Passive chevron replicator

There is described a passive replicator device to be used in magnetic bubble domain systems. The replicator is passive, i.e., does not require an active element such as a current source or the like, and both propagates and replicates bubble domains. In a preferred embodiment, the replicator uses chevron type elements arranged in an appropriate pattern so as to interact with a pair of propagation paths wherein bubble domains are propagated. A bubble in one propagation path is routinely transferred therealong and, concurrently, replicated by the instant device into another propagation path. A plurality of elements arranged in juxtaposition to the chevrons assists in controlling the propagation of the bubbles through the respective propagation paths and, at the appropriate time, provides a cutting action wherein a bubble which is elongated between the chevrons of the two propagation paths is split into two separate bubbles

Teaching, Learning and Leading with Schools and Communities: Preparing Sophisticated, Reflective, and Resilient Elementary STEM Educators

Loyola University Chicago’s Teaching, Learning and Leading with Schools and Communities (TLLSC) program is an ambitious break from traditional, university-based teacher preparation models. This clinically-based initial teacher preparation program, fully embedded in local schools and community organizations, takes an ecological perspective on the development of sophisticated, reflective, and resilient elementary science educators who are able to prepare and inspire students and act as agents of change in their schools. This paper describes how TLLSC leverages time for science across elementary teacher candidates’ entire program through an emphasis on practitioner inquiry and integrated (inter- and trans-disciplinary) teaching and learning. TLLSC’s innovative approach is designed to foster STEM habits of mind, integrate scientific practices, and support candidates’ ongoing self-examination of personal and social applications of science for themselves and their future students

Morphological characteristics of "Monterufoli horse"

Monterufoli horse is a local endangered breed of the Tuscany and derives from the omonym area in province of Pisa. This horse derives from local wild and extinct equines and has Maremmano, Tolfetano and Oriental ancestors. The mean and the standard deviation of biometric characters, and the absolut and percentage frequency of morphological characteristics were calculated. The measures of the adult females were estimated by ANOVA considering three different class of age. The average sizes were: height at withers of 135.4±6.3 and 129.2±5.9, thorax circumference of 166.4±8.3 and 163.4±8.9, frontshank circumference of 17.7±1.5 and 17.5±0.9, for males and females, respectively. All the observed horses presented dark coat. Monterufoli horses showed the physical characteristics of local extinct ancestors (Selvena pony), but also the characteristics of other breeds that contributed to improve the local population. This horse, which was once used in agriculture and for light draught, is now involved for saddle use

Evaluation of saddle and driving aptitudes in Monterufoli pony.

The Monterufoli pony is an endangered Tuscan breed. In the 80's began a project for the conservation of the breed and at present there are roughly 200 individuals. The equine was once utilized for saddle and driving and this study deals with the training for these two aptitudes. The mor- phologic type of the pony seems suited for saddle, in particular for children and beginners, and driving. The ponies showed developed chest, strong legs with short shanks: all these characters were useful for trot and driving. In this trial 3-4 years old never tamed Monterufoli ponies were opportunely choose and subsequently trained for saddle and driving. The ponies were submitted to the "aptitude test" for the two aptitudes and the results were good both for practical and character sides. The marks for sad- dle and driving were 8.16 and 8.06 respectively. Also the 3 ponies showed good results for the Aptitude Index: 7.60, 7.87 and 7.89. The results of the trial showed the excellent ability of the Monterufoli pony for saddle and driving. The good results of the test are important for the diffusion of the breed in the territory and in particular in horse centres and in equestrian tourism sites

Pulsed Current Effect on the Hard Anodizing of an AlSi10Mg Aluminum Alloy Obtained via Additive Manufacturing

The hard anodizing treatments of cast Al-Si alloys are notoriously difficult. Indeed, their microstructural features hinder the growth of a uniform, compact, and defect-free anodic oxide. In this paper, AlSi10Mg samples, produced via Gravity Casting (GC) and Additive Manufacturing, i.e., Laser Powder Bed Fusion (L-PBF), were hard anodized in a sulfuric acid bath, in order to verify how the particular microstructure obtained via L-PBF affects the thickness, hardness, compactness, and defectiveness of the anodic oxide. Moreover, for the first time, Pulsed Direct Current (PDC) procedures were used to perform the hard anodizing treatments on additively manufactured AlSi10Mg alloy. Several combinations of temperature and electrical parameters, i.e., current density, frequency, and Duty Cycle, were tested. The anodized samples were characterized through optical microscopy analysis, Scanning Electron Microscopy (SEM) analysis, and accelerated corrosion tests, i.e., Potentiodynamic Polarization (POL) and Electrochemical Impedance Spectroscopy (EIS) measurements. The PDC procedures allowed improvement of the compromise between evenness, compactness, and defectiveness. Among the attempted PDC procedures, a specific combination of electrical parameters and temperature allowed the best results to be obtained, i.e., the highest hardness and the lowest volumetric expansion values without compromising the oxide quality rating and the corrosion resistance behavior. However, none of the attempted PCD strategies allowed the hardness values obtained on samples produced via GC to be reached

Clinical Effects of Xanthine Oxidase Inhibitors in Hyperuricemic Patients.

