40 research outputs found
Physical and virtual water transfers for regional water stress alleviation in China
Water can be redistributed through, in physical terms, water transfer projects and virtually, embodied water for the production of traded products. Here, we explore whether such water redistributions can help mitigate water stress in China. This study, for the first time to our knowledge, both compiles a full inventory for physical water transfers at a provincial level and maps virtual water flows between Chinese provinces in 2007 and 2030. Our results show that, at the national level, physical water flows because of the major water transfer projects amounted to 4.5% of national water supply, whereas virtual water flows accounted for 35% (varies between 11% and 65%at the provincial level) in 2007. Furthermore, our analysis shows that both physical and virtualwater flows do not play a major role in mitigating water stress in the water-receiving regions but exacerbate water stress for the water-exporting regions of China. Future water stress in the main water-exporting provinces is likely to increase further based on our analysis of the historical trajectory of the major governing socioeconomic and technical factors and the full implementation of policy initiatives relating to water use and economic development. Improving water use efficiency is key to mitigating water stress, but the efficiency gains will be largely offset by the water demand increase caused by continued economic development. We conclude that much greater attention needs to be paid to water demand management rather than the current focus on supply-oriented management
City level water withdrawal and scarcity accounts of China
In the context of Chinaâs freshwater crisis high-resolution data are critical for sustainable water management and economic growth. Yet there is a dearth of data on water withdrawal and scarcity regardless of whether total or subsector amount, for prefectural cities. In administrative and territorial scope, we accounted for water withdrawal of all 63 economic-socio-environmental sectors for all 343 prefectural cities in China, based on a general framework and 2015 data. Spatial and economic-sector resolution is improved compared with previous studies by partitioning general sectors into industrial and agricultural sub-sectors. Construction of these datasets was based on selection of 16 driving forces. We connected a size indicator with corresponding water-withdrawal efficiency. We further accounted for total blue-water withdrawal and quantitative water scarcity status. Then we compared different scopes and methods of official accounts and statistics from various water datasets. These disaggregated and complete data could be used in input-output models for municipal design and governmental planning to help gain in-depth insights into subsector water-saving priorities from local economic activities
Foods advertised in US weekly supermarket sales circulars over one year: a content analysis
BACKGROUND: The nutritional content of Americansâ shopping carts is suboptimal despite federal dietary guidance, in this case, the MyPlate consumer icon which displays desired proportions of vegetables, fruits, dairy, grains and protein foods for consumption. Consumers mention print advertisingâsuch as weekly sales circularsâfrequently as influencing their grocery shopping decisions. METHODS: To examine and describe the relative proportions of advertised foods aggregated into the MyPlate food grouping system, a content analysis of 9 209 foods advertised in 52 weekly supermarket newspaper sales inserts in 2009 from a local grocery chain was conducted in a Midwestern community. RESULTS: Overall, the protein foods group was most often represented in sales circulars (25% of total items), followed by grains (18%); dairy (10%); vegetables (8%) and fruits (7%). Less than 3% of sales advertisements were for dark green and red & orange vegetables. Over twice as much whole fruit versus 100% fruit juice was advertised (70% vs. 30%, respectively; Pâ<â0.001). Significantly fewer protein foods and more grains than expected were advertised in the fall, and slightly more dark green vegetables were advertised in winter and spring than in summer and fall (Pâ=â0.05). CONCLUSIONS: The average American diet, including underconsumption of fruits and vegetables but overconsumption of protein foods, was reflected in the relative frequency of food groups advertised in weekly sales circulars. Modifying sales circulars to represent healthier food groups may preserve retail profits (considering these groupsâ higher profit margin) while promoting adherence to federal dietary guidance
PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models
SummaryPhosphoinositide-3 kinase (PI3K)-δ and PI3K-γ are preferentially expressed in immune cells, and inhibitors targeting these isoforms are hypothesized to have anti-inflammatory activity by affecting the adaptive and innate immune response. We report on a potent oral PI3K-δ and PI3K-γ inhibitor (IPI-145) and characterize this compound in biochemical, cellular, and in vivo assays. These studies demonstrate that IPI-145 exerts profound effects on adaptive and innate immunity by inhibiting B and T cell proliferation, blocking neutrophil migration, and inhibiting basophil activation. We explored the therapeutic value of combined PI3K-δ and PI3K-γ blockade, and IPI-145 showed potent activity in collagen-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus rodent models. These findings support the hypothesis that inhibition of immune function can be achieved through PI3K-δ and PI3K-γ blockade, potentially leading to significant therapeutic effects in multiple inflammatory, autoimmune, and hematologic diseases
