7 research outputs found

    Life+ pullonkaulat: EU:n ympäristöalan rahoitusvälineen Life+ käytön esteet, haasteet ja parannusehdotukset

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    Euroopan ympäristöhankkeiden rahoitusväline Life rahoittaa erityisesti tutkimustiedon käytännön hyödyntämiseen tähtääviä laajoja hankkeita. Suomeen maksettava Life+ -rahoitus on suuruusluokaltaan noin 6–10 miljoonaa euroa/vuosi. Tämä ei kuitenkaan tule meille automaattisesti vaan riippuu täysin suomalaishankkeiden määrästä ja laadusta. Tässä julkaisussa identifioidaan tekijöitä, joita potentiaaliset hakijat kokevat ongelmallisiksi ja toisaalta myönteisiksi Life+ -ohjelmassa ja esitetään suosituksia rahoitusvälineen käytön kehittämiseksi maassamme

    Viljelykasvustojen selkärangattomat eläimet

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    Two novel genomic regions associated with fearfulness in dogs overlap human neuropsychiatric loci

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    Anxiety disorders are among the leading health issues in human medicine. The complex phenotypic and allelic nature of these traits as well as the challenge of establishing reliable measures of the heritable component of behaviour from the associated environmental factors hampers progress in their molecular aetiology. Dogs exhibit large natural variation in fearful and anxious behaviour and could facilitate progress in the molecular aetiology due to their unique genetic architecture. We have performed a genome-wide association study with a canine high-density SNP array in a cohort of 330 German Shepherds for two phenotypes, fear of loud noises (noise sensitivity) and fear of strangers or in novel situations. Genome-widely significant loci were discovered for the traits on chromosomes 20 and 7, respectively. The regions overlap human neuropsychiatric loci, including 18p11.2, with physiologically relevant candidate genes that contribute to glutamatergic and dopaminergic neurotransmission in the brain. In addition, the noise-sensitivity locus includes hearing-related candidate genes. These results indicate a genetic contribution for canine fear and suggest a shared molecular aetiology of anxiety across species. Further characterisation of the identified loci will pave the way to molecular understanding of the conditions as a prerequisite for improved therapy.Peer reviewe

    Optical energy transfer and loss mechanisms in coupled intracavity light emitters

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    | openaire: EC/H2020/638173/EU//iTPXPeer reviewe
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