open5noThis review aims to critically present the available clinical evidence supporting the treatment of chronic hyperuricemia with xanthine oxidase inhibitors. For this reason, the studies published on uric acid (UA)-lowering drugs in the English language from 2000 to August 2019 have been carefully reviewed. The terms "serum uric acid," "xanthine oxidase," "allopurinol," "febuxostat," and "topiroxostat" were incorporated into an electronic search strategy, alone and in combinations, in both MEDLINE (National Library of Medicine, Bethesda, MD) and the Cochrane Register of Controlled Trials (The Cochrane Collaboration, Oxford, UK). Even if new urate-lowering drugs seem of particular efficacy for acute treatment of refractory hyperuricemia, their use is supported by relatively small clinical evidence. On the contrary, large long-term clinical trials have demonstrated that xanthine oxidase inhibitors (XOIs, namely, allopurinol and febuxostat) are effective, safe, and relatively well-tolerated in most of the patients. They have mainly been tested in the elderly, in patients affected by chronic diseases such as heart failure and cancer, and in patients taking a large number of drugs, confirming their safety profile. Recent data also show that they could exert some positive effects on vascular health, renal function, and glucose metabolism. Their cost is also low. In conclusion, XOIs remain the first choice of UA-lowering drug for chronic treatment.openCicero AFG, Fogacci F, Cincione RI, Tocci G, Borghi C.Cicero AFG, Fogacci F, Cincione RI, Tocci G, Borghi C

morphological characteristics of amiata donkey reared in tuscany

In this work were studied morphological characteristics and biometric parameters of the Amiata donkey. The Amiata donkey is a local endangered breed and derives from the homonym mountain in Tuscany. This donkey, which was used, over the past, like pack animal in farms and in mines, is now involved in milk production, onotherapy and trekking. The averages and the standard deviations of the biometric parameters and the frequency of the morphological characters of foals, adult females and stallions were calculated. The measures of the adult females were estimated by ANOVA considering three different classes of age: 3-4, 5-6, over6yearsold. 3-4, 5-6, over 6 years old.. The average sizes were: height at withers of 129.8±4.7and125.8±5.6cm,thoraxcircumferenceof145.6±7.8and145.0±7.8cm, 129.8±4.7 and125.8±5.6cm,thoraxcircumferenceof145.6±7.8and145.0±7.8cm, and 125.8±5.6cm,thoraxcircumferenceof145.6±7.8and145.0±7.8cm, 125.8±5.6 cm,thoraxcircumferenceof145.6±7.8and145.0±7.8cm, , thorax circumference of 145.6±7.8and145.0±7.8cm, 145.6±7.8and145.0±7.8cm, and 145.0±7.8cm, 145.0±7.8 cm,, front shank circumference of 18.3±0.8and16.9±1.5cm,forstallionsandadultfemalesrespectively.All 18.3±0.8 and16.9±1.5cm,forstallionsandadultfemalesrespectively.All and 16.9±1.5cm,forstallionsandadultfemalesrespectively.All 16.9±1.5 cm,forstallionsandadultfemalesrespectively.All , for stallions and adult females respectively. All the observed donkeys presented dark grey coat with the shoulder stripe. The zoometric indices of the adult females did not differ between the classes and showed that the somatic adult proportions had al- ready reached in 3-4 years old donkeys. This breed showed the features of the ancestors: the shoulder stripe of the Equus asinus africanus and the legs stripes of the Equus asinus somaliensis

Structure of a model TiO2 photocatalytic interface

The interaction of water with TiO2 is crucial to many of its practical applications, including photocatalytic water splitting. Following the first demonstration of this phenomenon 40 years ago there have been numerous studies of the rutile single-crystal TiO2(110) interface with water. This has provided an atomic-level understanding of the water-TiO2 interaction. However, nearly all of the previous studies of water/TiO2 interfaces involve water in the vapour phase. Here, we explore the interfacial structure between liquid water and a rutile TiO2(110) surface pre-characterized at the atomic level. Scanning tunnelling microscopy and surface X-ray diffraction are used to determine the structure, which is comprised of an ordered array of hydroxyl molecules with molecular water in the second layer. Static and dynamic density functional theory calculations suggest that a possible mechanism for formation of the hydroxyl overlayer involves the mixed adsorption of O2 and H2O on a partially defected surface. The quantitative structural properties derived here provide a basis with which to explore the atomistic properties and hence mechanisms involved in TiO2 photocatalysis

The European Union, borders and conflict transformation: the case of Cyprus

Much of the existing literature on the European Union (EU), conflict transformation and border dynamics has been premised on the assumption that the nature of the border determines EU intervention and the consequences that flow from this in terms of EU impact. The article aims to transcend this literature through assessing how domestic interpretations influence EU border transformation in conflict situations, taking Cyprus as a case study. Moreover, the objective is to fuse the literature on EU bordering impact and perceptions of the EU’s normative projection in conflict resolution. Pursuing this line of inquiry is an attempt to depart from the notion of borders being constructed solely by unidirectional EU logics of engagement or bordering practices to a conceptualization of the border as co-constituted space, where the interpretations of the EU’s normative projections by conflict parties, and the strategies that they pursue, can determine the relative openness of the EU border

Upgrade of the fast analogue intra-pulse phase feedback at SPARC_LAB

SPARC_LAB is a facility designed for the production of FEL radiation and the exploration of advanced acceleration techniques using a high brightness electron photo-injector. Specifically, particle-driven plasma wakefield acceleration (PWFA) necessitates exceptional beam stability, in order to minimize the jitter between the driver and witness beams. This requirement directly translates into RF phase jitter minimization, since a velocity bunching (RF compression) working point is employed at SPARC_LAB for acceleration. In the past, a fast intra-pulse phase feedback system has been developed to stabilize the klystron RF pulse. This allowed to reach a phase stability of S-band power units (both driven by PFN modulators) below 50 fs rms. However, in order to meet the more stringent requirements of PWFA scheme, some upgrades of this feedback system have been recently carried out. A prototype has been tested on a C-band klystron driven by a solid-state modulator, in order to investigate the possibility for an additional improvement resulting from the inherently more stable power source. In this paper the preliminary measurement results obtained at SPARC_LAB after such upgrades will be reviewed.Comment: Talk presented at LLRF Workshop 2023 (LLRF2023, arXiv: 2310.03199