Burden-shifting of water quantity and quality stress from mega-city Shanghai
Much attention has been paid to burden-shifting of CO2 emissions from developed regions to developing regions through trade. However, less discussed is that trade also acts as a mechanism enabling wealthy consumers to shift water quantity and quality stress to their trading partners. In this study we investigate how Shanghai, the largest mega-city in China, draws water resources from all over China and outsources its pollution through virtual quantity and quality water flows associated with trade. The results show that Shanghaiâs consumption of goods and services in 2007 led to 11.6 billion m3 of freshwater consumption, 796 thousand tons of COD, and 16.2 thousand tons of NH3-N in discharged wastewater. Of this, 79% of freshwater consumption, 82.9% of COD and 82.5% of NH3-N occurred in other Chinese Provinces which provide goods and services to Shanghai. Thirteen Provinces with severe and extreme water quantity stress accounted for 60% of net virtual water import to Shanghai, while 19 Provinces experiencing water quality stress endured 79% of net COD outsourcing and 75.5% of net NH3-N outsourcing from Shanghai. In accordance with the three âredlinesâ recently put forward by the Chinese central government to control water pollution and cap total water use in all provinces, we suggest that Shanghai should share its responsibility for reducing water quantity and quality stress in its trading partners through taking measures at provincial, industrial and consumer levels. In the meantime, Shanghai needs to enhance demand side management by promoting low water intensity consumption
Influence of design and media amendments on the performance of stormwater biofilters
Biofiltration systems are a promising retrofit option for site-constrained urban areas due to the vertical arrangement of treatment stages that leads to a relatively compact footprint. Existing knowledge about the influence of their design and configuration on hydrological, stormwater pollutant removal and long-term performance is limited and this has been identified as a barrier to their widespread uptake. Long-term simulations of lined and unlined biofiltration systems in four contrasting UK climatic regimes were used to assess the influence of climate, ponding depth, biofilter to drainage area ratio and infiltration rate on hydrological performance. The results showed that local differences in climate have a significant impact on performance and that infiltration rates as low as 0¡36âmm/h are not suitable for locations in the UK with high rainfall unless the biofilter to drainage area ratio is greater than 10%. However, with higher infiltration rates (72âmm/h) a biofilter occupying only 3% of the impermeable catchment area would be capable of infiltrating 97% of annual rainfall in central England. Preliminary results of adsorption and column tests to assess the effectiveness of media amendments, specifically zeolite and granular activated carbon, for dissolved copper and phosphate removal are presented in this paper
An Updated Review of Interventions that Include Promotion of Physical Activity for Adult Men
The marked disparity in life expectancy between men and women suggests men are a vulnerable group requiring targeted health promotion programs. As such, there is an increasing need for health promotion strategies that effectively engage men with their health and/or illness management. Programs that promote physical activity could significantly improve the health of men. Although George et al. (Sports Med 42(3):281, 30) reviewed physical activity programs involving adult males published between 1990 and 2010, developments in menâs health have prompted the emergence of new sex- and gender-specific approaches targeting men. The purpose of this review was to: (1) extend and update the review undertaken by George et al. (Sports Med 42(3):281, 30) concerning the effectiveness of physical activity programs in males, and (2) evaluate the integration of gender-specific influences in the content, design, and delivery of menâs health promotion programs. A search of MEDLINE, CINAHL, ScienceDirect, Web of Science, PsycINFO, the Cochrane Library, and the SPORTDiscus databases for articles published between January 2010 and August 2014 was conducted. In total, 35 studies, involving evaluations of 31 programs, were identified. Findings revealed that a variety of techniques and modes of delivery could effectively promote physical activity among men. Though the majority of programs were offered exclusively to men, 12 programs explicitly integrated gender-related influences in male-specific programs in ways that recognized menâs interests and preferences. Innovations in male-only programs that focus on masculine ideals and gender influences to engage men in increasing their physical activity hold potential for informing strategies to promote other areas of menâs health