.
- Trankiem Amy
- Tranter Helen
- Trembath R.C.
- Tridente Ascanio
- Trim F.
- Trivedi B.
- Trodd D.
- Trogstad L.I.S.
- Trotman Sallyanne
- Trotta T.
- Trower H.
- Truman Nick
- Trumper E.
- Tsao P.
- Tselios C.
- Tsinaslanidis George
- Tsuo K.
- Tucci A.
- Tuckey V.
- Tully Redmond
- Tumbarello M.
- Turki S.
- Turley P.
- Turnbull A.
- Turner Keri
- Turner Lynne
- Turner P.
- Turner Victoria
- Turner-Bone I.
- Turney S.
- Turtle Lance
- Tutton R.
- Twiss S.
- Tyl David
- Tyler A.
- Uitterlinden A.G.
- Underwood Slayton J.
- Vaghi M.
- Vaida M.
- Valente S.
- Valentine J.
- Valentino F.
- van Blokland I.
- van Heel D.A.
- van Koutrik L.
- Varghese M.
- Vecchia M.
- Vedage D.
- Veerapen Kumar
- Venkatesh Harish
- Venn Laura D.
- Venturelli S.
- Vergori A.
- Verlander M.
- Verma Anurag
- Verma S.S.
- Vertue M.
- Verula J.
- Verzuri A.
- Vigurs Charlie
- Villalonga J.M.
- Vincent Rachel
- Vincenti A.
- Virgilio Emma
- Vitart Veronique
- Vizcaychipi M.P.
- Vochin A.
- Voide C.
- von Frenckell C.
- von Hohenstaufen Kathrin Aprile
- Vonk J.M.
- Vulesevic B.
- Vuylsteke A.
- Wackett Tony
- Wadams B.
- Waddington N.
- Wagstaff Veronica
- Wain Louise V.
- Waite Alicia A.C.
- Wakefield Phillipa
- Wakinshaw F.
- Waldron J.
- Walker D.
- Walker R.
- Walker S.
- Walker Susan
- Wall Alanna
- Walsh Timothy
- Walters R.K.
- Walton Olivia
- Wang Bo
- Wang J.
- Wang Xueyang
- Wanying Zhu
- Ward G.
- Ward Luke
- Ward Mairi
- Warden Scott
- Warmerdam R.
- Warren D.
- Wassall H.
- Wasson C.
- Watkins Claire
- Watson E.
- Watson G.
- Watson J.
- Watters M.
- Waugh Victoria
- Weaver Jane
- Webster A.
- Webster D.
- Webster K.
- Wei Shuying
- Weiss S.T.
- Weldon C.H.
- Wells C.
- Welters Ingeborg D.
- Weston H.
- Whileman A.
- Whitbread J.
- White Deborah
- White Ian
- White K.
- White M.
- White N.
- White N.
- Whiteley Simon
- Whiteside J.
- Whittle H.
- Whitton Christopher
- Whyte Clare
- Wicks S.J.
- Wilby Elizabeth
- Wilcox L.
- Wilcox R.
- Wild H.
- Wild Laura
- Wiles M.
- Wilkins J.
- Wilkinson Ami
- Wilkinson B.
- Willer C.
- Williams A.
- Williams A.
- Williams A.
- Williams Alexander T.
- Williams D.
- Williams E.
- Williams F.
- Williams Gemma
- Williams H.
- Williams Karen
- Williams Marie
- Williams P.
- Williams S.
- Williams Toran
- Willis C.
- Willis Heather
- Wills M.
- Willson J.
- Wilson A.
- Wilson D.J.
- Wilson James F.
- Wilson Jean
- Winnard Sarah
- Winter-Goodwin B.
- Wolf-Roberts R.
- Wolford Brooke N.
- Wong Joanna
- Wood D.
- Wood Hannah-Louise
- Wood Suzanne
- Wood T.
- Woodford C.
- Woodruff M.
- Woods L.
- Woodyatt Wiesia
- Woolley A.E.
- Worner R.
- Worsley L.
- Wray G.
- Wren L.
- Wright D.
- Wright J.
- Wright M.
- Wrobel Nicola
- Wu Yang
- Wulandari R.
- Wyllie D.H.
- Wynter I.
- Xavier Kugan
- Xue X.
- Yadav A.
- Yang Jian
- Yassen Amr M.
- Yates Brian
- Ye C.
- Yun Nikki
- Zainy Tala
- Zak Anne
- Zaki Ahmed
- Zamikula J.
- Zanella I.
- Zborowski A.C.
- Zeberg Hugo
- Zechner Marie
- Zguro K.
- Zhang M.
- Zhao J.H.
- Zheng Chenqing
- Zhou W.
- Zitter L.
- Zlatopolsky Menachem
- Zongo Olivier
- Zucchi P.
- Zyndorf Marissa
- Zöllner S.
- Åsvold Bjørn Olav
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease